中考生心理健康水平的多因素回归分析

目的了解中考生的心理健康水平及相关因素.方法采用症状自评量表(SCL-90)和防御方式问卷(DSQ)等对203名初三毕业班中考生进行测评.结果中考生SCL-90总分及强迫、人际关系敏感、抑郁、焦虑、敌对、恐怖、偏执、精神病性、其他9个因子均分高于初三学生常模(P<0.05～0.01);中考生的不成熟防御机制评分高于大学生,成熟型和中间型防御机制评分低于大学生(P<0.01);以SCL-90总分为因变量进行多因素回归分析,不成熟防御机制和中考信心两个变量进入回归方程,Y=75.627+29.364(不成熟型)-10.911(中考信心).结论中考生存在较为广泛而明显的心理健康问题,过多动用不成熟心理防御机制是导致心理健康水平下降的主要原因之一,中考信心则有助于缓解症状痛苦水平,促进心理健康水平的提高.     

中学生防御方式与心理健康的相关分析

目的：了解中学生心理防御机制及与心理健康的关系。方法：采用等御方式问卷（DSQ）和症状自评量表（SCL－90）对203名中学生进行调查测评。结果：DSQ4个因子评分在男女性间和报考重点中学与否组间差异无显著性（P＞0．05）,以初三学生SCL－90常模均分为界值,高症状组的不成熟型因子、中间型因子和掩饰度高于低症状组（（P＜0．01）,且与SCL－90总分及躯体化、强迫、人际敏感、抑郁、焦虑、敌对、恐怖、偏执、精神病性和其他症呈不同程度的正相关（P＜0．01）;成熟因子在两组间差异无显著见习生 （P＞0．05）。结论中老先生心理总痛苦水平与过多动用不成熟型、中间型防御机制及过度掩饰有关,须引起学校,家庭的高度重视。     

女性吸毒者心理防御机制及心理健康状况研究

目的探讨女性吸毒者的心理防御机制与心理状况及二者的关系。方法分别用防御方式问卷(DSQ)和症状自评量表(SCL 90),对110名女性吸毒者(研究组)和41名女大学生(对照组)进行调查。结果研究组不成熟防御机制、中间型防御机制和掩饰因子评分( 4. 83±0. 97, 4. 99±0. 75, 5. 98±1. 17)显著高于对照组(3. 95±0. 68, 4. 26±0. 73, 5. 41±1. 34) (P<0. 01或P<0. 05);研究组SCL 90中9个因子评分均显著高于对照组(P<0. 01);相关分析发现,研究组不成熟防御机制与SCL 90中9个因子均存在非常显著正相关(P<0. 01),中间型防御机制与SCL 90中的强迫、偏执、躯体化、抑郁存在显著正相关(P<0. 01或P<0. 05),掩饰因子与SCL 90中的敌对、偏执、强迫呈显著正相关(P<0. 01或P<0. 05)。结论女性吸毒者过多地使用不成熟防御机制及中间型防御机制,心理状况差,且二者存在明显的相关性。     

高中生防御方式与心理健康的关系

目的了解高中学生防御方式与心理健康的关系。方法采用整群抽样方法 ,抽取乐昌市高中一至三年级学生共 5 18名 ,对他们进行症状自评量表 (SCL 90 )及防御方式量表 (DSQ)测查 ,对结果采用典型相关分析方法进行统计分析。结果典型因素V由SCL 90的 9个因子共同反映 ,典型因素W主要由投射、被动攻击、潜意显现、抱怨、幻想、退缩等不成熟防御方式反映 ;典型因素V与W的典型相关系数 r=0 .64 4(P <0 .0 0 1)。结论在防御机制当中 ,主要是不成熟防御机制运用的频度及过度掩饰与高中生心理健康水平有关 ,因而应加强引导学生减少不成熟防御机制的运用。     

中学生防御方式与心理健康的相关分析

目的了解中学生心理防御机制及与心理健康的关系。方法采用防御方式问卷（DSQ）和症状自评量表（SCL-90）对203名中学生进行调查测评。结果 DSQ4个因子评分在男女生间和报考重点中学与否组间差异无显著性（P>0.05);以初三学生SCL-90常模均分为界值,高症状组的不成熟型因子、中间型因子和掩饰度高于低症状组（P<0.01),且与SCL-90总分及躯体化、强迫、人际敏感、抑郁、焦虑、敌对、恐怖、偏执、精神病性和其他症状呈不同程度的正相关（P<0.01);成熟因子在两组间差异无显著性（P>0.05)。结论中考生心理总痛苦水平与过多动用不成熟型、中间型防御机制及过度掩饰有关,须引起学校、家庭的高度重视。     

某大学医学生心理健康状况及其影响因素调查

目的 :调查某大学医学生心理健康状况及其影响因素 ,为提高医学大学生的心理健康水平提供心理学依据。方法 :随机抽取某大学医学生 314人 ,采用精神症状自评量表 (SCL 90 )、艾森克个性问卷 (EPQ)、生活事件调查表 (LES)以及一般情况调查表 ,调查分析医学大学生的心理健康状况及其影响因素。结果 :除躯体化因子外 ,大学医学生SCL 90其余各因子得分均高于全国青年组常模 (P <0 .0 5或 0 .0 1)。是否独生子女、不同家庭气氛学生的心理健康状况差异有统计学意义 (P <0 .0 5 )。逐步回归分析表明 ,负性生活事件分值及EPQ之N分高、家庭气氛不融洽 ,则SCL 90总分高。结论 :社会文化环境中的不良生活事件、情绪不稳定的人格特征、家庭气氛是医学大学生心理健康水平的影响因素之一。     

潍坊某监狱寻衅滋事人员心理健康状况与心理防御方式关系探讨

目的了解寻衅滋事服刑人员心理健康状况及心理防御机制方式,为服刑人员的心理健康教育提供科学依据。方法采用症状自评量表(SCL-90)和防御方式问卷(DSQ)对218名寻衅滋事服刑人员进行问卷调查;采用同样方法对监狱工作人员88名进行相关的问卷调查。结果寻衅滋事服刑人员不成熟型防御机制、成熟型防御机制和掩饰因子均分明显高于对照组(P0.01);SCL-90量表总均分及各因子分均明显高于对照组,差异有显著性(P0.01);不成熟型防御机制因子、掩饰因子与其SCL-90各因子显著相关(P均0.01)。结论寻衅滋事人员的心理防御方式对其心理健康状态具有重要影响。     

卖淫妇女心理防御机制及心理健康状况研究

目的探讨卖淫妇女的心理防御机制与心理状况以及二者的关系.方法分别用防御方式问卷(DSQ)和症状自评量表(SCL-90)对83名卖淫妇女(研究组)和41名女大学生(对照组)进行调查.结果研究组不成熟防御机制、中间型防御机制评分[(4.78±1.02)分,(4.96±0.86)分]均高于对照组[(3.95±0.68)分,(4.26±0.73)分](P＜0.01);研究组SCL-90中9个因子评分均显著高于对照组(P＜0.01);相关分析发现,研究组不成熟防御机制与SCL-90中9个因子均存在显著正相关(P＜0.01),中间型防御机制与SCL-90中9个因子也存在显著正相关(P＜0.01或P＜0.05),掩饰因子与SCL-90中的强迫、敌对、偏执、躯体、抑郁呈正相关(P＜0.01或P＜0.05).结论卖淫妇女过多地使用不成熟防御机制及中间型防御机制,心理状况差,且二者存在明显的相关性.     

应对方式及相关因素对医学生心理健康的影响

目的 :探讨医学生心理健康和应对方式的相关关系。方法 :对杭州师范学院医学院医学生共 2 36人 ,进行了心理健康评定量表 (SCL 90 )和应对方式问卷 (SCQ)测试。结果 :( 1)医学生中女生在解决问题 (t =- 2 75 ,P <0 0 1)、求助 (t=- 3 0 3,P <0 0 1) 2个因子分上显著高于男生 ,而合理化 (t=4 5 0 ,P <0 0 1)因子分显著低于男生 ;独生子女在求助、自责和幻想 3个因子上显著低于非独生子女 (P <0 0 1)。 ( 2 )不成熟型应对方式 (自责、幻想和退避 )与SCL 90的 9个因子均呈显著正相关 ;成熟型应对方式与SCL 90的 3个因子呈显著负相关 (P <0 0 5 )。 ( 3)SCQ各因子与心理健康水平的回归分析表明 ,自责和幼想 2个因子进入了对心理健康水平的回归方程 ,对心理健康状况的预测作用较大。结论 :应对方式对医学生心理健康状况有影响作用     

女性吸毒者心理防御机制及心理健康状况研究

目的探讨女性吸毒者的心理防御机制与心理状况及二者的关系.方法分别用防御方式问卷(DSQ)和症状自评量表(SCL-90),对110名女性吸毒者(研究组)和41名女大学生(对照组)进行调查.结果研究组不成熟防御机制、中间型防御机制和掩饰因子评分(4.83±0.97,4.99±0.75,5.98±1.17)显著高于对照组(3.95±0.68,4.26±0.73,5.41±1.34)(P＜0.01或P＜0.05);研究组SCL-90中9个因子评分均显著高于对照组(P＜0.01);相关分析发现,研究组不成熟防御机制与SCL-90中9个因子均存在非常显著正相关(P＜0.01),中间型防御机制与SCL-90中的强迫、偏执、躯体化、抑郁存在显著正相关(P＜0.01或P＜0.05),掩饰因子与SCL-90中的敌对、偏执、强迫呈显著正相关(P＜0.01或P＜0.05).结论女性吸毒者过多地使用不成熟防御机制及中间型防御机制,心理状况差,且二者存在明显的相关性.     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

BLOOD PRESSURE CHANGE WITH AGE IN SALT-SENSITIVE TEENAGERS

Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P＜ 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P＜ 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.     

安心颗粒对急诊经皮冠状动脉介入术后生活质量影响的研究

目的：评价使用安心颗粒对急诊经皮冠状动脉介入术（PPCI）术后生活质量的影响.方法：将160例接受PPCI的急性ST段抬高型心肌梗死患者随机分为安心颗粒组（术前顿服安心颗粒8.8g,术后安心颗粒4.4 g/次,每日2次）和对照组（仅接受基础药物治疗）.所有患者均服用阿司匹林、氯吡格雷和阿托伐他汀.分别在入院时、出院前1d、出院后180 d时,应用心肌梗死多维度量表（MIDAS）、中文版SF-36评价量表对患者生活质量评分.并观察术后30 d以内的出血并发症、血小板减少症发生情况.结果：入院时和出院前1d,两组患者的心肌梗死MIDAS、SF-36量表评分比较无差异（P＞0.05）;出院后180 d时,与对照组比较,安心颗粒组MIDAS、SF-36评分明显减低（P＜0.05）;组内与入院时比较,两组出院前1d、出院后180 d时,MIDAS、SF-36评分均降低（P＜0.05）.两组患者在随访期间均无大量出血、少量出血、重度和极重度血小板减少症发生,安心颗粒组有4例、对照组有7例发生不明显出血（P＞0.05）.两组发生轻度血小板减少症的患者数比较无差异（P＞0.05）.结论：PPCI使用安心颗粒,能改善急性ST段抬高型心肌梗死患者的生活质量,且不增加出血风险.     

The comparative studies of the influences of Urapidil and Nicardipine on sino-atrial node function, atrio-ventricular node function and hemodynamics

Objective:To investigate the influences of urapidil and nicardipine on rabbit sinus function,atrio-ventricular node function and hemodynamics.Methods:Thirty-two Angora's rabbits were selected and randomly divided into four groups.U1 group:urapidil 0.25 mg/kg;U2 group:urapidil 0.5 mg/kg;N1 group:nicardipine 10 μg/kg;N2 group:nicardipine 20 μg/kg.All these medicine were administrated within 30 seconds.Measurements were taken before and after the administration of urapidil or nicardipine for the following data:mean blood pressure(MAP),heart rate(HR),sino-atrial conduction time(SACT),maximal sinoatrial recovery time(SNRTmax)corrected sinus node recovery time(CSNRT),index of sinus node recovery time(SNRTI),Wenckebach A-V conduction frequency (WB),and P-R interval.Results:Significant MAP and HR changes were identified in all of the four groups before and after administration of both urapidil and nicardipine.No significant changes could be found in the rest of the parameters.Intergroup analysis showed that SACT and CSNRT of N1 and N2 groups were shorter than those of the U2 group(P＜0.01);the MAP decreased(P＜0.01)and the HR increased drastically(P＜0.01).Conclusions:Neither urapidil(0.25 mg/kg,0.5 mg/kg)nor nicardipine(10μg/kg,20μg/kg)has any significant influence on rabbit sinus function or rabbit atrio-ventricular node function.Nicardipine could be a better choice than urapidil for parafunctional sinus node patients.     

Expression of OPGmRNA and ODFmRNA in the patients of hip fracture due to osteoporosis

Objective：To investigate the gene expression of osteoprotegerin（OPG） and osteoclast differentiation factor（ODF） in the bone tissue of patients with hip fracture due to osteoporosis. Methods：OPGmRNA and ODFmRNA in the bone tissue in 50 cases of osteoporosis sufferers（over 50 years old） with hip fracture（Observer Group） and 30 cases of hip facture sufferers with no osteoporosis（Control group） were analyzed with the Semi-Quantitative RT-PCR method. Results：The mRNA expressed of ODF, OPG were both high in the patients with hip fracture. In the control group, the expression of OPG mRNA was observed, while the expression of ODF mRNA was very slight. Conclusion：Aged patients contained all signals including OPG, ODF that are essential for inducing osteoclastogenesis and promoting bone resorption.     

The clinicopathological and immuohistochemical analysis of solid-pseudopapillary tumor of the pancreas： report of 9 cases

Objective：To investigate the clinical features, pathological characteristics and immunophenotype of solid-pseudopapillary tumor of the pancreas（SPTP）. Methods：Nine surgically treated cases of SPTP were retrospectively reviewed. Hematoxylin and Eosin（HE） staining and immunohistochemical staining were used to analyze all cases, and the general clinical data was collected. Results：Six patients were asymptomatic except for a palpable mass. Two patients complained of vague-epigastric pain. One patient appeared jaundice. The tumor was encapsulated and solid tissues alternately with cystic tissues. Histologically, the histological structure of solid portion was pseudopapillary with a fibrovascular core. Tumor cells were uniform and medium-sized which were arranged in sheets ets or nests or pseudopapillary patterns. Immunohistochemical studies demonstrated that SPTP proved positive in vimentin（9/9 cases）, AAT（9/9 cases）, NSE（9/9 cases）, ACT（7/9 cases）, CK20（2/9 cases）, CgA（1/9 cases）, S-100（3/gcases）, PR（4/gcases）, Syn（3/9 cases） and CD56（5/9cases）, negative in CEA and ER. Conclusion：SPTP is a tumor predominantly occurring in young women frequently without special symptoms. This tumor has various characteristical histological patterns with different immunophenotype.     

Dynamic Changes in Serum Estradiol and Progesterone levels in Patients of Premenstrual Syndrome with Adverse Flow of Liver-qi

Objective:To probe into the influence of changes of ovarian hormones on the pathogenesis of the specific sub-type premenstrual syndrome(PMS)and reveal partial microcosmic mechanisms of adverse flow of liver-qi.Methods:Estradiol(E2)and progesterone(P)levels in serum were determined at different phases of menstrual cycle by radioimmunoassay.Results:In the group of PMS with adverse flow of liver-qi.the secretive peak value Of E2 and P at the follicular phase significantly decreased,and the secretive peak value at the luteal phase did not come into being.Conclusions:Low E2 and P secretive peak at the follicular phase and absence of secretive peak at the luteal phase is one of the microcosmic mechanisms of PMS with adverse flow of liver-qi.One of the pathophysiologic mechanisms of specific sub-type PMS is probably the continuous low level of E2and P.     

Real-time Three-dimensional Echocardiography in Assessment of Left Ventricular and Right Ventricular Volumes

Real-time three-dimensional echocardiography (RT3DE)is a new ultrasound technique that enables dynamic threedimensional visualization and quantification of the heart in real time. Investigation of feasibility and methodology of RT3DE in determining left ventricular (LV) and right ventricular (RV) volumes, RT3DE was performed in 35 normal adults using Philips SONOS 7500 system with a 2-4 MHz matrix array transducer. The 60°×60° "pyramid" volume database was obtained and analyzed on a TomTec echo workstation. Both LV and RV volumes were calculated with four 3DE methods (i.e. apical 2, 4, 8, and 16-plane) through manually tracing ventricular endocardial borders in end diastole and end systole. Stroke volumes were then calculated. LV volume was also measured by 2DE Simpson's rule using GE VIVID 7 ultrasound machine.     

SCREENING FOR A 21-CHROMOSOME ABNORMALITY IN PREIMPLANTED EMBRYOS OF ELDERLY WOMEN

Increasing maternal age is the only etiological factor unequivocally linked to Down's syndrome in humans. The occurrence rate of newborns with Down's syndrome is about 1/220 in women over 35 years old. However, the occurrence rate in embryos fertilized in vitro, of the elder woman is unclear. Using FISH we screened the number of chromosome 21 in preimplanted embryos of 5 elderly women (average age, 38.4 years) to study the feasibility and necessity of screening trisomy 21 in embryos in patients over 35 years old at the in vitro fertilization (IVF) center.