PROMOTION OF CHEMICAL CARCINOGENESIS AND P53 EXPRESSION BY REDUCTION OF SUPEROXIDE DISMUTASE ACTIVITY IN THE LUNG OF RAT IN V

ＰＲＯＭＯＴＩＯＮＯＦＣＨＥＭＩＣＡＬＣＡＲＣＩＮＯＧＥＮＥＳＩＳＡＮＤＰ５３ＥＸＰＲＥＳＳＩＯＮＢＹＲＥＤＵＣＴＩＯＮＯＦＳＵＰＥＲＯＸＩＤＥＤＩＳＭＵＴＡＳＥＡＣＴＩＶＩＴＹＩＮＴＨＥＬＵＮＧＯＦＲＡＴＩＮＶＩＶＯ￥ＹｕＬｕｎｙｉｎ；喻伦银；Ｂｉ...     

DIFFERENTIAL EXPRESSION AND RESPONSE OF GROWTH FACTORS IN DIFFERENT METASTATIC VARIANTS OF HUMANPULMONARY GIANT CELL CARCINOMA

ＤＩＦＦＥＲＥＮＴＩＡＬＥＸＰＲＥＳＳＩＯＮＡＮＤＲＥＳＰＯＮＳＥＯＦＧＲＯＷＴＨＦＡＣＴＯＲＳＩＮＤＩＦＦＥＲＥＮＴＭＥＴＡＳＴＡＴＩＣＶＡＲＩＡＮＴＳＯＦＨＵＭＡＮＰＵＬＭＯＮＡＲＹＧＩＡＮＴＣＥＬＬＣＡＲＣＩＮＯＭＡＺｅｎｇＬｉｎｇｆａｎｇ曾灵...     

CONSTRUCTION AND EXPRESSION OF THE REPLICATION-DEFI-CIENT ADENONIRUS VECTOR OF HUMAN GM-CSF

ＣＯＮＳＴＲＵＣＴＩＯＮＡＮＤＥＸＰＲＥＳＳＩＯＮＯＦＴＨＥＲＥＰＬＩＣＡＴＩＯＮＤＥＦＩＣＩＥＮＴＡＤＥＮＯＮＩＲＵＳＶＥＣＴＯＲＯＦＨＵＭＡＮＧＭＣＳＦＺｈａｎｇＷｅｉｐｉｎｇ章卫平ＣａｏＸｕｅｔａ曹雪涛ＴａｏＱｕｎ陶群Ｈｉｒｏｆｕｍ...     

EXPRESSION OF ONCOGENES DURING INDUCED DIFFERENTIATION OF HUMAN HEPATOCARCINOMA CELL LINE

ＥＸＰＲＥＳＳＩＯＮＯＦＯＮＣＯＧＥＮＥＳＤＵＲＩＮＧＩＮＤＵＣＥＤＤＩＦＦＥＲＥＮＴＩＡＴＩＯＮＯＦＨＵＭＡＮＨＥＰＡＴＯＣＡＲＣＩＮＯＭＡＣＥＬＬＬＩＮＥＣｈａｉＸｉｙｕｎ柴希运ＣｈｅｎＨｕｉｌｉ陈惠黎（ＤｅｐａｒｔｍｅｎｔｏｆＢｉｏｃｈｅｍｉｓ...     

ANTITUMOR EFFECT OF GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR(GM-CSF)-GENE ENCODED VACCINIA MELANOMA ONCOLYSATE AND ITS IMMUNOLOGICAL MECHANISMS

ＡＮＴＩＴＵＭＯＲＥＦＦＥＣＴＯＦＧＲＡＮＵＬＯＣＹＴＥＭＡＣＲＯＰＨＡＧＥＣＯＬＯＮＹＳＴＩＭＵＬＡＴＩＮＧＦＡＣＴＯＲ（ＧＭＣＳＦ）ＧＥＮＥＥＮＣＯＤＥＤＶＡＣＣＩＮＩＡＭＥＬＡＮＯＭＡＯＮＣＯＬＹＳＡＴＥＡＮＤＩＴＳＩＭＭＵＮＯＬＯＧＩ...     

ADYNAMIC STUDY OF THE CYTOTOXICEFFECTS OF HYPERTHERMIA COMBINED WITH CIS－DIAMINE DICHLOROLPLATINUM（DDP） ON HUMAN GASTRIC CANC

ＡＤＹＮＡＭＩＣＳＴＵＤＹＯＦＴＨＥＣＹＴＯＴＯＸＩＣＥＦＦＥＣＴＳＯＦＨＹＰＥＲＴＨＥＲＭＩＡＣＯＭＢＩＮＥＤＷＩＴＨＣＩＳ－ＤＩＡＭＩＮＥＤＩＣＨＬＯＲＯＬＰＬＡＴＩＮＵＭ（ＤＤＰ）ＯＮＨＵＭＡＮＧＡＳＴＲＩＣＣＡＮＣＥＲＣＥＬＬＬＩＮＥＳＭＫＮ...     

EFFECT OF ASCORBIC ACID ON DNA SYNTHESIS,INTRACELLULAR ACCUMULATION OF ADM AND ADM RESISTANCE OF TUMOR CELL LINES

ＥＦＦＥＣＴＯＦＡＳＣＯＲＢＩＣＡＣＩＤＯＮＤＮＡＳＹＮＴＨＥＳＩＳ，ＩＮＴＲＡＣＥＬＬＵＬＡＲＡＣＣＵＭＵＬＡＴＩＯＮＯＦＡＤＭＡＮＤＡＤＭＲＥＳＩＳＴＡＮＣＥＯＦＴＵＭＯＲＣＥＬＬＬＩＮＥＳＸｉｅＺｕｏｆｕ谢佐福ＬｉｎＸｉａｎｄｏｎｇ林贤东Ｚｈｏ...     

ENZYMO－ROCKET ELECTROPHORETIC ASSAY AND CROSSED AFFINITY ENZYMOIMMUNOELECTROPHORESIS AND ITS APLICATION IN DIAGNOSIS OF PLIMA

ＥＮＺＹＭＯ－ＲＯＣＫＥＴＥＬＥＣＴＲＯＰＨＯＲＥＴＩＣＡＳＳＡＹＡＮＤ　ＣＲＯＳＳＥＤＡＦＦＩＮＩＴＹＥＮＺＹＭＯＩＭＭＵＮＯＥＬＥＣＴＲＯＰＨＯＲＥＳＩＳＡＮＤＩＴＳ　ＡＰＬＩＣＡＴＩＯＮＩＮＤＩＡＧＮＯＳＩＳＯＦＰＬＩＭＡＲＹ　ＬＩＶＥＲＣＡＮ...     

THE EFFECT OF ACTIVE COMPONENTS OF LYCIUM BARBARUM AND GARLIC（LB－GO）ON THE SYNTHESIS OF DNA AND ULTRASTRUCTURE OF U_（14） CERV

ＴＨＥＥＦＦＥＣＴＯＦＡＣＴＩＶＥＣＯＭＰＯＮＥＮＴＳＯＦＬＹＣＩＵＭＢＡＲＢＡＲＵＭＡＮＤＧＡＲＬＩＣ（ＬＢ－ＧＯ）ＯＮＴＨＥＳＹＮＴＨＥＳＩＳＯＦＤＮＡＡＮＤＵＬＴＲＡＳＴＲＵＣＴＵＲＥＯＦＵ_（１４）ＣＥＲＶＩＸＣＡＮＣＥＲＣＥＬＬＳＩＮＭＩＣ?..     

GST-π EXPRESSION IN TRANSFORMED CELLS BY TRANSFECTING OF DNA ISOLATED FROM HUMAN FETAL LUNG TISSUES TREATED WITH CARCINOGENS

ＧＳＴπＥＸＰＲＥＳＳＩＯＮＩＮＴＲＡＮＳＦＯＲＭＥＤＣＥＬＬＳＢＹＴＲＡＮＳＦＥＣＴＩＮＧＯＦＤＮＡＩＳＯＬＡＴＥＤＦＲＯＭＨＵＭＡＮＦＥＴＡＬＬＵＮＧＴＩＳＳＵＥＳＴＲＥＡＴＥＤＷＩＴＨＣＡＲＣＩＮＯＧＥＮＳＹａｏＤｅｎｇｇａｏ姚登高ＨｕＧｕ...     

Imaging hemodynamics

Microvascular permeability is a pharmacologic indicator of tumor response to therapy, and it is expected that this biomarker will evolve into a clinical surrogate endpoint and be integrated into protocols for determining patient response to antiangiogenic or antivascular therapies. This review discusses the physiological context of vessel permeability in an imaging setting, how it is affected by active and passive transport mechanisms, and how it is described mathematically for both theoretical and complex dynamic microvessel membranes. Many research groups have established dynamic-enhanced imaging protocols for estimating this important parameter. This review discusses those imaging modalities, the advantages and disadvantages of each, and how they compare in terms of their ability to deliver information about therapy-associated changes in microvessel permeability in humans. Finally, this review discusses future directions and improvements needed in these areas.     

Imaging the liver

Imaging of the liver is undertaken for the detection and characterization of suspected primary or secondary neoplasms, prior to planning a surgery or chemotherapy pump placement, for assessing treatment response, for evaluating biliary pathology, and for screening for liver neoplasms in high-risk groups. In this article, we review the advantages and disadvantages of various imaging modalities in the evaluation of the liver and formulate guidelines for the imaging of common clinical indications. A brief review of imaging findings in focal and diffuse liver disease is also presented.     

EORTC Imaging Group

Imaging data have the potential to provide information on disease profiling pertaining to diagnosis, prognosis, selection of therapy, monitoring of response to therapy and pharmacokinetic information of drugs. Selection of the most appropriate imaging modality for a specific task will be vital for diagnosis, stratification, treatment response or treatment efficacy, toxicity assessment, and treatment outcome measures (progression-free survival). The EORTC Imaging Group was formed to establish and maintain the scientific and clinical value of advanced imaging in EORTC clinical trials. The group focuses on the development of specific analytical and review procedures as well as quality control procedures, in the context of clinical trials conducted by the EORTC groups.