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钻孔冲洗引流术是目前普遍认可的治疗慢性硬膜下血肿(chronic subdural hematoma,CSDH)的首选方法,具有简单有效、损伤小等优点,但也可发生多种并发症。我院1992年~2003年应用钻孔冲洗引流治疗CSDH 122例,死亡1例,出现急性硬膜外血肿1例,余120例无并发症治愈。作者认为术中适宜调整钻孔位置是预防CSDH钻孔冲洗引流术后并发症的关键。  相似文献   

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Background

It is widely believed that trepanation prior to modern surgical hygiene was dangerous because of surgical infection, especially in the hospital. There has been a wide variability in the success and risks of different historical studies

Purpose

To obtain a more accurate assessment of the risks of post-operative infection following 18th-century cranial trauma and to note what factors were of prognostic significance.

Material and methods

Seven 18th-century texts on head injury are reviewed and analyzed.

Results

Infection was the commonest cause of death (in over 60 % of patients) in five series but not in the other two. Hospital admission did not appear to be a major factor influencing mortality from infection. Delayed infection was the indication for patient referral and trepanation in more than two patients in two series. In one series, the patients were helped by the procedure, in the other they were not. The reasons for the difference are discussed. The most striking finding was that patients treated in rural areas had a much better prognosis.

Conclusions

The risks of suffering a surgical infection following head injury and trepanation are multifactorial. Admission to hospital seems to have been less risky than has been previously thought. It seems that the greatest risk factor for a lethal infection for these patients was living in an urban environment.  相似文献   

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Shafer  Audrey MD 《Anesthesiology》1995,83(6):1331-1342
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Morton's original definition of a sentinel node as the first lymph node to receive afferent lymphatic drainage from a primary tumor reflects the concept of stepwise spread of cancer through the lymphatic system. Several new definitions have been developed, based on surgical anatomy and on the technique that is used to find the node. The various definitions of a sentinel node are critically analyzed. Breast cancer surgeons use three different definitions of a false-negative sentinel node biopsy. The best definition appears to be based on the assumption that the procedure is truly positive if either the sentinel node or a suspicious node that is not radioactive or blue contains metastatic disease.  相似文献   

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More hospitalised patients with diarrhoea than patients without diarrhoea were underweight for age. In a retrospective survey of patients hospitalised more than once with either diarrhoea or bronchopneumonia, the patients with diarrhoea were found to have a greater decrease in weight for age at the time of the second admission than the patients with bronchopneumonia. The malnutrition associated with diarrhoea is due to a number of factors, including decreased intake, extra losses and malabsorption of nutrients. Patients on marginal food intakes may be unable to make up lost ground after diarrhoeal episodes and become malnourished. A brief survey of health professionals' attitudes suggested a tendency to overlook the nutritional component in the management of diarrhoea. Nutritional rehabilitation during and after episodes of diarrhoea ought to receive more emphasis in teaching and practice.  相似文献   

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Elevated phosphate (P) levels are seen in advanced renal failure and, together with dysregulated calcium, parathyroid hormone and vitamin D levels, contribute to the complex of chronic kidney disease–mineral and bone disease (CKD-MBD). Converging evidence from in vitro, clinical and epidemiological studies suggest that increased P is associated with vascular calcification and mortality. When vessels are exposed to high P conditions in vitro, they develop apoptosis, convert to bone-like cells and develop extensive calcification. Clinical studies in children on dialysis show that high P is associated with increased vessel wall thickness, arterial stiffness and coronary calcification. Epidemiological studies in adult dialysis patients demonstrate a significant and independent association between raised P and mortality. Importantly, raised P is associated with cardiovascular changes even in pre-dialysis CKD, and also in subjects with normal renal function but high P. All P binders can effectively reduce serum P, and this decrease is linked to improved survival. Raised serum P triggers the release of fibroblast growth factor 23 (FGF-23), which has the beneficial effect of increasing P excretion in early CKD, but is increased several 1,000-fold in dialysis, and may be an independent cardiovascular risk factor. Both FGF-23 and its co-receptor Klotho may have direct effects on the vasculature leading to calcification. Fascinatingly, disturbances in FGF-23–Klotho and raised P have also been associated with premature aging. These data suggest that high P levels have adverse vascular effects and that maintaining the serum P levels in the normal range reduces cardiovascular risk and mortality.  相似文献   

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