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1.
Sangam Shah Apil Pokhrel Rajan Chamlagain Yagya Raj Adhikari Bipin Kandel Roman Dhital Basanta Sharma Paudel Sutap Yadav 《Clinical Case Reports》2021,9(10)
This case demonstrates pneumothorax as a consequence of COVID‐19 and emphasizes the significance of follow‐up of the COVID‐19 patients. 相似文献
2.
Mhd Baraa Habib Ibrahim Mohammad Obeidat Khaled Ali Mohamed Abdelrazek Mouhand F. H. Mohamed 《Clinical Case Reports》2021,9(11)
Although pneumothorax is a well‐known complication of COVID‐19 pneumonia especially in patients requiring mechanical ventilation, bronchopleural fistula causing persistent pneumothorax in sole COVID‐19 pneumonia is extremely rare. In this case, we illustrate that bronchopleural fistula can be found in COVID‐19 pneumonia, even with no risk factors nor mechanical ventilation administration. 相似文献
3.
Fateen Ata Zohaib Yousaf Rana Farsakoury Adeel Ahmad Khan Abdullah Arshad Maya Omran Dore Chikkahanasoge Ananthegowda Mohamad Khatib Talat Saeed Chughtai 《Clinical Case Reports》2022,10(5)
Primary spontaneous tension pneumothorax (STP) is a rare and life‐threatening condition. We report a case of COVID‐19‐pneumonia patient who developed STP as a complication. He had a prolonged hospital stay and was ultimately discharged asymptomatic. A systematic literature search was performed to review studies (N=12) reporting STP in the setting of COVID‐19. 相似文献
4.
During the COVID‐19 pandemic, we should not forget about chronic, underlying and important diseases, especially diseases that cause immune system deficiency, of which TB is one and may be missed. Also, we should pay attention to the past medical history of the patients and their drug‐drug interactions during the treatment period of COVID‐19. Our main clinical message is that diseases such as TB, which weaken the immune system, may predispose a person to COVID‐19 infection and COVID‐19 may exacerbate TB and it’s mortality. On the other hand, diseases that target the lung tissue such as TB and COVID‐19, may have synergistic effects and increase mortality (for a patient whose lung capacity is reduced due to TB, superimposed COVID‐19 can worsen the situation). In addition, it may be necessary to take more serious considerations for COVID‐19 in low socio‐economy countries, such as Afghanistan, where TB is more prevalent 相似文献
5.
6.
Wenxue Dong Xu Yang Jing Li Zhiying Zhang Lijun Liu Zhipeng Zhao Longli Kang 《Journal of clinical laboratory analysis》2022,36(1)
BackgroundCoronavirus disease 2019 (COVID‐19) has had a devastating impact on public health services worldwide. Currently, there are no standard remedies or therapies for COVID‐19. it is important to identify and diagnose COVID‐19 to control the spread. But clinical symptoms of COVID‐19 are very similar to those of other respiratory viruses.ResultsAs a result, the diagnosis of COVID‐19 relies heavily on detecting pathogens. We established a bunch of triplex new TaqMan real‐time PCR assays. Three sets of primers and probes (targeting the ORF1ab, N, and E genes, respectively) are poorly consistent with other human coronaviruses and the human influenza virus. The sensitivity of established PCR assays notices as few as 100 copies per PCR of the ORF1ab, N, and E genes. Meanwhile, standard curves concluded from constant PCR reaction all showed glorious linear correlations between Ct values and the polymer loading copy variety (correlation coefficient (R2) of ORF1ab, N, and E genes is 0.996, 0.991, and 0.998, respectively). Surveillance of RNA‐based pseudovirus demonstrated that they were identified to be positive with respect to SARS‐CoV‐2 and that established PCR assays are achievable.ConclusionThe assays established provide a smaller reaction volume for diagnosing COVID‐19. 相似文献
7.
Maryam Koupaei Negar Shadab Mehr Mohamad Hosein Mohamadi Arezoo Asadi Sajjad Abbasimoghaddam Amirhosein Shekartabar Mohsen Heidary Fazlollah Shokri 《Journal of clinical laboratory analysis》2022,36(5)
IntroductionSince COVID‐19 outbreak, various studies mentioned the occurrence of neurological disorders. Of these, encephalitis is known as a critical neurological complication in COVID‐19 patients. Numerous case reports and case series have found encephalitis in relation to COVID‐19, which have not been systematically reviewed. This study aims to evaluate the clinical symptoms, diagnosis, treatment, and outcome of COVID‐19‐associated encephalitis.MethodsWe used the Pubmed/Medline, Embase, and Web of Science databases to search for reports on COVID‐19‐associated encephalitis from January 1, 2019, to March 7, 2021. The irrelevant studies were excluded based on screening and further evaluation. Then, the information relating diagnosis, treatment, clinical manifestations, comorbidities, and outcome was extracted and evaluated.ResultsFrom 4455 initial studies, 45 articles met our criteria and were selected for further evaluation. Included publications reported an overall number of 53 COVID‐19‐related encephalitis cases. MRI showed hyperintensity of brain regions including white matter (44.68%), temporal lobe (17.02%), and thalamus (12.76%). Also, brain CT scan revealed the hypodensity of the white matter (17.14%) and cerebral hemorrhages/hemorrhagic foci (11.42%) as the most frequent findings. The IV methylprednisolone/oral prednisone (36.11%), IV immunoglobulin (27.77%), and acyclovir (16.66%) were more preferred for COVID‐19 patients with encephalitis. From the 46 patients, 13 (28.26%) patients were died in the hospital.ConclusionIn this systematic review, characteristics of COVID‐19‐associated encephalitis including clinical symptoms, diagnosis, treatment, and outcome were described. COVID‐19‐associated encephalitis can accompany with other neurological symptoms and involve different brain. Although majority of encephalitis condition are reversible, but it can lead to life‐threatening status. Therefore, further investigation of COVID‐19‐associated encephalitis is required. 相似文献
8.
Roham Sarmadian Reza Ghasemikhah Hossein Sarmadian Mahmood Khosravi Saeed Hassani 《Clinical Case Reports》2022,10(7)
We describe splenic infarction (SI), an infrequent condition, in an 82‐year‐old COVID‐19 patient with chronic atrial fibrillation (AF). COVID‐19 may cause thrombosis, and AF is a predisposing factor for splenic infarction. Suspicion of SI may be warranted in COVID‐19 patients with abdominal pain, especially if a predisposing factor exists. 相似文献
9.
Meizhu Chen Changli Tu Cuiyan Tan Xiaobin Zheng Fengfei Sun Yingjian Liang Honglei Shi Jian Wu Yiying Huang Zhenguo Wang Kongqiu Wang Minmin Lin Weiming Wu Hong Zhou Jing Liu Jin Huang 《Clinical and translational allergy》2021,11(7)
BackgroundCOVID‐19 is a highly contagious respiratory disease caused by the SARS‐CoV‐2 virus. Patients with severe disease have a high fatality rate and face a huge medical burden due to the need for invasive mechanical ventilation. Hypoxic respiratory failure is the major cause of death in these patients. There are currently no specific anti‐SARS‐CoV‐2 drugs, and the effect of corticosteroids is still controversial.MethodsThe clinical data of 102 COVID‐19 patients, including 27 patients with severe disease, were analyzed. The serum levels of total IgE and anti‐SARS‐CoV‐2 specific IgE were compared in healthy controls and COVID‐19 patients, changes in the level of anti‐SARS‐CoV‐2 specific IgE and clinical response to methylprednisolone (MP) treatment were analyzed, and the effect of high‐dose/short‐term MP therapy for patients with critical illness and respiratory failure was determined.ResultsCOVID‐19 patients had elevated serum levels of anti‐SARS‐CoV‐2 specific IgE, and patients with severe disease, especially critical illness, had even higher levels. Application of short‐term/high‐dose MP significantly reduced the level of these IgE antibodies and also blocked the progression of hypoxic respiratory failure. Hypoxic respiratory failure in patients with COVID‐19 is related to pulmonary hypersensitivity.ConclusionsHypersensitivity in the lungs is responsible for acute respiratory failure in COVID‐19 patients. Application of high‐dose/short‐term MP appears to be an effective life‐saving method for COVID‐19 patients who have hypoxic respiratory failure. 相似文献
10.
The COVID‐19 gold standard assessment tool remained the RT‐PCR of upper respiratory tract specimen extracted by the nasopharyngeal swab. A positive result would decrease through a three‐week course and eventually be undetectable. The maximum duration of viral shedding is 83 days. Besides, COVID‐19 RT‐PCR remained positive for 74 days in a patient suffering from lymphoma. In this study, we have presented a 56‐year‐old male patient, a known case of lymphoma since 2015, who experienced many episodes of chemotherapy with a five‐month positive RT‐PCR COVID‐19 laboratory test and finally was intubated and then died of opportunistic pulmonary infections. COVID‐19 patients with concurrent lymphoma failed to remove the virus thoroughly, despite providing appropriate treatment regimens. 相似文献
11.
Rajab Mardani Mehrnoush namavar Elham ghorbi Zabihollah Shoja Fatemeh Zali Hooman Kaghazian Mohammad Reza Aghasadeghi Seyed Amir Sadeghi Shahram Sabeti Ilad Alavi Darazam Nayebali Ahmadi Seyed Dawood MousaviNasab 《Journal of clinical laboratory analysis》2022,36(1)
ObjectiveMost patients infected with the novel coronavirus (SARS‐CoV‐2), as the causative agent of COVID‐19 disease, show mild symptoms, but some of them develop severe illness. The purpose of this study was to analyze the blood markers of COVID‐19 patients and to investigate the correlation between serum inflammatory cytokines and the disease severity.MethodsIn this prospective cross‐sectional study, 50 patients with COVID‐19 and 20 patients without COVID‐19 were enrolled. According to ICU admission criteria, patients were divided into two groups of non‐severe and severe. Differences in the serum levels of C‐reactive protein (CRP), IL‐6, and TNF‐α, as well as erythrocyte sedimentation rate (ESR), lymphocytes (LYM) count, and neutrophils (NEU) count between the two groups were determined and analyzed.ResultsOut of the 50 patients with COVID‐19, 14 were diagnosed as severe cases. There was no significant difference between the two groups of COVID‐19 patients in terms of gender and age. Blood tests of COVID‐19 patients showed a significant decrease and increase in NEU and LYM counts, respectively. There were significant differences in the serum levels of IL‐6, TNF‐α, and CRP between the severe and non‐severe groups, which were higher in the severe group.Also, there was a significant correlation between the disease severity and CRP with ESR (r = 0.79), CRP with IL‐6 (r = 0.74), LYM with NEU (r = −0.97), and ESR with TNF‐α (r = 0.7).ConclusionThe findings of this study, as the first study in Iran, suggest that the levels of IL‐6, TNF‐α, ESR, and CRP could be used to predict the severity of COVID‐19 disease. 相似文献
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Zamelina Angela Razafindrasoa Kiady Ravahatra Harison Michel Tiaray Anjara Mihaja Nandimbiniaina Finaritra Princy Parfait Andriamahenina Sonia Marcelle Razafimpihanina Diamondra Ombanjanahary Andriarimanga Jocelyn Robert Rakotomizao Joëlson Lovaniaina Rakotoson Rondro Nirina Raharimanana 《Clinical Case Reports》2022,10(5)
Aspergillosis superinfections have been reported as acute complications of COVID‐19. We report a rare case of combined chronic necrotizing pulmonary aspergillosis, aspergilloma, and fibrosing aspergillosis in a 31‐year‐old woman with a history of COVID‐19. Chest scan remains an important imaging method assisting in the diagnosis and management of post‐COVID‐19 patients. 相似文献
13.
Yoshifumi Amari Satoshi Morimoto Takashi Teranishi Mai Ohata Atsushi Takeshita Hiroshi Hirano Hitoshi Kobayashi 《Clinical Case Reports》2022,10(7)
This article reports a clinical and histopathological perspective which noted not only COVID‐19 pneumonia but also exacerbation of chronic renal failure potentially caused by thrombus in the kidney, possibly COVID‐19‐related lesions. The accumulation of autopsy cases will elucidate the pathogenesis of COVID‐19 and aid in the development of effective therapeutics. 相似文献
14.
Etedal Ahmed A. Ibrahim Khabab Abbasher Hussien Mohamed Ahmed Elmuntasir Taha Salah Mohammed Eltahier Abdalla Omer 《Clinical Case Reports》2021,9(8)
COVID‐19 is a mysterious disease presented in different ways, so we have to deal with each patient nowadays thoroughly, including COVID‐19 testing as routine test. The Case report discusses the rare finding of COVID‐19 in CSF of GBS patient. 相似文献
15.
Zeinab Aryanian Kamran Balighi Parvaneh Hatami Nasim Mazloumi Tootoonchi Azadeh Goodarzi Zeinab Mohseni Afshar 《Clinical Case Reports》2022,10(4)
Although the presence of morphea following COVID‐19 has been rarely reported, the development of its generalized form following COVID‐19 vaccination has not been reported yet. Here, we reported the first case of generalized morphea following COVID‐19 vaccination and another similar case following SARS‐Cov‐2 infection. Other etiologic factors were also dealt with. 相似文献
16.
Masoumeh Farahani Kiarash Azadi Maryam Hashemnejad Arash Agoushi Matineh Nirouei 《Clinical Case Reports》2021,9(12)
Coronavirus disease (COVID‐19) is an infectious disease. In this study, we report a 28‐year‐old pregnant woman who had a postpartum seizure with a background of HELLP syndrome and a proven COVID‐19 infection. Her child survived, and at 12‐week postpartum, all maternal COVID‐19–related symptoms vanished, and she was cured. 相似文献
17.
Zhe Zhu Yayun Yang Lingyan Fan Shuyuan Ye Kehong Lou Xin Hua Zuoan Huang Qiaoyun Shi Guosheng Gao 《Journal of clinical laboratory analysis》2021,35(8)
BackgroundDyslipidemia has been observed in patients with coronavirus disease 2019 (COVID‐19). This study aimed to investigate blood lipid profiles in patients with COVID‐19 and to explore their predictive values for COVID‐19 severity.MethodsA total of 142 consecutive patients with COVID‐19 were included in this single‐center retrospective study. Blood lipid profile characteristics were investigated in patients with COVID‐19 in comparison with 77 age‐ and gender‐matched healthy subjects, their predictive values for COVID‐19 severity were analyzed by using multivariable logistic regression analysis, and their prediction efficiencies were evaluated by using receiver operator characteristic (ROC) curves.ResultsThere were 125 and 17 cases in the non‐severe and severe groups, respectively. Total cholesterol (TC), high‐density lipoprotein cholesterol (HDL‐C), low‐density lipoprotein cholesterol (LDL‐C), and apolipoprotein A1 (ApoA1) gradually decreased across the groups in the following order: healthy controls, non‐severe group, and severe group. ApoA1 was identified as an independent risk factor for COVID‐19 severity (adjusted odds ratio [OR]: 0.865, 95% confidence interval [CI]: 0.800–0.935, p < 0.001), along with interleukin‐6 (IL‐6) (adjusted OR: 1.097, 95% CI: 1.034–1.165, p = 0.002). ApoA1 exhibited the highest area under the ROC curve (AUC) among all single markers (AUC: 0.896, 95% CI: 0.834–0.941); moreover, the risk model established using ApoA1 and IL‐6 enhanced prediction efficiency (AUC: 0.977, 95% CI: 0.932–0.995).ConclusionBlood lipid profiles in patients with COVID‐19 are quite abnormal compared with those in healthy subjects, especially in severe cases. Serum ApoA1 may represent a good indicator for predicting the severity of COVID‐19. 相似文献
18.
Takatoshi Enomoto Takayuki Shiroyama Haruhiko Hirata Saori Amiya Yuichi Adachi Takayuki Niitsu Yoshimi Noda Reina Hara Kiyoharu Fukushima Yasuhiko Suga Kotaro Miyake Shohei Koyama Kota Iwahori Izumi Nagatomo Natsuko Tokuhira Akinori Uchiyama Yoshito Takeda Atsushi Kumanogoh 《Clinical Case Reports》2022,10(2)
This is the first report of COVID‐19 in a human T‐cell lymphotropic virus type‐1 (HTLV‐1) carrier. HTLV‐1 infection can cause immune dysfunction even in asymptomatic carriers. This case highlights the need for guidance on management of COVID‐19‐HTLV‐1 coinfection, specifically on the appropriate use of corticosteroid treatment while considering secondary infection. 相似文献
19.
Left ventricular thrombosis and endogenous endophthalmitis in the setting of COVID‐19: A case report
Mohammad Javad Zibaeenezhad Alireza Moaref Firoozeh Abtahi Mohsen Moghadami Mohammad Karim Johari Ali Ardekani Mohammad Keshavarz 《Clinical Case Reports》2022,10(5)
Aside from typical pneumonia, the coronavirus disease 2019 (COVID‐19) has shown several extra‐pulmonary manifestations. This study was done on a 66‐year‐old male patient who concomitantly had endogenous endophthalmitis and left ventricular thrombosis one month after being hospitalized due to COVID‐19. 相似文献
20.
Oliver Pfaar Eckard Hamelmann Ludger Klimek Christian Taube Christian Vogelberg Martin Wagenmann Thomas Werfel Margitta Worm 《Clinical and translational allergy》2022,12(3)
BackgroundWhen the coronavirus pandemic 2019 (COVID‐19) emerged, concerns were also raised regarding the safety of allergen immunotherapy (AIT). The German Society for Allergology and Clinical Immunology (DGAKI) conducted a survey to collect real‐world data on the daily routine of administering subcutaneous AIT (SCIT) and sublingual AIT (SLIT) during the COVID‐19 pandemic.MethodsA web‐based retrospective survey using the online platform survio with 26 standardized questions was used to survey physicians treating allergic patients during the pandemic.ResultsThree hundred and forty‐five physicians who regularly offer and perform AIT in German‐speaking countries responded to the questions. 70.4% of the respondents stated that they regularly initiated and dosed up SCIT for inhalant allergies (41.4% venom‐SCIT, 73.6% SLIT), and 85.2% of the respondents stated that they continued SCIT for inhalant allergies during the maintenance phase in a regular way (59.1% venom‐SCIT, 90.4% SLIT) in healthy patients without current symptoms indicating an infection with COVID‐19. With regard to tolerability, there was no evidence for increased occurrence of adverse events in patients without current symptoms of COVID‐19 infection during the pandemic.ConclusionsThis retrospective study demonstrated adherence to national and international position papers of AIT during the COVID‐19 pandemic in German‐speaking countries. Besides, the survey has confirmed a good tolerability of AIT for both SCIT and SLIT. 相似文献