血管覆膜支架置入治疗胸主动脉夹层动脉瘤

目的:介绍覆膜支架血管内置入治疗胸主动脉夹层动脉瘤(TADA)的初步经验。方法:本组4例Debakey B型胸主动脉夹层动脉瘤,经CT或MR增强检查确诊。经股动脉置入覆膜支架,封堵胸主动脉破裂口,置入后造影检查证实疗效,术后随访采用彩超或增强CT检查。结果:4例患者共成功置入7个支架,1例术后支架远端出现内漏,6个月后内漏自行封闭;1例并发的腹主动脉瘤随访2个月无变化;随访2~18个月,所有患者内膜破裂口封闭,胸降主动脉和腹主动脉真腔扩大,假腔内血栓形成,支架位置、形态正常。结论:覆膜支架血管内置入治疗胸主动脉夹层动脉瘤的近期疗效满意。     

内支架置入术治疗胸腹主动脉瘤的临床评价

目的：探讨胸腹主动脉瘤的ESG治疗临床疗效。方法：对10例患者分别行CTA、MRA、DSA检查和ESG治疗，其中Stanford B型夹层动脉瘤6例，真性腹主动脉瘤2例，肾动脉开口以下腹主动脉瘤2例（行分体式支架），所有病例均采用带膜支架。结果：8例行一体式支架腔内隔绝术，2例行分体式支架腔内隔绝术，均获成功。顺利植入，术后造影提示动脉瘤消失．无内漏发生。患者症状完全消失，全部患者在随访期间均未出现术前症状，未见相关并发症。结论：应用ESG治疗胸腹主动脉瘤安全、有效、创伤小、术后恢复快，长期疗效尚待进一步观察。     

血管腔内隔绝术治疗降主动脉夹层动脉瘤

目的：探讨血管腔内隔绝术治疗降主动脉夹层动脉瘤的技术方法和疗效。方法：对10例降主动脉夹层动脉瘤患者的临床资料进行分析,其中2例为DeBakeyШa型,8例为DeBakeyШb型。1例夹层动脉瘤仅累及腹主动脉,合并真性动脉瘤。影像学资料显示全组有3例在不同部位有2个以上撕裂口。结果：1例腹主动脉混合型动脉瘤按腹主动脉瘤腔内隔绝术进行,2例将人工带膜支架封闭左锁骨下动脉口,另7例均顺利进行主动脉腔内隔绝术。随访2~16个月,全部病例均存活。结论：血管腔内置入带膜支架型人工血管是治疗主动脉夹层动脉瘤的简便、安全、有效的方法。     

动脉覆膜支架腔内隔绝治疗Stanford A型主动脉夹层临床效果

【摘要】 目的 探讨应用主动脉覆膜支架腔内隔绝术治疗Stanford A型主动脉夹层的临床效果。方法 回顾性分析2016年6月至2018年10月在湖南中医药大学第一附属医院接受主动脉弓部开窗支架技术全腔内隔绝升主动脉、主动脉弓及降主动脉近段治疗的14例Stanford A型主动脉夹层患者临床资料。观察术后随访1年临床疗效。结果 14例患者均顺利完成手术。术后1年5例治疗效果理想。术后早期死亡1例,支架近端再发夹层4例,发生Ⅰ型、Ⅱ型内漏各1例,Ⅲ型2例。 结论 对于不能外科修复的A型主动脉夹层,可谨慎选择主动脉弓部开窗支架技术行全腔内修复治疗,但须根据患者自身情况和血管病变特点严格把握适应证。     

经皮开窗术治疗主动脉夹层引起的缺血

目的 评价经皮开窗术治疗主动脉夹层引起的内脏及下肢缺血。方法 6例主动夹层并发内脏及下肢缺血患者行经皮开窗术，所有患者皆是Stanford B型夹层，累及的血管有肾动脉（3条）、肠系膜动脉（1条）和下肢动脉（6条）。4例行单纯经皮开窗术，1例行开窗及左肾动脉支架置入治疗，1例行开窗及腹主动脉和双侧髂总动脉支架置入治疗。1例患者于开窗后1个月行支架移植物复合体（stent—graft）腔内隔绝术。结果 所有6例患者血管重建均成功，其中4例缺血症状消失，2例明显减轻。随访4～12个月，平均7．6个月，1例患者术后3个月死于主动脉破裂出血，余5例仍存活。无严重的手术相关并发症。结论 经皮开窗术或经皮开窗结合支架置入是1种安全、有效的治疗主动脉夹层引起的内脏及下肢缺血的方法。     

Stanford B型胸主动脉夹层动脉瘤合并肾缺血的诊治(附3例报告)

为探讨合并肾缺血的StanfordB型胸主动脉夹层动脉瘤的诊断和处理 ,分析 1996年 1月至 2 0 0 0年 4月收治的StanfordB型胸主动脉夹层动脉瘤 2 9例 ,其中合并肾缺血 3例 ,为急性期 2例 ,慢性期 1例。急性期 1例发病后第 3天死亡 ,另 1例同时合并肾缺血和双下肢缺血 ,经夹层隔膜开窗术缓解 ;慢性期 1例经腔内隔绝术治愈夹层后肾缺血自行缓解。提示合并肾缺血的StanfordB型胸主动脉夹层动脉姑息性转流手术有助于缓解症状 ,提高生存率 ;对于慢性StanfordB型胸主动脉夹层动脉瘤合并肾缺血的患者 ,腔内隔绝术在治愈夹层动脉瘤的同时恢复了真腔供血 ,肾缺血可同时治愈     

MSCTA在Debakey Ⅲ型主动脉夹层动脉瘤中的应用

目的探讨多层螺旋CT血管造影在Debakey Ⅲ型主动脉夹层动脉瘤诊断中的应用价值及其与DSA的比较研究.方法研究56例拟行腔内带膜内支架置入术的Debaley Ⅲ型主动脉夹层动脉瘤患者的MSCTA表现,分别测量第一内膜片裂口位置、大小,左锁骨下动脉开口平面的主动脉最大径等参数,并与DSA检查结果进行比较.结果MSCTA与DSA对Debakey Ⅲ型主动脉夹层动脉瘤的诊断符合率达92%,MSCTA还可发现主动脉之外的其他疾病.MSCTA与DSA对内膜片第一裂口的大小及位置的测量无明显差异;对左锁骨下动脉开口平面的主动脉最大径的测量有明显差异,DSA的数值小于MSCTA.结论MSCTA可以明确诊断Debakey Ⅲ型主动脉夹层动脉瘤,同时还可发现主动脉之外的其他疾病.MSCTA对主动脉夹层动脉瘤的各个参数的准确测量可帮助和指导腔内带膜内支架置入手术,可作为Debakey Ⅲ型主动脉夹层动脉瘤诊断及腔内带膜内支架置入术的术前评估中首选的影像学检查方法.     

应用国产覆膜支架治疗Stanford B型主动脉夹层动脉瘤

目的:评价应用国产覆膜支架治疗B型主动脉夹层动脉瘤的安全性及临床疗效.方法:自2005 - 05～2009 - 12对38例Stanford B型主动脉夹层动脉瘤实施了腔内隔绝术.其中男29例,女9例;年龄(54±12)岁.经CT增强扫描或磁共振成像(MRJ)确诊.切开左或右股动脉置入覆膜支架,封堵胸主动脉破裂口,置入后造影检查证实疗效,随访行CT或MRI检查.结果:支架置入全部成功,术后即刻造影36例无内漏,2例见少量内漏.降主动脉及腹主动脉真腔均明显扩大,远端降主动脉及分支供血均有不同程度改善.住院期间及随访1年内无患者死亡,发生主动脉腔内隔绝术后综合征3例.结论:应用国产覆膜支架腔内隔绝治疗B型主动脉夹层动脉瘤是一种操作简便、安全、成功率高、并发症少,疗效可靠的介入方法.     

主动脉夹层或瘤的腔内隔绝术临床评价(附23例报道)

目的:评价应用腔内血管支架治疗腹主动脉瘤的优点。方法:对24例患者行DSA和带膜血管腔内支架植入隔绝手术治疗,其中Stanford B型夹层动脉瘤19例,真性腹主动脉瘤4例,假性腹主动脉瘤1例。所有病例均采用TALENTTM带膜支架移植物系统。术后对所有患者行螺旋CT随访。结果:除1例因胸主动脉夹层破口位于左锁骨下动脉开口处,无法放置腔内血管支架而行开胸手术外,余23例均顺利放入,术后患者症状完全消失,全部患者在随访期间均未出现术前症状,未见相关并发症。结论:应用带膜支架治疗胸主动脉Stanford B型夹层、真性和假性腹主动脉瘤,其效果较单纯开放式手术效果好且不良反应小,值得在临床上推广和应用。     

带膜支架治疗Stanford B型胸主动脉夹层的经验探讨

目的:探讨Stanford B型胸主动脉夹层(TAD)腔内隔绝术一些经验.方法:回顾性分析我院2002年～2005年全麻下行腔内隔绝术的36例Stanford B型胸主动脉夹层患者的资料.结果:所有患者均成功实行了带膜支架腔内隔绝术,未出现死亡现象,内漏9例,右股动脉切开处内膜撕裂3例.结论:带膜支架置入术治疗Stanford B型胸主动脉夹层是一种安全有效的方法,但术中术后并发症的预防是成功的关键.     

Knee injury and Osteoarthritis Outcome Score (KOOS) - validation of a Swedish version

The Knee injury and Osteoarthritis Outcome Score (KOOS) is a self-administered instrument measuring outcome after knee injury at impairment, disability, and handicap level in five subscales. Reliability, validity, and responsiveness of a Swedish version was assessed in 142 patients who underwent arthroscopy because of injury to the menisci, anterior cruciate ligament, or cartilage of the knee. The clinimetric properties were found to be good and comparable to the American version of the KOOS. Comparison to the Short Form-36 and the Lysholm knee scoring scale revealed expected correlations and construct validity. Item by item, symptoms and functional limitations were compared between diagnostic groups. High responsiveness was found three months after arthroscopic partial meniscectomy for all subscales but Activities of Daily Living.     

The acutely limping child

Acute limping may be the result of multiple pathologies in children. The differential diagnosis varies based on the age of the child. Irrespective of age, the initial imaging work-up includes AP and frog leg radiographs of the pelvis and ultrasound; MRI may sometimes be helpful. In children less than 3 years, infections and trauma are most frequent. MRI is the imaging modality of choice when osteomyelitis is clinically suspected. Between the ages of 3 and 10 years, transient synovitis of the hip and Legg-Calvé-Perthes disease are main considerations but infection, inflammation and focal bony lesions are also considered. In children over 10 years, slipped capital femoral epiphysis also is considered.     

Do Balance Board Training Programs Reduce the Risk of Ankle Sprains in Athletes?

Introduction Ankle sprains are the most common musculo-skeletal injury that occurs in athletes,particularly in sports that require jumping and landing on one foot such as soccer,and basketball(1-4).These injuries often result in significant time loss from participation,long-term disability,and have a major impact on health care costs and resources(5-8).     

High Intensity Interval Training:New Insights

KEY POINTS ·High-intensity interval training(HIT)is characterized by repeated sessions of relatively brief，intermittent exercise.often performed with an“a11 out”effort or at an intensity close to that which elicits peak oxygen uptake(i.e.，≥90%of VO2 peak).     

Endovascular management of carotid-cavernous fistulas

Objective To investigate endovascular treatment of traumatic direct carotid-cavernous fistulas （CCF） and their complications such as pseudoaneurysms. Methods： Over a five-year period, 22 patients with traumatic direct CCFs were treated endovascularly in our institution. Thirteen patients were treated once with the result of CCF occluded, 8 twice and 1 three times. Treatment modalities included balloon occlusion of the CCF, sacrifice of the ipsilateral internal carotid artery with detachable balloon, coll embolization of the cavernous sinus and secondary pseudoaneurysms, and covered-stem management of the pseudoaneurysms. Results All the direct CCFs were successfully managed endovascularly. Four patients developed a pseudoaneurysm after the occlusion of the CCF with an incidence of pseudoaneurysm formation of 18.2% （4/22）. A total number of 8 patients experienced permanent occlusion of the ICA with a rate of ICA occlusion reaching 36.4% （8/22）. Followed up through telephone consultation from 6 months to 5 years, all did well with no recurrence of CCF symptoms and signs. Conclusion Traumatic direct CCFs can be successfully managed with endovascular means. The pseudoaneurysms secondary to the occlusion of the CCFs can be occluded with stent-assisted coiling and implantation of covered stents.     

Developmental validation of the PowerPlex(®) ESI 16 and PowerPlex(®) ESI 17 Systems: STR multiplexes for the new European standard

In response to the ENFSI and EDNAP groups’ call for new STR multiplexes for Europe, Promega^® developed a suite of four new DNA profiling kits. This paper describes the developmental validation study performed on the PowerPlex^® ESI 16 (European Standard Investigator 16) and the PowerPlex^® ESI 17 Systems. The PowerPlex^® ESI 16 System combines the 11 loci compatible with the UK National DNA Database^®, contained within the AmpFlSTR^® SGM Plus^® PCR Amplification Kit, with five additional loci: D2S441, D10S1248, D22S1045, D1S1656 and D12S391. The multiplex was designed to reduce the amplicon size of the loci found in the AmpFlSTR^® SGM Plus^® kit. This design facilitates increased robustness and amplification success for the loci used in the national DNA databases created in many countries, when analyzing degraded DNA samples. The PowerPlex^® ESI 17 System amplifies the same loci as the PowerPlex^® ESI 16 System, but with the addition of a primer pair for the SE33 locus. Tests were designed to address the developmental validation guidelines issued by the Scientific Working Group on DNA Analysis Methods (SWGDAM), and those of the DNA Advisory Board (DAB). Samples processed include DNA mixtures, PCR reactions spiked with inhibitors, a sensitivity series, and 306 United Kingdom donor samples to determine concordance with data generated with the AmpFlSTR^® SGM Plus^® kit. Allele frequencies from 242 white Caucasian samples collected in the United Kingdom are also presented. The PowerPlex^® ESI 16 and ESI 17 Systems are robust and sensitive tools, suitable for the analysis of forensic DNA samples. Full profiles were routinely observed with 62.5 pg of a fully heterozygous single source DNA template. This high level of sensitivity was found to impact on mixture analyses, where 54–86% of unique minor contributor alleles were routinely observed in a 1:19 mixture ratio. Improved sensitivity combined with the robustness afforded by smaller amplicons has substantially improved the quantity of data obtained from degraded samples, and the improved chemistry confers exceptional tolerance to high levels of laboratory prepared inhibitors.     

Bronchial stump fistula :treatment with covered retrievable hinged metallic stents-preliminary clinical experience

Objective To evaluate the preliminaily clinical efficacy and retrievability of a retrievable hinged covered metallic stent in the treatment of the bronchial stump fistula （BSF）. Methods Between April 2003 and March 2005, 8 patients with bronchial stump fistula after pneumonectomy or lobectomy were treated with two types （A and B） of retrievable hinged covered metallic stents. Type A stent was placed in 6 patients and type B in 2 under fluoroscopic guidance. The stent was removed with a retrieval set when BSF was healed or complications occurred. Results Stent placement in the bronchial tree was technically successful in all patients, without procedure-related complications. Immediate closure of the BSF was achieved in all patients after the procedure. Stents were removed from all patients but one. Removal of the stents was difficult in two patients due to tissue hyperplasia. Patients were followed up for 6 - 21 months. Placement of the stents remained stable in all patients except one due to severe cough. Permanent closure of BSF was achieved in 7 （87.5%） of 8 patients. Conclusion Use of a retrievable hinged covered expandable metallic stent is a simple, safe, and effective procedure for closure of the BSF. Retrieval of the stent seems to be feasible. （J Intervent Radiol, 2007, 16： 253-257）     

Prevalence and severity of hip and groin pain in sub‐elite male football: a cross‐sectional cohort study of 695 players

The purpose of this study was twofold: (a) to investigate the prevalence of hip and groin pain in sub‐elite male adult football in Denmark and (b) to explore the association between prevalence and duration of hip and groin pain in the previous season with the Copenhagen Hip and Groin Outcome Score (HAGOS) in the beginning of the new season. In total 695 respondents from 40 teams (Division 1–4) were included. Players completed in the beginning of the new season (July–Sept 2011) a self‐reported paper questionnaire on hip and/or groin pain during the previous season and HAGOS. In total 49% (95% CI: 45–52%) reported hip and/or groin pain during the previous season. Of these, 31% (95% CI: 26–36%) reported pain for >6 weeks. Players with the longest duration of pain during the previous season had the lowest HAGOS scores, when assessed at the beginning of the new season, P < 0.001. This study documents that half of sub‐elite male adult football players report pain in the hip and/or groin during a football season. The football players with the longest duration of pain in previous season displayed the lowest HAGOS scores in the beginning of the new season.