Surgical treatment of pancreatic pseudocysts

The surgical treatment of pancreatic pseudocysts (PC) has a less important role now that endoscopic and radiologic intervention can effectively treat PC. Surgery may be needed to correct the underlying cause--usually an obstructed or disrupted pancreatic duct.     

假性胰腺囊肿的外科手术治疗

目的对假性胰腺囊肿的外科手术治疗方式和效果进行评价。方法回顾性分析了我院1990年1月至2003年10月68例假性胰腺囊肿行手术治疗的方式、效果及并发症。结果行外科手术治疗的病人人数占同期假性胰腺囊肿治疗病人的48．9％(68／139)。手术方式包括：外引流术9例，死亡率11．1％(1／9)；囊肿胃吻合20例，术后消化道出血的发生率为35％(7／20)，死亡率5％(1／20)；囊肿空肠Roux-en-Y吻合23例，术后消化道出血的发生率为13％(3／23)，死亡率4．3％o(1/23)；假性囊肿切除14例；囊肿十二指肠吻合1例；胰十二指肠切除1例。结论虽然目前假性胰腺囊肿的治疗可有多种选择，但仍有许多病人需要外科手术治疗。手术治疗应尽可能行内引流术，其中囊肿胃吻合术是一种简单合理的内引流术式，应作为首先。对于难以排除恶性的假性囊肿，应尽量手术切除。     

胰腺巨大假性囊肿27例的外科治疗

目的 探讨巨大胰腺假性囊肿的临床特点,并对各种外科治疗方法进行评价.方法 对1991年2月至2008年2月收治的27例巨大胰腺假性囊肿(长径>10cm)的临床资料进行回顾性分析.结果 27例巨大胰腺假性囊肿约占同期全部胰腺假性囊肿的20.9%;病因分类:急性胰腺炎所致占51.9%,胰腺外伤和手术所致占33.3%,慢性胰腺炎所致占11.1%;病程小于6周者占绝大多数(21/27);30%患者出现上消化道梗阻(8/27);影像学上虽然囊肿巨大,但均为单房囊肿;ERCP检查发现多数囊肿与胰管相通(9/11).手术方式包括囊肿外引流术9例,均失败,改行其他内引流术.囊肿胃吻合术10例,1例失败,改行囊肿空肠引流术,ERCP胰腺导管囊肿内支架引流术2例,1例失败,改行囊肿空肠引流术,囊肿空肠Roux-en-Y吻合术17例(其中11例为采用其他手术方式治疗失败者).所有患者均临床治愈.结论 胰腺巨大假性囊肿多数出现胰管解剖学改变,外科治疗时机和适应证有别于一般性胰腺假性囊肿.     

Surgical methods in the treatment of pancreatic pseudocysts

The results of treatment of 209 patients suffering pancreatic pseudocysts are adduced. The pseudocyst maturity degree determines the method of treatment choice. Optimal combination of conservative and the puncture methods constitute the main principle of treatment of acute pancreatic pseudocysts.     

Surgical management of pancreatic pseudocysts.

Pancreatic pseudocyst is a complication of pancreatitis or pancreatic trauma. A review of the experience with surgical treatment of pseudocyst of the pancreas at the University of Iowa was carried out. Pancreatitis associated with alcoholism accounted for a smaller percentage of the pseudocysts than is usually reported and reflects the nature of the population. Internal drainage of the pseudocyst obviates the development of pancreatic fistula which is often associated with external drainage; however, the mortality for each method of drainage was comparable.     

Surgical treatment of pancreatic pseudocysts in the 2000's--laparoscopic approach

A pseudocyst presents as a cystic cavity bound to the pancreas by inflammatory tissue. Typically the wall of a pancreatic pseudocyst lacks an epithelial lining, and the cyst contains pancreatic juice or amylase-rich fluid. Today the mostly used definitions make a difference between peripancreatic fluid collections, pseudocysts after acute and chronic pancreatitis and pancreatic abscess as in the Atlanta classification system for acute pancreatitis. Distinction between pseudocyst and acute fluid collection leads to a better understanding of the natural history of peripancreatic fluid collections and facilitates the progress of the treatment of these two separate entities even though they are a part of a continuous pathological process. The presence of a well-defined wall composed of granulation or fibrous tissue is what distinguishes a pseudocyst from an acute fluid collection. A pseudocyst is usually rich in pancreatic enzymes and is most often sterile. Formation of a pseudocyst requires usually 4 or more weeks (many clinicians state six) from the onset of acute pancreatitis. The differentiation in the Atlanta classification between acute and chronic pseudocyst is important, but it invite to confusion. It is important to note that in the classification the terms "acute" and "chronic" refers to the pancreatitis behind the pseudocyst and not to the mode of symptomatology of the pseudocyst itself. This means that an acute pseudocyst may have be known for months, whereas a chronic pseudocyst in the next patient has been documented only a week or two.     

Surgical treatment of pancreatic pseudocysts. Analysis of 119 cases.

A review was made of the hospital records of 119 patients with pancreatic pseudocysts. Alcoholism, biliary disease and abdominal trauma were the most common antecedent conditions. Abdominal pain was the most frequent symptom, and abdominal tenderness or mass were the most common physical findings. Abdominal echography and contrast study of the upper gastrointestinal tract were diagnostic in 90% of the patients examined. X-rays of the chest, colon, and biliary tract revealed pathology in 30--40% of the patients. Compared to patients with uncomplicated pseudocyst, patients who were acutely ill at the time of external drainage had twice the incidence of postoperative complications. Each subgroup experienced similar, high rates of postoperative death and pseudocyst recurrence. Both groups of patients treated by internal drainage had lower rates of postoperative morbidity, mortality, and pseudocyst recurrence than patients with uncomplicated pseudocysts undergoing external drainage. External drainage should be used in all patients with immature pseudocysts and in critically ill patients with mature pseudocysts not juxtaposed to a portion of the upper gastrointestinal tract. Internal drainage is a safer and more effective procedure in most other patients with mature pseudocysts, irrespective of the clinical status of the patient.     

Surgical treatment of pancreatic pseudocysts. A review of 42 cases

21 years' experience of operated pancreatic pseudocysts is reviewed. The number of patients was 42, with mean age of 50 +/- 5 years. Thirteen patients (31%) were alcoholic. In 6/42 cases (14%) pancreatic carcinoma was considered the reason for pseudocyst formation. In 30 patients an internal and in 11 an external drainage was created. Operative mortality occurred in 3 patients (7%). External drainage was effected in patients with complicated pseudocyst. The complication rate in this group was 6/11 (55%) and in the internal drainage group 7/30 (23%). Internal drainage is a safe and effective procedure in patients with a mature pseudocyst wall. External drainage should be used in patients critically ill or with an immature pseudocyst wall.     

Laparoscopic treatment of pancreatic pseudocysts

Background A multicentric study was performed to evaluate the clinical results after laparoscopic treatment of pancreatic pseudocysts (PP). Methods We collected the data of 17 patients presenting with PP and operated on by laparoscopy between 1996 and 2001. There were nine men and eight women with a median age of 42 years (range 30–72). In 15 patients the PP developed after acute pancreatitis and the median delay between the acute onset and surgery was 7 months (range: 2–24). In two patients the PP was associated with chronic pancreatitis. All the patients has a single PP with a median diameter of 9 cm (range: 5–20). Results According to the location of the PP, a cystogastrostomy was performed in 10 patients and a cystojejunostomy in seven patients. The median operative time was 100 min (range: 80–300). Laparoscopic PP surgery was completed suscessfully in 16 patients and the median size of the cystoenterostomy was 3 cm (range: 2–5). Necrotic debris was present within the PP in 11 patients. The median, postoperative hospital stay way 6 days (range: 4–24). No mortality and no immediate morbidity were recorded. However, two patients were readmitted within the first 3 postoperative weeks because of secondary PP infection. The first patient had an early closure of cystograstrostomy and was treated by endoscopic placement of a stent. The second represented with a right retrocolic abscess after cystojejunostomy and was treated by percutaneous drainage. One patient was lost for follow-up 2 months after surgery. The others had regular clinical and radiological controls. With a median follow-up of 12 months (range: 6–36), no recurrence of PP was observed. Conclusions The laparoscopic treatment of PP was associated with a low postoperative complication rate and an effective permanent result. That approach avoided some difficulties, particularly bleeding that is classically linked with endoscopic internal drainage.     

Endoscopic treatment of pancreatic pseudocysts

Background  

This study aimed to assess the effectiveness of therapeutic endoscopy in the treatment of pancreatic pseudocysts, and to define factors limiting endoscopic therapy.     

Puncture-drainage treatment of pancreatic postnecrotic pseudocysts

From 1989 to 1998 we treated 94 patients with pancreatic pseudocysts. 55 patients underwent laparotomy (external drainage of the cyst, sequestrectomy). 14.5% patients of this group presented with postoperative complications, mean hospital stay was 36 days. During 1997-1998 we performed US-controlled punctures and drainage in 37 patients with pancreatic pseudocysts. This method was efficient in 83.7% of the cases without sequesters in the cystic cavity. Use of this method allowed to decrease the percentage of complications and lethality rate, and reduce the mean hospital stay by 47.2%.     

Surgical decision-making in the treatment of pancreatic pseudocysts. Internal versus external drainage

One hundred patients with documented pancreatic pseudocysts who underwent surgical drainage are reported on. Accurate assessment of the size and location of the pseudocyst using ultrasonography, endoscopic retrograde cholangiopancreatography, angiography, and upper gastrointestinal roentgenography is essential. After diagnosis, the next 4 to 7 weeks is a critical period, after which surgical intervention becomes mandatory if the cyst has not resolved. This period between diagnosis and operation is hazardous and demands close clinical follow-up. When oepration is required, the preferred procedure continues to be internal drainage because it is associated with less morbidity and a lower mortality. However, external drainage appears to be a suitable second choice. Fewer than 10 per cent of the patients in this series who underwent external drainage developed fistulas, and the overall rate of late morbidity was acceptable.     

胰腺假性囊肿38例诊治分析

目的: 探讨胰腺假性囊肿的诊断方法和治疗效果.方法: 回顾分析38例胰腺假性囊肿的临床资料.结果: 保守治疗6例,外引流5例,内引流26例,囊肿切除1例.无死亡,2年随访无复发.结论: B超和CT扫描是主要的诊断方法,ERCP可了解胰管病变和囊肿关系.大多数患者需外科手术,囊肿空肠Roux-Y 吻合内引流术是主要的手术方式.