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1.
昼夜节律神经元的神经生物学   总被引:6,自引:0,他引:6  
Whydobirdssinginthemorningandfrogscallatnight?Whydomostheartattacksstrikebeforedawn,whileasthamaticattacksoccuraftersunset?Whydowefeelthatthedark,shortdaysofwinteraredrearyandthelong,sunnydaysofsummerarecheerful?Theanswertothesequestionsliesinunderstand…  相似文献   

2.
Multipledatahavesuggestedthattherenin angiotensinsystem (RAS )contributestothepathogenesisofatherosclerosis Acommonfeatureinallstagesofatherogenesisistheparticipationoftheinflammationprocessinthevesselwall 1 Thetranscriptionfactor,nuclearfactor kappaB (NF …  相似文献   

3.
About 30 %~ 50 %ofpatientswithatherosclerosislackidentifiedriskfactors (suchashypertension ,smoking ,hypercholesterolemia ,anddiabetes) .Ithasbeenpostulatedthatadditionalfactorspredisposingtoatherosclerosismayexist.Discoveryofsuchfactors ,alongwiththeiraccom pan…  相似文献   

4.
Ithasbeenreportedthattheclassicalmodelofthedominanceofthelefthemisphereofhumanbrainisincorrectbecauseitisinaccuratetosaythatwhichhemisphereisdominant Thehemispheresareasymmetricalintheirfunction Inthisstudywetriedtofindouttheactivatedareasandtoconfirm…  相似文献   

5.
Tumorigenesisproceedsthroughanaccumulationofspecificgeneticalterations Recentstudieshavefocusednotonlyonthederegulationofcellproductionbutalsoontheinhabitationofcellloss Thisstudyassessedtherelationshipbetweenapoptoticstatusandbiologicalbehaviorduring…  相似文献   

6.
受体介导的细胞内信息传递系统在烟雾吸入性损伤肺组织的变化及机制的研究Studyonthechangesandmechanismsofreceptormediatedintracellularmessengertransductionsystemsin...  相似文献   

7.
Lymphangiomyomatosis   总被引:1,自引:0,他引:1  
Lymphangiomyomatosis (LAM )isaprogressivediseaseaffectingwomenofchildbearingage Itismicroscopicallycharacterizedbyabnormalsmoothmuscleproliferationthatcausesgradualobstructionofsmallairways ,lymphaticsandvasculature Theproliferationeventuallyresultsinach…  相似文献   

8.
Itisdifficulttoblockthetransmissionofschistosomiasisbychemotherapy ,thereforemanyresearchershavebeeninterestedinthestudyofvaccineofschistosomiasis Thestudyofvaccineofschistosomiasiswasmostlyfocusedonanti infectionimmunity ,butthemosthopefulcandidatemole…  相似文献   

9.
Woundhealingistheprocessbywhichcellproliferationisstringentlycontrolled ProgressionthroughtheG1phaseandinitiationofthecellcycleinmammaliancellsdependsonthebalanceofinteractionbetweencellcyclepositiveregulatorssuchascyclinD1,cyclinE ,cyclin dependentkina…  相似文献   

10.
Chroniccutaneousulcersrepresentamajorhealth careproblemwithconsiderablesocioeconomicimpact 1,2Traditionally,localtreatmentofchroniccutaneousulcersconsistsofconstantlocalwoundcare ,surgery ,skingrafting,debridementandvascularreconstruction Chroniculcersmayi…  相似文献   

11.
TGF-β1基因转染修饰人退变腰椎间盘髓核细胞   总被引:1,自引:0,他引:1  
Degenerationofthelumbardiscaffectsthemechanicalpropertiesofthespineandisrelatedtoclinicallowbackdisorders Thelimitedavailabletechnologygenerallyishighlyinvasiveandusuallydiscectomyisinvolved ,whichoftencompromisesthestructuralintegrityofthespine Longte…  相似文献   

12.
Theuterinecavitycommunicateswiththeexternalenvironmentandisthereforeexposedtoforeignantigens Itdoesnothaveacomplexstructureoflymphnodesandretainsthecharacteristicsofaprimitivesurfaceepithelia 1Previousstudieshavedemonstratedthepresenceoflymphocytesint…  相似文献   

13.
Carcinoidtumorshavebeenfoundinvariousorgansofthebody,especiallyinthegastrointestinalandrespiratorytracts Carcinoidtumoroftheepididymisisespeciallyrare Wedescribehereacaseofprimarycarcinoidtumoroftheepididymisthatwasdetectedbyaccidentinapatientwhounder…  相似文献   

14.
Aninterestingremarkintheprefaceofalinguis ticstextbooksays ,“Don’trunafterthreethingsintheworld ,women ,buses,andlinguistics ,becausetherearealwaysnewonescomingupfor youtocatch .Itis ,unfortunately ,onlytootruetothemodernlinguisticstudies ,whichinvolvetheSeco…  相似文献   

15.
人肺癌转移动物模型建立及其生物学特性的研究   总被引:3,自引:2,他引:1  
人肺癌转移动物模型建立及其生物学特性的研究Astudyonestablishmentofmetastaticmodelsforhumanlungcarcinomainmiceandtheirbiologicalcharacteristics魏泓史景...  相似文献   

16.
Thenumberofpatientswithlungcancerisincreasingrapidly,cancersinvolvingthelungarebesttreatedbycomplete,enblocresection.Whentheyextendintotheleftatrium,lungcancersarerecognizedtobeinoperable.Introductionofthetechniquesofcardiovascularsurgeryhasmadepossibl…  相似文献   

17.
几种理化因素诱导的细胞微核形成及其自动化检测的研究Thestudiesonthemicronucleusformationinducedbyseveralchemicalandphysicalfactorsandtheirmicronucleusau...  相似文献   

18.
Role of p38 protein kinase in heat-induced Raw cells apoptosis   总被引:5,自引:1,他引:4  
Aftercellsareexposedtoastressingagent,celldeathcanbeobservedasapoptosis,necrosisandmitoticdeathApoptosisorphysiologiccelldeath,isundergeneticcontrolandischaracterizedmorphologicallybycellshrinkage,marginationofchromatinandnuclearfragmentationGenomicDNA…  相似文献   

19.
Objective Tostudythepreventiveeffectsofsingleuseofazathioprineanditscombinationwithmethylprednisoloneonchroniccerebralvasospasm(CVS) Methods Acaninemodelofthe“doublesubarachnoidhemorrhage (SAH)”wasestablishedtostudytheangiogramcharacteristicsofchronicC…  相似文献   

20.
Theprevalenceratesoftineapedisandonychomycosisaredeterminedbyage ,predisposingfactor,socialclass ,occupation ,climate ,livingenvironmentandfrequencyoftravel 1 Inspiteofimprovedpersonalhygieneandlivingenvironment,tineapedisandonychomycosiscontinuetospreada…  相似文献   

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