自身免疫性胰腺炎的诊治进展

自身免疫性胰腺炎(autoimmune pancreatitis, AIP)是一种特殊类型的慢性胰腺炎, 以胰腺弥漫性肿大及胰管不规则狭窄、淋巴细胞及浆细胞组织浸润、血清免疫球蛋白4(immunoglobulin G4, IgG4)水平升高、伴或不伴有胰外器官受累为特征。AIP起病隐匿, 症状和体征缺乏特异性, 容易与胰腺癌、胆管癌相混淆。目前临床医生对该疾病认识不足, 缺乏相关诊疗经验, 部分患者因误诊而接受了不必要的手术治疗。本文对AIP的诊治进展作一综述, 以期提高临床医师对该疾病的认识。     

脊柱脊髓疾病的治疗现状和进展

近年来,随着人们对脊柱脊髓疾病认识的提高,以及脊柱固定技术的成熟、术中CT和导航系统的问世和介入技术的发展,颅颈交界处畸形、脊柱退行性病变和脊髓血管畸形等脊柱脊髓疾病的诊治方面取得了长足的进步.本文就上述几种疾病的治疗作一简短评述,仅反映作者的认识和体会,权作抛砖引玉,希望引起读者关注,并对此类疾病进一步研究、治疗.     

蒙药治疗脊柱外伤性截瘫临床初探

蒙医药是我国民族医药学中的一个重要组成部份。是蒙古族人民同疾病长期斗争中所总结的经验和智慧结晶,历史悠久,内容丰富。也是一门具有鲜明民族特点的民族医学科学。它不仅有着独特的理论体系,而且临床经验丰富,药量小,疗效好,经济简便,深受内蒙古自治区蒙汉民族的欢迎,继承和发扬这部份珍贵的民族医学遗产,无疑对丰富和发展我国医药学,为全国各族人民服务,有着十分重要意义。     

对结直肠癌病理的新认识

病理诊断具有确定疾病的性质进而决定治疗方案的关键作用,特别是在肿瘤诊断中,其重要性毋庸置疑.随着病理学的不断发展,人们对肿瘤病理学的认识也在不断深化.现就结直肠癌病理学的新进展、新观点作一概述.     

对结直肠癌病理的新认识

病理诊断具有确定疾病的性质进而决定治疗方案的关键作用,特别是在肿瘤诊断中,其重要性毋庸置疑.随着病理学的不断发展,人们对肿瘤病理学的认识也在不断深化.现就结直肠癌病理学的新进展、新观点作一概述.     

对结直肠癌病理的新认识

病理诊断具有确定疾病的性质进而决定治疗方案的关键作用,特别是在肿瘤诊断中,其重要性毋庸置疑.随着病理学的不断发展,人们对肿瘤病理学的认识也在不断深化.现就结直肠癌病理学的新进展、新观点作一概述.     

对结直肠癌病理的新认识

病理诊断具有确定疾病的性质进而决定治疗方案的关键作用,特别是在肿瘤诊断中,其重要性毋庸置疑.随着病理学的不断发展,人们对肿瘤病理学的认识也在不断深化.现就结直肠癌病理学的新进展、新观点作一概述.     

对结直肠癌病理的新认识

病理诊断具有确定疾病的性质进而决定治疗方案的关键作用,特别是在肿瘤诊断中,其重要性毋庸置疑.随着病理学的不断发展,人们对肿瘤病理学的认识也在不断深化.现就结直肠癌病理学的新进展、新观点作一概述.     

对结直肠癌病理的新认识

病理诊断具有确定疾病的性质进而决定治疗方案的关键作用,特别是在肿瘤诊断中,其重要性毋庸置疑.随着病理学的不断发展,人们对肿瘤病理学的认识也在不断深化.现就结直肠癌病理学的新进展、新观点作一概述.     

对结直肠癌病理的新认识

病理诊断具有确定疾病的性质进而决定治疗方案的关键作用,特别是在肿瘤诊断中,其重要性毋庸置疑.随着病理学的不断发展,人们对肿瘤病理学的认识也在不断深化.现就结直肠癌病理学的新进展、新观点作一概述.     

The effects and prospects of the integration of traditional Chinese medicine and Western medicine on andrology in China

Andrology has a long history in traditional Chinese medicine (TCM) discussions concerning andropathies, and documentation of relevant therapeutic methods abound in the ancient literature on TCM. Integrated treatment combining TCM and Western medicine has seen both broad and in-depth development, with formidable status in the field of modern andrology in China. This article attempts to demonstrate the unique advantage of integrated treatment in the therapy of andropathies through a review of the ancient literature on andrology in the field of TCM and on the integrative treatment of prostatic diseases, sexual dysfunction, male infertility and late-onset hypogonadism. There is a need for the advancement of a medical theory that integrates TCM and Western medicine practices to create a new therapeutic system with standardized therapeutic and evaluative protocols for diseases involving male sexual health.     

Andrology in China： current status and 10 years＇ progress

Andrology has a long history in traditional Chinese medicine. There are records of male sexual health, male sexual dysfunction and male infertility from over thousands of years ago. Modern andrology in China had a late start, with the Chinese Andrology Association founded in 1995. Within last decade, andrology in China has grown rapidly. In this review article, we summarized the progress of andrology in last 10 years and outlined the current status of Chinese andrology with a special focus on progress in male erectile dysfunction, prostate diseases, male infertility and male hormonal contraception.     

Impact of garlic feeding (Allium sativum) on male fertility

Many medicinal plants are designed to improve health but their mechanism of action remains not clear. Among these plants, garlic (Allium sativum) has attracted particular attention of modern medicine because of its widespread use for the prevention and treatment of some human diseases such as cardiovascular diseases and cancer. However, the impact of garlic on the male reproductive system has not been clearly defined. Some studies have reported that garlic improves male sexual function and has beneficial effect in the recovery of testicular functions. However, other authors have shown that this plant impairs testicular functions (such as inhibition of testosterone production) and has spermicidal effect on spermatozoa. In this review, we attempt to clarify the current ambiguity regarding the effects of garlic and its preparations on the male reproductive system.     

神阙灸疗法的临床应用进展

神阙灸是指运用艾灸熏烤神阙穴，是传统灸疗的一种特殊疗法，历史久远，在临床各科应用广 泛，疗效确切。为进一步推广神阙灸的临床应用，本文系统整理并分析了有关神阙穴、神阙灸在临床应用 和实验研究方面的相关文献，归纳总结神阙灸在临床上相关疾病的应用概况，以期为神阙灸在临床相关疾 病的治疗以及相关研究方面提供参考和借鉴。     

Role of identified noncoding RNA in erectile dysfunction

Erectile dysfunction (ED) is a common male sexual dysfunction and is closely related to many risk factors such as age, chronic diseases and mental disorder. Phosphodiesterase type 5 inhibitor (PDE5i) is recommended as the first-line medicine in therapy, but up to 35% of patients fail to this treatment. Unfortunately, the pathogenesis of ED is still poorly understood. Hence, it has reached the state that researchers should seek for new candidate biomarkers or therapeutic targets. Recent studies have reported that noncoding RNAs (ncRNAs) such as microRNAs (miRNAs) and long noncoding RNAs (lncRNAs) are involved in the pathogenesis process of ED, even in stem cell therapy. In this review, we aim to summarise the mechanisms and functions of identified ncRNAs that are associated with ED.     

穴位贴敷治疗原发性骨质疏松症的研究进展

原发性骨质疏松症是一种常见的慢性病,病发往往悄无声息,多数患者并发骨折后才能发觉。随着中医药近几十年的发展,有关防治原发性骨质疏松症的中医临床研究日趋丰富,为中医药抗骨质疏松症的疗效提供了有力证据,在内治法和外治法两个方面均取得了显著的疗效。中医外治法[1]具有见效快,副反应小等特点,且历史悠久,使用方便。本文所讨论的穴位敷贴法属于中医外治法的一种类型,随着穴位贴敷运用的发展,目前在临床上出现了各种制剂,如透皮吸收贴剂、透皮控释制剂等,其药物有效成分吸收率更高,疗效更佳,广泛运用于内科疾病如哮喘、便秘和失眠等,在防治骨质疏松方面同样具有较好的疗效,但在临床上得不到较高的重视,临床研究报道相对较少,本文参考近5年文献从中医理论出发对穴位敷贴防治骨质疏松症的机制、选穴和临床运用等方面进行归纳和总结。旨在方便为各位学者提供穴位敷贴防治方法的最新研究状况,提升对穴位敷贴法的认识,使之在临床上得到更好的运用。     

中药治疗勃起功能障碍的分子机制

勃起功能障碍(ED)是临床上男性的常见病和多发病,长期以来中药在我国ED治疗中具有重要地位,随着对勃起功能和ED发生机制的认识深入,目前已阐明部分中药治疗ED的作用机制,这对于中药的推广开发利用具有重要作用。     

Regenerative medicine as a new therapeutic strategy for lower urinary tract dysfunction

The use of regenerative medicine for the treatment of organic and functional disorders intractable to conventional treatment has increased worldwide. This innovative medical field might particularly hold promise for the treatment of life‐threatening diseases or healing of irreplaceable organs, such as the heart, liver and brain. Dysfunction of the urogenital tract and associated organs other than the kidney might not have immediate life‐threatening implications; furthermore, the effectiveness of alternative therapy, such as enterocystoplasty for bladder cancer, has been shown. Therefore, most physicians or scientists do not give much importance to these disorders. However, urological disease has increased in developed societies in recent years. Furthermore, medical costs have also escalated. Disorders of the lower urinary tract, such as urinary disturbance or incontinence, can lead to other complications, impairing quality of life and ultimately increasing short‐ and long‐term medical expenses. Regenerative medicine might hold potential solutions to these problems. Recent advances in urogenital regenerative medicine are reviewed in the present article, with particular reference to lower urinary tract reconstruction. The potential of regenerative medicine for the treatment of intractable lower urinary tract dysfunction compared with conventional treatment is also discussed.     

结直肠癌围手术期的“症病同治”策略探讨

结直肠癌是全球最常见恶性肿瘤之一,多数患者首诊为晚期,即使手术治疗,后面也存在放化疗不良反应及复发的风险,寻找更有效的治疗策略是提高治愈率与存活率的关键。全国老中医药专家学术经验继承工作指导老师陈志强教授首次提出“症病同治”的诊疗策略,临床发现应用“症病同治”治疗老年病及膀胱癌术后疗效满意。本文结合实践,对结直肠癌围手术期的“症病同治”策略进行探讨。     

“骨肉不相亲”理论指导下肌抑素在肌少-骨质疏松症中的机制探讨

随着人口老龄化的日益加剧,"肌少-骨质疏松症"(sarco-osteopenia)这类肌肉及骨协同退变的疾病日益增多,给社会带来巨大负担。中医很早就对肌骨协同退变疾病进行了记录,其中"骨肉不相亲"理论是中医学对肌骨协同退变病理机制的高度概括。近年研究发现,肌肉生长抑制素(Myostatin)由骨骼肌分泌,通过多条途径参与了骨骼肌和骨组织生长代谢的调节过程,可能成为肌骨之间调节的重要因子。笔者在"骨肉不相亲"理论的指导下,通过探究肌肉生长抑制素调控骨骼肌与骨代谢的机制,以期揭示肌少-骨质疏松症的病理机制,探索中医理论的现代医学实质,为该类疾病的防治提供新的思路。