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1.
Toshiya Endo Rieko Ozoe Mifumi Kubota Mahito Akiyama Shohachi Shimooka 《American journal of orthodontics and dentofacial orthopedics》2006,129(1):29-35
INTRODUCTION: The purpose of this retrospective study was to assess the prevalence and distribution of hypodontia in the permanent dentition, excluding the third molars, in a sample of Japanese orthodontic patients. METHODS: Orthopantomograms of 3358 Japanese orthodontic patients (1453 boys and 1905 girls) between the ages of 5 and 15 years were examined for evidence of hypodontia. RESULTS: The prevalence of hypodontia was 8.5% (7.5% for boys, 9.3% for girls) with no statistically significant difference between the sexes. The average number of missing teeth per child was 2.4 (2.5 for boys, 2.4 for girls). Most (76.3%) children with hypodontia were missing either 1 or 2 teeth (77.1% for boys, 75.7% for girls). The prevalence of advanced hypodontia was 10.1% (11.0% for boys, 9.7% for girls). The most commonly missing teeth were the mandibular second premolars, followed by the mandibular and maxillary lateral incisors, and the maxillary second premolars; minor differences in the order of prevalence existed among groups of children classified by the number of missing teeth. Symmetrical hypodontia was predominant, and the most commonly symmetrical hypodontia was mandibular second premolar agenesis. No consistent finding was obtained as to which jaw had more missing teeth. The distribution of missing teeth was similar between the right and left sides of the dental arches in each group of children. Anterior tooth agenesis was predominant in children with minor hypodontia, and posterior tooth agenesis increased with hypodontia severity. CONCLUSIONS: The distinct characteristic of hypodontia in the Japanese population compared with other populations was a higher prevalence of both advanced hypodontia and mandibular lateral incisor agenesis in children with minor hypodontia. 相似文献
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Axelsson S Bjørnland T Kjaer I Heiberg A Storhaug K 《Acta odontologica Scandinavica》2003,61(3):129-136
Williams syndrome is a rare congenital syndrome with distinctive craniofacial features, cardiovascular abnormalities, and behavior characteristics including mental retardation. The dental abnormalities have received scant attention in previous literature. The aim of this study was to describe dental characteristics in individuals with Williams syndrome. In a group of 41 individuals more than 10 years of age, 40.5% had agenesis of one or more permanent teeth and 11.9% had agenesis of 6 permanent teeth or more. The mesio-distal and labio-lingual dimensions of permanent tooth crowns were measured on 31 dental study casts from individuals older than 12 years. The mesio-distal and labio-lingual dimensions were significantly smaller compared with a reference sample. An analysis of tooth morphology was performed on the same dental study casts revealing altered tooth morphology. A high proportion of maxillary and mandibular incisors was tapered or screwdriver shaped. An evaluation of taurodontism on mandibular permanent molars was performed using a metric crown-body/root ratio. However, most of the molars rated as being taurodontic had short or extremely short total tooth lengths and could thus be rated taurodontic without meeting the classical definition. The results of this study indicate that although there is variation in dental development in individuals with Williams syndrome, agenesis of permanent teeth in combination with aberrations in tooth size and morphology may affect dental esthetics and complicate orthodontic and prosthodontic treatment. 相似文献
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Stavropoulos D Bartzela T Bronkhorst E Mohlin B Hagberg C 《European journal of oral sciences》2011,119(3):198-203
Dental agenesis may either occur as an isolated trait (non-syndromic) or as a component in a congenital syndrome. The aim of the present study was to identify the prevalence of dental agenesis for each type of tooth and to look for dental agenesis patterns in persons with Apert syndrome. Serial panoramic radiographs of 23 individuals (five male patients and 18 female patients) were examined. Third molars were excluded. The prevalence of agenesis for at least one tooth was 34.8%. Up to two missing teeth were found for individuals with Apert syndrome. Maxillary lateral incisors and mandibular second premolars were the most frequently missing teeth. Four different dental agenesis patterns of the entire dentition were identified by using the tooth agenesis code (TAC). Two patterns occurred more frequently, both of which were symmetrical. One involved the simultaneous absence of teeth 12 and 22, and the other showed agenesis of teeth 35 and 45. In conclusion, patients with Apert syndrome were found to exhibit a high prevalence of dental agenesis. All dental agenesis patterns in which more than one tooth was missing were symmetrical. 相似文献
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Prevalence and patterns of permanent tooth agenesis in individuals with Down syndrome: a meta‐analysis
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The aims of the present study were to evaluate the prevalence and patterns of permanent tooth agenesis in individuals with Down syndrome, using meta‐analysis methodology. Two independent investigators carried out a literature search to locate articles pertaining to permanent tooth agenesis in individuals with Down syndrome. The outcomes of interest were the prevalence and pattern of permanent tooth agenesis. Thirteen articles were selected for inclusion. The estimated overall prevalence of permanent tooth agenesis, excluding third molars, was 54.6% (95% CI: 44–66%). Considerable heterogeneity was present across the studies. Among subjects with tooth agenesis, approximately half had three or more missing teeth. The permanent teeth with the highest prevalence of agenesis were the maxillary lateral incisor (27%), mandibular second premolar (21%) and maxillary second premolar (18%). The single most commonly absent tooth, however, was the mandibular left second mandibular premolar (19.9%), followed by the maxillary left lateral incisor (19.4%). Little data describing specific tooth‐agenesis patterns were available. In conclusion, individuals with Down syndrome display high prevalence rates and severity of agenesis of permanent teeth. Proper and timely diagnosis of missing permanent teeth is thus necessary, to allow a more comprehensive long‐term treatment plan and a more favorable prognosis in these individuals. 相似文献
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Toshiya Endo Sugako Sanpei Akira Komatsuzaki Saori Endo Akiko Takakuwa Kenji Oka 《Odontology / the Society of the Nippon Dental University》2013,101(2):216-221
The aim of this study was to explore the patterns of tooth agenesis in Japanese orthodontic patients with bilateral agenesis of mandibular second premolars. A total of 80 Japanese orthodontic patients with 2 congenitally missing mandibular second premolars were selected as the subjects of this study (experimental group). Another 80 individuals without bilateral agenesis of mandibular second premolars were collected for comparison (control group). The 2 groups were matched with regard to sex. Radiographs, dental casts and records of medical and/or dental treatment were used to identify tooth agenesis. The Chi-square test, odds ratio, and test for equality were used to make statistical comparisons. The prevalence rates of other types of tooth agenesis were significantly higher in the experimental group than in the control group. The occurrence of agenesis of maxillary and mandibular lateral incisors and third molars, and maxillary second premolars was also significantly higher in the experimental group than in the control group. Significantly increased prevalence rates of symmetrical tooth agenesis, with third molars included, and oligodontia were observed in the experimental group. Japanese subjects with bilateral agenesis of mandibular second premolars are at significantly high risk of agenesis of other types of permanent teeth, symmetrical tooth agenesis and oligodontia. 相似文献
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dos Santos BM Ribeiro RR Stuani AS de Paula e Silva FW de Queiroz AM 《Brazilian dental journal》2006,17(3):249-254
This article reports the case of a Brazilian child diagnosed with Kabuki make-up syndrome (KMS), addressing the clinical features observed, with emphasis on the disease-specific oral and craniofacial manifestations. The patient had the distinctive KMS craniofacial appearance, mild delayed mental development, fingers with prominent fingertip pads and visual deficit. The dental findings included fusion of the left mandibular incisors (central and lateral), gemination of the right mandibular central incisor and congenital agenesis of the right mandibular lateral incisor, in the primary dentition, as well as absence of both permanent mandibular lateral incisors. Fusion and gemination have not been previously referred to as typical dental features in KMS. The detection of unique dental findings, such as missing teeth and dental anomalies of form in the primary dentition by means of clinical and radiographic examinations, might consist of a helpful diagnosis parameter in identifying children who may have milder forms of Kabuki syndrome. 相似文献
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目的 研究儿童口腔科门诊先天缺牙患者的临床特征和可能影响发病的因素。方法 对2014年1—12月于中国医科大学附属口腔医院儿童口腔科就诊的16 320例患者进行先天缺牙的临床调查,针对先天缺牙的部位、数目及可能影响发病的因素等进行分析。结果 326例患者确诊为先天缺牙,占调查患者人数的2.0 %。其中,多数牙缺失患者44例,平均缺牙数为(7.98 ± 2.98)颗;个别牙缺失患者282例,平均缺牙数为(2.09 ± 1.04)颗。多数牙缺失患者中具有家族遗传史者所占比例明显高于个别牙缺失患者。缺牙好发部位依次为下颌第二前磨牙、上颌第二前磨牙、上颌侧切牙、下颌中切牙、第一前磨牙、上颌尖牙。采用非条件Logistic回归对先天缺牙的可能影响因素进行分析,发现家族史是先天缺牙的危险因素(P < 0.01),而患者父母的文化程度、母亲受孕年龄、母亲妊娠期放射线接触史及是否为早产儿等因素,均不是先天缺牙的影响因素(P > 0.05)。结论 先天缺牙多为个别牙缺失,好发部位主要为下颌第二前磨牙;多数牙缺失可能与家族遗传密切相关。 相似文献
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??Objective To investigate the clinical characteristics and possible related factors of tooth agenesis in the patients in the pediatric dentistry. Methods A total of 16320 children?? who came to Pediatric Dentistry Clinic of Stomatology Hospital affiliated to China Medical University from January to December in 2014?? were examined. The number?? position and the influencing factors were analyzed. Results Totally 326 children were diagnosed with tooth agenesis?? accounting for 2.0%. Among these patients?? 44 were oligodontia with the average number of missing teeth at 7.98 ± 2.98?? 282 were hypodontia with the average number of missing teeth at 2.09 ± 1.04. The proportion of children with family history in oligodontia was significantly higher than that in hypodontia. Most of the missing teeth were located in the second mandibular premolar?? followed by the second maxillary premolar?? maxillary lateral incisor?? mandibular central incisors?? the first molar and maxillary cuspid. Influencing factors for tooth agenesis were analyzed by non-conditional Logistic regression. Family history was a risk factor for congenital missing teeth ??P < 0.01??. Parents' educational level?? pregnancy age?? history of radiation exposure during pregnancy and preterm birth were not the influencing factors for tooth agenesis ??P > 0.05??. Conclusion Hypodontia is the most common type of tooth agenesis and the second mandibular premolars are predominantly affected. Oligodontia might be closely relate to genetic factor. 相似文献
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OBJECTIVE: To investigate the radiographic development of permanent teeth in a group of children (66 females and 69 males, aged 3.08-15.02 years) with agenesis of one or more permanent teeth compared to a matched group. DESIGN: Tooth formation of all developing permanent teeth was assessed using Haavikko's method (1970) from dental panoramic tomographs. The difference between dental and chronological age was tested using a paired t-test. The correlation between the difference of dental and chronological age and severity of hypodontia was investigated using Spearman correlation test. In addition, radiographs of all children with only one single missing tooth in one quadrant and no more than two agenesis in total (N=59), were analyzed using the non-parametric Wilcoxon sign test, in order to investigate if the development of the teeth adjacent to the site of the agenesis was effected. RESULTS: Tooth formation in children with hypodontia was significantly delayed compared to the matched group (p<0.001). The mean difference was 1.51 years (S.D. 1.37 years). The severity of the hypodontia effected the magnitude of the delay (p<0.01). The teeth adjacent to the site of the agenesis were significantly delayed compared to the corresponding teeth in the matched group (p<0.01). CONCLUSION: These results confirm that the development of permanent teeth in children with hypodontia is different when compared with a matched group. 相似文献
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The prevalence of hypodontia in children with clefts, both inside and outside the cleft region, and the possible association between the side of the cleft and the side of the missing teeth were studied using radiographs of 278 patients with cleft lip, cleft palate, or both (158 boys and 120 girls), age 5 to 18 years (mean age 10.4 years). A hypodontia prevalence of 77% (excluding third molars) was found for the total cleft sample. This was significantly higher, both statistically and clinically, than the incidence of hypodontia reported for noncleft populations, and considerably higher than the prevalence reported in other studies of children with clefts. The maxillary permanent lateral incisors were the teeth most frequently missing on the cleft side (259 teeth) followed by the maxillary (47 teeth) and mandibular (23 teeth) second premolars, in both boys and girls. The teeth that were most often missing on the noncleft side were the maxillary second premolars (12 teeth), followed by the maxillary lateral incisors (10 teeth) and mandibular second premolars (6 teeth). Hypodontia of both the maxillary lateral incisors and second premolars was found more frequently on the left side, which also has a higher frequency of clefting. 相似文献
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Matern O Sauleau EA Tschill P Perrin-Schmitt F Grollemund B 《The Cleft palate-craniofacial journal》2012,49(3):e1-e5
Objective : Individuals with oral clefts exhibit considerably more dental anomalies than do individuals without clefts. Our aim was to evaluate the prevalence of tooth agenesis in a sample composed of 124 children (81 boys and 43 girls, mean age 12.5?years) with clefts registered with the Cleft Palate Center in Strasbourg (France). Design : Cleft types and dental agenesis were assessed by clinical and radiographic examination. Cleft types were divided into four groups according to the clinical extent of the cleft (cleft lip only [CL, 12.9%], cleft lip and alveolus [CLA, 4%], cleft lip and palate [CLP, 49.2%], and cleft palate only [CP, 33.9%]). Results : Of the subjects 63% had evidence of hypodontia: maxillary lateral incisors (54%) and upper and lower premolars (32%) were the most common missing teeth. The number of dental ageneses associated with CP (54%) and CLP (79%) was significantly higher than that with CL (33%). All these anomalies were found in proportionately higher frequencies as the severity of the cleft increased, and we found left side predominance for hypodontia (p < .01) irrespective of cleft sidedness. Conclusions : Both right-sided and left-sided clefts were more frequently correlated with left-sided dental agenesis. This left-sided prevalence suggests that common signaling malfunctions might be involved, both in dental development anomalies and cleft genesis. 相似文献
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Agenesis of teeth in a patient who also presents with a supernumerary tooth is one of the rare numerical anomalies in human dentition. Agenesis of third molars was shown to be associated with other missing permanent teeth. A review of literature on hypodontia including third molar agenesis, hyperdontia and a concomitant presence of these two conditions which is termed as hypohyperdontia is presented along with a case showing agenesis of three third molars, both mandibular central incisors and a midline supernumerary tooth. 相似文献
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Masamichi Ide Chihiro Kuriyama Chie Takeuchi Yutaka Takamizawa Sachiyo Takamizawa Takao Namba Tadafumi Tomohiro Yoshinobu Asada 《Pediatric Dental Journal》2011,21(1):24-30
AimThe purpose of this study was to investigate the prevalence of congenitally missing permanent teeth in Japanese children residing in south-west area of Kanto district in recent years.MethodsPanoramic radiographs taken for dental treatment between 1990 and 2007 were used to evaluate the congenitally missing permanent teeth excluding the third molar. The participants of this study consisted of 2,125 children aged between 7 and 20 years.ResultsThe congenitally missing teeth were observed in 251 participants (11.8%). The majority of the participants (114) presented with only one tooth missing, and there was a general tendency that the number of participants gradually decreased as the number of missing teeth increased. A total of 539 teeth were congenitally missing, and mandibular second premolar was the most frequently missing tooth (153 teeth), followed by mandibular lateral incisor (86 teeth), maxillary second premolar (71 teeth), maxillary lateral incisor (61 teeth). Only one missing tooth (114 participants) was found most frequently in mandibular lateral incisor (30 participants), followed by mandibular second premolar (28 participants). There was a tendency that congenitally missing teeth occurred symmetrically; especially most of the participants who had two missing teeth (80 in 88 participants) were symmetrically missing.ConclusionThe prevalence of congenitally missing permanent teeth in this study was 11.8% and it was comparable to those reported in previous studies of Japanese population evaluated using panoramic radiographs. 相似文献
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Dr. Dr. Thomas Michael Präger Christian Finke Rainer-Reginald Miethke 《Journal of orofacial orthopedics》2006,67(5):347-355
BACKGROUND: Ectodermal dysplasia is an inherited disease causing malformations of all tissues originating from the ectoderm. The significance of this disease lies in severe hypodontia, and an accompanying hypoplasia of the alveolar process. The clinical situation is aggravated by a significant xerostomia. It was the aim of this study to document the distribution of hypodontia and tooth malformation. Furthermore, we aimed to elucidate the clinical impact of these findings. PATIENTS AND METHODS: Records of 30 patients (19 males, 11 females) suffering from ectodermal dysplasia were included. Their age ranged between 7 and 23 years. All patients had been examined clinically and radiographically. In every patient, a record was made of which teeth were missing or malformed, and which deciduous teeth persisted. Additionally, the entire treatment procedure was assessed. RESULTS: The third molars were missing in all of the patients. The number of aplastic permanent teeth ranged from 2 to 26. The maxillary lateral incisors were most frequently absent, followed by the mandibular central incisors. The most stable teeth were the central incisors of the upper jaw, and the canines and first molars in both jaws. However, the maxillary central incisors and canines were the teeth most affected by malformation. Deciduous canines and second molars were the most often persisting teeth due to agenesis of the maxillary lateral permanent incisors and mandibular second premolars. In two-thirds of the patients, missing teeth were replaced by removable dentures. Half of the patients received orthodontic treatment. CONCLUSIONS: Hypodontia and malformation are almost regular dental characteristics in patients suffering from ectodermal dysplasia. The distribution of absent teeth deviates remarkably from the general population. Treatment requires an interdisciplinary approach including orthodontics, prosthodontics and oral surgery. 相似文献
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Sirpa Arte Minna Pöyhönen Emmi Myllymäki Elisa Ronkainen David P. Rice Pekka Nieminen 《Orthodontics & craniofacial research》2023,26(3):320-330
We aimed to characterize the genetic basis and craniofacial and dental features of Finnish patients with Axenfeld-Rieger syndrome (ARS). Mutational analyses of seven patients in five families were performed by sequencing or comparative genomic hybridization. Phenotypic analysis was based on both clinical and radiographic examinations, as well as on medical data. Lateral cephalometric radiographs of five patients were analysed using Viewbox 3.1-Cephalometric Software. The cephalometric values were compared to Finnish population-standard values of the same age and gender. Two frameshift mutations and three whole gene deletions were detected in five families. Class III skeletal relationship with retrognathic maxilla and mildly retrognathic mandible were detected in all five patients studied. Significant differences compared with the control values were in SNA (P = .0014), ANB (P = .0043) and SNB angles (P = .013). Five patients had anterior crossbite. Six patients showed tooth agenesis. The average number of missing teeth (third molars excluded) was 9 (range 0-15). The tooth agenesis rate was 52% in maxilla and 26% in mandible. Maxillary central and lateral permanent incisors were most often missing (rate 71% equally) while no one lacked canines or first molars in mandible. Two patients had a supernumerary mandibular permanent incisor. Six patients had either taurodontic and/or single-rooted molars. Our results suggest that class III skeletal relationship with maxillary and mandibular retrognathism, anterior crossbite, maxillary incisor agenesis and taurodontic, even pyramidal, roots are common determinants of ARS caused by PITX2 mutations. 相似文献
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STEEN RØLLING & SVEN POULSEN 《International journal of paediatric dentistry / the British Paedodontic Society [and] the International Association of Dentistry for Children》2009,19(3):172-175
Objective. The purpose of this study was to describe agenesis of permanent teeth in children with respect to prevalence and intra-oral distribution according to gender.
Methods and subjects. The study was population based and included all children in one district of the municipality of Aarhus, Denmark, in 1974–1979 (1657 girls and 1668 boys) and 1992–2002 (2409 girls and 2404 boys). The children underwent systematical clinical and radiographic examination.
Results. The period prevalence rates were almost identical for the two time periods (1972–1979: 7.8%; 1992–2002: 7.1%). Girls were affected more frequently than boys, and affected girls had more congenitally missing teeth than affected boys. Unilateral agenesis of the second premolars was more frequent than bilateral agenesis. In children with only one congenitally missing tooth, agenesis of the upper lateral incisors was asymmetrical in girls, but not in boys, whereas the opposite was true for the lower second premolars in boys.
Conclusion. The prevalence of agenesis of permanent teeth in Danish schoolchildren seems to be constant over time, and similar to that found in other large, population-based studies. Intra-oral distributions of congenitally missing teeth indicate gender-specific patterns. 相似文献
Methods and subjects. The study was population based and included all children in one district of the municipality of Aarhus, Denmark, in 1974–1979 (1657 girls and 1668 boys) and 1992–2002 (2409 girls and 2404 boys). The children underwent systematical clinical and radiographic examination.
Results. The period prevalence rates were almost identical for the two time periods (1972–1979: 7.8%; 1992–2002: 7.1%). Girls were affected more frequently than boys, and affected girls had more congenitally missing teeth than affected boys. Unilateral agenesis of the second premolars was more frequent than bilateral agenesis. In children with only one congenitally missing tooth, agenesis of the upper lateral incisors was asymmetrical in girls, but not in boys, whereas the opposite was true for the lower second premolars in boys.
Conclusion. The prevalence of agenesis of permanent teeth in Danish schoolchildren seems to be constant over time, and similar to that found in other large, population-based studies. Intra-oral distributions of congenitally missing teeth indicate gender-specific patterns. 相似文献
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OBJECTIVE: The purpose of this study was to assess the prevalence of dental caries, developmental defects of enamel, and related factors in children with clefts. DESIGN: This cross-sectional prevalence study used standard dental indices for assessment. SETTING: Children underwent a dental examination under standard conditions of seating and lighting in the outpatient department of a dental hospital as part of an ongoing audit to monitor clinical outcomes. PARTICIPANTS: Ninety-one children aged 4, 8, and 12 years were included in the study. OUTCOME MEASUREMENTS: Dental caries were assessed by use of the decayed, missing, and filled index for primary teeth (dmft); Decayed, Missing, and Filled index for permanent teeth (DMFT) according to the criteria as used in the national survey of children's dental health in the United Kingdom. Developmental defects were assessed using the modified Developmental Defects of Enamel Index (Clarkson and O'Mullane, 1989). Dental erosion was assessed using the criteria derived for the national survey of children's dental health. RESULTS: Caries prevalence increased with age; 63% of patients at 4 years and 34% at 12 years were caries free. The mean dmft for the 4-year-olds was 1.3 with a mean DMFT for the 12-year-olds of 1.8. All the 4-year-olds had evidence of erosion of enamel in the primary teeth (incisors and first molars) and 56% of the 12-year-olds had erosion of permanent teeth (incisors and first permanent molars). Developmental defects of enamel became more prevalent with age, with at least one opacity in 56% of 4-year-olds and 100% of 12-year-olds. Hypoplasia was not found in the primary dentition but affected permanent teeth in 38% of 8-year-olds and 23% of the 12-year-olds. CONCLUSION: This study has shown that dental disease is prevalent in these patients. These assessments not only provide a baseline on oral health parameters in young people with clefts but underline the need for a more aggressive approach to prevention of oral disease to optimize clinical outcome. 相似文献
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Seventy-three children with submucous cleft palate (38 girls and 35 boys), mean age 8.2 years (range 7.7-9.5), were studied retrospectively from orthopantomograms. Dental abnormalities in permanent dentition were found in 26 patients (36%). Missing teeth, mainly lower 2nd premolars, upper lateral incisors, and upper 2nd premolars, were found in 12 patients (16%). Most of the patients had 1 or 2 missing teeth, 2 had 3 missing teeth. In 5 patients hypodontia was associated with another dental abnormality. Other dental abnormalities included peg-shaped lateral incisors in 7 patients (10%), ectopic eruption of upper 1st molars in 6 patients (8%), transposition of upper canines and 1st premolars in 3 patients (4%), supernumerary teeth in 2 patients (3%), and palatally displaced upper canines in 1 patient (1%). As children with submucous cleft palate have a tendency towards increased frequency of missing teeth and other dental abnormalities, the need for thorough clinical and radiological dental examination is emphasized. 相似文献