急诊经皮冠状动脉介入治疗心肌梗死的疗效分析

目的探讨急诊经皮冠状动脉内支架置入治疗（PCI）急性心肌梗死（AMI）的临床疗效和安全性。方法回顾性分析本科收治的80例急诊经皮冠状动脉内支架置入治疗心肌梗死患者的临床资料,进行统计分析,总结经验。结果80例患者急诊PCI成功,术中支架置入成功率100％,平均住院12d,无严重并发症发生,术后3—12个月随访,无心绞痛及死亡病例,患者满意率高。结论对于胸痛〉12h而〈24h,有缺血症状和体征的患者,急诊PCI安全有效。     

经皮冠状动脉介入治疗急性心肌梗死86例临床研究

目的探讨经皮冠状动脉介入治疗急性心肌梗死的手术方法和临床疗效。方法对86例ST段抬高型急性心肌梗死患者发病12h内行急诊经皮冠脉介入（PCI）,梗死相关动脉置入支架。结果86例成功行PCI,置入支架90枚,无严重并发症。术后即刻TIMI血流3级者80例（93％）,2级者6例（6．9％）,术后随访1～16个月,无心脏事件发生,无死亡病例。结论急性心肌梗死行急诊PCI成功率高,效果好,并发症少。     

经桡动脉途径行急诊PCI治疗急性心肌梗死的临床体会

目的探讨经桡动脉途径行急诊冠状动脉介入治疗对急性心肌梗死患者的临床疗效及安全性。方法对48例急性心肌梗死在起病12h内进行急诊冠状动脉造影,对病变适合者行支架置入术,术后即刻行血管造影进行评价。结果 46例患者梗死相关动脉重建后血流为TIMI3级,基本无残余狭窄,1例因左主干完全闭塞未行支架置入术,1例三支病变均较重未行支架置入术。住院期间行支架置入术患者因心脏性死亡1例。其余45例患者随访6个月,无心血管事件发生。结论经桡动脉途径急诊冠状动脉介入治疗临床疗效可靠,而且穿刺部位并发症少,术后患者可在床上较自由地活动,较舒适。     

急性心肌梗死急诊介入性治疗的临床应用

目的　探讨急诊经皮冠状动脉腔内介入性治疗 (PCI)对急性心肌梗死 (AMI)的临床疗效。方法　分析我院近期急诊 PCI治疗 AMI患者 5 6例。结果　梗死相关动脉 (IRA)再通率为 98.2 % ,其中 5 1例患者植入冠状动脉内支架。随访 6～ 48个月 ,心绞痛症状复发 13例 ,其中 9例再次行 PCI术。结论　急性心肌梗死急诊PCI可即时开通 IRA ,大大降低了 AMI的住院死亡率 ,缩短了住院时间     

急性心肌梗死行经皮冠状动脉腔内血管成形术及支架置入的护理体会

目的探讨行急诊经皮冠状动脉腔内血管成形术及冠状动脉内支架置入术治疗急性心肌梗死的整体护理要点和注意事项。方法 2008年1月至2011年12月期间32例急性心梗患者行急诊经皮冠状动脉腔内血管成形术及冠状动脉内支架置入术,为减少手术并发症,降低病死率,采用术前加强心理护理及准备工作,术中医护密切的配合,术后严密观察病情,积极预防并发症的一套完整的护理程序。结果 32例患者中拔管时出现低血压4例,窦性心动过缓2例,发生皮下血肿3例,经过通过积极的治疗和精心的护理,患者术后均恢复良好,顺利出院。结论术前、术中、术后规范化护理作为该治疗的重要组成部分,对治疗的效果有重要的影响。     

经皮冠状动脉腔内成形术并冠脉内支架置入治疗急性心肌梗死

1999年4眉～2000年9月我院对28例急性心肌梗死(AMI)患者施行急诊经皮冠状动脉腔内成形术(PTCA)及支架置入术,现报告如下。     

PTCA及冠脉内支架术治疗急性心肌梗死

目的：评价经皮冠脉腔内成形术（PTCA）及冠脉内支架术治疗急性心肌梗死的临床疗效。方法：选择急性心肌梗死患17例，于发病1－2周内行冠脉造影术，同时对梗死相关血管行PTCA并直接置入冠脉内支架。术毕对靶血管造影评价支架置入后即刻疗效。长期随访观察心脏事件的发生率。结果：扩张包括梗死相关血管在内的21支病变血管共置入支架21次，手术成功率100％，即刻造影评价梗死相关血管达到TiMi3级血流，无并发症发生，平均随访2－14月，无心脏事件发生。结论：PTCA及冠脉内支架术治疗急性心肌梗死疗效确切，安全。     

冠状动脉内支架置入术对复杂性冠脉病变的治疗作用

探讨经皮冠状动脉腔内支架置入术治疗复杂性冠状动脉病变的疗效。对６１例６９支病变冠状动脉置入支架７２枚。置入前降支４５枚、回旋支５枚、右冠脉２２枚。结果：术后经冠脉造影证实疗效满意，支架置入的成功率为１００％，术后１例发生亚急性支架血栓形成，１例出现穿刺部位出血。结论：经皮冠状动脉内支架置入术治疗复杂性冠状动脉病变是一种安全有效的介入性治疗技术，其成功率高、并发症低     

冠状动脉支架术对老年冠心病患者28例治疗的临床分析

目的评价冠状动脉内支架置入术在老年冠心病患者治疗中的临床价值及安全性。方法将2004年l1月到2006年10月在我院接受冠状动脉支架术的患者分为老年组(>65岁)和对照组(<65岁),经股动脉或桡动脉入路进行经皮冠状动脉腔同支架置入术。结果老年组28例置入支架48枚,对照组30例共置入支架52枚。老年组和对照组冠状脉内支架置入手术成功率均为100%。老年组并发冠脉痉挛、冠脉夹层较对照组高,但无显著性差异(P>0.05)。结论冠状动脉内支架置入术是治疗老年冠心病患者的一种安全可靠、成功率高的介入治疗方法。     

介入与溶栓治疗急性心肌梗死的疗效研究

目的：对急性心肌梗死(AMI)行冠状动脉内成型加支架置入术的疗效与静脉内溶栓治疗进行对比评价。方法：对51例行急诊介入治疗的AMI患者，与同期146例行静脉内溶栓治疗的AMI患者进行对比研究。结果：急诊介入组梗死相关血管再通98.2％，其中TIMI--3级血流为96．5％。术中、术后无死亡病例。其中8例因3例支血管病变而行冠状动脉旁路移植术，术后随访3个月复发胸痛3例。静脉内溶栓组再通率67．1％，在院死亡13例。出院后随访3个月死亡5例，反复性胸痛及再梗死128例。结论：急诊介入是抢救心肌梗死，降低死亡率改善预后的最佳方法。     

Degraded and undegraded carrageenans and experimental gastric and duodenal ulceration

The prevention of histamine-induced gastric and duodenal ulceration in the guinea-pig has been examined using a series of undegraded and degraded carrageenans. Undegraded carrageenans were active at lower doses than degraded carrageenans. The high viscosity of the undegraded carrageenans in solution prevented their use in larger doses. Degradation of carrageenan without serious loss of sulphate, gives a product which allows the dose to be increased to an extent that its effect more than offsets the slight loss in activity caused by the degradation. No single feature of carrageenan structure can be related to anti-ulcer activity although degradation, and hence reduction of molecular size, generally reduces activity. Sulphate contents over 30% have little apparent effect on activity; κ-carrageenans were not consistently different in anti-ulcer activity from Λ-carrageenans. This contrasts with the antipeptic activity of carrageenans where κ-carrageenans are less active than their Λ-counter-parts. As with antipeptic activity, the degree of anti-ulcer activity is probably determined by a combination of structural features which includes molecular size and polyanionic properties.     

Affective and Anxiety Disorders and Alcohol and Drug Dependence:

Depression and anxiety frequently coexist in patients with substance use disorders. This clinically-oriented article examiens the relationship between these conditions and emphasizes data showing that substances of abuse can cause signs and symptoms of both depression and anxiety. These substance-related syndromes appear to have a different course and prognosis than uncomplicated, independent anxiety and major depressive disorders, and clinicians should consider the role of alcohol and other drugs in all patients presenting with these complaints. The authors will also outline an approach for diagnosing and managing patients with the combination of a substance use and depressive or anxiety disorder.     

Alcohol and Substance Use and Abuse in Women and Children

No abstract available for this article.     

Glucosidase and fucosidase inhibitors and Advances in nucleosides and nucleotides.

The American Chemical Society Symposium "Glucosidase and fucosidase inhibitors" took place on 1 April 1998 and was organized by Professors Zbigniew J Witczak (UConn, School of Pharmacy, CT, USA), Kuniaki Tatsuta (Waseda University, Tokyo, Japan) and Waldemar Priebe, MD (Anderson Cancer Center, University of Texas, USA). Professor Witczak provided introductory remarks including the status of existing glucosidase inhibitors, and chaired the morning session, which consisted of six lectures. The symposium was well received, and was particularly attractive for those interested in networking, as attendance was about sixty. In addition, some participants and attendees presented posters on the subject during the regular poster session organized by the Division of Carbohydrate Chemistry.