首页 | 本学科首页   官方微博 | 高级检索  
相似文献
 共查询到20条相似文献,搜索用时 78 毫秒
1.
海水浸泡对烧冲复合伤犬血流动力学的影响   总被引:1,自引:0,他引:1  
目的:建立犬烧冲复合伤后海水浸泡的实验模型,探讨海水浸泡对烧冲复合伤犬血流动力学的影响。方法:17只健康成年杂交犬随机分为两组,对照组:致烧冲复合伤后直接观察(n=7);浸泡组:致伤后置入21℃海水中浸泡4h(n=10),于致伤前及伤后4h、7h、10h、20h、28h测定血流动力学指标。结果:浸泡组出水后犬血流动力学各指标显著恶化,外周平均动脉压(MAP)、心脏指数(CI)、左室每搏功指数(LVSWI)等持续下降;而全身血管阻力指数(SVRJ)随时间延长呈恢复趋势。对照组致伤前后多数血流动力学指标无显著变化。结论:海水浸泡可导致实验犬血流动力学状况明显恶化。  相似文献   

2.
海水浸泡对犬弹烧复合伤伤情特点的影响   总被引:3,自引:0,他引:3  
目的研究海水浸泡对弹烧复合伤动物的致伤特点,方法成功建立海水浸泡弹烧复合伤模型后,依模型将15只成年杂种犬随机分为单纯弹烧复合伤组(简称非浸泡组)7只和海水浸泡弹烧复合伤组(简称浸泡组)8只.动态监测伤前、伤后4.7.10,20,28h共6个时相点体温(T)、心率(HR)、平均动脉压(MAP)、平均肺动脉压(MPAP)、中心静脉压(CVP)、肺毛细血管楔压(PCWP)、心脏指数(CI).计算每搏输出指数(SVI)、外周循环阻力指数(SVRI)、肺循环阻力指数(PVRI)、左室每搏功输出指数(LVSWI)、右室每搏功输出指数(RVSWI)。结果动物海水浸泡后,体温明显降低;心率、平均动脉压、中心静脉压、肺毛细血管楔压、心脏指数、每搏输出指数明显下降;外周循环阻力指数、肺循环阻力指数明显增高;左室每搏功输出指数、右室每搏功输出指数明显下降。结论海水浸泡明显加重动物伤情。实验动物中心体温明显下降;血流动力学紊乱明显加重,休克出现早.致动物死亡时间提前.死亡率增高。  相似文献   

3.
目的 比较两种复合战伤 (烧冲复合伤和弹烧复合伤 )合并海水浸泡对血管内皮细胞影响的特点和机制。方法 建立烧冲、弹烧复合伤的犬实验模型 ,将实验犬按致伤类型随机分为两组 ,即烧冲复合伤组和弹烧复合伤组 ,各 2 0只。致伤后置入海水中浸泡 ,4 h后捞出 ,于伤前、伤后 4 ,7,10 ,2 0和 2 8h分别取血检测循环内皮细胞 (CEC)和血管性假血友病因子 (v WF)。结果  (1) CEC计数 :烧冲伤合并海水浸泡在伤后 4 h明显增加 ,伤后 7h为 6个时相点的最高值 ,之后呈缓慢下降趋势 ;而弹烧伤合并海水浸泡在伤后 4 h明显增加 ,之后随时间延长呈加重趋势 ,在伤后 2 8h达最高峰值。伤后 4 ,7,2 0和 2 8h烧冲伤与弹烧伤的 CEC变化相比差异有非常显著性 (P<0 .0 1)。 (2 ) v WF:烧冲伤合并海水浸泡在伤后 4 h为 6个时相点的最高值 ,而弹烧伤合并海水浸泡在伤后 2 8h才达到峰值。伤后 4 ,2 0和 2 8h烧冲伤与弹烧伤的v WF变化差异有显著性 (P<0 .0 5或 0 .0 1)。结论 烧冲复合伤合并海水浸泡对 CEC损伤的峰值一般在伤后 4 h或 7h;弹烧复合伤合并海水浸泡对 CEC损伤的峰值延后 ,一般在伤后 2 0 h或 2 8h。  相似文献   

4.
目的 分析犬多部位伤海水浸泡后血流动力学特点,为海水浸泡多部位伤的早期救治提供理论依据。方法 成年杂种犬30只,制作多部位伤动物模型,随机分为致伤浸泡组(n=10)、致伤非浸泡组(n=10)和非致伤浸泡组(n=10)。观察犬多部位伤后在血流动力学变化规律。结果 犬多部位伤海水浸泡后,平均动脉压(MAP)、中心静脉压(CVP)和心输出量(CO)下降等血流动力学明显紊乱。致伤非浸泡组犬MAP和CO早期一过性升高,随后缓慢下降;浸泡非致伤组血流动力学在浸泡早期无明显变化,浸泡后1.5~2小时MAP、CVP和CO等指标出现轻度下降。结论 海水浸泡导致的高渗性脱水、体温过低等病理生理学改变是引起犬多部位伤后血流动力学紊乱,引起犬早期死亡率的主要因素。  相似文献   

5.
犬肠管破裂伤合并海水浸泡后血流动力学及病理学变化   总被引:4,自引:3,他引:1  
目的 分析犬肠管破裂伤合并海水浸泡后血流动力学及病理学变化的特点,为海战肠管破裂伤的早期救治提供理论依据。方法 成年杂种犬30只,制作肠管破裂伤动物模型,随机分为海水浸泡组(n=10)、生理盐水浸泡组(n=10)和对照组(n=10)。前两组伤后分别浸泡于人工海水和生理盐水中,对照组单纯致伤不浸泡。观察犬肠管破裂伤后在血流动力学及病理学的变化规律。结果 肠管破裂伤合并海水浸泡后出现明显的平均动脉压(MAP)、肺动脉嵌压(PAWP)、中心静脉压(CVP)和心排出量(CO)下降等血流动力学紊乱及重要器官损伤的病理学改变。生理盐水浸泡组和对照组在致伤前后无明显血流动力学及病理学变化。结论 海水浸泡是导致犬肠管破裂伤合并海水浸泡后血流动力学紊乱的主要因素。  相似文献   

6.
目的 观察高压氧对犬严重肺冲击伤的治疗效果。方法 将 18条成年犬随机分为对照组与高压氧治疗组。用BST 1生物激波管造成犬严重肺冲击伤 ,对照组伤后立即给予吸氧、补液、抗感染等处理 ;高压氧治疗组在以上处理基础上于伤后 5小时给予高压氧治疗。两组均于伤前及伤后 0 .5、4、8、12小时等时相点检测血气与血流动力学指标 ,观察伤后 2 4小时内肺体指数及死亡率。结果 两组动物伤后血气及血流动力学指标均发生严重紊乱 ,HR、sBP、PO2 、SO2 、CI、CO及LCW等指标明显下降 ,而SVR、SVRI显著增高 ,但治疗后高压氧治疗组PO2 略高于对照组 ,而SVR、SVRI略低于对照组。对照组伤后 2 4小时肺体指数为 (1.83± 0 .38) % ,死亡率为 4 0 % ;高压氧治疗组伤后 2 4小时肺体指数为 (1.35± 0 .19) % ,明显低于对照组 (P <0 .0 5 ) ,死亡率仅为 12 .5 %。结论 高压氧对犬严重肺冲击伤具有一定治疗作用  相似文献   

7.
犬弹片伤复合烧伤海水浸泡后血液流变学的影响   总被引:3,自引:0,他引:3  
目的 研究犬弹片伤复合烧伤海水浸泡后血液流变学的影响。方法 成功建立海水浸泡弹片伤复合烧伤(简称弹烧复合伤)模型后,依模型将15只成年杂种犬随机分为单纯弹烧复合伤组(简称非浸泡组7只)和海水浸泡弹烧复合伤组(简称浸泡组8只),动态监测伤前、伤后4、7、10、20、28小时共6个时相点血液流变学变化。结果 (1)两组动物血浆粘度与伤前比较变化均不明显;全血粘度浸泡组伤后较非浸泡组增高明显;(2)两组伤后血球压积均较伤前增高,在早期两组间相差不明显,但在致伤20小时后浸泡组明显高于非浸泡组;(3)红细胞聚集性浸泡组伤后增高更明显,而红细胞变形性下降更显著。结论 海水浸泡明显加重血液流变学紊乱,由此进一步加重微循环障碍,从而进一步加重海水浸泡弹烧复合伤动物伤情,致死亡时间提前,死亡率增高。  相似文献   

8.
烧冲复合伤合并海水浸泡对犬血管内皮细胞的影响   总被引:1,自引:0,他引:1  
目的 探讨烧冲复合伤合并海水浸泡对血管内皮细胞影响的原因和机制 ,为海水浸泡伤早期救治提供一定的理论依据。方法 建立烧冲复合伤的犬实验模型 ,致伤后将犬随机分为非浸泡组和浸泡组 ,将浸泡组犬在海水中浸泡 4小时后捞出 ,然后于伤后 4、7、10、2 0小时和 2 8小时分别取血检测循环内皮细胞 (CEC)以及血管性假血友病因子 (vWF)的变化。非浸泡组除不浸泡海水外 ,余检测时相及指标同浸泡组。结果 非浸泡组在致伤后 4小时CEC和vWF明显增高 (P <0 .0 5 ) ,而浸泡组于伤后 4、7、10、2 0小时和2 8小时的CEC和vWF均明显增高 (P <0 .0 5或P <0 .0 1) ;组间比较发现浸泡组从伤后 4小时至 2 8小时各指标均与非浸泡组有显著差异 (P <0 .0 5或P <0 .0 1)。结论 烧冲复合伤合并海水浸泡伤后可引起全身EC急性损伤 ,并且这种损伤比单纯烧冲复合伤 (不浸泡 )更严重 ,更持久。  相似文献   

9.
目的 探讨Parkland公式复苏对犬弹烧复合伤并海水浸泡后血气及酸碱水平的影响。方法 建立海水浸泡弹烧复合伤动物模型后,将14只成年杂种犬随机分为海水浸泡弹烧复合伤组(简称浸泡组,n=8)和Parkland公式复苏组(简称复苏组,n=6),动态监测伤前及伤后4,7,10,20,28h(共6个时相点)血气及酸碱水平的变化。结果 (1)浸泡组动物在浸泡后出现进行性加重的、严重的代谢性酸中毒;Parkland公式复苏后,在实验早期改善了代谢性酸中毒,但在实验后期(伤后28h)代谢性酸中毒状况与浸泡组相同。(2)浸泡组动物在浸泡后动脉血氧分压明显下降,出水后略有回升,但仍明显低于伤前水平,复苏组与浸泡组动脉血氧分压在各时相点相差不显著。伤后4h测量点(浸泡后即刻)二氧化碳分压与伤前比较无明显差异。在伤后10h内,二氧化碳分压复苏组与浸泡组变化接近;但从伤后20h开始,则明显低于浸泡组。结论 以Parkland公式为参照进行常规复苏时,在一定程度上可以纠正海水浸泡后进行性加重的、严重的代谢性酸中毒(伤后20h内),但这种改善作用不稳定,表现为代谢性酸中毒在伤后28h时进一步恶化,因此,复苏措施需要进一步改进。  相似文献   

10.
犬胸部开放伤后海水浸泡血流动力学变化   总被引:9,自引:4,他引:5  
目的 建立犬开放性气胸海水浸泡的实验模型,观察实验动物血流动力变化。方法 实验动物致伤后随机分为对照组(n=10)和海水浸泡组(n=10)。海水浸泡组动物于伤后置入人工配制的海水中,于伤前及入水后0.5小时、1小时、2小时、3小时和4小时监测血流动力学变化。结果 海水浸泡组的血流动力学紊乱明显重于对照组,死亡率明显高于对照组,平均生存时间为45分钟。结论 胸部开放伤后海水浸泡可引起一系列严重的病理生理变化,其血流动力学变化与单纯胸外伤明显不同,提示海水浸泡对机体的损伤程度更为严重,结果导致实验动物早期高死亡率。  相似文献   

11.
12.
成批煤气爆燃烧伤的救治体会   总被引:1,自引:0,他引:1  
报道治疗因煤气泄漏爆炸烧伤病员7例,经应用MEBT技术积极救治,其中6例于伤后17天痊愈出院,另一例特重伤员也于伤后30天康复出院。作者认为:应严格按照MEBT/MEBO要求进行规范治疗,正确处理生命体征、休克、感染、脏器功能和创面的辨证关系。同时,不能忽视外科营养在过程中的重要作用,它是创面修复的物质保证。  相似文献   

13.
In situations of stress, such as clinical trauma, starvation or prolonged, strenuous exercise, the concentration of glutamine in the blood is decreased, often substantially. In endurance athletes this decrease occurs concomitantly with relatively transient immunodepression. Glutamine is used as a fuel by some cells of the immune system. Provision of glutamine or a glutamine precursor, such as branched chain amino acids, has been seen to have a beneficial effect on gut function, on morbidity and mortality, and on some aspects of immune cell function in clinical studies. It has also been seen to decrease the self-reported incidence of illness in endurance athletes. So far, there is no firm evidence as to precisely which aspect of the immune system is affected by glutamine feeding during the transient immunodepression that occurs after prolonged, strenuous exercise. However, there is increasing evidence that neutrophils may be implicated. Other aspects of glutamine and glutamine supplementation are also addressed.  相似文献   

14.
新疆石河子地区奶牛隐性乳房炎的调查与分析   总被引:1,自引:0,他引:1  
采用LMT法对新疆石河子地区三个规模化奶牛场泌乳牛群进行了隐性乳房炎检测,共检测994头泌乳牛3976个乳区.结果表明:奶牛隐性乳房炎阳性率为81.9%,乳区阳性率为49.1%.数据分析表明,不同年龄、胎次以及有无卧床奶牛的隐性乳房炎阳性率差异显著(P<0.05),后乳区的隐性乳房炎感染率显著高于前乳区感染率(P<0.05),隐性乳房炎乳区发生数也明显影响当日产奶量(P<0.05).  相似文献   

15.

Objectives

Women are resistant to neuromuscular fatigue compared to men in response to a range of exercise tasks. The sex differences in the neuromuscular responses to load carriage have yet to be investigated.

Design

Prospective cohort study.

Methods

Twenty-three male and 19 female British Army recruits completed a 9.7 km loaded march within 90 min, with the weight carried dependent on military trade (16 ± 2 kg for men and 15 ± 1 kg for women). Isometric maximal voluntary contraction (MVC) force of the knee extensors and vertical jump (VJ) height were examined pre- and post-loaded march to examine neuromuscular fatigue. Heart rate (HR) was recorded throughout and ratings of perceived exertion (RPE) was recorded following the march.

Results

HR was higher for women (173 ± 9 b min?1, 83 ± 6% heart rate reserve) than men (158 ± 8 b min?1, 72 ± 6% heart rate reserve) (p  0.001). RPE following the march was also higher for women than men (6 ± 2 vs 4 ± 2, respectively, p < 0.001). The loss in MVC force was greater for men than women (?12 ± 9% vs ?9 ± 13%, respectively, p = 0.031), however VJ height was impaired to a similar extent (?5 ± 11% vs ?5 ± 6%, respectively, p = 0.582).

Conclusions

The greater physiological stress during load carriage for women compared to men did not translate to a greater severity of knee extensor muscle fatigue, with women demonstrating fatigue resistance.  相似文献   

16.

Background

The local muscular endurance of knee flexors, during eccentric work in particular, is important in preventing or delaying kinematic changes associated with fatigue during treadmill running. This result, however, may not be transferable to overground running.

Objective

To test the hypothesis that overground running is associated with eccentric hamstring fatigue.

Methods

Thirteen runners (12 male and one female) performed an isokinetic muscle test three to four days before and 18 hours after a marathon. Both legs were tested. The testing protocol consisted of concentric and eccentric quadriceps and hamstring contractions.

Results

There were no significant differences between peak torque before and after the race, except that eccentric peak hamstring torque (both thighs) was reduced.

Conclusion

Overground running (running a marathon) is associated with eccentric hamstring fatigue. Eccentric hamstring fatigue may be a potential risk factor for knee and soft tissue injuries during running. Eccentric hamstring training should therefore be introduced as an integral part of the training programme of runners.  相似文献   

17.
目的:对42例肺心病慢性呼吸性酸中毒患者的80例次血气测定结果。方法:用不同的酸碱图(卡)及代偿公式进行酸碱类型的初步差别分析。结果:结合临床表现、各种影响因素与治疗反应等作出综合判定。结论:比较二种判定的差异,并提出较为实用、可靠的判断建议,以助于复合型呼吸性酸碱失衡的临床诊断与处理。  相似文献   

18.
Primary hyperoxaluria (PH1) is a rare inborn autosomal recessive metabolic disorder due to the deficiency of hepatic alanine-glyoxylate-aminotransferase. This deficiency results in excessive synthesis and urinary excretion of oxalate, inducing renal stone formation and deposition of calcium oxalate in the kidney, bone, myocardium, and vessels (systemic oxalosis, SO) in the most severely affected individuals. We report renal and skeletal changes in a 3-month-old girl with PH1 and SO. Intense cortico-medullary hyperechogenicity and increased homogeneous radiopacity of normal-sized kidneys suggested the diagnosis of SO. Skeletal survey showed osteopenia and characteristic symmetrical metaphyseal transverse bands in long bones, progressively becoming more dense and migrating towards the diaphysis. Multiple pathological and slowly healing fractures of the limbs occurred at the dense band level. A radiopaque rim was then observed in flat bones, epiphyseal nuclei, and vertebral bodies. Inflammatory granulomatous reaction, induced by the presence of oxalate crystals in the marrow spaces, coexisted with progressively evident radiological signs of secondary hyperparathyroidism, with partially overlapping features. The patient was treated by peritoneal dialysis and hemodialysis until combined liver–kidney transplantation. There are no previous reports of infants treated with hemodialysis for more than 2 years.  相似文献   

19.
Interventional oncology in private practice requires expert training and can be performed in a stand-alone facility for type 1 procedures in a hospital setting for type 2 and 3 procedures where subspecialized radiologists, state-of-the-art equipment, and postprocedure hospital monitoring are available. A multidisciplinary effort with oncologists, internal medicine physicians and anesthesiologists is necessary. The practice of interventional oncology requires around the clock availability, meticulous and established protocols and procedures and a financial investment. On the other hand, it is professionally gratifying because of constant technical advances and the impact on patients.  相似文献   

20.
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号