共查询到20条相似文献,搜索用时 15 毫秒
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Basaloidsquamouscarcinomaoftheesophagus:clinicopathological,immunohistochemicalandelectronmicroscopicstudiesof16casesZhangXin... 相似文献
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李光容 《华西医科大学学报》1989,20(3):295-298
The light and electron microscopic observations were carried out in 50 cases of colon specimens. No remarkable morphologic differences were found between the epithelial cells of the mucosa with schistosomiasis, colitis and the normal specimens. Cells of the colon carcinoma also showed no significant difference from those of the colon carcinoma associated with schistosomiasis. Atypical changes in the epithelial cells were not seen in the areas both adjacent to and remote from the carcinoma and in the egg deposit areas. Under LM, changes were manifested in various degrees in degeneration and disassociation of mucosal cells in colitis (1), schistosomiasis (1) and carcinoma associated with schistosomiasis (8). Under EM, changes in mucosal muscle cells were seen in colon carcinoma (2) and carcinoma associated with schistosomiasis (5). Proliferation of fibroblasts and hyperchromasia of the nuclei were noted in 3 cases of carcinoma associated with schistosomiasis. The pathological changes mentioned above were more prominent in cases of carcinoma associated with schistosomiasis than in those of colon carcinoma alone. The authors believed that the cause was non-specific changes induced by the toxin of the egg mechanical effects rather than a direct carcinogenic action of the eggs, and that the non-specific changes implied no direct relationship between the development of colon carcinoma and schistosomiasis. 相似文献
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An immunohistochemical analysis using a series of mono- and polyclonal antibodies against myoglobin, desmin, vimentin, actin, NSE, S-100 protein and keratin was done on alveolar rhabdomyosarcoma (3 cases), embryonal (3) and pleomorphic rhabdomyosarcoma of the orbit (1). All tumors were stained by monoclonal antibodies to desmin and vimentin, whereas 6 of the 7 cases were stained by myoglobin. The results indicate that desmin and vimentin are highly sensitive immunohistochemical markers for the diagnosis of rhabdomyosarcoma, especially in poorly differentiated ones.
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用透射电镜观察了45例原发性肺癌超微结构。结果表明:经光镜诊断的各型肺癌在电镜下可以表现为不同的其他类型:大细胞癌可表现为腺癌、鳞癌、腺鳞癌和未分化癌的超微结构特征。各型肺癌细胞浆内均可见板层小体。细胞内微腔由细胞膜反折形成。腺鳞癌在电镜下比例升高,可能与绝大多数肺癌起自呼吸道上皮的基底细胞及粘液细胞有关。 相似文献
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T Okina K Esaki A Nagata J Kusukawa C Koga Y Nagao M Uchiyama M Ohgusu T Kameyama H Wakae 《The Kurume medical journal》1990,37(4):293-299
Two cases of congenital epulis occurring in the gingiva at the site where the lower deciduous incisors were to erupt are described. The first patient was a 7 day-old female infant. Her epulis was diagnosed, histopathologically, as a granular cell tumor. Electron microscopy revealed that the tumor cells were large with small eccentric nuclei. The cells were filled with granular structures. These granular substances varied in size and electron density. Case 2 involved a 37 day-old male infant. A histopathological diagnosis of fibromatosis was made. Electron micrographs showed a proliferation of cells which resembled fibroblasts. These cells varied in shape, including some with thin, long processes. Abundant reticular and collagen fibers were present in the stroma. In both cases, the postoperative course was uneventful without recurrence. 相似文献
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目的:探讨丙型肝炎患者外周血单个核细胞(PBMCs)内丙型肝炎病毒抗原(HCVAg)表达和HCV颗粒感染状况及意义。方法:采用抗HCV核心区及NS3区单克隆抗体,对35例慢性丙肝患者PBMCs进行免疫组化检测和电镜观察。结果:慢性丙肝患者PBMCs的HCVAg阳性率为82.9%(29/35),其中82.8%(24/29)的病例电镜下发现了病毒颗粒,占全组病例的68.6%(24/35)。同时发现部分细胞超微结构呈现一系列凋亡性改变。结论:HCV可感染PBMCs并在其中复制,这可能是导致患者HCV持续感染的原因之一。 相似文献
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目的:探讨胃癌的临床特点以及内镜、CT对胃癌的术前诊断价值。方法:对60例手术切除,且具备内镜、CT检查资料的进展期胃癌病例进行回顾性分析。结果:胃癌的临床表现缺乏特异性;内镜是直接、准确的检查方法,对肿瘤腔内的诊断准确率达95.0%;CT能估计肿瘤的腔外扩展情况。结论:重视非特异性临床表现,综合内镜、CT检查能提高对胃癌的术前诊断水平,从而使胃癌得到及早诊断和合理治疗。 相似文献
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Subtypes of intestinal metaplasia and gastric carcinoma. A clinicoendoscopic follow-up of 112 cases. 总被引:2,自引:0,他引:2
Nine tumor-associated antigens (MG7-, MGdl-, MC3-corresponding antigens, CEA, P21ras, Sialoglycoprotein, CA 19-9-like, Sialo-Tn and Le8-like antigens) were investigated on biopsy specimens of different types of intestinal metaplasia (types I, II and III) taken from 112 patients with benign gastric conditions. The incidence of positive staining for 9 antigens except for P21ras in type III intestinal metaplasia was significantly higher than that in types I and II (P less than 0.05-0.01). These 112 patients were clinicoendoscopically followed up for 15-70 months. Five of them were found to develop gastric carcinomas within 25-60 months, giving a cancer detection rate of 4.5%. They were detected from type III (16.1%) patients, but none was found in patients of types I and II, and the differences were significant (P less than 0.05-0.01). Our results indicate that type III intestinal metaplasia has a higher potentiality in developing malignancy and that MG7, MGd1, MC3, CEA, CA19-9-like and Sialo-Tn antigens are valuable tumor markers in defining the high-risk group of gastric carcinoma.
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