Long-term follow-up of polytetrafluoroethylene-covered stents implanted during percutaneous coronary intervention for management of acute coronary perforation

Objective : To determine the long‐term outcomes for patients receiving polytetrafluoroethylene (PTFE)‐covered stents as definitive therapy, in our institution, for the management of acute coronary perforation. Background : Coronary perforation as a complication of percutaneous coronary intervention (PCI) is associated with high morbidity and mortality. Management options included observation only or a combination of several or all of these approaches: reversal of anticoagulation, prolonged balloon inflation, deployment of a standard stent, emergent cardiac surgery, or insertion of a PTFE‐covered stent. Methods : With our IRB approval, records of 12,093 consecutive patients who received PCI during a 5‐year period from January 2002 to December 2006 were reviewed and 50 patients who had coronary perforation as a complication of PCI were identified. Results : Of the 21 patients who received a PTFE‐covered stent to manage coronary perforation, one died secondary to acute thrombosis within the PTFE‐covered stent in the first 24 hrs and one required emergent cardiac surgery due to continued contrast extravasation despite PTFE‐covered stent deployment. The other 19 patients were followed long term (mean 55 months) and only one survivor had a potentially life‐threatening outcome (subacute stent thrombosis) over that time period. Conclusion : Utilization of a PTFE‐covered stent may be a reasonable short‐ and long‐term option to manage acute coronary perforation that occurs during PCI. On the basis of this limited experience, successful PTFE‐covered stent deployment as the conclusive treatment for coronary perforation is associated with a favorable long‐term event‐free survival rate. © 2011 Wiley Periodicals, Inc.     

Challenges associated with treatment of left internal mammary artery graft thrombosis

Acute occlusion of the left internal mammary artery (LIMA) graft late after coronary artery bypass grafting surgery is a rare and potentially life‐threatening complication. We describe a case of acute myocardial infarction 19 years after coronary artery bypass graft surgery due to acute occlusion of the distal anastomosis of a LIMA graft to the left anterior descending artery. Aspiration thrombectomy failed to remove the thrombus. Laser thrombectomy caused perforation. After drug‐eluting and covered stent implantation, antegrade TIMI 3 flow was restored with an uneventful postprocedural course.     

Guideliner microcatheter to improve back-up support during a complex coronary stenting procedure through a tortuous left internal mammary graft

Back-up support during percutaneous coronary interventions (PCI) is one of the keys for successful intervention. Extra back-up support guiding catheters, deep intubation, buddy wires, and other more complex techniques are usually used to improve this support. Left anterior descending (LAD) artery PCI through the left internal mammary artery (LIMA) are rarely performed because many operators feel reluctant to instrument a disease-free LIMA graft risking iatrogenic complications by passing wire, balloons, and stents to the diseased distal LAD. Improving back-up support during LIMA-LAD PCIs is often challenging because in this particular setting the distance between the LAD lesion and the guiding catheter is exceedingly long. We report a case of a challenging PCI of the LAD through a patent and disease-free LIMA graft. After multiple failed attempts to cross the LAD lesion with conventional stent deployment techniques, we successfully finished the stenting procedure using the Guideliner microcatheter (Vascular Solutions) as a guiding extension through the LIMA graft. With this case, we illustrate that this microcatheter dramatically improves the back-up support, allowing stent deployment also in very difficult settings as in tortuous LIMA grafts.     

Coronary artery perforation in patients undergoing percutaneous coronary intervention: a single-centre report

The present study reports the incidence, management and clinical outcome of coronary perforations in 5 of 2991 patients (0.1%) undergoing percutaneous coronary intervention, with non-debulking (percutaneous transluminal coronary angioplasty and stent) techniques. There was 1 type I, 1 type II and 3 type III perforations. One perforation was guidewire related, 2 perforations occurred after stent deployment and two occurred during stent-post dilatation with balloons. Restoration was obtained by prolong balloon inflation in three cases. Subsequent cardiac tamponade occurred in 2 patients, requiring pericardiocentesis. One patient died in the cath lab. due to electromechanical dissociation. At follow-up, 3 out of 4 patients were asymptomatic and one had bypass surgery for restenosis. Treatment of coronary perforation requires rapid detection, angiographic classification, and immediate occlusion of perforation site, pericardiocentesis, haemodynamic support and reversal of heparin anticoagulation.     

Fatal stent thrombosis following successful treatment of coronary artery rupture in an octogenarian

Primary intracoronary stenting of a calcified left anterior descending coronary artery stenosis was complicated by within-stent coronary artery rupture and subsequent cardiac tamponade. Despite pericardiocentesis and sealing of the perforation by additional stent placement, subsequent stent thrombosis resulted in anterior myocardial infarction and fatal cardiogenic shock. Cathet. Cardiovasc. Diagn. 42:434–436, 1997. © 1997 Wiley-Liss, Inc.     

Dual-catheter covered stenting: a novel approach to the treatment of large coronary artery perforations

Coronary perforation is an infrequent but potentially devastating complication of coronary intervention. Treatment of a broad-based perforation usually requires emergent pericardiocentesis and thoracotomy. We present a novel approach to closure of > or = 1 mm diameter perforations using a dual-catheter covered stent technique.     

Aortic valve perforation during aortic valvuloplasty

Balloon aortic valvuloplasty has seen a revival in interest because of its role in predilation and preparation of the annulus before trans catheter aortic valve implantation. Aortic valve cusp perforation is a serious complication that needs early recognition and prompt corrective measures to prevent a poor procedural outcome or conversion to emergent surgery. A number of useful angiographic and technical findings can alert the operator about the possibility of this complication. Failure to recognize cusp perforation can lead to serious procedural complications like severe aortic regurgitation, suboptimal prosthesis deployment, and function that can necessitate emergent open cardiac surgery © 2011 Wiley‐Liss, Inc.     

Cardiac tamponade following stent implantation with adjuvant platelet IIb/IIIa receptor inhibitor administration

This case report describes a previously unreported complication of stent implantation in association with the use of adjuvant platelet IIb/IIIa receptor inhibitor administration. Following stent implantation, the patient developed cardiac tamponade, treated successfully with percutaneous pericardiocentesis and autologous platelet administration. Cathet. Cardiovasc. Diagn. 40:380–382, 1997. © 1997 Wiley-Liss, Inc.     

Modified dual guide catheter (“ping‐pong”) technique to treat left internal mammary artery graft perforation

Perforation of a left internal mammary artery (LIMA) graft during percutaneous coronary intervention is a rare event. We report a case of mid‐LIMA perforation treated by a polytetrafluoroethylene‐covered stent using a modification of the dual catheter (“ping pong”) technique. We propose that use of this modification when possible will further improve safety of treating a perforation. © 2014 Wiley Periodicals, Inc.     

Dissecting Sub-epicardial Hematoma Due to Coronary Perforation and Non-developing Stent

We report a 65-year-old man who presented with anastomotic perforation of the distal right coronary artery due to stent deployment, complicated by a small and stable dissecting sub-epicardial hematoma, and non-developing stent. The cause was unknown.     

Percutaneous transluminal laser guide wire recanalization of chronic subclavian artery occlusion in symptomatic coronary-subclavian steal syndrome.

Treatment of subclavian artery stenosis by percutaneous balloon angioplasty and adjunctive stent placement was shown to be safe and efficacious, but it may be limited in tight stenoses and long occlusions. We describe the case of a patient who experienced progressive angina pectoris associated with signs of cerebrovertebral insufficiency 9 yr after bypass surgery, including left internal mammary artery (LIMA) grafting to the left anterior descending coronary artery. Angiography showed reversed flow through the LIMA graft into the subclavian artery and a 4-cm occlusion beginning at the origin of the left subclavian artery, representing a rare coronary-subclavian steal syndrome. After a conventional approach failed, recanalization was performed successfully using laser guide wire angioplasty with adjunctive stent placement in a combined radial and femoral approach.     

Delayed Ischemic Cecal Perforation Despite Optimal Decompression After Placement of a Self-Expanding Metal Stent: Report of a Case

Endoscopic deployment of self-expanding metal stents offers an alternative to surgical intervention in rectocolonic obstructions. Reported clinical failures in the literature are all related to the site of stent placement. We report a case of serious intra-abdominal disease after technically and clinically successful stent deployment: a potentially dangerous situation of which the surgeon should be aware. A previously healthy 72-year-old female was referred to our department with symptoms of an obstructing colorectal tumor. Successful stent placement resulted in resolution of the obstructive condition. Three days after stent deployment, x-ray examinations revealed a small-bowel obstruction and emergency surgery was performed. Intraoperative findings demonstrated a segment of ileum fixated to the tumor in the small pelvis, resulting in the obstructive condition. Furthermore, a cecal perforation, probably caused by ischemic conditions developed before stent-decompression of the colon was revealed during the operation. The patient died in the postoperative course. We discuss the observation of patients treated with self-expanding metal stents based on the selection-strategy used to allocate patients to this specific treatment. We conclude that although a patient is eligible for treatment with self-expanding metal stents, large-bowel obstruction can be too old for stent-decompression, causing ischemic perforation of the colon. Furthermore, we underline the need to focus on the possibility of obstructions other than those being treated.     

Use of stents to treat kinks causing obstruction in a left internal mammary artery graft

Left internal mammary arteries (LIMA) are used routinely as grafts to the left anterior descending coronary artery (LAD) in selected patients undergoing coronary artery bypass graft (CABG) surgery because of better long-term patency rates. Pathology other than fibrointimal hyperplasia, accelerated atherosclerosis, or thrombus can sometimes cause obstructive lesions in such grafts. This report illustrates a kink in a LIMA graft to the LAD causing an obstructive lesion shortly after surgery and describes the subsequent management of this lesion with intracoronary stents. Cathet. Cardiovasc. Intervent. 46:223–226, 1999. © 1999 Wiley-Liss, Inc.     

'Cold hand, ischemic heart': treatment by stenting of the left subclavian artery

A 59-year-old man presented with worsening angina and a cold, painful left hand, eight years after coronary artery bypass surgery. Coronary angiography showed extensive coronary atherosclerosis with blocked vein grafts to his left circumflex and right coronary arteries. There was a severe narrowing in the left subclavian artery before the origin of the left internal mammary artery (LIMA) which appeared patent. PTCA and stent implantation to the left subclavian artery stenosis restored normal flow to the left hand and the LIMA with abolition of his ischemic hand symptoms and marked improvement of his angina.     

Coronary subclavian steal syndrome: treatment by stenting of the left subclavian artery

A 48-year-old Turkish male presented with worsening angina and a painful left hand eight years after coronary artery bypass surgery. Coronary angiography showed extensive coronary atherosclerosis with patent vein grafts to his diagonal branch and right coronary arteries. There was a severe narrowing lesion in the left subclavian artery before the origin of the left internal mammary artery (LIMA), which appeared patent. Percutaneous subclavian angioplasty and stent implantation to the left subclavian artery stenosis restored normal flow to the left hand and the LIMA with abolition of his ischemic hand symptom and marked improvement of his angina.     

Closure of guide wire-induced coronary artery perforation with a two-component fibrin glue.

Perforation or rupture of a coronary artery with subsequent pericardial effusion and cardiac tamponade is a potentially life-threatening complication of percutaneous coronary intervention (PCI). Several emergency treatment strategies exist to close the perforation including reversal of anticoagulation, prolonged balloon inflation, implantation of stent grafts, local injection of thrombogenic molecules, placement of microcoils, or open heart surgery. Here we report on a 66-year-old patient who underwent urgent PCI for acute stent thrombosis in the proximal LAD. The artery was reopened, a new stent implanted successfully, and a GPIIb/IIIa-antagonist was given. Shortly thereafter the patient suffered from cardiac tamponade requiring pericardiocentesis and pericardial drainage. The coronary angiogram indicated a severe guide wire-induced perforation and pericardial effusion originating from a distal diagonal branch segment. Prolonged balloon inflation did not stop the leakage. Therefore the monorail balloon was exchanged for an over-the-wire balloon. A two-component commercial fibrin glue consisting of fibrinogen and thrombin was rapidly but separately injected through the wire channel of the balloon into the distal segment of the diagonal branch. The coronary leak was successfully closed and the patient recovered quickly. In comparison with the previously reported cases of thrombin injection important differences should be noticed: (1) a two-component hemostatic seal was used without reversal of anticoagulation, (2) rapid injection instead of prolonged infusion of the hemostatic drugs was performed, and (3) the rescue technique was applied in a cath lab that routinely uses monorail catheter systems. Therefore we consider this a novel and effective approach for closure of coronary ruptures.     

Iatrogenic left internal mammary artery-coronary vein anastomosis treated with covered stent deployment via retrograde percutaneous coronary sinus approach.

OBJECTIVES: Percutaneous treatment of acquired coronary fistula with covered stent BACKGROUND: Acquired aorto-coronary fistulae (ACF) is a rare complication of coronary artery bypass graft (CABG) surgery. Surgical repair has been generally recommended, but percutaneous techniques have also been described; coils were used primarily in smaller fistula while double umbrella or vascular occlusion devices were used in larger ones. To the best of our knowledge the use of coronary covered stent has never been reported. A 73-year-old man underwent CABG in November 2004 for unstable angina and left internal mammary artery (LIMA) was anastomosed to left anterior descending (LAD) coronary artery. Three months later he underwent a control angiogram to check for the reappearance of effort angina, which demonstrated an inadvertent LIMA-great cardiac vein (GCV) anastomosis. After discussions, an attempt to close the ACF with implantation of a covered stent was performed. METHODS: Using a percutaneous right internal jugular vein approach, coronary sinus was selectively cannulated and a 0.014-in. coronary guide wire was advanced selectively to the GCV, then a covered stent was deployed across the anastomotic site, obtaining the immediate occlusion of the ACF. RESULTS: No contrast medium flowed into the distal part of the GCV at the reinjection of the coronary sinus and a selective injection into LIMA showed the absence of flow through LIMA, confirming the occlusion of the anastomotic site. CONCLUSIONS: We have demonstrated successful occlusion of an iatrogenic ACF by using percutaneous stenting of GCV with covered stent via coronary sinus approach, which seems to be technically less demanding, safer, and time sparing.     

Hybrid coronary revascularization for the treatment of left main coronary stenosis: a feasibility study

Objective : To determine the feasibility of a hybrid coronary revascularization (HCR) approach for the treatment of left main (LM) coronary artery stenosis. Background : The recommended therapy for significant LM stenosis is coronary artery bypass grafting (CABG). Percutaneous coronary intervention (PCI) of unprotected LM lesions is reserved for patients at high risk for complications with CABG. HCR in LM disease has not been studied. Methods : Twenty‐two consecutive patients with LM stenosis >70% underwent staged HCR. Following a robotic or thoracoscopic‐assisted minimally invasive left internal mammary artery (LIMA) to left anterior descending artery (LAD) coronary bypass, PCI of the LM, and non‐LAD targets was performed after angiographic confirmation of LIMA patency. Intravascular ultrasound confirmed optimal stent deployment. Thirty‐day adverse outcomes and long term follow up was obtained. Results : In the 22 patients with LM lesions, 6 were ostial, 5 mid, and 11 distal. LIMA patency was FitzGibbon A in all cases. LM stenting was successful in all patients with drug‐eluting stents (DES) placed in 21 of 22 cases. Three patients underwent stent implantation in the right coronary artery. There were no 30‐day major adverse cardiac or cerebrovascular events. At a mean of 38.8 ± 22 months postprocedure, 21 patients were alive without reintervention; one death occurred at 454 days. Conclusions : HCR for LM coronary disease is a feasible alternative to CABG and unprotected LM PCI. This approach combines the long‐term durability of a LIMA‐LAD bypass with the less invasive option of PCI in non‐LAD targets with DES. © 2011 Wiley Periodicals, Inc.     

“一站式”复合技术治疗冠状动脉多支病变临床及造影中期随访结果：附42例造影结果分析

目的通过临床和冠脉造影评价＂一站式＂复合技术旁路的中期通畅率及临床疗效。方法 2010.10～2011.12共42例接受＂一站式＂复合技术治疗患者随访观察,所有患者均免于主要心脏或脑血管不良事件（Major adverse cardiac or cerebrovascular events,MACCE）发生的生存率,同时行冠脉造影确认患者左内乳动脉（left internal mammaryar tery LIMA）旁路及非左前降支（left anterior descending artery LAD）靶血管药物支架通畅率。男37例,女5例,年龄64.3±9.6岁,平均随访时间18±8.9个月。结果 42例患者均无MACCE。患者心功能Ⅰ级19例,Ⅱ级23例。冠脉造影结果显示：LIMA旁路42支,狭窄1支,闭塞1支,通畅率95.2%（40/42）。药物支架植入靶血管52支,再狭窄5支。LIMA旁路闭塞后LAD再次支架植入1支,原支架再狭窄再次植入支架病变冠脉2支,再次支架植入治疗冠脉新发病变3支。非LAD病变冠脉通畅率82.7%（43/52）。结论 ＂一站式＂复合技术治疗冠状动脉多支病变患者术后18个月的LIMA-LAD旁路和非LAD靶血管的药物支架具有较高的通畅率,提示一站式复合技术治疗冠状动脉多支病变术后1年通畅率及临床疗效优于文献报道的单纯冠状动脉旁路移植术（Coronary artery bypass graftingCABG）或经皮冠状动脉介入治疗（Percutaneous coronary intervention PCI）的通畅率,其长期效果需要进一步随访。     

Coronary artery perforation during coronary angioplasty

In one patient percutaneous transluminal coronary angioplasty was complicated by coronary artery perforation of the left anterior descending coronary artery with light pericardial effusion. The outcome was favorable without either pericardiocentesis or emergency surgery.