针刺与连续多点脉冲刺激对感觉神经性耳聋患者语言频率听力损失的影响

目的:探讨感觉神经性耳聋的有效治疗手段.方法:将经纯音测试、耳科医师确诊的34例轻中度感觉神经性耳聋患者,按中医辨证分为肝肾不足型(24例)和肝火旺盛型(10例),主穴取耳门、听宫、听会(取其一),翳风、神庭、百会、后顶、头维、聪耳1～3、聪脑1、聪脑2.配穴:肝肾不足型加肓俞、气海、关元、太溪;肝火旺盛型加中脘、天枢、阳陵泉、太冲.使用顺序连续多点脉冲刺激,每周2次,连续20周(40次)后复查纯音测听.结果:34例患者(58只病耳)治愈13例,好转21例;治疗前后各语言频率听阈纯音测听值均有明显提高,其差异有显著性意义(P<0.05).结论:针刺与连续多点脉冲刺激对感觉神经性耳聋患者语言频率听力损失具有确切疗效.     

深刺与浅刺治疗突发性耳聋的疗效观察

目的：探讨及评价不同针刺深度治疗突发性耳聋的疗效。方法：将47例患者随机分为治疗组23例（深刺耳前3穴即耳门、听宫、听会配合体针疗法）；对照组24例（浅刺耳前3穴配合体针疗法），观察和比较治疗后不同时期两组听力变化及伴随症状的变化。结果：治疗组的有效率为87．0％，对照组的有效率为29．2％，经统计学处理，P〈0．05，差异有显著性意义。结论：深刺组疗效优于浅刺组。     

Treatment of sudden deafness by acupuncture plus hyperbaric oxygen

Yifeng (TE 17), Tinghui (GB 2), Zhongzhu (TE 3) and Xiaxi (GB 43) were selected as key acupoints plus hyperbaric oxygen to treat 50 cases of sudden deafness, and the total effective rate was 98%. Author: GUO Min (1971-), female, acupuncturist Translator: WU Xue-fei     

穴位的不同组织特性对电针针感的影响（英文）

目的:评估穴位的组织特性(不同经络、组织、神经节段)对电针针感频率、强度及产生针感电流量的影响。方法:电针针刺21名健康志愿者,根据穴位不同组织特性配成5组:足三里vs阳陵泉(ST 36 vs GB 34,不同经络)、内关vs大陵(PC 6 vs PC 7,不同组织)、足三里vs水道(ST 36 vs ST 28,不同神经节段)、关元vs中脘(CV 4 vs CV 12,不同神经节段)、足三里vs关元(ST 36 vs CV 4,不同组织、经络、神经节段)。电针频率为15 Hz,电流量以受试者能忍受但不产生尖锐性疼痛为度,间断电针3次,通电时间共90 s。记录酸感、麻木、胀满、沉重、麻刺、压感、钝痛、热感及冷感针感和产生针感的电流量,比较配对穴位间各种针感发生的频次、强度及电流量间的差异。结果:各种针感频次在配对穴位间差异均无统计学意义(均P>0.05),电针针刺的9种感觉中,胀满、麻木和酸感最常见和最明显,沉重、压感和麻刺次之,钝痛、热感和冷感的发生频次均较低;部分针感强度在配对穴位间存在差别,酸感、胀满、沉重感在ST 36较ST 28更强(均P<0.05),胀满、麻木在ST 36较CV 4更明显(均P<0.01),胀满在CV 4较CV 12更明显(P<0.05);电针针刺电流量在配对穴位间相近(均P>0.05)。结论:在产生针感的电流量未见明显差异的状态下,电针针感次数与穴位的不同组织间未见明显相关,穴位间针感强度的差异可能与穴位位于不同神经节段相关。不同时间电针刺激同一穴位产生的各针感频次及其强度具有相对稳定性。     

以自控无创电刺激穴位治疗为主的两阶段序列疗法治疗单侧难治性原发性耳鸣的探究＊

目的 探讨以自控无创电刺激穴位治疗为主的两阶段序列疗法对单侧难治性原发性耳鸣的治疗效果。方法 选择单侧难治性原发性耳鸣患者42例，利用研究者发明的基于智能手机和蓝牙通信控制的耳鸣经络穴位治疗仪分别对听宫穴-翳风穴，听宫穴-中渚穴以及翳风穴-中渚穴三组穴位依次进行自控电刺激治疗，2周一个疗程，共治疗2个疗程。第一疗程后，加用激素治疗1周，同时进行改善微循环治疗2周。采用耳鸣严重程度评估量表于治疗第2周、第4周、治疗结束后1个月及3个月进行疗效评估。结果 治疗2周后，4例痊愈，3例显效，17例有效，18例无效，总有效率57.14%。治疗4周后6例痊愈，8例显效，16例有效，12例无效，总有效率71.43%。所有治疗过程中无听力减退、失眠、局部损伤等副作用。治疗结束后1月，6例痊愈，8例显效，16例有效，12例无效，总有效率71.43%；治疗结束后3月，4例痊愈，7例显效，15例有效，16例无效，总有效率61.90%；治疗结束1月和3月的随访过程中，均无患者反映治疗过程中及治疗结束后有听力减退、局部损伤等任何副作用。结论 以自控无创电刺激穴位治疗为主的两阶段序列疗法是一种安全、便捷、有效的耳鸣治疗方法，可以惠及耳鸣患者，具有广阔的应用前景。     

阴虚体质任脉线上体表温度、循经红外辐射轨迹特征及电针对其的影响

目的:观察自然状态下平和、阴虚体质任脉线上体表温度、循经红外辐射轨迹特征(IRRTM),并探讨电针对其的影响。方法:应用红外热像仪观察17名阴虚体质受试者电针前后任脉体表温度、IRRTM并与平和体质进行比较。结果:在自然状态下:阴虚体质任脉上平均体表温度,膻中穴、下脘穴、气海穴体表均高于平和体质,其中膻中穴具有显著性差异(P<0.05);平和质3个穴位进行比较,膻中穴体表温度显著高于下脘穴与气海穴(P<0.01);阴虚体质3个穴位进行比较,膻中穴体表温度显著高于气海穴(P<0.05);平和体质组IRRTM显示的连续性更好、范围更长;阴虚体质组IRRTM显示范围较宽,与周边组织分界不如平和体质组清晰。电针中脘穴20min:与本组自然状态同穴位比较,平和体质下脘穴体表温度显著升高(P<0.05);阴虚体质下脘穴体表温度显著降低(P<0.05)。电针可诱发平和体质任脉IRRTM轨迹变长,而对已能显示任脉IRRTM轨迹的受试者,电针则可使其变得连续、规整;电针可使部分阴虚体质受试者任脉IRRTM轨迹出现与任脉循经红外辐射轨迹走向相同的低温线,分布在膻中穴周围。结论:阴虚体质任脉上体表温度高,在膻中穴上明显;电针中脘穴能升高平和体质下脘穴体表温度,却降低阴虚体质下脘穴体表温度;表明针刺对不同体质受试者IRRTM能产生不同的影响,IRRTM与人体的能量代谢有密切的关系。     

电针保护大鼠急性胃黏膜损伤基本腧穴配伍“胃病方”的筛选

目的:通过对临床治疗胃病最常用的3个腧穴不同组合配伍的效应比较,选出最优的穴位组合。方法:将48只清洁级Wistar大鼠按析因设计随机分为8组,即模型组、足三里组、中脘组、内关组、足三里+中脘组、足三里+内关组、中脘+内关组、足三里+中脘+内关组。采用无水乙醇灌胃法制作急性胃黏膜损伤模型。除模型组外,其它组大鼠在相应穴位施以电针。电针治疗结束1 h后,取大鼠的胃黏膜组织,分别进行胃溃疡指数的计算、组织学观察,并运用透射电镜进行超微结构观察。结果:7个电针组与模型组相比,胃黏膜损伤指数和病理损伤积分显著降低(P<0.05)。足三里+中脘+内关组与其它6个电针组相比,两项指标降低更显著(P<0.05)。超微结构观察见模型组胃黏膜壁细胞、主细胞内线粒体肿胀,嵴排列紊乱、断裂,甚至溶解;各电针组胃黏膜细胞损伤程度减轻,足三里+中脘+内关组更为明显。结论:同时电针"足三里"内关"和"中脘"减轻胃黏膜损伤的作用优于其单穴或双穴使用,因而可作为治疗胃病的基本处方。     

“标本配穴”电针对早期糖尿病肾病患者血液流变学及内皮型一氧化氮合酶的影响

目的:观察"标本配穴"电针疗法对早期糖尿病肾病(DKD)患者肾功能、血液流变学和内皮型一氧化氮合酶(eNOS)水平的影响,探讨"标本配穴"电针对早期DKD的保护作用及机制。方法:选取120例早期DKD患者,随机分为西药组、常规组、标本配穴组,每组40例。西药组予常规控制血糖、血压、血脂治疗;在西药组治疗的基础上,标本配穴组根据"标本配穴"法电针"标"穴中脘、丰隆、血海、太冲及"本"穴关元、足三里,常规组电针双侧肺俞、胃脘下俞、胃俞、肾俞、三阴交、太溪。各组均治疗1次/d, 5 d/周,共治疗8周。分别于治疗前后采用全自动特异性蛋白质分析仪检测各组患者24 h尿微量白蛋白排泄率(UAER);全自动生化分析仪检测血清肌酐(Scr)、尿素氮(BUN)、胱抑素(CysC)含量;全自动血流变测试仪检测全血低切黏度(ηbL)、全血中切黏度(ηbM)、全血高切黏度(ηbH)、血浆黏度(ηp)和纤维蛋白原(FIB)水平;酶联免疫吸附试验测定血清eNOS和一氧化氮(NO)水平。比较各组治疗的总有效率并观察其不良反应。结果:与本组治疗前比较,3组患者治疗后UAER及血清Scr、BUN、CysC,ηbL、η...     

偏头痛发作期针刺镇痛方案优选研究

目的:对偏头痛发作期针刺镇痛方案进行优选,指导偏头痛针灸临床决策。方法:以76例发作期偏头痛患者为研究对象,采用正交试验设计,治疗方案根据L9(34)正交表对体穴组合(A)、毫针及电针疗法(B)、耳穴疗法(C)、放血疗法(D)4因素及其各自不同的3水平设计实施。试验过程中同时应用了随机(分层随机、中心随机)和盲法(评价者盲)的方法。采用视觉模拟评分法(VAS)测量头痛强度,根据治疗前及治疗后10min、20min、30min、1h、2h、3h、4h、5h、6h、12h、24h共计12个时点的VAS值变化情况,对不同针刺方案的镇痛效果进行分析。结果:针刺后24h内,4因素对缓解头痛强度的影响由大到小依次为:体穴组合(A)>毫针及电针疗法(B)>放血疗法(D)>耳穴疗法(C)。由正交推导出来的不同时点最佳针刺镇痛方案中,少阳经局部加远端取穴进行毫针刺的疗效最稳定,可作为基础镇痛方案;耳穴电针有助于提高即刻镇痛效果;太阳紫脉加阿是穴放血可巩固镇痛效果。结论:偏头痛发作期最佳针刺镇痛方案为少阳经为主局部加远端取穴进行毫针刺,同时配合耳穴电针以及太阳紫脉和阿是穴放血。     

电针治疗肠黏膜损伤大鼠基本腧穴配伍“肠病方”的筛选

目的:选用临床治疗肠病最常用的3个腧穴即中脘、天枢、上巨虚,通过观察不同组合配伍的效应,选出最优的穴位组合。方法:SD大鼠126只,按随机数字表分为空白组、模型组、中脘组、天枢组、上巨虚组、中脘+上巨虚组、天枢+上巨虚组、中脘+天枢组、中脘+天枢+上巨虚组。采用8%冰乙酸灌肠法造模。各治疗组在相应穴位施以电针,每日1次,共治疗3次。治疗结束后,分别观察各组大鼠的结肠黏膜损伤指数、病理学损伤积分及超微结构变化。结果:与空白组相比,模型组结肠黏膜损伤指数显著降低(P<0.05),病理学损伤积分显著升高(P<0.05);7个电针组与模型组比较,结肠黏膜损伤指数显著升高(P<0.05),病理学损伤积分显著降低(P<0.05);天枢+中脘+上巨虚组与其它6个电针组相比,两项指标变化更显著(P<0.05)。超微结构观察表明,各电针组结肠黏膜损伤程度较模型组减轻,天枢+中脘+上巨虚组更加明显。结论:同时电针"中脘"天枢"上巨虚"减轻结肠黏膜损伤的作用优于其它单穴或双穴使用,因而可作为治疗肠病的基本处方。     

Repeated Application of Electroacupuncture Ameliorates Hyperglycemia in Obese Zucker Diabetic Fatty Rats

Electroacupuncture (EA) was investigated for lowering the blood glucose (BG) in fasting male obese Zucker fatty diabetic (ZDF) rats aged 10–17 weeks. Anesthesia provided satisfactory chemical restraint to enable repeated EA. Animals in Groups 1, 2 and 3 were anesthetized on Days 1, 3, 5, 8, 10 and 12. Group 1 (n = 4) received no EA (controls), Group 2 (n = 4) EA at Zhongwan and Guanyuan acupoints, and Group 3 (n = 4) EA at both Zusanli acupoints. BG was measured at 10 and 20 minutes, and EA was applied for 30 minutes, after which BG was measured again. Group 2 had a significantly lower baseline BG at 20 minutes on Days 5, 8 and 12 and significantly less change in BG over 30 minutes on Days 3 and 5 than Group 1 (p < 0.05). Group 3 showed a significant decrease in the mean baseline BG compared to Group 1 in Week 1 (p < 0.05). Thus, repeated EA using Zhongwan and Guanyuan acupoints was effective in lowering the baseline BG and modulating the change in the BG in anesthetized animals.     

Antinociceptive effects of heterotopic electroacupuncture in formalin-induced pain

This study examined the antinociceptive effect of electroacupuncture (EA) to heterotopic acupoints on formalin-induced pain in rats. EA (2 ms, 10 Hz, and 3 mA) was delivered to heterotopic acupoints HE(7) and PE(7), or non-acupoints at the right fore limb, for 30 min and was immediately followed by subcutaneous formalin injection into the left hind paw, respectively. The quantified pain score, electromyogram (EMG) response of the C-fiber reflex, and cFos immunoreactivity were assessed, respectively. EA to heterotopic acupoints significantly reduced both early- and late-phase pain-like behaviors and significantly decreased the EMG responses of the C-fiber reflex after formalin injection. By contrast, EA to non-acupoints had no significant effects on pain-like behavior or the EMG response. In addition, EA to heterotopic acupoints decreased cFos immunoreactivity in the lumbar spinal dorsal horn. Therefore, EA induced pre-emptive antinociception via the extra-segmental inhibition of the formalin-induced pain, suggesting that EA to heterotopic acupoints is a useful treatment for inflammatory pain.     

不同疗法治疗突发性耳聋疗效观察

目的:在多种针灸治疗方法中寻找治疗突发性感音神经性耳聋的最佳疗法.方法:将187例患者随机分为针刺组(A组)、电针组(B组)、针刺加穴位注射组(C组)、电针加穴位注射组(D组),穴取患侧耳门、听宫、听会、翳风、风池,头部上星、百会、四神聪,体穴合谷、外关等.每日治疗1次,经治疗40次后再次进行听力测试,并对比疗效差异.结果:各组总有效率分别为A组47.6%、B组79.2%、C组76.0%、D组94.0%,D组疗效最好,A组疗效最差,D组与其他各组比较差异均有统计学意义(均P<0.05).在D组中,发病在2周之内的患者针刺疗效优于2周以上的患者(P<0.05);轻中度患者针刺疗效优于重度患者(P<0.05);年龄在50岁以下的患者针刺疗效优于50岁以上的患者(P<0.05).结论:电针加穴位注射是治疗急性突发性感音神经性耳聋的最佳疗法,同时观察到针灸的及时干预、病情的轻重程度、患者年龄都关系到本病的预后.     

58 CASES OF PROSTATIC HYPERTROPHY TREATED BY ELECTROACUPUNCTURE

In the present paper, 58 prostatic hypertrophy patients were treated with electroacupuncture (EA) therapy. Their ages ranged from 50 to above 70 years in 38 cases and above 80 years in 20 cases. Main acupoints were Qugu (CV 2), Henggu (KI 11), Shuidao (ST 28) and Guanyuan (CV 4) in combination with auxiliary acupoints Zhonglushu (BL 29), Huiyang (BL 35) and Sanyinjiao (SP 6) which were stimulated with EA Therapeutic Apparatus for 30min. After treatment, of the 58 cases, 36 were cured, accounting for 62 %, 20 had marked effect, accounting for 34%, and 2 had no any effectiveness, accounting for 3%. The total effective rate was 96%.     

林国华针灸治疗难治性突发性耳聋经验撷要

总结林国华教授针灸治疗难治性突发性耳聋经验,并对典型医案进行介绍.林国华教授认为本病多因少阳经气厥塞所致,提倡尽早针灸干预,治病求本,谨守"少阳暴厥"之病机,谨遵"疏解少阳,通耳开窍"之法,临证必用听宫,主取少阳经穴,辅予辨经取穴,巧施发蒙针法与气流灌耳法,妙用岭南火针疗法,必要时调气调神、加取募穴,共奏通耳复聪之效.     

Study of electroacupuncture with different frequencies for the treatment of headache and anxiety-depression symptoms in patients with migraine: A randomized clinical trial: 不同频率电针改善偏头痛患者头痛及焦虑抑郁症状的差异性研究-随机临床试验

ObjectiveTo observe the effects of electroacupuncture (EA) with varied frequencies on headache and anxiety-depression symptoms in patients with migraine and to screen optimal frequency of EA for patients with such conditions.DesignSingle-center, randomized, controlled clinical trial was designed, and the outcome assessors and statisticians were blinded. The patients with migraine were randomized into 2 Hz EA group, 100 Hz EA group and sham-stimulation group. In each group, the changes in migraine attacks, days with headache, the scores of visual analogy scale (VAS), self-rating anxiety scale (SAS), self-rating depression scale (SDS) and migraine-specific quality-of-life questionnaire (MSQ), as well as the dosage of analgesics were observed at the baseline, during treatment, in 1, 2 and 3 months of follow-up separately.SettingPatients were enrolled in the Third Affiliated Hospital of Zhejiang Chinese Medical University, between 1^st August 2018 and 31^st July 2021.ParticipantsSixty-five migraine patients with or without aura.InterventionsIn the EA groups, the acupoints were bilateral Fengchi (GB20), Gongxue (Extra), Sizhukong (TE23), Taiyang (EX-HN5), Shuaigu (GB8), Waiguan (TE5) and Yanglingquan (GB34). Electric stimulation was exerted at GB20 and Gongxue (Extra), with 2 Hz and 100 Hz separately. In the sham-stimulation group, the shallow acupuncture was operated at the sites 1 cm lateral to GB20 and Gongxue (Extra), and on the radial side of TE5 and GB34. The output wires were cut off after attached to the acupoints. The patients in each group received the treatment 3 times weekly, once every two days, for consecutive 4 weeks. The complete intervention was composed of 12 treatments.Main outcome measuresChanges in numbers of migraine attacks at treatment phase (week 1 to week 4) from the baseline(week -4 to week 0) in patients of each groupResults(1) Changes in migraine attacks and days with headache: In the 2 Hz EA and 100 Hz EA groups, the changes for migraine attacks and days of headache were higher significantly when compared with that in the sham-stimulation group at the same time stage (P < 0.05). There was no statistical difference between two EA groups. (2) Changes of VAS score: In the 2 Hz EA and 100 Hz EA groups, the changes of VAS score were significantly higher when compared with that in the sham-stimulation group at the same time stage (P < 0.05). There was no statistical difference between two EA groups. (3) Assessment of anxiety and depression: The differences in the changes of SAS and SDS scores had no statistical significance in patients of each group at each assessment stage (P > 0.05). (4) Assessment on the quality of life: Compared with the sham-stimulation group at the same time stage, the improvement in MSQ score was increased significantly during treatment in patients of the 2 Hz EA and 100 Hz groups (P < 0.05). There was no statistical difference between two EA groups. (5) Assessment on safety and compliance: The patients of each group had sound compliance. There was no adverse events during trial, suggesting promising safety of treatment.ConclusionEA may effectively reduce the migraine attacks, and the days and intensity of headache, presenting promising safety. However, there was no significant improvement on anxiety-depression symptoms, and no significant difference between high and low frequencies of EA treatment in relieving headache and anxiety/depression symptoms in the patients with migraine.Trial registrationChiCTR1800017259     

针刺眼三针对Bell麻痹疗效的影响

OBJECTIVE: To probe the effect of acupuncture at three acupoints of eye on Bell palsy. METHODS: Seventy-six cases were randomly divided into a routine acupuncture group and a Yan three needling group, 38 cases in each group. The routine acupuncture group were treated with electroacupuncture (EA) at routinely selected acupoints including Yifeng (TE 17), Dicang (ST 4), etc. and the Yan three needling group were treated by EA at the routinely selected acupoints combined with acupuncture at three acupoints of eye including Jingming (BL 1), Shangming, Chengqi (ST 1). The intensity on 0.05 ms in the intensity/time (I/t) curve for frontal ventral fronto-occipital muscle and orbicular muscle of mouth at the affected side was used for assessment criteria of course of disease, and frontal ventral fronto-occipital muscle restoring the raising eyebrow action and orbicular muscle of mouth restoring to House-Brackmann grade I and II were regarded as the therapeutic time limit. RESULTS: Routine EA treatment combined with acupuncture at the 3 acupoints of eye could significantly increase clinical therapeutic effect on Bell palsy with a cured rate of 89.5%, which was better than 65.8% in the routine acupuncture group (P<0.05), and the therapeutic cycle was shorted. CONCLUSION: Acupuncture at the 3 acupoints of eye can significantly improve Bell palsy and promote recovery of functions of facial nerves.     

Analysis of Acupuncture Treatment Characteristics of Insomnia in Ancient Times

运用计算机对93种古医籍中用针灸治疗失眠的内容进行统计,统计结果显示,古代治疗本证共涉及穴位65个,总计108穴次.常用穴位为公孙、胆俞、隐白、气海、天府、三阴交、阴陵泉、肺俞、液门、关元、阴交等.常用经络为膀胱经、脾经、任脉、胃经等.     

针刺手厥阴经穴对心肌缺血再灌注损伤线粒体超微结构的影响

目的:观察针刺手厥阴经“内关”“郄门”穴在缺血再灌注损伤过程中对线粒体超微结构的影响,阐明电针手厥阴经穴对心肌缺血再灌注损伤的作用机理。方法:Wistar大鼠50只,分为假手术组、缺血再灌注模型组、针刺“内关”治疗组、针刺“郄门”治疗组和针刺“支沟”对照组。在大鼠冠状动脉左前降支根部穿线,电针大鼠穴位20 min后,造模组结扎冠状动脉左前降支40 min,心电图监测,再电针穴位20 min,松扎,恢复灌流60 min,摘取心脏,透射电镜下观察心肌组织线粒体的超微结构变化。结果:缺血再灌注模型组心电图ST段抬高明显,与针刺“内关”及针刺“郄门”治疗组比较差异均有显著性意义(P<0.05),“支沟”组ST段变化趋势与模型组近似,二者比较无显著性差异(P>0.05)。模型组线粒体内室水肿、空泡变,嵴减少,形成较宽的电子透亮区。“内关”及“郄门”治疗组嵴排列整齐,仅见部分线粒体轻度水肿。结论:电针手厥阴经穴可明显减轻线粒体超微结构的病理变化,在一定程度上对缺血再灌注损伤心肌起到了保护作用。     

针药结合治疗泌尿系结石

1996～ 1 999年收治泌尿系结石 1 2 2例 ,其中肾结石 36例 ,输尿管结石 86例 ;男性 80例 ,女性42例 ;年龄最大 6 5岁 ,最小 9岁 ;病程最长 2 0年 ,最短 3天 ;肾绞痛发作者 42例。所有病例均经过Ｂ超检查 ,部分病例做了肾造影和腹平片 ,结石最大者 1 0ｍｍ× 1 0ｍｍ ,最小者 3ｍｍ× 4ｍｍ。以中医理论为指导 ,采用针灸与药物相结合的治疗方法。 (1 )针灸取穴及治法 :主穴分为两组 :①肾俞、京门、阳陵泉、飞阳 ;②关元、水道、阴陵泉、三阴交等 ,两组穴位交替使用 ,每日 1次 ,每次留针30ｍｉｎ。对不同症状分别辅以配穴 :肾绞痛取耳穴神门…