脑梗死患者焦虑、抑郁的调查分析及干预

目的 研究脑梗死患者住院期间的心理状态,为脑梗死患者临床心理护理提供依据.方法 采用焦虑自评量表(SAS)及抑郁自评量表(SDS),对70例脑梗死患者(实验组40例和对照组30例)进行调查,对调查结果进行统计学分析,并对实验组进行护理干预.结果 70例患者中,焦虑自评量表得分>50分者27例(38.6%),抑郁自评量表得分>50分者33例(47.1%),实验组护理干预前后SAS及SDS评分变化差异具有统计学意义(P<0.05,P<0.01);2组SAS及SDS变化差异也有统计学意义(P<0.05,P<0.01).结论 焦虑与抑郁是脑梗死患者住院期间的常见心理障碍,对患者的躯体症状进行积极治疗的同时,应加强其心理护理,从而促使患者尽快康复.     

住院精神分裂症患者亲属SAS及SDS测评结果分析

目的探讨住院精神分裂症患者亲属焦虑、抑郁状况。方法采用焦虑自评量表（SAS）及抑郁自评量表（SDS），对100例住院精神分裂症患者亲属在患者入院及住院第4周时追行两次测评。结果首次SAS，SDS测评显示，所有亲属得分均显著高于全国常模（P〈0.001）；第二次测评显示，父母SAS及配偶SAS、SDS得分均明显高于全国常模（P〈0.01）；SAS及SDS减分率依次为：其他亲属〉父母〉配偶。结论住院精神分裂症患者亲属存在明显的焦虑、抑郁症状，应积极开展健康教育活动，给予必要的心理支持及药物干预。     

支持性护理干预改善心血管神经症患者焦虑和抑郁的效果

目的：分析支持性护理干预改善心血管神经症患者焦虑和抑郁的效果。方法采用随机数字表法将105例确诊心血管神经症患者进行分组,对照组52例行心内科常规护理干预,观察组53例在对照组基础上行支持性护理干预,连续干预30 d后,采用Zung焦虑自评量表（SAS评分）和抑郁自评量表（SDS评分）对比护理干预效果。结果观察组干预后总有效率96.23％明显高于对照组84.62％（P＜0.05）;2组均能够降低SAS评分和SDS评分,但观察组降低SAS评分和SDS评分幅度明显高于对照组（ P＜0.01）。结论支持性护理干预能够改善心血管神经症患者焦虑和抑郁障碍,促进患者的早期康复,在提高生存质量和促进患者早期康复方面具有积极的作用。     

医院女职工心理健康状况调查

目的 了解医院女职工的心理健康状况.方法 采用身心症状自评量表 (Smptom Cheklist 90,SCL-90)、ZUNG氏焦虑自评量表(SAS)和ZUNG氏抑郁自评量表(SDS)调查了杭州市第一人民医院301名在职女职工.结果 女职工SCL-90的躯体化、抑郁、焦虑因子分高于国内正常人水平(P＜0.05),而人际关系因子分低于国内正常人水平(P＜0.05),其他因子分与国内常模比较差异无显著性,SCL-90、SAS和SDS的各因子分在各个年龄段的比较差异无显著性.结论 医院女职工心理健康状况较差,低于一般普通人群,有必要对她们进行适当的心理干预.     

心理干预对急性心肌梗死患者焦虑抑郁的作用

目的心理干预对急性心肌梗死患者焦虑、抑郁情绪的影响。方法将82例急性心肌梗死患者随机分为干预组43例和对照组43例,在常规治疗基础上,干预组进行心理护理干预,对照组采用传统护理方法。2组均在入院后及治疗3周后分别采用焦虑自评量表(SAS)和抑郁自评量表(SDS)测试病人治疗前后的焦虑、抑郁程度。观察2组病人治疗前后焦虑、抑郁程度及医患依从性情。结果心理干预前干预组和对照组患者SAS、SDS评分无显著性差异(P>0.05);心理干预3周后干预组患者SAS、SDS评分与干预前比较差异有统计学意义(P<0.05),对照组差异无统计学意义(P>0.05);心理干预3周后干预组与对照组患者SAS、SDS评分比较差异有统计学意义(P<0.05)。结论心理干预有利于急性心肌梗死患者的身心健康,可有效缓解焦虑、抑郁情绪,提高临床疗效。     

积极心理干预对住院精神分裂症患者家属负性情绪的影响

目的探讨积极心理干预对住院精神分裂症患者家属负性情绪的影响,寻找改善家属负性情绪的方法。方法选择2014年11月-2016年9月符合《国际疾病分类(第10版)》(ICD-10)精神分裂症诊断标准的住院患者家属为研究对象,共68名。采用随机数字表法分为对照组和研究组各34名。两组均给予常规健康教育,研究组在此基础上进行积极心理干预3个月。两组在入组前以及干预3个月末分别接受焦虑自评量表(SAS)、抑郁自评量表(SDS)、简易应对方式量表(SCSQ)评定。结果①入组时两组SAS、SDS和SCSQ评分差异均无统计学意义(P均0.05);②干预3个月末研究组SAS和SDS评分均低于对照组,差异有统计学意义(P均0.01);③研究结束时,研究组SCSQ积极应对方式评分高于对照组。结论积极心理干预可能有助于改善精神分裂症患者家属的焦虑及抑郁负性情绪。     

首发精神分裂症患者父母的心理状况及干预

目的探讨首发精神分裂症患者父母的心理卫生状况.方法对112例患者父母采用精神症状自评量表(SCL-90)及焦虑自评量表(SAS)抑郁自评量表(SDS)进行测评,并根据测评存在的心理问题给予不同层次干预.结果首发精神分裂症父母存在明显焦虑抑郁情绪,SCL-90、SAS、SDS评分明显高于国内常模.母亲不良情绪反应较父亲重,经心理干预改变观念,及病人病情逐渐好转后,患者父母SAS、SDS评分也随之下降.结论首发精神分裂症父母存在着不同程度心理问题,应主动做好他们的心理干预,提高他们的心理承受能力,减轻心理应激反应程度.     

首发精神分裂症患者亲属的心理状况及干预效果探讨

目的　探讨首发精神分裂症患者亲属的心理状况及干预效果。方法　对 5 0例首发精神分裂症患者亲属采用精神症状自评量表 (SCL - 90 )、焦虑自评量表 (SAS)及抑郁自评量表 (SDS)进行测评 ,并根据测评存在的心理问题给予干预。结果　首发精神分裂症患者亲属SCL - 90、SAS、SDS评分明显高于国内常模 ,存在明显的焦虑抑郁情绪 ,男女之间差别不明显 ,经心理干预 ,以及随着患者病情改善 ,患者亲属SAS、SDS评分也随之下降。结论　首发精神分裂症患者亲属存在着不同程度心理问题 ,应主动做好他们的心理干预 ,提高他们的心理承受能力 ,减轻心理应激反应。     

心理干预辅助治疗老年原发性高血压80例疗效观察

目的观察心理干预辅助治疗老年原发性高血压的疗效。方法将80例老年原发性高血压病人通过随机数字表法随机分为2组。干预组40例,给予卡托普利、硝苯地平,在此基础上再给予心理干预;对照组40例,只给予卡托普利和硝苯地平。2组均治疗3周并采用焦虑自评量表(SAS)和抑郁自评量表(SDS)测试病人治疗前后的焦虑、抑郁程度。结果心理干预3周后干预组患者SAS、SDS标准分与干预前比较有显著性差异(P<0.05),对照组无显著性差异(P>0.05)。结论原发性老年高血压患者在使用药物治疗的同时给予适当的心理干预有利于患者的身心健康,可有效缓解焦虑、抑郁情绪,提高临床疗效。     

首发精神分裂症患者配偶的心理状况与心理干预

目的探讨首发精神分裂症患者配偶的心理状况及干预效果。方法对80例首发精神分裂症患者配偶给予症状自评量表（SCL-90）,焦虑自评量表（SAS）,抑郁自评量表（SDS）进行测评,并根据测评存在的心理问题给予干预。结果首发精神分裂症患者配偶SCL-90各因子分,SAS、SDS评分明显高于国内常模,妻子与丈夫间差异不明显。经心理干预及随病情改善,患者配偶SAS、SDS分也随之下降。结论首发精神分裂症患者的配偶存在不同程度的心理问题,心理干预可提高其心理承受能力,减轻心理应激反应。     

Influence of abciximab on the adhesion of platelets on a shielded plasma gradient prepared on polyethylene

INTRODUCTION: Thrombotic effects of biomaterial implants are mediated merely through activation of the platelet glycoprotein IIb-IIIa (GpIIb-IIIa) receptor. Consequently, platelet GpIIb-IIIa receptor inhibitors are successfully used during stent implantation procedures to prevent thrombosis. However, currently a new generation of stents contains surface coating, which changes the surface to more hydrophobic or hydrophilic. This change markedly affects the interaction of platelets and may influence the efficiency of GpIIb-IIIa inhibitors. MATERIALS AND METHODS: To study the influence of the wettability of biomaterials on the effectiveness of abciximab, 5-cm polyethylene gradients with contact angles of 100 degrees to 40 degrees were made by means of glow discharge. Fresh whole blood with or without abciximab was recirculated over this gradient. RESULTS: Inhibition of platelet adhesion by abciximab was maximal, but not complete, on the hydrophobic and moderate hydrophobic part of the gradient, with contact angles of 55 degrees to 90 degrees. Percentage inhibition by abciximab was maximal around 60 degrees. CONCLUSIONS: Intermediate hydrophobicity of currently applied stent materials, such as stainless steel, seems optimal in combination with abciximab. However, on hydrophobic and particularly on hydrophilic materials, abciximab is less effective.     

Laser therapy on points of acupuncture on nerve repair

正Paresthesia is the name given to a temporary or permanent sensory loss caused by several surgical procedures that affected the peripheral sensory nerve.In dentistry,common iatrogenic procedures that can lead to sensory loss include third molar removal,blocking of the inferior alveolar nerve     

Effects of lorazepam on rate of forgetting,on retrieval from semantic memory and on manual dexterity

Using a double-blind procedure, 16 out of 32 volunteer subjects (students) each took 2.5 mg of lorazepam (Ativan) orally and the remainder took a placebo. To overcome the problem of wide variation in individual tolerance to the drug, impairment on a task unrelated to memory (a manual dexterity task) was used to divide drug subjects into a group appreciably affected by the drug. subgroup 1, and a group minimally affected, subgroup 2. Only subgroup 1 showed consistent impairment of episodic memory. Both subgroups showed some impairment in a semantic memory task (generation of words from a specified category), but this was confined to the rate at which the task was carried out. The main aim of the experiment was to examine the effect of lorazepam on the rate of forgetting of word lists when drug and control subjects' initial recall levels were equalized. There was no evidence that the drug affected rate of forgetting: this suggests that it does not affect retention. There was also no evidence that it affected retrieval, since there was no impairment in the recall of material presented before administration of the drug. Hence its locus of action is attributed to input, specifically to impaired encoding of contextual information.     

不同病房模式对精神分裂症病情影响的研究

目的探讨不同病房模式对首发精神分裂症患者病情的影响及康复情况。方法开放式病房的患者为研究组68例,同时选择住封闭式病房患者为对照组130例,对两组患者的临床资料进行比较分析。结果对照组患者入院时焦虑抑郁及敌对猜疑出现明显变化（P＜0.05）;研究组患者在第1周时焦虑抑郁已经开始改善,第2周时病情、阳性症状、一般精神病理、敌对猜疑、激活性也出现明显变化（P＜0.05）;第4周时研究组病情及各因子、认知功能及自知力显著改善,与对照组比较存在统计学差异（P＜0.05）。结论开放式病房模式可以减少患者的负性影响,更快改善患者的认知功能,有利于患者自知力的恢复,使患者的病情达到更全面的康复。     

Efficacy of milnacipran on poststroke depression on inpatient rehabilitation

Post-stroke depression (PSD) has a negative impact on rehabilitation following stroke. No satisfactory antidepressant treatment for PSD has yet been developed. The present study examined the effect of milnacipran, a serotonin and norepinephrine reuptake inhibitor, on PSD patients. Eleven PSD patients taking milnacipran in a rehabilitation hospital were compared to age-matched, sex-matched, and severity of depression at admission-matched PSD patients hospitalized during 2001 who did not take any antidepressant as historical control. Severity of depression was measured using self-rating depression scale for depression (SDS) assessed at admission and discharge after 3 months inpatient rehabilitation. Activities of daily living (ADL) and quality of life (QOL) were measured, respectively, by the functional independence measure (FIM) and a self-completed questionnaire for QOL (QUIK) as outcomes of rehabilitation. For the SDS score, the group taking milnacipran showed significant improvement compared to the control group in our study. FIM was improved in both groups. In the end QUIK did not change significantly in either group. We found no major side-effects of milnacipran among the patients. These results suggest that milnacipran is a safe and effective treatment for PSD for inpatients undergoing rehabilitation.     

Certain predictions on the effectiveness of l-DOPA on parkinsonism

Summary Sixty nine patients with Parkinson's disease were treated with L-DOPA for more than a year. L-DOPA produced remarkable improvement in akinetic patients, moderate improvement in rigidity and slight improvement in tremor. The degree of improvement in akinesia, rigidity and tremor tended to be reversely related to the severity of the disease. Rigidity and akinesia improved better in young patients, but there was no correlation between age and the response of tremor to the treatment. Except for rigidity there was no correlation between the improvement and the duration of the disease.

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Zusammenfassung 69 Parkinsonpatienten wurden während mehr als 1 Jahr mit L-DOPA behandelt. Es wurde dadurch bei akinetischen Patienten eine beachtliche, bei Patienten mit Rigor eine mäßige und bei Patienten mit Tremor eine geringfügige Besserung erreicht. Das Ausmaß der Besserung war in allen drei Formen um so geringer, je ausgeprägter die Symptome bei Behandlungsbeginn waren. Rigor und Akinesie sprachen bei jungen Patienten besser auf die Therapie an, aber es bestand keine Korrelation zwischen dem Alter der Patienten und der Beeinflußbarkeit des Tremors durch die L-DOPA-Therapie. Außer für den Rigor bestand keine Korrelation zwischen dem Ausmaß der Besserung und der Dauer der Erkrankung vor Behandlungsbeginn.