心力衰竭患者焦虑抑郁症状及其相关因素

目的:观察心力衰竭患者焦虑症状(焦虑)和抑郁症状(抑郁)的发生情况及其相关因素. 方法:横断面研究.顺序入选心力衰竭住院患者684例,收集患者的一般资料和住院期间情况,填写Zung氏焦虑自评量表(Self-Rating Anxiety Scale,SAS)和抑郁自评量表(Self-Rating Depression Scale,SDS),进行统计学分析,评价心力衰竭患者焦虑、抑郁的评分情况及其相关因素. 结果:684例心力衰竭患者中有20.03%的患者存在焦虑,有23.39%的患者存在抑郁.性别和文化程度与心力衰竭患者合并焦虑相关(P均<0.05),性别和纽约心功能分级与心力衰竭患者合并抑郁相关(P均<0.05). 结论:心力衰竭患者中存在较高的焦虑和抑郁的发生率;女性、文化程度低的患者更易发生焦虑,女性、心功能分级高的患者更易发生抑郁.     

重庆地区高血压患者并发焦虑抑郁的相关性因素调查

目的:观察重庆市高血压患者中焦虑抑郁的发生情况及焦虑抑郁的相关因素。方法:对重庆市的536例高血压患者进行随机整群抽样调查,填写焦虑自评量表(SAS)和抑郁自评量表(SDS),并进行统计学分析。结果:高血压患者的焦虑与抑郁的发生率显著高于对照组,量表评分显著高于对照组和国内常模。女性、脑力劳动者、分居、离异或丧偶者,业余不参加体育锻炼者,3级高血压患者的SAS评分更高。逐步回归分析显示,收缩压、性别、劳动类型、体育锻炼情况与焦虑抑郁相关。结论:重庆地区高血压患者并发焦虑抑郁的情况严重,且与多种因素相关。     

女性性传播疾病高危人群焦虑自评量表分析

目的　了解性传播疾病高危人群的焦虑程度。方法　对80名女性性传播疾病高危人群个体进行焦虑自评量表调查,计算其总分均值、总分上限和各题单项分均数,与常模进行比较。结果　女性性传播疾病高危人群组总分上限及焦虑、惊恐、乏力、胃痛或消化不良、尿意频数、面部潮红单项分均数均高于常模,差异有显著性(P <0 .0 5 ,P <0 .0 1) ;而发疯感、手足刺痛单项分均数低于常模,差异有显著性(P <0 .0 1)。结论　性传播疾病高危人群总的焦虑程度和某些焦虑因子水平高于正常人群。     

老年冠心病患者抑郁情绪及抑郁自评量表的诊断价值

目的调查老年冠心病患者的抑郁情绪,评价ZUNG抑郁自评量表在抑郁症诊断中的价值。方法连续纳入在我院住院的老年冠心病患者,应用中国精神疾病分类与诊断标准第三版(CCMD-3)制定的抑郁发作的诊断标准,调查抑郁症的发病比例;应用Zung抑郁自评量表(SDS)调查其抑郁症状的比例;受试者工作特征曲线(ROC)评价ZUNG对抑郁的诊断价值。结果 214例老年冠心病患者中抑郁症患者54例,占25.23%;有抑郁症状者为123例,占57.47%。受试者工作特征曲线(ROC)示曲线下面积为0.950〔(0.912,0.989),P=0.019〕,抑郁得分以45.5为分界值时,诊断抑郁症的敏感度为90.7%,特异度为83.1%。结论老年冠心病患者抑郁情绪严重;ZUNG对抑郁有较高的诊断价值。     

194例行胃镜检查老年患者焦虑和抑郁问卷分析

目的 评估接受电子胃镜检查的老年患者的焦虑、抑郁情况.方法 从2010年4月至6月我们采用SAS(焦虑)和SDS(抑郁)自评量表对在本院接受过电子胃镜检查的患者进行自评调查.结果 194例60岁以上接受电子胃镜检查的患者中,女性患者中焦虑、抑郁患者所占比例明显高于男性患者(P＜0.05)；有焦虑及抑郁的患者其在做胃镜检...     

系统护理对冠心病患者焦虑和抑郁情绪的影响

目的 探讨系统护理干预对冠心病(CHD)患者焦虑和抑郁情绪的影响.方法 选择确诊的冠心患者160例,将其分为对照组和系统护理干预组,每组各80例,通过焦虑自评量表(SAS)和抑郁自评量表(SDS)对各组患者进行焦虑和抑郁评分.结果 两组患者焦虑和抑郁评分均高于临界值(50分和41分).对照组护理前后焦虑和抑郁评分差异无统计学意义(P>0.05):系统护理干预组护理前后差异有统计学意义(P<0.05或P<0.01).护理干预后,系统护理干预组患者焦虑和抑郁评分明显低于对照组(P<0.05或P<0.01).结论 系统护理干预对CHD患者心理状况有明显的改善作用,对患者的早日康复起到积极作用.     

Zung自评量表焦虑、抑郁评分、炎性因子及冠状动脉病变相关性

目前普遍认为冠心病(CHD)是心身性疾病,炎性因子在冠状动脉粥样硬化的发生、发展中起重要作用.本研究通过对Zung自评量表焦虑、抑郁评分、炎症因子水平及冠状动脉病变范围的相关性研究,为CHD临床防治提供有益的尝试. 1资料与方法 1.1 研究对象2009年1～12月在东南大学附属中大医院心内科及华东疗养院老年科住院的CHD患者270例,男153例,女117例;年龄55 ～86[平均(69±6.6)]岁.     

焦虑和抑郁量表在肝硬化患者临床应用中的信效度评价*

目的 应用焦虑自评量表（SAS）和抑郁自评量表（SDS）调查肝硬化患者心理障碍状况,评价其在肝硬化患者中应用的信效度。方法 应用SAS和SDS量表对138例肝硬化患者进行问卷调查, 采用Cronbach’s α系数、分半系数、组内相关系数（ICC）反映量表的同质信度。采用探索性因子分析量表的结构效度,计算Kaiser-Meyer-Olkin（KMO）值,并作巴特利特球形检验（BTS）判断因子分析是否合适,采用主成分分析法提取因子。结果 本组肝硬化患者焦虑和抑郁患病率分别为38.2%和63.1%;SAS量表的Cronbach’s α系数为0.777,SDS量表的Cronbach’s α系数为0.782,两个量表具有良好的同质性信度;分别对SAS量表提取4个主要因子,其方差解释比例分别为15.4%、14.9%、10.6%和10.2%,4个因子累计解释总方差的51.1%;对于SDS量表提取5个主要因子,其方差解释比例分别为14.0%、12.6%、11.9%、10.3%和8.4%,5个因子累计解释总方差的57.4%;SAS和SDS量表重测分析发现,两次测量结果高度相关（P<0.001）。结论 应用SAS和SDS量表调查肝硬化患者焦虑和抑郁情况具有良好的信效度,可以用于肝硬化患者心理障碍的测定。     

综合医院心血管疾病合并焦虑抑郁的调查

目的了解心血管疾病患者并发焦虑抑郁的状况。方法对120例心血管疾病患者和100例健康体检者采用焦虑自评量表(SAS)和抑郁自评量表(SDS)进行问卷调查,分别评分进行比较分析。结果心血管病患者的SAS、SDS评分均明显高于对照组;120例心血管疾病患者中合并焦虑抑郁71例,占59.7%,其中焦虑状态35例(29.17%),抑郁状态22例(18.33%),焦虑抑郁状态14例(11.67%)。结论心血管疾病患者中有较高的焦虑抑郁发病率。     

Hospital anxiety and depression scale exhibits good consistency but shorter assessment time than Zung self-rating anxiety/depression scale for evaluating anxiety/depression in non-small cell lung cancer

This study aimed to compare Zung self-rating anxiety/depression scale (SAS/SDS) and hospital anxiety and depression scale (HADS) regarding the detection rate, detection consistency, and time of assessment in non-small cell lung cancer (NSCLC) patients.Totally 290 NSCLC patients who underwent surgical resection were consecutively recruited and clinical data of patients were collected. Patients’ anxiety and depression were assessed using HADS and SAS/SDS when they were discharged from hospital and consumption of the time for completing HADS and SAS/SDS was recorded.The anxiety detection rates by SAS (57.9%) and HADS-A (51.0%) were of no difference (P = .095). Also, there was no difference in anxiety severity detected by the 2 scales (P = .467). Additional correlation analysis revealed that both anxiety scores (r = 0.702, P < .001) and detected anxiety (Kappa = 0.626, P < .001) were consistent by SAS and HADS-A. Regarding depression, depression detection rate by SDS (47.6%) was higher than that of HADS-D (39.3%) (P = .044); the depression severity by SDS was more advanced than that by HADS-D (P = .002). The subsequent correlation analysis showed that both depression scores (r = 0.639, P < .001) and detected depression (Kappa = 0.624, P < .001) were consistent by SDS and HADS-D. In addition, the time for HADS assessment (7.6 ± 1.2 minutes) was shorter than SAS/SDS assessment (16.2 ± 2.1 minutes) (P < .001).HADS could be a better choice for assessing anxiety and depression in NSCLC patients, benefiting from its shorter assessment time but consistent detection rate compared with SAS/SDS.     

功能性胃肠病患者自评量表心理测评150例分析

目的 探讨功能性胃肠病(FGIDs)患者焦虑、抑郁性情绪障碍的心理过程及心理活动水平.方法 采用抑郁自评量表(SDS)和汉密顿焦虑量表(HAMA),对2007年4～11月南方医科大学南方医院消化科门诊收治的150例FGIDs患者,包括肠易激综合征(IBS)50例,功能性消化不良(FD)50例和胃食管反流病(GERD)50例及35名同期健康体检者进行心理测评.结果 150例FGIDs患者SDS评分≥50分者100例(66.7%),HAMA评分≥14分者59例(39.3%),与对照组比较差异有统计学意义(P<0.05),但3种疾病间差异无统计学意义(P>0.05).结论 FGIDs患者存在着明显的抑郁和焦虑精神心理障碍,因此,时FGIDs的诊治过程中临床医生应高度重视精神心理因素.     

老年男性体检人群焦虑和抑郁调查分析

目的探讨老年男性体检人群焦虑和抑郁的患病水平及主要影响因素,为早期开展针对性防控提供依据。方法采用医院焦虑抑郁量表(HADS),对解放军总医院2015年3月至2015年7月1132例接受常规健康体检的老年男性进行横断面调查,年龄(75.2±9.5)岁,其中60~69岁364例,70~79岁363例,≥80岁405例。结果老年男性体检人群焦虑和抑郁问题相对较轻,焦虑阳性率为2.5%,抑郁阳性率为4.3%。其中≥80岁高龄老年人的焦虑和抑郁阳性率分别为2.5%和6.4%。饮食偏好和睡眠障碍是影响老年男性人群焦虑和抑郁的危险因素。饮食偏好对焦虑和抑郁阳性率影响的OR值分别为2.10(95%CI:1.03~4.26,P=0.041)和1.84(95%CI:1.07~3.18,P=0.028)。睡眠障碍对焦虑和抑郁情绪阳性率影响的OR值分别为1.81(95%CI:1.10~2.97,P=0.002)和2.77(95%CI:1.47~5.23,P=0.020)。饮酒是老年男性人群抑郁的保护因素,其OR值为0.47(95%CI:0.27~0.84,P=0.010),即相对于现在不饮酒者(包括既往饮酒和从不饮酒),现在饮酒者发生抑郁的风险下降53%。结论老年男性体检人群焦虑和抑郁问题相对较轻。饮食偏好、现在饮酒和睡眠障碍是影响因素。这也提示我们要重视老年人群的焦虑和抑郁问题,并早期开展针对性干预措施,以减少严重心理问题的发生。     

心内科门诊患者躯体症状与焦虑、抑郁的相关分析

目的对在广州地区综合医院心内科门诊就诊的患者进行焦虑、抑郁症状和躯体症状的现状调查,并探讨躯体症状与焦虑、抑郁的相互关系。方法通过随机抽样从广州市卫生局抽取广州6家大型综合医院,采用医院焦虑抑郁量表(hospital anxiety and depression scale,HADS)和患者健康问卷(patient health questionnaire-15,PHQ-15)对906例在综合医院心内科门诊就诊的患者进行量表评定,统计患者焦虑、抑郁检出率及不同程度躯体症状患者焦虑、抑郁患病相对危险度。结果906例门诊患者中,焦虑、抑郁及焦虑、抑郁合并现患病率分别为12.6%、9.7%、16.6%。躯体症状与焦虑、抑郁的相关分析显示,PHQ-15总分、PHQ-15阳性症状数目与HADS总分(r=0.512,P<0.01;r=0.475,P<0.01)、HAD-A因子分(r=0.504,P<0.01;r=0.469,P<0.01)及HAD-D因子分(r=0.431,P<0.01;r=0.399,P<0.01)呈正相关。躯体症状轻度(PHQ-15,5～9分)、中度(PHQ-15,10～14分)、重度(PHQ-15,15～30分)患者焦虑患病的相对危险度(relative risk,RR)及95%可信区间(confidence interval,CI)分别为4.41(1.98～9.86)、13.95(6.38～30.51)、47.73(18.74～121.53);抑郁患病的相对危险度[RR(95%CI)]分别为2.14(0.95～4.83)、6.96(3.12～15.51)、15.70(6.26～39.36);焦虑、抑郁合并患病的相对危险度[RR(95%CI)]分别为3.56(1.59～7.95)、10.70(4.91～23.32)、32.66(13.68～78.02)。结论综合医院心内科门诊就诊患者焦虑、抑郁常见;躯体症状与焦虑、抑郁密切相关,躯体症状程度越重,躯体症状数目越多,患焦虑、抑郁相对危险度越高。     

Improvement in social anxiety following a return-to-work intervention for patients with depression

Purpose:To retrospectively examine depression and social anxiety improvement in patients on sick leave due to depression who participated in a return-to-work intervention (RTW-I) program.Methods:Patients visited a psychiatric outpatient clinic simulating workplaces to learn recurrence prevention skills through RTW-Is, including group cognitive behavioral therapy, from April 1, 2013, to September 30, 2017. The Beck Depression Inventory-Second Edition (BDI-II), Social Adaptation Self-Evaluation Scale (SASS), and Liebowitz Social Anxiety Scale (LSAS) scores of 112 patients were analyzed before and after the intervention program. Missing postprogram data were substituted using the last observation carried forward scores. Next, 45 patients who responded to the work continuity survey 1 year after RTW-I were categorized into Group A (patients who continued working: 37) and Group B (those who did not continue: 8).Results:The mean BDI-II scores significantly decreased from preintervention 19.4 to postintervention 7.9 (t = 13.303, P < .001). The mean SASS scores significantly increased from preintervention 31.9 to postintervention 36.0 (t = −5.953, P < .001). The mean LSAS scores significantly decreased from preintervention 54.7 to postintervention 37.0 (t = 8.682, P < .001), and all scores demonstrated an improvement. Patients who continued working showed improved depressive and social anxiety symptoms. The BDI-II and SASS scores showed no significant differences between the groups, but the postintervention LSAS scores were significantly different (P = .041). LSAS score changes: Group A = −26.2; Group B = −9.8; estimated difference: −17.920, 95% CI: −32.181 to −3.659, P = .015.Conclusions:The RTW-I program improved depressive and social anxiety symptoms. Patients with improved scores continued working for 1 year after the intervention.Trial registration: This trial was retrospectively registered with the UMIN Clinical Trial Registry (UMIN-CTR) (ID: UMIN000037662) on August 10, 2019.     

Pain-related anxiety in relation to anxiety and depression among persons living with HIV/AIDS

Persons living with HIV/AIDS (PLHA) experience clinically significant pain as a result of HIV and such pain is often related to increased levels of anxiety/depression. Pain-related anxiety has been identified as a mechanism in the onset and progression of pain experience and associated affective distress. However, there has not been empirical study of pain-related anxiety in relation to affective processes among PLHA. To address this gap, hierarchical multiple regressions were conducted using SPSS v.21 to examine pain-related anxiety (as measured using the Pain Anxiety Symptoms Scale) in relation to anxiety and depressive symptoms (as measured using the Mood and Anxiety Symptoms Questionnaire) among 93 PLHA (10.8% female; Mean age?=?49.63, SD?=?8.89). Pain-related anxiety was significantly related to anxious arousal symptoms (β?=?.43) and anhedonic depressive symptoms (β?=?.25); effects were evident beyond the variance accounted for by CD4 count, race, sex, income level, and current level of bodily pain. The present results suggest that pain-related anxiety may play a role in the experience of anxiety and depressive symptoms among PLHA.     

便秘型肠易激综合征患者直肠肛管压力的改变与焦虑/抑郁情绪测定评分的临床意义

[目的]探讨便秘型肠易激综合征(IBS-C)患者直肠肛管压力的变化及其与焦虑/抑郁情绪测定评分的关系与意义。[方法]选择确诊为IBS-C的患者70例为试验组、健康志愿者24例作为对照组,采用肛管直肠测定仪进行动力学检查,并采用综合医院焦虑/抑郁情绪测定表进行心理状况评估,比较2组直肠肛管的压力和情绪测定评分的差异。[结果]试验组患者直肠初始感觉阈值、初始排便感觉阈值、直肠最大容量感觉阈值均高于对照组(P0.05);试验组直肠肛门抑制反射阈值和肛管静息压高于对照组,但2组比较差异无统计学意义(P0.05);试验组肛管最大自主收缩压低于对照组、焦虑评分与抑郁评分显著高于对照组(均P0.05)。[结论]IBS-C患者存在明显的直肠感觉功能的障碍和盆底肌协调运动障碍,且存在焦虑抑郁症状,为临床诊治提供了依据。