整合药学专业化学实验课程探索建立教学新模式

针对目前各高校药学专业无机化学、有机化学、分析化学、物理化学各自独立开设,不利于培养学生综合利用化学知识,解决药学实际问题的现状,提出整合四大化学内容,按基本操作——验证实验——综合性实验——设计性实验四个阶段循序渐进,既培养了学生扎实的操作技能,又提高了学生综合实践能力和创新精神。为药学专业化学实验教学提出了新模式,开辟了新途径。     

药学专业无机化学实验教学改革的一点探索

为了适应高等医药专业教育的发展形势和当前社会对于创新型人才的迫切需要,近几年来,我们在药学专业无机化学实验教学中不断摸索,选择部分实验教学班建立无机化学实验教学改革试点,以能力培养为核心进行改革探索与实践研究,努力探索适合当前时代要求的无机化学实验教学模式和师资队伍培养模式,改革重心是增加设计性的实验项目,丰富实验教学内容;引入讨论式教学方法,构建新型实验教学体系;增加科研思维的培养,优化实验教学过程;更新实验教学手段,改革实验考核模式,目的在于培养出具有创新能力的新世纪人才,培养出综合素质较高的药学专业的学生,这对于有效提高本科教育质量、增强高校毕业生的核心竞争力具有重要的意义。     

浅谈无机化学绪论课的教学

无机化学是中药学及药学专业的第一门化学基础课,绪论课的教学非常重要。本文从学习化学的目的、化学与药学的关系以及学习无机化学的方法等方面对无机化学绪论课的教学进行了探讨。     

应用小量-半微量实验技术改进化学实验课的实践

把小量—半微量实验技术引入药学专业化学实验课，使化学实验教学逐渐向清洁工艺、绿色化学方向转化。通过阐述小量—半微量实验技术在药学专业化学实验课中应用的意义及前景，探讨阿司匹林和磺胺醋酰两药物小量—半微量的合成方法，证实小量—半微量实验技术对化学实验教学的优越性、可行性和必要性。     

将微格教学法应用于无机化学实验教学

为提高实验教学效果,在无机化学实验中引入微格教学。统计结果显示,实验组学生在实验操作能力和分析问题能力上明显优于对照组,实验理论的掌握两者没有显著差异。从结果来看,微格教学法适合在化学实验教学中推广应用。     

微格教学法在药学专业无机化学实验中的应用

为提高实验教学效果,在无机化学实验中引入微格教学.统计结果显示,实验组学生在实验操作能力和分析问题能力上明显优于对照组,实验理论的掌握两者没有显著差异.从结果来看,微格教学法适合在化学实验教学中推广应用.     

高职高专药学类专业基础化学实验教学的改革

阐述了我院药学类专业基础化学实验教学存在的一些问题。因此,加强对基础化学实验教学的改革势在必行,要在课程体系、实验教学内容、实验方式、实验考核模式等方面加大改革的力度,不断改善实验室环境条件,不断端正学生实验态度达到提高教学质量,确保＂高素质技能型＂人才培养目标的实现。     

改革药学专业无机化学教学的探讨

为适应新世纪药学教育由传统的“化学”模式向“化学—生物学—医学”模式的转变,对药学专业无机化学的教学理念、教学内容和教学方法的改革进行了探讨。     

浅谈药学专业无机化学课程考核方法改革

无机化学课程是药学类专业本科生的第一门专业基础必修课,相比其他专业而言,药学类专业对学生的化学知识要求更高。它承接中学化学与大学化学课程以及药学专业课程,对药学专业学生的分析化学、有机分析、物理化学以及药物化学、药物分析、药理学、药物动力学等专业课程的学习都起到重要作用。     

在天然药物化学实验课教学中开展研究型实验的实践

阐述在药学本科生中开展天然药物化学研究性实验的实践和体会。研究型实验教学伴随着社会对综合型人才需求以及教学改革的不断深入应运而生,它以不同的形式应用于实验教学改革中,改变传统的实验教学模式,提高学生学习的积极性、主动性、创新性、团队精神、诚信态度,亦可以提高教师的素质。     

"思路教学法"在药理学实验教学中的应用

应用"思路教学法",初步探讨了带教药理学实验的一个基本模式。该教学法得到了学生的认可。它的应用,优化了实验内容的课堂教学,并有利于提高学生学习的积极主动性,能够培养学生的"思路",强化素质教育。     

安全药理学研究的基本要求及其规范化

安全药理学是从药理学、生理学和毒理学发展而来的一门独立的综合性药理学学科。安全药理学研究之目的是识别、监控并确定非临床研究中出现潜在的不期望的药效活性。本文分析安全药理学的现状,讨论实验设计的基本要求,对中枢神经系统、心血管系统和呼吸系统实验设计的规范化提出了建议。     

在有限条件下进行药理学实验教学改革

在有限的办学条件下,充分利用现有资源,训练学生药理学实验基本技能,强化学生对药理实验中“量”的理解,注意提高学生学习兴趣,培养学生独立思考的能力和实事求是的科学精神,增设命题式设计性实验,加强生命伦理教育,使用现代教学手段,努力提升学生综合素质,使学生初步建立较完善的药理学实验学科体系,达到高职高专人才培养的要求。     

P15 Teaching of pharmacology for using medicine in reason

Teaching of pharmacology is very important to clinic practice, and it is stability basic of theory for using medicine in reason. To study knowledge frame of pharmacology teachers,the teaching method in existence and experiment in teaching of pharmacology, find out a good many things about theory renegades from practice, then to explore reformation. The teachers who engaged teaching about pharmacology did not joint in the clinic work. They lack know ledge of clinic, and bring on separate theory from clinic practice. It is no uses to cultivate students rising medicine in reason. So the teachers pay attention to advance theory, to advance ability of scientific research, at the same time, must be concerned with the clinic jobs. Next, the teachers insist to accumulate knowledge in teaching of tradition. The students did not know about system info in pharmacology, they did not content clinic practice, then to bring out weary emotion. So we can trade a think in the teaching might as well that we handpick representational part from typical clinic example, and to lead to students thinking problem, then settle problem. This course need to understand correlation knowledge, must be found their relation each other. It is important to blaze student learning. The third, the part of experiment in the pharmacology are less, so we must increase content of experiment, and let the students design all experiment approach, and to actualize it. The teachers give some guidance to students. The result of experiment will be related with discourse. The teachers appraise it according to its quality. It will be reckoned in the achievement of term end. We must give some busywork that let the students researching one or tow medicine in reason is a keystone in the clinic practice. To realize it, teaching pharmacology will be joined with clinic practice compactness.     

天然产物降血糖成分的研究进展

本文介绍了2000年以来国外天然降血糖药物的化学、药理等方面的研究情况,这些天然产物的水提取物或醇提取物或烷提取物具有降低实验动物血糖效果。对已明确降糖成分的天然产物,根据不同化学结构,分皂甙、萜、多糖、黄酮、生物碱及硫键化合物等六大类进行阐述。     

Tropane alkaloids in pharmaceutical and phytochemical analysis

Alkaloids with tropane skeleton, present in many species of Solanaceae family, constitute important raw materials for variety of pharmaceutical preparations. Although basic facts concerning chemistry and pharmacology of these compounds date back to XIX century, the wealth of data accumulated recently has challenged many established opinions, particularly in the field of biogenesis. Advances in analytical techniques which made this progress possible are discussed, in reference to contemporary requirements for specification of active pharmaceutical ingredients.     

鱼腥藻毒素(Anatoxins)研究进展

综述鱼腥藻毒素的药理与化学方面的研究进展。     

Tropane alkaloids in pharmaceutical and phytochemical analysis

Alkaloids with tropane skeleton, present in many species of Solanaceae family, constitute important raw materials for variety of pharmaceutical preparations. Although basic facts concerning chemistry and pharmacology of these compounds date back to XIX century, the wealth of data, accumulated recently, has challenged many established opinions, particularly in the field of biogenesis. Advances in analytical techniques which made this progress possible are discussed, in reference to contemporary requirements for specification of active pharmaceutical ingredients.     

Personalized medicine: the impact on chemistry

An effective strategy for personalized medicine requires a major conceptual change in the development and application of therapeutics. In this article, we argue that further advances in this field should be made with reference to another conceptual shift, that of network pharmacology. We examine the intersection of personalized medicine and network pharmacology to identify strategies for the development of personalized therapies that are fully informed by network pharmacology concepts. This provides a framework for discussion of the impact personalized medicine will have on chemistry in terms of drug discovery, formulation and delivery, the adaptations and changes in ideology required and the contribution chemistry is already making. New ways of conceptualizing chemistry's relationship with medicine will lead to new approaches to drug discovery and hold promise of delivering safer and more effective therapies.