Mixed aneurysmal and obstructive coronary artery disease causing acute myocardial infarction in a young woman with Takayasu's arteritis

Takayasu's disease is a chronic inflammatory pathology of the aorta and its main branches. The present report describes a rare presentation of the disease in a young woman who presented with anterior myocardial infarction, and was subsequently found to have mixed aneurysmal and obstructive coronary artery disease involving the left anterior descending artery and its diagonal branches. Issues surrounding the management of coronary artery disease in this patient are discussed.     

血栓抽吸治疗冠状动脉瘤内血栓形成导致心肌梗死1例

冠状动脉瘤样扩张又称冠状动脉瘤(CAA)。CAA内血栓形成导致急性心肌梗死在临床上比较少见,患者病变瘤体内往往血栓负荷较重。强化抗血小板聚集、支架置入等常规治疗策略可能并不适合这类患者。本文报道1例采用单纯血栓抽吸、术后长期抗凝联合冠心病二级预防治疗CAA内血栓形成导致心肌梗死患者。     

Cannabis-induced coronary artery thrombosis and acute anterior myocardial infarction in a young man

Information concerning acute myocardial infarction after cannabis usage is limited and the actual mechanism of cannabis-induced myocardial infarction is not well known. In the report, we described a young man with an acute myocardial infarction and cannabis-induced coronary thrombosis.     

Acute myocardial infarction associated with coronary spasm in a young man

CASE REPORT Acute myocardial infarction(AMI) is usually caused by atherosclerotic plaque disruption and thrombus formation.However,AMI is occasionally caused by coronary spasm too.We are reporting a case with AMI due to coronary spasm whose serial electrocardiogram(ECG) showed dynamic changes of T waves in precordial leads.     

Giant cell arteritis of coronary arteries causing myocardial infarction.

A case of giant cell arteritis involving the coronary arteries and causing thrombosis and myocardial infarction is described. IgM deposits in the affected arteries were demonstrated by an immunoperoxidase technique.     

Spontaneous coronary artery dissection in a young man with anterior myocardial infarction

A case of spontaneous coronary artery dissection in a young male with subsequent myocardial infarction is reported. In addition, distal vessel occlusion is noted, presumably from embolization of thrombotic material originating from the site of dissection. Postulated mechanisms of this uncommon cause of myocardial infarction and subsequent therapeutic options are reviewed.     

Aspergillus coronary embolization causing acute myocardial infarction

An increased frequency of disseminated aspergillosis has been observed in the last decade, mostly occurring in immunocompromised patients including the bone marrow transplant population. Cardiac involvement by Aspergillus remains rare. We report the clinical and postmortem findings of an unusual case of Aspergillus pancarditis in a 7-year-old bone marrow transplant patient with Aspergillus embolization to the coronary arteries leading to a massive acute myocardial infarction. This case suggests that myocardial injury secondary to disseminated aspergillosis should be included in the differential diagnosis of chest pain in the immunocompromised pediatric patient.     

Spontaneous coronary artery dissection in a young man with anterior myocardial infarction.

A case of spontaneous coronary artery dissection in a young male with subsequent myocardial infarction is reported. In addition, distal vessel occlusion is noted, presumably from embolization of thrombotic material originating from the site of dissection. Postulated mechanisms of this uncommon cause of myocardial infarction and subsequent therapeutic options are reviewed.     

Pure ventricular septal myocardial infarction in a young man with coronary artery ectasia

The case of a 30-year-old man with myocardial infarction localized in the interventricular septum is described. Coronary angiography performed on day 28 after the onset of symptoms revealed ectasia in the right and left coronary arteries, but no overt stenotic or occlusive lesions were present. Spasm was induced in the first septal branch of the left anterior descending artery by an acetylcholine provocation test, and single photon emission computed tomography myocardial perfusion imaging showed a reduced thallium-201 uptake localized in the interventricular septum.     

Spontaneous coronary arterial dissection causing acute myocardial infarction

We report the case of a middle-aged female who presented with an acute inferior myocardial infarction treated with intravenous thrombolytics. Immediate coronary angiography demonstrated the presence of a spiral dissection and a large thrombus. After 1 week of anticoagulation the thrombus had resolved, but a large spiral dissection persisted. This was confirmed by intracoronary ultrasound. We then review the literature on spontaneous coronary arterial dissection.     

Myocardial infarction in a young woman with isolated coronary arteritis

A 26-year-old black woman presented with a febrile illness and subsequently sustained an inferior myocardial infarction with chest pain. CPK-MB elevation and ECG changes. Left ventriculography revealed inferior wall hypokinesis, and coronary angiography demonstrated multiple aneurysms of the coronary arteries. Findings on visceral angiography of multiple organs was normal. Various etiologies were considered; however, her clinical course was felt to be most consistent with periarteritis nodosa and steroid therapy was instituted.     

Coronary artery aneurysms in a young patient with acute myocardial infarction: a case report

Coronary artery aneurysms are not uncommon. They are usually arteriosclerotic in origin, and may be congenital or secondary to injury, dissection, infection, inflammation, or Kawasaki disease (KD). Herein, we report a case involving a 25-year-old male smoker with acute myocardial infarction (AMI). Coronary angiography showed triple-vessel disease, coronary artery aneurysms, and diffuse ectasia. Coronary artery bypass grafting was performed without complications. Based on his history, serologic examinations, and angiographic findings, we suspected that his coronary artery aneurysms and ectasia were the adult sequelae of KD. This case is a good reminder that KD victims may suffer from young-onset AMI.     

反复急性冠状动脉栓塞致心肌梗死一例

<正>1病例资料患者女性,57岁。因"突发胸痛2 h"于2008年8月16日入院。患者胸痛发作时正在步行上坡,胸痛部位位于前胸偏右侧,呈持续性胀痛,伴气短、心悸。既往史:30年前开始无诱因出现阵发性心悸、气短,左前胸点状疼痛,含服硝酸异     

年轻人急性心肌梗死的常见诱因分析

目的:探讨年轻人急性心肌梗死(AMI)的常见诱因.方法:将≤35岁的AMI患者20例作为青年组,以年龄＞35岁的AMI为对照组,对2组的不良生活习惯及诱因进行分析.结果:青年组吸烟20例,凌晨发病20例,运动少20例,睡眠少20例,无一例冠状动脉狭窄≥50%;对照组凌晨发病15例,血脂异常17例,肥胖19例,冠状动脉狭窄≥50% 20例;对上述结果进行统计学分析显示,2组均差异有统计学意义(P＜0.05～0.01).结论:吸烟、凌晨发病、运动少、睡眠少是年轻人AMI的主要危险因素;而血脂异常和肥胖等基础疾病是＞35岁AMI的危险因素.     

Hypertensive crisis in young woman with Takayasu arteritis

A young woman who was experiencing repeated convulsions was admitted. The patient's brain magnetic resonance image revealed reversible posterior leukoencephalopathy. Blood pressure fluctuated at times to more than 200 mmHg, and the measurement of the right and left upper arms differed by approximately 70 mmHg. Enhanced computed tomography revealed stenotic lesions of some arteries including the left renal artery. Such findings led to an initial diagnosis of Takayasu arteritis and hypertensive encephalopathy caused by renovascular hypertension. A percutaneous transluminal renal angioplasty was successfully performed. The patient's blood pressure returned to normal value without the use of antihypertensive drugs.     

Acute myocardial infarction with simultaneous occlusions of two major coronary arteries in a young man

Simultaneous formation of the thrombi in two different coronary arteries is a very rare event. We present a 34-year-old man with acute myocardial infarction due to simultaneous occlusion of the two major coronary arteries. His only risk factor was smoking 40 cigarettes daily. Emergency arteriography revealed a total occlusion of the proximal left anterior descending artery (LAD) and the left circumflex coronary artery (LCx). We performed primary angioplasty to the LAD and instituted thrombolytic therapy to the LCx. During intra-aortic balloon pumping and medical treatment, the patient had no symptoms of angina. He underwent a second catheterization 4 weeks after primary angioplasty. After intravenous ergonovine provocation, coronary arteriography revealed diffuse vasospasm of the LAD and the LCx. These data suggest that habitual heavy smoking and coronary spasm may have been causatory factors for myocardial infarction in this case.     

Simultaneous multivessel coronary spasm causing acute myocardial infarction: a case report

Spontaneous simultaneous multivessel coronary artery spasm in patients with acute myocardial infarction (AMI) is uncommon. A 79-year-old Japanese man was transferred to this hospital because of severe prolonged chest pain and faintness. Left coronary angiography revealed total occlusion of the left anterior descending and the left circumflex coronary arteries. Moreover, right coronary angiography revealed 99% stenosis of the right coronary artery. After intracoronary administration of nicorandil, left coronary artery and right coronary artery angiography revealed no organic stenosis or thrombus. This is the first report in which simultaneous 3-vessel spasm was documented by emergency angiography in AMI.     

Takayasu arteritis in children and young indians

Twenty four patients of Takayasu arteritis (TA) aged less than 18 years were studied over a period of 20 years (1978-98). There were 4 males and 20 females with a male:female ratio of 1:5. The mean age of presentation was 14 years and the disease had a mean onset of time 4+/-1.5 months prior to admission to the hospital. Hypertension was the commonest mode of presentation seen in 83% of patients. 16% patients had congestive heart failure. Left ventricular hypertrophy was present in 54% patients. Angiographic findings showed that abdominal aorta was the commonest segment of aorta that was involved (71% cases). Renal artery was involved in 75% cases. Treatment modalities included antihypertensive drugs in 19 patients, antitubercular drugs in 7 patients and steroids in 7 patients. Renal angioplasty was performed in 2 patients with excellent results. On follow up 2 patients died. The causes of mortality were renal failure and heart failure in one patient each. The clinical profile of young patients with TA is similar to that of adults with this disease.