A microcomputer-based system for multi-channel neurophysiological recording

A set of software utility programs is described which, in association with a microcomputer and a commercially available analog-to-digital converter may be used to acquire, store, manipulate and display large amounts of behavioral and/or physiological data in digitized form.     

A microcomputer-based vision system for area measurement

A vision system for measuring the area of an arbitrarily shaped object is described. The algorithm consists of a gray-level thresholding technique combined with a region correction procedure based on mathematical morphology. All processing steps are carried out on a microcomputer system equipped with a video digitizer. The algorithm has been successfully applied to a number of images of medical interest including skin wounds and various microscopic-scale objects such as cell cross-sections and multicellular tissues. Excellent agreement between results obtained by the automatic method and by using standard mechanical means has been established experimentally. The approach is demonstrated by a number of experimental examples.     

A microcomputer-based system for detailed analysis of rat behavior

A microcomputer-based system that can measure rotational behavior and moving velocity is described. Infrared photobeams detect the animal behavior. One advantage of this system is that data can be stored on floppy disks and analyzed in arbitrary time intervals. This system may be useful for detailed analysis of rat behavior in physiological or psychopharmacological experiments.     

A microcomputer-based preventive maintenance system.

A medical equipment preventive maintenance system using a Radio Shack microcomputer is described. The system generates a schedule of equipment to be inspected each week. The software is written in BASIC for easy modification or transfer to other commercially available microcomputers. The system has been in use for nine months with good results.     

A microcomputer-based system for stereotaxic coordinates in the rat brain

In this report, the computer hardware and software used in the generation of a stereotaxic rat brain atlas are described. The atlas consists of sagittal and frontal sections drawn to the high-resolution page of the Apple II series computer. Brain architectural and macroscopic areas are represented by lines. Microscopic areas are represented by dots. The system employs a large data base to make available hundreds of brain areas on stereotaxic sections containing precise positional information of thousands of specific locations. For each display, the brain area is identified by name and by cross-hairs with digital display of stereotaxic coordinates. These coordinates may be referenced by earbar-zero or bregma. Other program options allow the printing of brain sections and a listing of available brain areas. Although designed for research in the neurosciences, the software may also be used for educational purposes.     

A microcomputer-based device to simulate biomechanical environments for cultured cells.

We describe software and hardware for a microcomputer-based cyclic strain device which applies programmed cycles of elongation and relaxation to cultured cells. This system has the potential to simulate many of the complex mechanically active environments found in living systems. As a sample application, we use it to simulate the cyclic stresses to which vascular smooth muscle cells in the arterial system are exposed.     

A microcomputer-based data acquisition system for a prosthetic heart valve test apparatus

The hydrodynamic testing of prosthetic heart valves in the laboratory under pulsatile flow conditions remains the only way of obtaining detailed information about valve function. Test procedures have become increasingly sophisticated, with a variety of different test conditions and detailed analysis of the pressure and flow signals. A computerized data acquisition system has been developed for use with the Glasgow pulsatile flow test apparatus. The computer collects seven signals from the test rig over a period of 20 s, and calculates the average waveform for each signal. Standard parameters, such as mean pressure differences, mean flows, regurgitant volumes and energy losses, are calculated automatically. The complexity of the analysis and the need for standardized documentation makes computerization essential. The system has been used extensively for function tests on over 160 prosthetic heart valves.     

A microcomputer-based, R-wave triggered system for hemodynamic measurements in the forearm

A microcomputer (with 8088 or 80286 processor)-based, R-wave triggered system for on-line, semi-continuous measurement of blood flow of one or two limbs, simultaneous with heart rate and eventually intra-arterial blood pressure, is described. The minimal interval between measurements is approximately 4 s, allowing the accurate measurement of maximal flow after ischemia. When compared to hand-operated plethysmography, the use of this system improves the precision of the measurements, minimizes perturbations of the limb circulation and eliminates the possible bias of analysis by hand.     

A microcomputer-based system to evaluate cardiac pacing for the treatment of tachycardias

A microcomputer-based pacemaker system for the evaluation of pacemaker treatment of tachycardia is described. The system may be used to study tachycardia initiation, tachycardia termination or a combination of the two. The software incorporates a visual display unit screen handling package which provides the user-system interface. System-patient interfacing is performed by a separate pacing and sensing unit which communicates with the computer via standard digital input/output lines. Several pacing options are available, selectable from a screen-displayed menu. Each selection also has an associated set of programmable parameters which may be adjusted, within allowed limits, to suit particular studies. Examples of the use of the system for tachycardia termination are given. The main programming language for the controlling software was Fortran IV. Some routines were necessarily written in assembly language. The system is useful for evaluation purposes and forms the basis of a cardiac pacemaker development tool.     

康复解剖学中开展研究性学习和训练的实践

<正>神经传导通路、脊柱区解剖、全身骨骼肌起止点作用等知识既是解剖学中难点~([1-3]),也是康复解剖学中的重点~([3])。为了促进康复专业学生更好地掌握这些知识,为专业课和临床实践打下扎实的基础,本院在康复专业学生中先后开展了3个方面的实践创新训练项目,取得了良好的效果。1指导学生申报省大学生创新训练项目根据康复专业学生的申请,本人分别在2012年、2013年、2014年担任了3个实践创新训练项目的导师,指导了与解剖密     

DataVoice: A microcomputer-based general purpose voice-controlled data-collection system

An integrated system of hardware and software has been developed to combine the input of coordinate data from a digitizing pad with voice input for object identification or classification. The menu and voice-controlled software generates a sequential ASCII file which contains an object identification section and a data section. Rules for data entry and analysis programs have been developed for several applications. These are being tested and include general stereological analyses, bone, kidney and skin histomorphometry, boundary analyses, neuron classification and malignancy grading.     

A microcomputer-based prosthetic limb controller: Design and implementation

This paper describes the design and implementation of a microcomputer based myoelectric limb controller. This controller was constructed for use as a feasibility study of, and a development tool for, microcomputer-based myoelectric limb controller applications. Features of this approach include flexibility and computational power. The present design uses low-power CMOS technology to provide a system in which most of the new computationally and decision orientated myoelectric signal processing algorithms can be used. Two CMOS microprocessors, a CD80C86 and a MC146805E2, are used, but microcomputer power consumption is only 120 mA.     

A microcomputer-based data acquisition system for continuous recording of feeding and drinking by rats

A monitoring system to continuously record the daily pattern of drinking and eating of rats is described. This system, based on a North Star microcomputer, can record the amount of food ingested with a temporal resolution of +/- 1.0 second and quantitative accuracy within +/- 5%. Drinking behavior is detected using a drinkometer which also has a temporal resolution of +/- 1.0 second. Data are analyzed by computer to determine absolute amounts of consumption and patterns of intake. The patterns of feeding and drinking recorded by this system are similar to those observed using other monitoring devices.     

A microcomputer-based graphical reconstruction technique for serial sectioned objects, with hidden line removal

The presented software package fulfills the need for processing serial sections with a microcomputer configuration, enabling three-dimensional reconstruction with hidden line removal. The language used is an interpreted BASIC-dialect (HPL). The input is performed via an interactive program. The object can be rotated in space. The Hidden Line algorithm does not depend upon a raster technique. Points of intersection of successive contours are calculated and inserted, thus providing drawings of high resolution and quality. The handling time can be said to be short, especially when considering the capacities of the microcomputer configuration used.     

A microcomputer-based method for physiologically interpretable measurement of the rewarding efficacy of brain stimulation

Determination of the function relating rate of pressing to the number of pulses in a train of fixed duration (the rate-frequency function) yields a physiologically interpretable measure of changes in the rewarding efficacy of the stimulation, because the number of action potentials in the reward-relevant first stage axons is directly proportional to the number of pulses in the train. We describe a system, based on a low cost microcomputer, which permits determination of 16-data-point rate-frequency functions in 4-6 animals simultaneously in less than 10 minutes. We give an empirical and theoretical justification for using the curve-shift measurement procedure in drug and lesion work, where the experimental treatments must be presumed to have substantial effects on performance factors.