Anaemia neonatorum

Ohne Zusammenfassung     

Sideroblastic Anaemia

Sideroblastic Anaemias are characterised by a) chronic hypochromic anaemia, b) ringed sideroblasts in the bone marrow, c) an increase in total body iron, d) ineffective erythropoiesis and e) often abnormal concentrations of F.E.P. A classification of Sideroblastic Anaemia is given and the pathophysiology of Sideroblastic Anaemia is discussed. A series of seven paediatric cases with Sideroblastic Anaemia is presented and the results of studies of the iron, vitamin B₆ and porphyrin metabolism are discussed. In two cases arguments for an ALA-synthetase deficiency are given. All five males were diagnosed as hereditary X-linked Sideroblastic Anaemia, one female as I.R.S.A. and the other female, who showed the features of the X-linked type, as congenital Sideroblastic Anaemia.     

Relapse of Hodgkin's Disease with Anaemia and Weight Loss

ABSTRACT. Two children previously treated for Hodgkin's disease had relapse associated with anaemia and weight loss but no other abnormal clinical findings. It was not possible to confirm the diagnosis by bone marrow aspirate or trephine and in each case laparotomy was required in order to establish a histological diagnosis.     

Über Anaemia neonatorum

Zusammenfassung Auf Grund der bisher in der Literatur niedergelegten Fälle und zweier eigener Beobachtungen wird versucht, die Symptomatologie, Ätiologie, Differentialdiagnose und Therapie der Anaemia neonatorum zu schildern.Bei dem einen Fall bestand ein aregeneratorisches Blutbild, d. h. keine Linksverschiebung, kein Auftreten von embryonalen Formen von roten und weißen Blutkörperchen, bei dem zweiten eine mäßige Regeneration, Normoblasten bis 9%, Reticulocyten bis 52:1000.Beide Fälle heilten nach 6 bzw. 22wöchentlicher Behandlung auf Bluttransfusion und Lebertherapie völlig aus.