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Noriyuki Nagai Nobuyoshi Takeshita Hitoshi Nagatsuka Masahisa Inoue Katsumi Nishijima Tetsudo Nojima Masako Yamasaki Chofuku Hoh 《Journal of oral pathology & medicine》1991,20(9):460-463
The histologic classification for odontogenic carcinomas is still under revision; thus, the differentiation between the terms "malignant ameloblastoma" and "ameloblastic carcinoma" has not been definitely stated. Nevertheless, it is recommended to reserve the former for those lesions that, in spite of an apparently innocuous histology, have given origin to metastatic growths, and to apply the latter for those ameloblastomas in which there is histologic evidence of malignancy in the primary, recurrent or metastatic lesions. A case of an ameloblastic carcinoma in the mandible is presented. Histologically, it was characterized by areas with features of a typical ameloblastoma and areas with anaplastic appearances. 相似文献
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Ameloblastic carcinoma is a rare malignant lesion with characteristic histologic features and behaviour that dictates a more aggressive surgical approach than that of a simple ameloblastoma. However, reliable evidence of its biologic activity is currently unavailable due to the scarcity of well-documented cases. It occurs primarily in the mandible in a wide range of age groups; no sex or race predilection has been noted. It may present as a cystic lesion with benign clinical features or as a large tissue mass with ulceration, significant bone resorption and tooth mobility. Because the lesion is usually found unexpectedly after an incisional biopsy or the removal of a cyst, a guide to differential diagnosis is not usually useful. The identifying features of ameloblastic carcinoma must be known and recognized by dental practitioners. Our understanding of the histologic features of ameloblastic carcinoma is somewhat vague. The tumour cells resemble the cells seen in ameloblastoma, but they show cytologic atypia. Moreover, they lack the characteristic arrangement seen in ameloblastoma. The clinical course of ameloblastic carcinoma is typically aggressive, with extensive local destruction. Direct extension of the tumour, lymph node involvement and metastasis to various sites (frequently the lung) have been reported. Wide local excision is the treatment of choice. Regional lymph node dissection should be considered and performed selectively. Radiotherapy and chemotherapy seem to be of limited value for the treatment of ameloblastic carcinomas. At the moment, there are too few reported cases to make a definite recommendation regarding treatment. Close periodic reassessment of the patient is mandatory. 相似文献
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P. Mainenti G.S. Oliveira J.B. Valério L.S.L. Daroda R.F. Daroda G. Brandão L.E.B. Rosa 《International journal of oral and maxillofacial surgery》2009,38(3):289-292
This paper reports one case, of an ameloblastic fibro-odontosarcoma (AFOS) affecting the mandible, in a 12-year-old girl. This neoplasm is a rare odontogenic neoplasm. To the authors’ knowledge this is the fifteenth case of AFOS reported in English. The patient's chief complaint was a swelling in the face for 6 months. An incisional biopsy was performed diagnosing the case as an ameloblastic fibroma. After radiography ameloblastic fibro-odontoma was diagnosed. Computed tomography was performed and a stereolithography model made to plan the surgical procedures. A hemimandibulectomy followed by a vascularized fibular flap was then proposed. The surgery was uneventful. Microscopic features diagnosed an AFOS. After 23 months of close follow-up there is no sign of recurrence or metastasis. Dental implants were recently placed in the fibular flap. 相似文献
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Ameloblastic fibro-odontoma is a benign epithelial odontogenic tumour with odontogenic mesenchyme exhibiting the histologic characteristics of ameloblastic fibroma and complex odontoma. It is usually associated with developing teeth and occurs predominantly in children and adolescents. In many cases, such lesions are found on radiographic evaluation of patients in whom eruption of teeth is delayed. Ameloblastic fibro-odontoma is generally asymptomatic but may cause swelling and discomfort. This report describes an ameloblastic fibro-odontoma in the posterior mandible of a 26-year-old woman and discusses the histogenesis and clinical features of the lesion. 相似文献
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The clinical case of an unusual ameloblastic fibro-odontoma (AFO) was reported. The patient's clinical chart as well as preoperative and postoperative radiographs and histological findings of a 20-year old man that addressed Dental Clinic at University of L'Aquila were thoroughly reviewed. The patient showed a swelling in the oral cavity and radiographic feature of a radiolucent lesion at left second premolar maxillary site. Histologic examination made diagnosis of AFO. AFO is a rare mixed odontogenic tumor with similarities to the ameloblastic fibroma (AF) and ameloblastic dentinoma. The nature and the relationships between mixed odontogenic tumours and related lesions are still controversial. Moreover is not clear if these lesions are separate pathologies or if they are different development stages of the same pathology. 相似文献
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Ameloblastic fibro-odontoma (AFO) is a rare mixed odontogenic tumor consisting of both ectodermal and mesenchymal components. It occurs predominantly in children and adolescents, especially in the mandibular posterior region. Histopathologically, AFO exhibits the combination of ameloblastic fibroma-like tissue and complex odontoma. A case of AFO in a 1-year-old child was presented. It produced an expansile lesion over the upper right anterior region and showed typical histopathological features of AFO. She was treated by enucleation with no recurrence observed after a follow-up period of 1 year. 相似文献
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Ameloblastic carcinoma of the maxilla. A case report 总被引:1,自引:0,他引:1
A case of an ameloblastic carcinoma in an unusual situation in the maxilla is presented. The lesion is characterized histologically by areas with features of a typical ameloblastoma and areas with anaplastic transformation. A Caldwell-Luc operation was followed by a recurrence after 3 years. Due to the advanced age and poor general health of the patient an enlarged, but not radical operation was performed. There is no evidence of metastatic tumour. 相似文献
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An unusual case of ameloblastic fibroma involving two supernumerary teeth in the anterior part of maxilla has been presented here. The radiographic picture mimics a dentigerous cyst where there is a gross migration of one of the involved super-numerary tooth. After the histopathological diagnosis, the lesion was treated with enucleation and curettage. 相似文献
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V M Phillips F W Grotepass R Hendricks 《The British journal of oral & maxillofacial surgery》1988,26(1):45-51
A case report of an ameloblastic odontosarcoma in which the epithelial component showed a dysplastic change is presented. The epithelium contained pleomorphic cells and numerous mitotic figures. 相似文献