A case report of intrapulmonary schwannoma

A 38-year-old man without any symptoms was admitted to our institution because of an abnormal shadow found incidentally on a chest X-ray. Chest computed tomography showed a round mass in the lingular segment of the left upper lobe. Lingular segmentectomy was performed, and the histopathological diagnosis was intrapulmonary schwannoma. Immunohistochemical staining revealed a positive result for S-100 protein and negative results for CD34 and desmin. We report this case of intrapulmonary schwannoma, which is extremely rare.     

原发性纵隔非典型脑膜瘤一例分析并文献回顾

［摘要］ 目的 探讨原发性纵隔非典型脑膜瘤的临床及影像学表现。方法 分析我院一例原发性纵隔非典型脑膜瘤的临床表现、实验室检查、影像学及病理学特征,并结合文献进行回顾,总结该病的临床、病理及影像学特征。结果 患者进行实验室及影像学检查后,行纵隔肿物切除术,术后恢复良好。结论 原发性纵隔非典型脑膜瘤的组织来源及结构与颅内钙化型脑膜瘤一致,故有脑膜瘤的影像学特征,熟悉其影像学特征及病理改变,有助于对该病的诊断及鉴别诊断。     

同时性双侧原发性乳癌1例

患者　女 ,5 0岁。因发现双侧乳腺肿块 2个月入院。体查 :双侧乳腺外型不对称 ,右侧比左侧稍大。皮肤无“桔皮样”改变 ,乳头无凹陷及溢液。右乳腺外上象限及左乳晕下分别可触及一 4ｃｍ× 3ｃｍ及3ｃｍ× 2ｃｍ大小的肿块 ,表面欠光滑 ,边缘不规则 ,质硬 ,与皮肤均有轻度粘连 ,与胸大肌无粘连 ,活动度稍差 ,无明显触压痛。左腋窝未触及肿物。右腋窝可触及一花生米粒大小淋巴结。光滑 ,质硬 ,无明显触压痛。双侧乳腺其他部位未触及肿大淋巴结。诊断 :双侧乳腺肿物性质待查。予以手术治疗。先在局麻下行双侧乳腺肿物切除送快速冰冻切片 ,病理…     

A case of primary anterior mediastinal embryonal carcinoma: report of a case]

A 15-year-old man was admitted to our hospital because of chest pain. The chest x-ray film and CT scan revealed a large anterior superior mediastinal mass. The serum alpha-fetoprotein (AFP) value was raised. Percutaneous biopsy of the tumor suggested embryonal carcinoma. The tumor was totally removed. Postoperatively combination chemotherapy including CDDP was performed. However the patient died of tumor recurrence 8 months after operation. AFP is very useful for its diagnosis and the follow-up of the clinical course.     

Peripheral intrapulmonary lipoma: a case report

Lipomas are common benign neoplasms but they rarely occur in visceral organs. Pulmonary lipomas are rare, and most of them are seen in endobronchial localization. Peripherally located pulmonary lipomas are extremely uncommon. There are only eight cases reported in the literature and only one of the patients was female. Our case is the second peripheral pulmonary lipoma in a female patient. The patient is a 38-year old female, who has an incidentally found solitary pulmonary nodule, revealed by X-ray, during routine check-up procedure. A 1.5 cm diameter soft tissue mass was seen in the superior segment of the lower lobe of right lung in computerized thorax tomography. Wedge resection was performed with frozen section evaluation. Histopathologically the well-circumscribed lesion consisted of mature adipose tissue, containing areas of myxoid degeneration, organized as lobules surrounded by respiratory epithelium. The lesion was diagnosed as lipoma. Radiological imaging techniques have high sensitivity detecting the solitary pulmonary lesions but their ability to give information about their nature is limited. Although they are rare, intrapulmonary lipomas should be considered in the differential diagnosis of solitary pulmonary nodules. Wedge resection with frozen section evaluation seems to be the best choice for both diagnosis and treatment.     

A case of primary mediastinal seminoma

Primary mediastinal seminoma is a rare clinical entity. Because of its high malignancy, we often find it only when it grows very large so we can't resect it completely. Our patient came with asthma attack and abnormal shadow on chest X-ray was pointed out. Germinal cell tumor was diagnosed by thoracoscopy and resection of the tumor was performed. Postoperative radiation therapy also was performed. Our case is alive in good health for 1 year postoperatively and good prognosis will be expected.     

Synchronous metastatic seminoma and primary retroperitoneal ganglioneuroma: case report and literature review

Testicular cancer is the most common malignancy in young men with seminomas comprising almost half of all germ cell tumours. Benign ganglioneuromas are rare tumours derived from the sympathetic nervous system. They usually occur in aldolescents and young adults and are predominantly located in the mediastinum and retroperitoneum. We report a case of a patient with synchronous metastatic testicular seminoma with retroperitoneal lymph node involvement and a benign retroperitoneal ganglioneuroma (RGN) which caused diagnostic and management challenges. The patient had a complete response following combination chemotherapy for his seminoma and subsequently underwent complete resection of his ganglioneuroma.     

Giant primary mediastinal hydatid cyst causing Horner's syndrome: report of a case

As the liver and the lungs are the most common sites for hydatid cysts, a primary mediastinal involvement is quite rare. The symptoms related to primary mediastinal hydatid cysts usually depend on the size, location and compression to nearby structures. Presenting a 51-year-old male patient with the symptoms of Horner's Syndrome, we draw attention to a rare complication of a giant primary mediastinal hydatid cyst and its challenging management.     

A case of primary intrapulmonary neurilemoma and review of the literature

In this paper, we present an extremely rare case of a primary intrapulmonary neurogenic tumor, in which localization of S-100 protein, neuron specific gamma-enolase (NSE) and CEA was investigated using immunohistochemical staining. The patient, who was a 39-year-old man, experienced no symptoms; however, a routine chest X-ray revealed a round tumor-like shadow in the infrahilar area of the right lung. As the tumor appeared to be gradually increasing in size, surgery was performed and histopathological examination of the excised tumor revealed it to be a primary intrapulmonary neurilemoma. Immunohistochemical staining demonstrated the presence of S-100 protein in the tumor cells but NSE and CEA were not detected. For the 2 years following his operation, the patient has been in good health and is now under careful observation.     

Paraesophageal mediastinal desmoid tumor: case report

A 45-year-old man presented with dysphagia. Computed tomography and magnetic resonance imaging showed an abnormal shadow in the paraesophageal mediastinum, which a thoracoscopic biopsy revealed to be a desmoid tumor that had infiltrated the surrounding tissues. We attempted esophageal stent placement; however, the esophageal stenosis could not be dilated, and bypass surgery was performed first, with tumor resection postponed, and radiation and hormonal therapy were added. Mediastinum desmoid tumors are rare, with only 22 other cases reported in the English language literature. Herein, we report the details of our patient and provide a review of other cases.     

A case of primary intrapulmonary neurilemoma and review of the literature

In this paper, we present an extremely rare case of a primary intrapulmonary neurogenic tumor, in which localization of S-100 protein, neuron specific γ-enolase (NSE) and CEA was investigated using immunohistochemical staining. The patient, who was a 39 year old man, experienced no symptoms, however, a routine chest X-ray revealed a round tumor like shadow in the infrahilar area of the right lung. As the tumor appeared to be gradually increasing in size, surgery was performed and histopathological examination of the excised tumor revealed it to be a primary intrapulmonary neurilemoma. Immunohistochemical staining demonstrated the presence of S-100 protein in the tumor cells but NSE and CEA were not detected. For the 2 years following his operation, the patient has been in good health and is now under careful observation.     

A case report of mediastinal cystic lymphangioma

Mediastinal lymphangioma is very rare in the literature. A resected case of mediastinal cystic lymphangioma was reported. A 41-year-old man admitted to our hospital complaining of sore throat. A chest X-ray examination showed a large mediastinal mass on the right. At the right thoracotomy, a large cystic mass filled the anterior mediastinum and extended from the thoracic inlet to the posterior costophrenic angle. The cyst contained about 600 ml yellowish brown fluid and was adherent to the surrounding tissue, especially to the aorta and the left main bronchus. The resected tumor was 20 x 12 x 10 cm in size and 620 g in weight. Histological diagnosis was cystic lymphangioma. The patient is alive and well 26 months later, and there is no sign of recurrence of the tumor.     

同时性原发双侧不同组织类型乳腺癌1例

1 临床资料患者,女,70岁.因双侧乳房无痛性肿块10个月,于2009年4月2日入院.有乳腺癌家族史(其母死于乳腺癌肺转移).体检:双侧乳房视诊尚对称,双乳头无溢液,右侧乳头轻度凹陷,双乳皮肤无橘皮样改变.     

Synchronous primary gastric cancer and renal cell carcinoma: A case report and literatures review

A 73-year-old woman was admitted and treated because of epigastric fullness, palpitation, and tarry stool for 2 days. Gastric cancer was found via panendoscopy. A preoperative abdominal computed tomographic scan revealed a hypervascular mass in the left kidney; renal cell carcinoma (RCC) was the initial impression. A concomitant surgery for subtotal gastrectomy and radical left nephrectomy was performed. The pathological examination confirmed gastric adenocarcinoma (T2a) and RCC (T2b). Convalescence was uneventful and she was discharged in stable condition. There was no evidence of tumor recurrence at a 20-month follow-up examination. Elderly people with early gastric cancers have a relative higher probability of developing a synchronous tumor than younger people. The incidence of synchronous gastric cancer and RCC is quite low, and concomitant surgery is rare. Surgeons need to be aware of the possibility of a synchronous second primary cancer when the initial gastric cancer is diagnosed. A concomitant surgery for gastrectomy and radical nephrectomy can be safely performed in selected patients, which can achieve feasible oncological control.