乳腺增生患者期门穴与非穴位对照点红外辐射光谱比较

目的:比较乳腺增生病患者双侧期门穴与非穴位对照点体表红外辐射光谱的差异。方法:采用高灵敏度PHE201体表红外光谱仪,检测68名乳腺增生病患者左、右期门穴与非穴位对照点体表1.5~16μm波段的红外辐射光谱。结果:乳腺增生病患者左期门穴在检测的59个波长点中有49个点(3.50、4.00、4.50~16.00μm)红外辐射强度明显高于与非穴对照点(P<0.05);右期门穴在检测的59个波长检测点中有48个点(1.75、3.50、4.00、4.50~6.50、7.00、7.50~16.00μm)红外辐射强度明显高于与非穴对照点(P<0.05)。结论:期门穴红外辐射强度增高,一定程度上反映了乳腺增生病肝气郁滞的病理本质。     

Efficacy of moxibustion by stimulating acupoints of Danzhong(CV 17) and Ganshu(BL 18) on hyperplasia of mammary gland in rats

OBJECTIVE: To evaluate the efficacy of moxibustion, through stimulating acupoints of Danzhong(CV 17) and Ganshu(BL 18) in rats with hyperplasia of mammary gland(HMG) which induced by estrogen and progestogen.METHODS: Thirty female Sprague-Dawley rats were randomly divided into saline control group,HMG model group, and HMG moxibustion group with 10 in each group. Saline control was the group injected by saline. HMG model were created by injection of estrogen and progestogen. Moxibustion group was also injected of estrogen and progesto-gen with moxibustion at the same time. The Changes of nipple diameter and height were measured.The rats' skin temperature was recorded by an infrared thermal camera at the nipples, mammary areas,Danzhong(CV 17) and Ganshu(BL 18). Pathological changes of mammary gland in rats were also observed under light microscope.RESULTS: The diameter and height of the nipples in model group were prominently bigger and higher than that in control group(P 0.01). The diameter and height in moxibustion group were prominently smaller and lower than that in model group(P 0.01), and there was no significant difference between moxibustion group and control group.Compared with control group, skin temperature of the nipples, mammary area, and acupoints Danzhong(CV 17) and Ganshu(BL 18) decreased prominently in model group(P 0.01-0.05). Compared with model group, skin temperature of that in moxibustion group increased prominently(P 0.05).CONCLUSION: Treatment with moxibustion can effectively decrease the HMG rats' nipple diameter and height, and increase the skin temperature in HMG model rats at the nipples, mammary areas,Danzhong(CV 17) and Ganshu(BL 18). This study convinces the therapeutic effect of moxibustion on mammary gland hyperplasia.     

乳腺增生病与乳腺癌术后患者关元穴体表红外光谱比较

目的:比较乳腺癌术后患者与乳腺增生病患者任脉经穴关元穴体表红外辐射光谱特性。方法:采用高灵敏度PHE201体表红外光谱仪,观察了29例乳腺癌术后患者与30例乳腺增生病患者关元穴1.5～16μm波段体表红外辐射光谱的差异。结果:乳腺癌术后组与乳腺增生病组关元穴红外辐射强度不同,乳腺癌术后组关元穴红外辐射强度低于乳腺增生病组;在59个波长检测点中,21个波长检测点(3.0μm,10.25～14.25μm,14.75μm,15.75μm,16.0μm),差异具有统计学意义(P0.05)。结论:关元穴红外辐射强度的差异可能与乳腺癌的发生仅仅是全身进行性疾病的局部表现,虽然病理组织切除了,但体质并未改善有关。     

乳腺增生病不同证型关元穴红外辐射光谱探讨

目的:比较乳腺增生病患者不同证型任脉经穴关元穴体表红外辐射光谱特性。方法:采用高灵敏度PHE201体表红外光谱仪,观察了60例乳腺增生病患者不同证型关元穴1.5～16μm波段体表红外辐射光谱的差异。结果:乳腺增生病肝郁痰凝型患者与冲任失调型患者比较,两组关元穴体表红外辐射强度存在显著性差异。具有统计学意义差异的波段为:1.5～2.25μm,2.75μm,3μm,3.5μm,3.75～5μm,6～6.5μm,7μm,7.75μm,10.5～14μm,(P<0.05)。结论:关元穴红外辐射强度的差异可能与乳腺增生病不同证型有关。     

Infrared radiation temperature comparison on body surface of points between healthy people and patients with hyperplasia of mammary glands

目的：比较乳腺增生病患者与正常人穴位体表红外辐射温度的差异。方法：采用ThermaCAMTMP30红外热像仪，检测74名乳腺增生病患者和63名身体健康，无乳腺增生病的正常人四条经脉八个穴位的体表红外辐射温度。结果：乳腺增生病患者右幽门穴的体表红外辐射温度显著高于正常人的右幽门穴的体表红外辐射温度（P=0．009）.左幽门穴及所测其余各穴的红外辐射温度患者与正常人无明显差异（P〉0.05）.结论：乳腺增生病患者与正常人右幽门穴的红外辐射温度有显著差异，这种差异可能与乳腺增生病的病才暇幽门穴的特异性有关。     

穴位贴敷法治疗乳腺增生病疗效观察

目的观察穴位贴敷法与中药治疗乳腺增生病的疗效差异.方法将63例女性患者随机分为穴贴组(33例)、药物组(30例).穴贴组用穴位贴敷法(将三棱、莪术、制南星、冰片制成薄片,敷于气海、关元及乳房局部阿是穴);药物组口服乳癖消.结果经过3个疗程治疗,穴贴组总有效率为97.0%,药物组总有效率为83.3%,穴贴组疗效优于药物组(P＜0.05).穴贴组乳房疼痛改善积分为(13.82±5.90)分,药物组为(7.00±3.89)分,2组比较差异有非常显著性意义(P＜0.01).结论穴位贴敷法治疗乳腺增生病的疗效肯定.     

“益气调血,扶本培元”针刺法对正常老年人脑区葡萄糖代谢的影响

目的通过观察＂益气调血,扶本培元＂组穴对正常健康老年人脑葡萄糖代谢的影响,为针刺效应和特异性研究提供影像学依据。方法选择10例正常老年人随机分为穴位组和非穴组。治疗组取膻中、中脘、气海、血海、外关、足三里穴,对照组取上述穴位旁开的非经非穴点进行针刺研究,每天1次,每星期5次,连续进行8星期。治疗前和治疗8星期后所有患者均接受正电子发射型计算机断层显像（PET）脑功能成像检查,观察针刺前后感兴趣脑区葡萄糖代谢变化特征。结果针刺8星期后穴位组双侧额叶和双侧海马区葡萄糖代谢较针刺前均明显升高（P〈0.05）,非穴组针刺前后无明显变化;两组比较8星期后治疗组双侧额叶和左侧颞叶葡萄糖代谢均明显高于非穴组（P〈0.05）。结论 ＂益气调血,扶本培元＂组穴可以提高正常老年人认知相关脑区葡萄糖代谢,且具有显著的腧穴特异性。     

针刺配合灸法治疗慢性疲劳综合征的临床随机对照研究

目的:观察、对比针刺法及针加灸法治疗慢性疲劳综合征(chronic fatigue syndrome,CFS)的临床疗效。方法:将133例CFS患者随机分为3组,即针刺组(n=47)、针加灸组(n=44)及非穴组(n=42)。针刺组予针刺百会、膻中、气海、关元、足三里、合谷、太冲、三阴交治疗;针加灸组予膻中、合谷、太冲、三阴交针刺治疗,百会、气海、关元、足三里温针灸治疗;非穴组在上两组所选腧穴周围1~2cm非腧穴点给予针刺。均留针30min,每日1次,10次为一疗程,共治疗2个疗程。应用Chalder疲劳量表和患者满意度自评量表对治疗后疲劳改善情况及治疗效果给予评估。结果:(1)疲劳积分改善情况:与治疗前比较,针刺组及针加灸组治疗后体力疲劳积分、脑力疲劳积分及疲劳总积分显著降低(P0.05,P0.01);与非穴组相比,治疗后针刺组及针加灸组上述3项指标显著降低(P0.05,P0.01);治疗后针加灸组的体力疲劳积分及疲劳总积分显著低于针刺组(P0.05)。(2)各组临床满意度比较:针加灸组满意率明显高于针刺组和非穴组(P0.05),而针刺组与非穴组相比差异无统计学意义(P0.05)。结论:无论单纯针刺法或温针灸法治疗CFS均具有良好的疗效,二者相比,又以温针灸法更优。     

Infrared radiation spectrum of acupuncture point on patients with coronary heart disease

The objective of this study was to compare the acupoint infrared radiation spectrums of patients and healthy volunteers to show whether those of coronary heart disease (CHD) patients carry distinctive pathological information. PHE201, using a highly sensitive infrared spectrum detection device applied to the acupoint Neiguan (PC6) and to a control point on 50 CHD patients and 47 healthy adults. A total of 73 wavelength spots were detected. The scanned wavelengths ranged from 1.5 microm to 16 microm, and the scanning spacing was 0.2 microm. The data were automatically recorded in the database of the device for statistical analysis. Infrared radiation intensities of 23 in the 73 detected wavelength spots significantly differed in the CHD patients' Neiguan as compared to those of the healthy subjects (from p=0.048 to p=0.002), while only 12 wavelength spots at a non-acupuncture control point showed significant differences. By the chi(2) test, these differences between Neiguan and the non-acupuncture control point are statistically significant (p=0.033). At 2-2.5 microm, which is related to energy metabolism, the intensity at the CHD patients' Neiguan was significantly lower than that of the healthy adults (from p=0.026 to p=0.017). No difference was observed at the non-acupuncture control point (from p=0.094 to p=0.052). The data suggest that the changes of infrared spectrum at Neiguan in coronary heart disease patients may reflect the distinct pathological changes. This may be the result of hypoactive energy metabolism in the area of the acupoint.     

"屋翳"穴与多穴针刺对乳腺增生病模型大鼠乳腺腺体的影响

目的:以乳腺增生病病理形态计量学为标准,筛选治疗乳腺增生病的关键穴位。方法:将Wistar未孕雌性大鼠48只随机分为正常组、模型组、单穴(屋翳)组、多穴组。除正常组外,以苯甲酸雌二醇0.5 mg/kg每日腹腔注射,25 d后改为每日腹腔注射黄体酮4 mg/kg,连续5 d,复制乳腺增生病模型。单穴组取“屋翳”穴,多穴组取“屋翳”“膻中”“合谷”“足三里”穴,每日针刺1次,留针5 min,9次为1疗程,共针刺3个疗程。治疗结束后取大鼠第2对乳房做病理切片,HE染色,镜下观察;美国IPP图像分析软件分析腺泡腔直径及面积。结果:模型组乳腺导管扩张,腺泡腔直径及面积均较正常组增大(均P<0.01);单穴组、多穴组腺泡腔直径及面积较模型组减小(P<0.01);单穴组与多穴组腺泡腔直径及面积无显著性差异(P>0.05)。结论:针刺“屋翳”穴可明显抑制雌激素注射引起的乳腺增生,说明“屋翳”穴是治疗乳腺增生的关键穴位。