慢性宫颈炎微波治疗临床观察

目的：探究微波对治疗慢性宫颈炎的作用和疗效。方法：将我院2008年5月至2009年12月300例慢性宫颈炎患者分为治疗组和对照组，治疗组采用微波治疗，对照组单纯进行药物治疗。结果：治疗组有效率为92．13％，对照组的有效率为74．5％，两组相比较，有效率存在显著差异；治疗组治愈率高达64．5％，而对照组治愈率仅为32．0％，治愈率方面也存在显著的差异。结论：微波治疗的结果，明显好于药物治疗，充分体现其优越性，是比较理想的治愈慢性宫颈炎的方法，应在临床治疗中重视并椎广。     

药物循环结合宫颈微波综合治疗慢性子宫颈炎临床评价

目的：研讨药物循环结合宫颈微波用于慢性宫颈炎的临床治疗效果。方法：回顾性分析2014年7月－2015年7月期间，我院收录的60例慢性宫颈炎患者资料，对其展开分组讨论。随机分为对照组、观察组，每组30例，对照组采用药物循环治疗法，观察组采用“药物＋宫颈微波”综合疗法，于1个月后回访调查，对比观察组、对照组2种治疗效果；按照痊愈、显效、有效、无效等进行对比，统计疗效结果的差异性（P＜0．05）。结果：慢性宫颈炎以白带增多、疼痛、肠道症状、月经不调、痛经为主要症状，本次对照组治共26例有效，总有效率86．7％，对照组总有效30例，总有效率100％；两组症状前后对比差异明显（P＜0．05）。结论：药物循环结合宫颈微波治疗慢性宫颈炎效果更显著，临床值得积极推广此方式。     

LEEP刀联合纳米银治疗慢性宫颈炎疗效观察

目的探讨宫颈电热圈环切除术联合纳米银治疗慢性宫颈炎的临床疗效。方法将158例慢性宫颈炎患者，随机分为LEEP刀联合纳米银组（试验组）88例，单用LEEP刀组（对照组）70例。比较两组的疗效，不良反应。结果试验组的总有效率为97．7％，与对照组的总有效率81．4％，有显著性差异（P〈0．01）。结论LEEP2LI联合纳米银治疗慢性宫颈炎的效果显著，副反应小，临床效果优于单用LEEP刀。     

微波、治糜灵栓对慢性宫颈炎的治疗与护理观察

目的观察比较微波、治糜灵栓对慢性宫颈炎患者的治疗效果。方法慢性宫颈炎患者302例分别采用微波、治糜灵栓治疗并加强护理。结果微波两次治疗总有效率98．69％，治糜灵栓两疗程治疗有效率75．17％。结论微波治疗慢性宫颈炎疗效满意，治糜灵栓治疗慢性宫颈炎疗效较满意，两种治疗方法有效率差别具有显著意义（P〈0．01）。     

综合治疗慢性盆腔炎100例疗效观察

目的观察慢性盆腔炎综合治疗的临床疗效。方法150例慢性盆腔炎的患者随机分为两组，观察组100例为综合治疗组，用抗生素＋中药＋微波联合；对照组为单纯药物治疗组，用两种以上联合抗生素＋糜蛋白酶，对两组疗效进行比较。结果观察组治愈率91％，总有效率100％；对照组治愈率64％，总有效率86％，经X^2检验统计处理，P〈0．05，两组疗效差异有显著性，观察组总有效率和治愈率明显高于对照组。结论抗生素＋中药＋微波综合治疗慢性盆腔炎疗效确切，治愈高，无复发和不良反应，易为患者接受。     

微波联合银尔舒治疗慢性宫颈炎的临床疗效探讨

目的：总结慢性宫颈炎的临床特征，探讨微波联合银尔舒治疗慢性宫颈炎的临床疗效。方法：选取2013年06月～2014年07月我院收治的慢性宫颈炎病例80例，随机将其分成实验组40例，对照组40例，对照组单纯应用微波治疗，实验组应用微波联合银尔舒治疗，比较疗效。结果：实验组慢性宫颈炎病例阴道出血量为（17．45±2．06）ml，KPS 评分为（84．65±5．63）分，QLQ －C30评分为（81．65±8．62）分，疾病治疗有效率为90．0％，均优于对照组（P＜0．05）。结论：微波联合银尔舒治疗慢性宫颈炎，效果满意，值得进一步应用。     

微波联合保妇康栓治疗宫颈炎疾病的可行性研究

目的：研究微波联合保妇康栓治疗宫颈炎疾病的可行性。方法：试验对象：该院近2年收治的83例宫颈炎疾病患者。患者分组方法：掷硬币法。83例患者分为微波组和微波＋药物组两个组别。微波组以单纯微波治疗;微波＋药物组以微波联合保妇康栓治疗。观察指标：（1）宫颈炎治愈率和总有效率;（2）副作用发生率。结果：（1）微波＋药物组相比于微波组宫颈炎治愈率和总有效率更高,差异显著（P＜0.05）;（2）微波＋药物组、微波组副作用发生率接近,无统计学差异显著（P＞0.05）。结论：微波联合保妇康栓治疗宫颈炎疾病的可行性高,可有效改善患者临床症状,作用安全,值得推广。     

微波疗法结合干扰素用于慢性宫颈炎治疗临床分析

目的：探究微波疗法结合干扰素用于慢性宫颈炎治疗的临床效果。方法：选取2015年上半年在该院进行慢性宫颈炎治疗的78例患者，分为 A 组及 B 组，A 组采用微波联合干扰素治疗，B 组采用单独干扰素治疗，比较其治疗效果及不良反应、复发情况。结果：A 组有效率为92.31％，B 组为71.79％，A 组较高（P ＜0.05），A 组不良反应发生率为10.26％，B 组为23.08％，A 组较低（P ＜0.05），且 B 组复发率为17.95％，高于 A 组的10.26％。结论：采用微波联合干扰素对慢性宫颈炎患者进行治疗，可有效改善患者症状，临床疗效较高，同时治疗后出现不良反应或复发情况较少。     

慢性宫颈炎采用药物和微波治疗的临床治疗效果对比研究

目的：对比采用药物和微波治疗慢性宫颈炎的临床治疗效果。方法：选择该院2013年10月至2015年03月收治的慢性宫颈炎患者68例，采用单双号随机分组法，单号为观察组，双号为对照组，每组各34例。对照组患者给予药物治疗、观察组给予微波治疗。对比两组患者总有效率。结果：两组慢性宫颈炎患者治疗后各项指标对比表示：观察组患者的总有效率为（94.12％）均明显高于对照组患者（73.53％，P ＜0.05）。结论：针对慢性宫颈炎患者，使用微波治疗的效果较为明显，治疗的总有效率高，值得在临床上推广。     

微波联合重组人干扰素α-2b凝胶治疗慢性宫颈炎效果观察

目的：探讨微波联合重组人干扰素α-2b凝胶治疗慢性宫颈炎的临床效果。方法慢性宫颈炎患者200例根据治疗方法不同分为两组,观察组接受微波联合重组人干扰素α-2b凝胶治疗,对照组仅接受微波治疗,比较两组的疗效。结果观察组治疗总有效率99．0％,高于对照组的88．0％（ P ＜0．01）;观察组复发率低于对照组（ P ＜0．01）,阴道流血和排液持续时间均短于对照组（ P ＜0．01）。结论微波联合重组人干扰素α-2b凝胶治疗慢性宫颈炎有助于提高治疗效果,降低复发率,减少阴道流血和排液,是治疗慢性宫颈炎较好的方法。     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

BLOOD PRESSURE CHANGE WITH AGE IN SALT-SENSITIVE TEENAGERS

Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P＜ 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P＜ 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.     

安心颗粒对急诊经皮冠状动脉介入术后生活质量影响的研究

目的：评价使用安心颗粒对急诊经皮冠状动脉介入术（PPCI）术后生活质量的影响.方法：将160例接受PPCI的急性ST段抬高型心肌梗死患者随机分为安心颗粒组（术前顿服安心颗粒8.8g,术后安心颗粒4.4 g/次,每日2次）和对照组（仅接受基础药物治疗）.所有患者均服用阿司匹林、氯吡格雷和阿托伐他汀.分别在入院时、出院前1d、出院后180 d时,应用心肌梗死多维度量表（MIDAS）、中文版SF-36评价量表对患者生活质量评分.并观察术后30 d以内的出血并发症、血小板减少症发生情况.结果：入院时和出院前1d,两组患者的心肌梗死MIDAS、SF-36量表评分比较无差异（P＞0.05）;出院后180 d时,与对照组比较,安心颗粒组MIDAS、SF-36评分明显减低（P＜0.05）;组内与入院时比较,两组出院前1d、出院后180 d时,MIDAS、SF-36评分均降低（P＜0.05）.两组患者在随访期间均无大量出血、少量出血、重度和极重度血小板减少症发生,安心颗粒组有4例、对照组有7例发生不明显出血（P＞0.05）.两组发生轻度血小板减少症的患者数比较无差异（P＞0.05）.结论：PPCI使用安心颗粒,能改善急性ST段抬高型心肌梗死患者的生活质量,且不增加出血风险.     

The comparative studies of the influences of Urapidil and Nicardipine on sino-atrial node function, atrio-ventricular node function and hemodynamics

Objective:To investigate the influences of urapidil and nicardipine on rabbit sinus function,atrio-ventricular node function and hemodynamics.Methods:Thirty-two Angora's rabbits were selected and randomly divided into four groups.U1 group:urapidil 0.25 mg/kg;U2 group:urapidil 0.5 mg/kg;N1 group:nicardipine 10 μg/kg;N2 group:nicardipine 20 μg/kg.All these medicine were administrated within 30 seconds.Measurements were taken before and after the administration of urapidil or nicardipine for the following data:mean blood pressure(MAP),heart rate(HR),sino-atrial conduction time(SACT),maximal sinoatrial recovery time(SNRTmax)corrected sinus node recovery time(CSNRT),index of sinus node recovery time(SNRTI),Wenckebach A-V conduction frequency (WB),and P-R interval.Results:Significant MAP and HR changes were identified in all of the four groups before and after administration of both urapidil and nicardipine.No significant changes could be found in the rest of the parameters.Intergroup analysis showed that SACT and CSNRT of N1 and N2 groups were shorter than those of the U2 group(P＜0.01);the MAP decreased(P＜0.01)and the HR increased drastically(P＜0.01).Conclusions:Neither urapidil(0.25 mg/kg,0.5 mg/kg)nor nicardipine(10μg/kg,20μg/kg)has any significant influence on rabbit sinus function or rabbit atrio-ventricular node function.Nicardipine could be a better choice than urapidil for parafunctional sinus node patients.     

Expression of OPGmRNA and ODFmRNA in the patients of hip fracture due to osteoporosis

Objective：To investigate the gene expression of osteoprotegerin（OPG） and osteoclast differentiation factor（ODF） in the bone tissue of patients with hip fracture due to osteoporosis. Methods：OPGmRNA and ODFmRNA in the bone tissue in 50 cases of osteoporosis sufferers（over 50 years old） with hip fracture（Observer Group） and 30 cases of hip facture sufferers with no osteoporosis（Control group） were analyzed with the Semi-Quantitative RT-PCR method. Results：The mRNA expressed of ODF, OPG were both high in the patients with hip fracture. In the control group, the expression of OPG mRNA was observed, while the expression of ODF mRNA was very slight. Conclusion：Aged patients contained all signals including OPG, ODF that are essential for inducing osteoclastogenesis and promoting bone resorption.     

The clinicopathological and immuohistochemical analysis of solid-pseudopapillary tumor of the pancreas： report of 9 cases

Objective：To investigate the clinical features, pathological characteristics and immunophenotype of solid-pseudopapillary tumor of the pancreas（SPTP）. Methods：Nine surgically treated cases of SPTP were retrospectively reviewed. Hematoxylin and Eosin（HE） staining and immunohistochemical staining were used to analyze all cases, and the general clinical data was collected. Results：Six patients were asymptomatic except for a palpable mass. Two patients complained of vague-epigastric pain. One patient appeared jaundice. The tumor was encapsulated and solid tissues alternately with cystic tissues. Histologically, the histological structure of solid portion was pseudopapillary with a fibrovascular core. Tumor cells were uniform and medium-sized which were arranged in sheets ets or nests or pseudopapillary patterns. Immunohistochemical studies demonstrated that SPTP proved positive in vimentin（9/9 cases）, AAT（9/9 cases）, NSE（9/9 cases）, ACT（7/9 cases）, CK20（2/9 cases）, CgA（1/9 cases）, S-100（3/gcases）, PR（4/gcases）, Syn（3/9 cases） and CD56（5/9cases）, negative in CEA and ER. Conclusion：SPTP is a tumor predominantly occurring in young women frequently without special symptoms. This tumor has various characteristical histological patterns with different immunophenotype.     

Dynamic Changes in Serum Estradiol and Progesterone levels in Patients of Premenstrual Syndrome with Adverse Flow of Liver-qi

Objective:To probe into the influence of changes of ovarian hormones on the pathogenesis of the specific sub-type premenstrual syndrome(PMS)and reveal partial microcosmic mechanisms of adverse flow of liver-qi.Methods:Estradiol(E2)and progesterone(P)levels in serum were determined at different phases of menstrual cycle by radioimmunoassay.Results:In the group of PMS with adverse flow of liver-qi.the secretive peak value Of E2 and P at the follicular phase significantly decreased,and the secretive peak value at the luteal phase did not come into being.Conclusions:Low E2 and P secretive peak at the follicular phase and absence of secretive peak at the luteal phase is one of the microcosmic mechanisms of PMS with adverse flow of liver-qi.One of the pathophysiologic mechanisms of specific sub-type PMS is probably the continuous low level of E2and P.     

Real-time Three-dimensional Echocardiography in Assessment of Left Ventricular and Right Ventricular Volumes

Real-time three-dimensional echocardiography (RT3DE)is a new ultrasound technique that enables dynamic threedimensional visualization and quantification of the heart in real time. Investigation of feasibility and methodology of RT3DE in determining left ventricular (LV) and right ventricular (RV) volumes, RT3DE was performed in 35 normal adults using Philips SONOS 7500 system with a 2-4 MHz matrix array transducer. The 60°×60° "pyramid" volume database was obtained and analyzed on a TomTec echo workstation. Both LV and RV volumes were calculated with four 3DE methods (i.e. apical 2, 4, 8, and 16-plane) through manually tracing ventricular endocardial borders in end diastole and end systole. Stroke volumes were then calculated. LV volume was also measured by 2DE Simpson's rule using GE VIVID 7 ultrasound machine.     

SCREENING FOR A 21-CHROMOSOME ABNORMALITY IN PREIMPLANTED EMBRYOS OF ELDERLY WOMEN

Increasing maternal age is the only etiological factor unequivocally linked to Down's syndrome in humans. The occurrence rate of newborns with Down's syndrome is about 1/220 in women over 35 years old. However, the occurrence rate in embryos fertilized in vitro, of the elder woman is unclear. Using FISH we screened the number of chromosome 21 in preimplanted embryos of 5 elderly women (average age, 38.4 years) to study the feasibility and necessity of screening trisomy 21 in embryos in patients over 35 years old at the in vitro fertilization (IVF) center.