~(99m)Tc-ECD脑显像定量分析对小儿原发性癫痫病灶定位诊断的研究

目的：采用相对定量分析法评估９９ｍＴｃ－ＥＣＤ脑血流灌注显像对小儿原发性癫痫定性和病灶定位的诊断价值。方法：２１例ＣＴ检查正常的小儿原发性癫痫病人进行９９ｍＴｃ－ＥＣＤ脑显像和相对定量分析，并同步进行ＥＥＧ检查。结果：２１例病人ＳＰＥＣＴ显像１８例异常，３例正常，阳性率８５７％，假阴性１０％，１８例脑显像异常患儿中，１６例局部脑血流（ｒＣＢＦ）减少，９９ｍＴｃ－ＥＣＤ摄取率７２６±８９％，２例在额叶有限局性ｒＣＢＦ增加，９９ｍＴｃ－ＥＣＤ摄取率分别为１４９５％和１３０９％。ＥＥＧ检查２１例病人２０例异常，１例正常，阳性率９５２％，能定位诊断的７例，定位率为３５％。结论：９９ｍＴｃ－ＥＣＤ脑显像相对定量分析法对小儿原发性癫痫病灶的定位有临床意义，优于ＥＥＧ。     

冷诱导心肌SPECT与UCG对诊断系统性硬皮病心肌损害的 …

目的：探讨ＳＰＥＣＴ心肌显像和超声心动图（ＵＣＧ）冷诱导对诊断系统性硬皮病（ＳＳＣ）心肌损害的临床价值。方法：应用＾９９ｍＴｃ－ＭＩＢＩ对２３例ＳＳＣ病人进行ＳＰＥＣＴ心肌显像冷诱导,并同期进行ＵＣＧ冷诱导检测。结果：（１）１４例病人（６０．９％）,至少有一处心肌放射性分布异常,４例病人（１７．４％）于ＵＣＧ示局部室壁运动低下,Ｐ〈０．０５。（２）ＳＰＥＣＴ阳性率在雷诺现象（ＲＰ）组和无ＲＰ组之间     

结核性渗出性胸膜炎的超声诊断

结核性渗出性胸膜炎的超声诊断湖北省谷城县人民医院Ｂ超室韩大国本文报告采用超声显像对３４例结核性渗出性胸膜炎患者进行了检查，３１例胸膜呈均匀性增厚，一般在１ｃｍ以内，９例胸膜表面上显示有弥漫性结节性病灶。在大量的胸腔积液内２３例显示有活动性漂浮带或吹风...     

~(99m)Tc-EC核素动态显像在泌尿外科的应用

９９ｍＴｃ－ＥＣ核素动态显像在泌尿外科的应用王祖镔①马云川从１９９４年９月开始我们在泌尿外科疾患的诊断中，把９９ｍＴｃ－ＥＣ核素泌尿系动态显像做为主要的检查方法之一，结果满意，现报告如下。１临床资料与方法本文患者２２８例，男１５６例，女７２例，年龄１...     

B超及CDFI和ECT对5cm以上肝血管瘤的对照研究

Ｂ超及ＣＤＦＩ和ＥＣＴ对５ｃｍ以上肝血管瘤的对照研究山西医学院第二附属医院山西医学院第二附属医院功能科杜联芳，雷成功，赵惠英邮政编码０３０００１本文应用二维超声（Ｂ超）、彩色多普勒血流显像（ＣＤＦＩ）和发射型计算机断层（ＥＣＴ）对３２例５ｃｍ以上的肝...     

乳腺肿块99mTc-MIBI显像的临床价值

本文研究了９９ｍＴｃＭＩＢＩ核素显像判别乳腺肿块良恶性的临床价值。１　资料与方法本文９１例患者中,女８９例、男２例,年龄２３～７９岁,平均年龄４８岁。全部病人乳腺检查触诊检查均发现肿块,肿块大小１～１０ｃｍ。９１例患者手术后全部作病理切片检查。核素显像：核素显像检查在手术前１周内进行,病人仰卧于检查床上,双手上举抱头,静脉注射９９ｍＴｃＭＩＢＩ５５５～７４０ＭＢｑ（１５～２０ｍＣｉ）后５ｍｉｎ即行早期乳腺正侧位显像,３０ｍｉｎ后作延迟显像。显像仪器为ＥｌｓｃｉｎｔＡＰＥＸＳＰ４ＨＲＳＰＥＣ…     

单光子发射计算机断层显像对儿童癫痫病诊断价值的探讨

目的：研究单光子发射计算机断层显像（ＳＰＥＣＴ）在癫痫病诊断中的应用价值并与癫痫发作间期ＥＥＧ对照。方法：对７０例癫痫发作间期必进行ＳＰＥＣＴ检查,结果对三维图像进行目测分析,连续２个以上层面出现放射性显示ｒＣＢＦ明显者为阳性结果：７０例癫患儿发作间期（发作７２ｈ后）检查,显示脑血流灌注减低５８例,异常率８２．８５％。ＥＥＧ检查,７０例癫痫发作间期脑电图异常２５例,异常率３５．７１％。ＳＰＥＣＴ脑     

100例矫正性大动脉转位超声心动图诊断

目的 探讨矫正性大动脉转位（ＣＴＧＡ）超声心动图（ＥＣＧ）图像特征,材料和方法 应用ＥＣＧ检查１００例ＣＴＧＡ,男５５例,女４５例,年龄３～４７（平均１０,７）岁,９８例做了心血管造影检查,８０例经手术证实,结果：ＥＣＧ诊断正确９４例,误诊右心室双出口２例,２例诊断大动脉转位,但未明角ＣＴＧＡ,误诊肺动脉闭锁和Ｔａｕｓｓｉｎｇ－Ｂｉｎｇ综合征各１例,结论：应用ＥＣＧ诊断ＣＴＧＡ检查者必须熟练掌握本     

~(99m)Tc-MIBI显像诊断乳腺癌的应用及与其它影像学检查方法的比较研究

９９ｍＴｃ－ＭＩＢＩ显像诊断乳腺癌的应用及与其它影像学检查方法的比较研究任长才①朱锡琪金少津②戴训芦③梁春立①自１９９４年３月～１９９６年９月应用９９ｍＴｃ－甲氧基异丁基异腈（ＭＩＢＩ）对１３５例乳房肿块病人分３组分别进行乳腺显像、Ｂ超及钼靶检查，另...     

完全性左束支传导阻滞伴左室肥厚的心电图诊断之探讨

心电图 (ＥＣＧ)表现为完全性左束支传导阻滞 (ＣＬＢＢＢ)时 ,诊断左室肥厚 (ＬＶＨ)甚为困难。用已被认可的超声技术诊断ＬＶＨ的方法对照观察 ,以探讨ＥＣＧ在ＣＬＢＢＢ时诊断ＬＶＨ简便可行的方法。1　资料和方法1996年 2月～ 2 0 0 0年 2月的住院患者 ,入院 1～ 2天用惠普ｍ1772Ａ型作 12导ＥＣＧ ,符合ＣＬＢＢＢ的 6 0例 :高血压2 5例 ,冠心病 16例 (其中 3例合并肺心病 ) ,扩心病 8例 ,老心病 3例 ,风心病 6例 ,病毒性心肌炎 2例 ;男 32例 ,女 2 8例 ,年龄 45～ 92岁。 6 0例均用惠普ＳＯＮＯＳ10 0 0型作超声检查 ,以左室长轴切面…     

Sonographic detection of kidney infarctions using ultrasound contrast media

Contrast-enhanced CT is currently the gold standard for the diagnosis of kidney infarction. Particularly in patients with renal insufficiency, however, the use of iodine contrast media is limited. Sonographic examination using ultrasound contrast media may be an alternative for these patients. CASE REPORTS: We examined three patients with suspected ischaemic kidney infarction with ultrasound contrast media. Scanning was performed with low mechanical index, and SonoVue was used as by contrast-enhancing agent. In all three patients, kidney infarctions were clearly shown. In two patients, the lesions were confirmed by contrast-enhanced CT, in one no CT was performed because of impaired renal function. CONCLUSION: Kidney infarctions can reliably be detected by contrast-enhanced ultrasound using SonoVue as contrast agent. This is particularly valuable in patients with renal impaired renal function and other contraindications against iodine contrast media.     

The Gandras catheter for uterine artery embolization: The procedure-driven development of a novel medical device

Microbubble contrast media are used to enhance ultrasound images. Because ultrasound is a real‐time investigation, contrast‐enhanced ultrasound offers possibilities for perfusion imaging. This review is conducted to evaluate the safety of contrast‐enhanced ultrasound and its possible role in medical imaging. The safety of diagnostic ultrasound is still an important field of research. The wanted and unwanted effects of ultrasound and microbubble contrast media as well as the effects of ultrasound on these microbubbles are described. Furthermore, some of the possible applications and indications of contrast‐enhanced ultrasound will be discussed. The shared advantages of MRI and ultrasound are the use of non‐ionizing radiation and non‐nephrotoxic contrast media. From this review it can be concluded that, for certain indications, contrast enhanced ultrasound could be a safe alternative to MRI and a valuable addition to medical imaging.     

靶向超声造影的研究进展

靶向超声造影是分子影像学组成的重要部分。通过靶向微泡声学造影剂与细胞表面特异性抗体或配体结合,可以实现在体观察靶组织在组织、细胞及亚细胞水平的病理生理变化。随着对超声造影剂尤其是纳米造影剂研究的深入,靶向超声造影剂在疾病诊断及治疗中的作用越来越受到重视,本文对此作一简要综述。     

早期胃癌临床病理特征与浸润深度的关系

目的探讨早期胃癌临床病理特征与浸润深度的关系,为早期胃癌个体化治疗的选择提供依据。方法回顾性分析2008年1月-2013年1月经外科手术及术后病理证实18例早期胃癌患者的临床、病理资料,对其年龄、性别、有无消化道出血、有无幽门螺杆菌感染及肿瘤部位、大小、内镜分型、分化程度与肿瘤浸润深度的关系进行单因素分析。结果 18例早期胃癌患者中,黏膜下层浸润9例,其中淋巴结转移3例;黏膜内癌9例,均无淋巴结转移。病理类型为未分化型9例,其中癌细胞浸润至黏膜下层7例,伴淋巴结转移3例;分化型9例,仅有2例浸润至黏膜下层,但无淋巴结转移。患者性别、年龄、肿瘤部位、大小及有无幽门螺杆菌感染与浸润深度无关（P〉0.05）,内镜分型为Ⅲ型提示黏膜下浸润可能性大（P〈0.05）。结论内镜下大体分型为Ⅲ型的早期胃癌,因多有黏膜下层的浸润,淋巴结转移率高,不适合内镜下治疗。     

Ultrasound imaging and contrast agents: a safe alternative to MRI?

Microbubble contrast media are used to enhance ultrasound images. Because ultrasound is a real-time investigation, contrast-enhanced ultrasound offers possibilities for perfusion imaging. This review is conducted to evaluate the safety of contrast-enhanced ultrasound and its possible role in medical imaging. The safety of diagnostic ultrasound is still an important field of research. The wanted and unwanted effects of ultrasound and microbubble contrast media as well as the effects of ultrasound on these microbubbles are described. Furthermore, some of the possible applications and indications of contrast-enhanced ultrasound will be discussed. The shared advantages of MRI and ultrasound are the use of non-ionizing radiation and non-nephrotoxic contrast media. From this review it can be concluded that, for certain indications, contrast enhanced ultrasound could be a safe alternative to MRI and a valuable addition to medical imaging.     

Colour Doppler ultrasound in vesicovaginal fistulas

The purpose was to evaluate the feasibility of diagnosing vesicovaginal fistulas by colour Doppler ultrasound with contrast media. Twelve consecutive patients were examined by vaginoscopy, methylene blue test, cystogram and cystoscopy. For ultrasound examination, the bladder was filled with saline. Then diluted contrast media (Levovist) was instilled. Colour Doppler ultrasound revealed a jet phenomenon through the bladder wall toward the vagina, proving the existence of the fistula. Eleven patients had vesicovaginal fistulas, one patient a vesicoureterovaginal fistula. Colour Doppler ultrasound had correct results in 11 of 12 patients (92%). In follow-up examinations of four patients during a prolonged drainage of the bladder, we could correctly demonstrate the closure of one fistula. Colour Doppler ultrasound with contrast media is a new useful diagnostic tool in the evaluation and follow-up of vesicovaginal fistulas. It is less invasive than cystoscopy and needs no radiation exposure. The examination is well tolerated by the patients.     

纳米靶向超声造影剂的研究进展

靶向超声造影是超声分子影像技术的重要部分。随着超声造影技术和生物纳米技术的发展,靶向超声造影剂步入纳米时代。近年来,纳米靶向超声造影剂的制备和在肿瘤诊治中的应用前景备受关注。本文就此进行综述。     

超声联合微泡造影剂介导基因治疗的研究进展

基因治疗将是人类攻克许多难治性疾病的有效方法,超声微泡作为一种新型的基因载体,可以安全、简便、靶向性地将基因转移入特定的组织、细胞。本文阐述了超声联合微泡介导基因治疗的研究进展以及未来的应用前景。     

The reproducibility of intravascular ultrasound imaging in vitro

To determine which factors may affect the image quality when an intravascular ultrasound catheter is used in vivo, the influence of blood, temperature change, and contrast media were evaluated. In addition, to confirm the reproducibility of intravascular ultrasound imaging to measure cross-sectional lumen area, intraobserver and interobserver variability were determined. The findings indicated that ultrasound images in blood are mildly attenuated, that changes from room temperature to body temperature do not have a significant impact on the image quality, that contrast media attenuates the image intensity in a dose-dependent manner, and that the intravascular ultrasound imaging catheter provides a reproducible method for measuring arterial lumen area with excellent intraobserver and interobserver correlation.     

小鼠颊癌颈部淋巴结超声造影的实验研究

目的 探讨局部注射造影剂对移植颊癌原发灶及颈部转移淋巴结增强显像效果.方法 建立小鼠颊癌颈部转移淋巴结动物模型后,经原发灶局部注入自制表面活性剂类超声微泡,以谐波显像方式观察原发灶及颈部淋巴结增强显像效果,同时进行回声强度的比较.结果 造影前,转移淋巴结检出率为61%（17/28）,炎性淋巴结检出率为50%（6/12）;造影后转移淋巴结检出率为82%（23/28）,炎性淋巴结检出率为75%（9/12）.与造影前比较,造影后原发灶和淋巴结的回声强度增大,差异有统计学意义（P〈0.01）结论自制表面活性剂类超声微泡能够经原发灶注入,进入淋巴道,实现显著的淋巴结超声显像增强效果.