Does religiousness explain regional differences in alcohol use in Finland?

AIMS: Because religiousness, a protective factor for alcohol use, is much more prevalent in rural regions, we examined its importance in explaining the differences in adolescent alcohol use found in the rural and the urban regions. In rural Ostrobothnia (hereafter referred to as the rural region), alcohol use is at the lowest level in all of Finland, whereas in Uusimaa, the urban region that surrounds Helsinki (hereafter referred to as the urban region), alcohol use is at the highest level. METHODS: We analysed cross-sectional questionnaire data collected from Finnish adolescents and their mothers, during 1991-1995. RESULTS: Abstinence was more prevalent, drinking less frequent, and religiousness higher in the rural region. In the urban region, there was but a negligible correlation between alcohol use and religiousness, whereas in the rural region, the correlation was clear, especially when abstainers were included. In modelling the relationship between region and adolescent abstinence, we found an interaction between mothers' religiousness and region: high religiousness among mothers was more protective of abstinence in the rural region. CONCLUSIONS: Our results show the importance of religiousness in explaining differences in adolescent alcohol use in regions with different religious traditions, but further studies will be required to explain why mothers' religiousness affects rates of adolescent abstinence differently in the two regions.     

Could the peer group explain school differences in pupil smoking rates? An exploratory study

Schools differ in the proportion of their pupils who smoke. Such differences transcend pupil intake characteristics and relate to the internal life of the school. Although adolescents' smoking behaviour has been associated with that of their peers, little consideration has been given to whether peer structures and processes contribute to school differences in pupil smoking rates. In two relatively deprived Scottish schools, one with a higher and one with a lower rate of pupil smoking, 13 and 15 year-olds were surveyed. Sociometric data and information on pupils' smoking behaviour and views were gathered. Twenty-five single-sex discussion groups were then held with a sub-sample of the 13 year-olds in order to explore in detail their views on smoking, smokers and fellow pupils. Findings showed that in the higher smoking school, pupils were more often in groups, smokers were identified as popular, and attitudes (especially among non-smoking females) were more pro-smoking. In the lower smoking school, by contrast, there were more isolates and dyads, there were no popular smokers and attitudes (especially among non-smoking females) were much less pro-smoking. Thus, evidence suggests peer group structures and related influences could be one explanation for school differences in smoking, and that the popularity of smokers together with the views of non-smoking females may be particularly important in creating such differences.     

Does vitamin d deficiency account for ethnic differences in tuberculosis seasonality in the UK?

Objectives. Notifications of tuberculosis in England and Wales are reported to peak in the summer season. The purpose of this study was to confirm that finding and to determine to what extent patients of Indian Subcontinent (ISC) ethnic origin contributed to the seasonality. The clinical presentation of the disease is presumed to occur some months following reactivation of the endogenous latent focus of tuberculosis infection. There arises the possibility of vitamin D deficiency producing immunological inadequacy at the end of winter and beginning of spring.

Patients and methods. Monthly (or 4‐weekly) aggregated data over 7 years were collected from the three countries of mainland Britain, England, Wales, Scotland and from the city of Birmingham in England. The notifications from Birmingham were divided into those of ISC ethnic origin and ‘whites’. The presence or absence of seasonality was determined by fitting a sinusoidal curve by the technique called ‘cosinor analysis’. In this method amplitude gives a measure of the extent of the seasonal variation.

Results. The summer peak of clinical diagnosis was confirmed in the UK series from England, Wales and Scotland. In England and Wales without Scotland a larger seasonal variation was present. Scotland, with a lower proportion of population of ISC ethnic origin, was examined separately and the results in Scotland alone failed to confirm seasonality. In the data from Birmingham, seasonality was confirmed with a greater amplitude, particularly in those over 60 years of age. The finding was influenced by those of ISC ethnic origin, seasonality not being present in the ‘white’ population.

Conclusion. The results from Birmingham are very striking, but there were almost three times as many patients in the ISC ethnic group as in indigenous ‘white’ patients. A series with larger numbers of ‘white’ patients would be necessary to confirm the absence of seasonality in the ‘white’ population. The discussion reviews the evidence that vitamin D may have an important hormonal role in immunological defence in the prevention of tuberculosis.     

Do sex and ethnic differences in smoking initiation mask similarities in cessation behavior?

OBJECTIVES: This study compared success in smoking cessation by sex, ethnic status, and birth cohort. METHODS: African and European American respondents to the 1996 Current Population Survey (tobacco supplement) and the 1987 National Health Interview Survey (cancer control and cancer epidemiology supplements) constituted the study population. Elapsed time from smoking initiation to cessation was compared via nonparametric tests and survival analysis techniques. RESULTS: Findings showed that success in quitting was independent of ethnic status and sex and that population differences in smoking initiation age (assuming no differences in quitting behavior) could produce statistical associations between sex/ethnicity and smoking cessation. CONCLUSIONS: Population differences in smoking initiation patterns can mask similarities in cessation rates.     

Can social factors explain sex differences in insomnia? Findings from a national survey in Taiwan

STUDY OBJECTIVE: To examine sociological explanations for the higher level of insomnia in women, including social roles and socioeconomic status (SES). DESIGN: Cross sectional survey research SETTING: Taiwanese 2001 "social trend survey" PARTICIPANTS: A nationally representative sample of 39,588 citizens aged 15 years or older living in Taiwan. MAIN RESULTS: On average, women scored 1.25 points higher than men on the insomnia inventory (p<0.001) but after controlling for social roles, the sex discrepancy in insomnia decreased slightly. SES did not, however, explain women's higher levels of insomnia. Subscale analysis showed an association between the role of homemaker and increased night time sleep disturbance and decreased daytime sequelae of poor sleep while higher educational attainment was related only to more severe daytime sequelae. CONCLUSION: The sex discrepancy in insomnia narrowed slightly after taking social role factors into consideration but was not explained by SES. The persistent sex gap in insomnia warrants further investigation.     

Does severity explain differences in hospital length of stay for pneumonia patients?

OBJECTIVES: In the USA, the role of patient severity in determining hospital resource use has been questioned since Medicare adopted prospective hospital payment based on diagnosis-related groups (DRGs). Exactly how to measure severity, however, remains unclear. We examined whether assessments of severity-adjusted hospital lengths of stay (LOS) varied when different measures were used for severity adjustment. METHODS: The complete study sample included 18,016 patients receiving medical treatment for pneumonia at 105 acute care hospitals. We studied 11 severity measures, nine based on patient demographic and diagnosis and procedure code information and two derived from clinical findings from the medical record. For each severity measure, LOS was regressed on patient age, sex, DRG, and severity score. Analyses were performed on trimmed and untrimmed data. Trimming eliminated cases with LOS more than three standard deviations from the mean on a log scale. RESULTS: The trimmed data set contained 17,976 admissions with a mean (S.D.) LOS of 8.9 (6.1) days. Average LOS ranged from 5.0-11.8 days among the 105 hospitals. Using trimmed data, the 11 severity measures produced R-squared values ranging from 0.098-0.169 for explaining LOS for individual patients. Across all severity measures, predicted average hospital LOS varied much less than the observed LOS, with predicted mean hospital LOS ranging from about 8.4-9.8 days. DISCUSSION: No severity measure explained the two-fold differences among hospitals in average LOS. Other patient characteristics, practice patterns, or institutional factors may cause the wide differences across hospitals in LOS.     

Does measurement dependence explain the effects of the Life Skills Training program on smoking outcomes?

BACKGROUND: The Life Skills Training (LST) program is the most prominent school-based smoking prevention program in terms of its consistency in being named on lists of best practices. This study assessed whether the results pertaining to cigarette smoking reported in evaluations of the LST program are measurement dependent. METHODS: Seventeen reports published between 1980 and 2003 that included at least one outcome measure pertaining to cigarette smoking were identified. Data pertaining to the cigarette smoking measures used in the analysis and whether the results showed a statistically significant difference between experimental and control groups at follow-up were extracted from the reports. RESULTS: Fourteen different outcome measures were used across 17 reports. Only three pairs of reports presented the same set of outcomes. Recent reports showed the most consistent set of findings in support of the LST program, but there was little consistency in the outcome measures used in these analyses. CONCLUSIONS: The use of so many smoking outcomes in the LST program evaluations raises concern as to whether the positive program effects reported are measurement dependent.     

Does occupation explain gender and other differences in work-related eye injury hospitalization rates?

OBJECTIVE: We sought to determine whether demographic differences in eye injury rates persist after adjusting for occupational exposure. METHODS: On-duty eye injury hospitalizations were linked to occupation among active-duty US Army personnel. RESULTS: Eye injury rates were higher for white soldiers, men, and for younger soldiers, even after adjusting for occupational group and specific job titles using multivariate models. CONCLUSIONS: This finding contrasts with studies of other injuries, suggesting that occupation does not fully account for variations in eye injury risk. Because protective eye-wear can prevent most serious eye injuries, we hypothesize that differences in protective eye-wear use between men and women may contribute to differences in eye injury rates, although follow-up studies are needed to confirm this. Prevention efforts should consider targeting high-risk demographic groups in addition to high-risk occupations.     

Can sex differences in the psychiatric institution career of alcoholics be identified?

All patients residing in the catchment area ("sector") of the Psychiatric Clinic of Hanover Medical School who had been hospitalized due to alcoholism or drug dependence for the first time in their lifes and had been discharged over the period January 1, 1973, to December 31, 1978, were followed through December 31, 1979. Age was the major determinant of rehospitalization. Patients up to age 40 were rehospitalized more frequently than patients 40 and over. Sex differences in the psychiatric institutional career of alcoholics were small and inconsistent. A relatively large probability of rehospitalization was noted for men and women with high occupational status, failed to reach significance, however. This might be due to confounding by age but together with results of other studies also supports the notion that societal role expectations determine the psychiatric institutional careers of alcoholics.     

Does parental smoking cessation discourage adolescent smoking?

BACKGROUND: We examined the relationship of smoking cessation in parents to smoking and uptake and cessation by their adolescent children. METHODS: We analyzed a cross-sectional sample of 4,502 adolescents, ages 15-17 years, who lived in two-parent households that were interviewed as part of the 1992-1993 Tobacco Supplement of the Current Population Survey, which questioned householders 15 years of age and older about their smoking history. Ever smokers reported smoking at least 100 cigarettes in their lifetime. Former smokers were ever smokers who had quit. RESULTS: Multivariate analyses, adjusted for demographic characteristics of adolescents, as well as father's age, education, and family income, found that adolescents whose parents had quit smoking were almost one-third less likely to be ever smokers than those with a parent who still smoked. Furthermore, adolescent ever smokers whose parents quit smoking were twice as likely to quit as those who had a parent who still smoked. Parental quitting is most effective in reducing initiation if it occurs before the child reaches 9 years of age. CONCLUSION: Encouraging parents to quit may be an effective method for reducing adolescent smoking, through decreased uptake and increased cessation. The earlier parents quit, the less likely their children will become smokers.     

Female resistance to hypoxia: does it explain the sex difference in mortality rates?

There is currently no accepted explanation in the medical literature for the lower female total mortality rate in infancy, childhood and adulthood. We review the pediatric mortality data provided by Centers for Disease Control and Prevention (CDC) and the World Health Organization (WHO) and show that for causes of respiratory infant death that are apparently independent of gender (e.g., suffocation from inhalation of food or other object), there is a consistently one-third lower rate of mortality in the female than in the male. This one-third lower mortality for causes of death with a respiratory terminal event is hypothesized to be due to an X-linked dominant allele that occurs with frequency 1/3. It appears as if a second X chromosome provides the one-third extra probability of protection afforded for an XX female compared with an XY male. It is suggested that the allele's function is unmasked during transient periods of cerebral anoxia, requiring a mechanism for anaerobic oxidation to prevent the death of respiratory control neurons in the brain stem. Examples of the female one-third extra chance of resistance to hypoxia are given for causes of death in infancy, such as infant respiratory distress syndrome (IRDS) and sudden infant death syndrome (SIDS), and for causes of suffocation in childhood and asphyxiation in adulthood. DNA testing of the X chromosome of probands from causes of respiratory death, such as SIDS and IRDS, where there is a one-third lower female than male death rate, is a future direction that can verify the existence of the proposed allele.     

Are there sex and gender differences in acute exposure to chemicals in the same setting?

We have little understanding of the influence that sex and gender may have on exposure to and measurement of occupational chemicals. If men and women are in the same physical environment, whether that be an occupational or an environmental setting, researchers need to question whether their acute exposure, as measured by administered and/or biologically effective dose, is the same. Not doing so may result in incorrect inferences being made about the risks associated with that exposure. Three critical questions arise specifically, do men and women differ in (1) their personal environments (immediate physical environments and personal attributes), (2) their absorption of the substance across the various biological barriers, and (3) the amount of active substance that reaches the target sites? Both contextual (e.g., smoking habits, diet, use of personal care products and jewellery, hobbies, stress, and use of medications) and biological (e.g., endocrine status) factors should be considered in answering these questions. Examples from the literature are provided to show that, depending on the chemical compound, there may be sex and gender differences in exposure to chemicals which can be manifested in sex differences in absorption, distribution, metabolism, storage, and excretion. An argument is developed to support the need to make information available, such as pharmacokinetic modeling studies in both men and women including appropriate age groups representing the spectrum of life stages and reproductive status.     

Social class differences in the accounts of smoking – striving for distinction?

The dominant trend in smoking prevalence in most Western countries is its increasing association with lower socioeconomic positions, making it a major factor behind inequalities in health. This paper focuses on the reasoning behind smoking, as well as on its social significance among middle-class and working-class smokers. The data consist of 55 semi-structured interviews with daily smokers, ex-smokers and occasional smokers from different occupational backgrounds. The analysis revealed considerable differences in the ways of accounting for smoking, relating to the respondents' occupational backgrounds. Contrary to expectations, non-manual workers tended to consider their smoking functional, pleasurable and controlled, whereas the opposite was the case with the manual workers. Despite the high prevalence of smoking in that group, they were least willing to justify or rationalise their behaviour, whereas the agenda of middle-class smokers could be interpreted as the reconciliation of middle-class habitus with a risky, working-class habit.     

Could a tuberculosis epidemic occur in London as it did in New York?

In early 1999, more than 160 senior physicians, public health officials, and nurses met to discuss London's tuberculosis (TB) control program. The program was examined against the public health response of New York City's Bureau of Tuberculosis Control during a 1988 to 1992 epidemic. This article outlines TB epidemiology and control in New York City 10 years ago and in London today to assess whether the kind of epidemic that occurred in New York could occur in London.     

Does the type of treatment supporter influence tuberculosis treatment outcomes in Zimbabwe?

Zimbabwe National Tuberculosis Guidelines advise that direct observation of anti-tuberculosis treatment (DOT) can be provided by a family member/relative as a last resort. In 2011, in Nkayi District, of 763 registered tuberculosis (TB) patients, 59 (8%) received health facility-based DOT, 392 (51%) received DOT from a trained community worker and 306 (40%) from a family member/relative. There were no differences in TB treatment outcomes between the three DOT groups, apart from a higher frequency rate of ‘no reported outcomes’ for those receiving family-based DOT. Family members should be trained to use a suitable DOT support package.