恶性间叶瘤二例

例1 男,63岁.活动后胸闷、气短2个月,弯腰时上腹饱胀及后背痛1个半月于2005年9月12日入院.无吞咽困难及进食梗噎感.体检及实验室检查均无明显异常.     

Gastrointestinal stromal tumor of the small intestine with lung metastasis

Gastrointestinal stromal tumours (GISTs) represent 1% of primary gastrointestinal cancers. These tumors most frequently metastasise to the liver and peritoneum and rarely to the lungs. We report the case of a 79-year-old woman with gastrointestinal stromal tumor of the small intestine and pulmonary metastases. Contrast-enhanced computed tomography (CT) revealed a focal mass centered around the last intestinal loop associated with pulmonary bilateral masses. The diagnosis of gist of the small bowel was confirmed by histopathological and immunohistochemical analyses of bioptic material obtained from CT guided biopsy of pulmonary lesions. To the best of our knowledge, only few cases had been reported in medical literature as This mode of presentation is unusual, with computed tomography (CT) playing a significant role in the diagnosis and management.     

小肠间质瘤的CT诊断价值

胃肠道间质瘤（gastrointestinal stromal tumors,GIST）传统上被诊断为消化道平滑肌（肉）瘤或（恶性）神经鞘瘤。近年的研究发现该肿瘤是一种起源于胃肠道肌壁内Cajal间质细胞的间质性肿瘤。由于小肠间质瘤发病率低,文献报道较少,     

66例小肠恶性肿瘤的临床病理学和免疫组织化学研究

观察66例原发小肠恶性肿瘤的病理组织形态学,并分析临床病理特点,按WHO肿瘤新分类,总结其病理类型,采用SP法,使用6种抗体(Keratin,CEA,S-100,Vimentin,Myoglobin,LCA等)做免疫组织化学染色研究.结果证明:原发小肠恶性肿瘤以小肠癌多见,尤以十二指肠腺癌最常见;恶性淋巴瘤次之,以回肠恶性淋巴瘤常见.     

A shift in the diagnostics of the small intestine tumors

Primary, secondary, benign or malignant tumorous diseases of the small intestine are rare. They are very often diagnosed by accident or as a cause of acute abdomen. This work should answer the question, whether there is a method of making the diagnosis earlier when the disease is limited and easy to cure. METHODOLOGY: A retrospective study comprising 96 patients having undergone surgery for a small intestine tumor in our hospital from 1996 to 2005 is presented. An analysis of first symptoms, diagnostic methods and number of patients admitted during the years was made. In the year 1998 we changed our philosophy in trying to directly detect the small intestine pathology and not making the diagnosis by the exclusion only. Intestinal ultrasound was performed on the Ultramark 3000 HDI device with autofocussable convex 5 MHz and linear 7.5 MHz probes or nowadays ATL 5000 HDI, 7-12 MHz linear probe. No contrast enhancement was used. Abdominal CT engaged Somatom Plus appliance by Siemens, single detector with our conventional abdominal CT protocol. Enteroclysis was done with Micropaque suspension diluted 1:1 with HP-7000 300 ml with its application rate of 75 ml/min followed by HP-7000 solution 2000 ml, application rate of 120 ml/min. RESULTS: We treated surgically 96 patients with the small intestine tumor. A shift in the diagnostic algorithm was noticed in the bowel ultrasound now taking the lead. An enlarged portion of patients diagnosed by means of capsule endoscopy was also seen. An increase of surgically treated patients after 1998 was recorded and the majority of them could be offered an elective laparoscopic surgery in contrast to before 1998 when the majority of them had undergone surgery for an acute abdomen. CONCLUSION: The small bowel ultrasound can be recommended as the first choice method. All patients with even very moderate abdominal symptoms ought to be examined for the small intestine pathology. As a result one can get higher rate of elective surgery, if possible laparoscopic and higher number of R0 resections accompanied by longer survival.     

小肠海绵状血管瘤1例

患者男,68岁。以“下腹痛、腹泻1月”为主诉入院。自诉1月前无诱因出现下腹部间断性隐痛,无放射性疼痛,伴有腹泻,3~5次/日,呈黄色稀糊状便,无粘液脓血性分泌物,排便与腹痛无关,伴纳差,渐消瘦,伴乏力。辅助检查结果:血尿便常规、肿瘤标志物、传染病四项、凝血机制、甲功均未见异常。胃镜提示:慢性非萎缩性胃炎。