MSCT不同层厚的最大密度投影在肺动脉栓塞诊断中的价值

目的：比较16层螺旋CT图像后处理中不同层厚的MIP重组图像对于肺动脉栓子的检出率。方法：对于32例临床拟诊为肺动脉栓塞的患者,采用层厚5mm的胸部增强扫描,利用原始数据分别行0.75mm组,2.mm组,5mm组,10mm组MIP重建。显示清楚的叶、段、亚段肺动脉内有无栓子,并行χ^2检验。结果：CT诊断肺动脉栓塞23例,病变共累及肺动脉72支,对于肺动脉主干及各叶肺动脉栓塞,前4组图像检出率分别为100%、100%、95.2%、90.5%。对于肺段及亚段肺动脉栓塞的检出,0.75mm组及2.mm组（检出率分别为96.1%、90.2%）明显高于5mm组,10mm组（检出率分别为82.9%、60.8%）,0.75mm组及2.0mm组在统计学上没有显著差异（P值为0.433）。2.mm组与5.0mm组、10mm组在统计学上有显著差异。（P值分别为0.004,0.001）。结论：多层螺旋CT,2mm层厚MIP重建图像能明显提高段、亚段肺动脉栓子的显示率,又能减少图像数目,有重要的诊断价值,5.0mm组1、0mm层厚MIP重建图像定位准确,直观明了,为重要的补充,MIP后处理技术为检出肺动脉栓子的最佳技术。     

Detection of pulmonary embolism using 16-slice multidetector-row computed tomography: evaluation of different image reconstruction parameters

OBJECTIVE: To compare different image reconstruction parameters for detecting emboli of the pulmonary arteries according to anatomic levels using 16-slice multidetector-row computed tomography in patients suspected of having an acute pulmonary embolism (PE). METHODS: Sixty-two patients (33 male and 29 female) with a clinically suspected acute PE were included in the present study. Multidetector-row computed tomography scans were performed using 16-mmx0.75-mm collimation. Based on the computed tomography data set, different image reconstruction parameters were used for each patient: axial slice thicknesses (STs) of 0.75, 2, 4, and 6 mm; axial maximum intensity projection (MIP) STs of 4 mm; and coronal STs of 2 and 4 mm. In joint reading fashion, 2 experienced radiologists reviewed examination findings regarding the presence and/or absence of a PE. The reference standard for visualization and detection of PEs was defined using the axial images with a 0.75-mm ST. RESULTS: In 23 of 62 patients, a PE was diagnosed. For main and lobar pulmonary arteries, the sensitivities and specificities were as follows: axial 2-mm images, 1.0/1.0; axial 4-mm images, 1.0/1.0; axial 6-mm images, 0.97/0.99; MIP 4-mm images, 0.95/0.99; coronal 2-mm images, 1.0/1.0; and coronal 4-mm images, 1.0/1.0. Regarding segmental and subsegmental pulmonary arteries, sensitivity and specificity varied: axial 2-mm images, 0.97/1.0; axial 4-mm images, 0.81/0.99; axial 6-mm images, 0.65/0.99; axial MIP 4-mm images, 0.63/0.99; coronal 2-mm images, 0.91/0.99; and coronal 4-mm images, 0.74/0.99. CONCLUSIONS: In detecting segmental and subsegmental PEs, only the axial images with an ST of 2 mm proved to have results comparable with the axial 0.75-mm images. Therefore, thin-slice collimation and ST are mandatory for visualization of segmental and subsegmental PEs in patients suspected of having an acute PE.     

Variability of repeated coronary artery calcium measurements by 1.25-mm- and 2.5-mm-thickness images on prospective electrocardiograph-triggered 64-slice CT

High reproducibility on coronary artery calcium scoring is a key requirement in monitoring the progression of coronary atherosclerosis. The purpose of this prospective study is to assess the reproducibility of 1.25-mm- and 2.5-mm-thickness images on prospective electrocardiograph-triggered 64-slice CT with respect to 2.5-mm-thickness images on spiral overlapping reconstruction. One hundred patients suspected of coronary artery disease were scanned twice repeatedly, both on prospective electrocardiograph-triggered step-and-shoot and retrospective electrocardiograph-gated spiral scans. Using 1.25-mm-thickness collimation, 1.25-mm- and 2.5-mm-thickness image sets on prospective scans and 2.5-mm-thickness image sets with 1.25-mm increment (overlapping) on retrospective scans were obtained. Coronary artery calcium scores, interscan variability and interobserver variability were evaluated. The mean interscan variability in coronary artery calcium measurement on 1.25-mm prospective/2.5-mm prospective/2.5-mm overlapping retrospective scans were Agatston: 10%/18%/12%, volume: 10%/12%/10% and mass: 8%/13%/11% for observer 1 and Agatston: 8%/14%/10%, volume: 7%/9%/10% and mass: 7%/10%/9% for observer 2, respectively. The mean interobserver variability was 5% to 14%. In conclusion, prospective electrocardiograph-triggered 64-slice CT using the 1.25-mm prospective scan shows the lowest variability. The 2.5-mm prospective scan on volume or mass scoring shows variability of around 10%, comparable to 2.5-mm-thickness spiral overlapping reconstruction images.     

Can maximum intensity projection images with multidetector-row computed tomography help to differentiate between the micronodular distribution of focal and diffuse infiltrative lung diseases?

OBJECTIVE: The objective of this study was to evaluate whether maximum intensity projection (MIP) images increased the ability of experienced and resident radiologists to differentiate between the micronodular distribution of focal and diffuse infiltrative lung diseases. METHODS: The cases used in the study were those of 26 patients with focal or diffuse micronodular lung diseases, including 7 cases of sarcoidosis, 6 of miliary tuberculosis, 3 of pulmonary tuberculosis, 3 of chronic bronchitis, 2 of human T-lymphotropic virus type 1-associated bronchoalveolar disorder, 2 of diffuse aspiration bronchiolitis, 1 of atypical mycobacterial infection, and 1 of lymphangitic carcinomatosis. Scans of the entire lung during a single breath hold at 1.25-2.5 mm thickness and a pitch of 6 were performed using a multidetector-row computed tomography (MDCT) apparatus with a 4-row detector. Additional MIP image slabs were produced from the initial axial images on all study patients on a workstation according to a protocol that incorporated a slab thickness of 10 mm, a reconstructed interval of 10 mm, and a window width of -1500 Hounsfield units. The ability of 10 radiologists (5 board-certified radiologists and 5 radiology residents) to interpret contiguous thin-section CT scans and additional MIP images was then studied in an observer performance study. The results of both sets of observer performances were compared using receiver operating characteristic analysis. RESULTS: In the resident observers, the mean area under the receiver operating characteristic curve (Az) value increased significantly from 0.654 without the MIP images to 0.753 with the MIP images (P < 0.01). In the board-certified radiologists, however, the mean Az values remained unchanged at 0.867 without the MIP images and 0.846 with the MIP images. CONCLUSIONS: This study showed that MIP images may help radiologists in training to differentiate between the micronodular distribution of focal and diffuse infiltrative lung diseases.     

Postprocessing technique with MDCT data improves the accuracy of the detection of lung nodules

Purpose The aim of this study was to determine whether postprocessing techniques could improve the accuracy of detecting lung nodules. Materials and methods A total of 154 segmented lung volumes of multidetector-row computed tomography (MDCT) data were the subject of the study. Lung nodules were present in 88 volumes and absent in 66 volumes. We prepared four groups: (1) 7- or 10-mm thick-section axial images; (2) 1-mm thin-section axial images; (3) sliding slab maximum intensity projection (MIP) images with a slab thickness of 15 mm; and (4) sliding slab volume rendering (VR) images with a slab thickness of 15 mm. Sixteen physicians reviewed each group in interactive cine mode. The observers’ performance in the detection of lung nodule was evaluated by receiver operating characteristic (ROC) analysis. Results The observers’ performance of the MIP and VR groups was significantly better than in other two groups. There was no significant difference statistically between the thin and thick groups. Conclusion The detectability of lung nodules is improved with the use of sliding slab MIP and VR using thin-section image data. Thin-section volume data are essential for improving diagnostic accuracy, but observation of thin-section images without utilization of image-processing techniques dose not improve diagnostic accuracy. This article was presented at the 2005 Japan Radiological Society annual meeting     

Pulmonary nodule detection on MDCT images: evaluation of diagnostic performance using thin axial images,maximum intensity projections,and computer-assisted detection

This study aimed at evaluating the diagnostic benefits of maximum intensity projections (MIP) and a commercially available computed-assisted detection system (CAD) for the detection of pulmonary nodules on MDCT as compared with standard 1-mm images on lung cancer screening material. Thirty subjects were randomly selected from our database. Three radiologists independently reviewed three types of images: axial 1-mm images, axial MIP slabs, and CAD system detections. Two independent experienced chest radiologists decided which were true-positive nodules. Two hundred eighty-five nodules ≥1 mm were identified as true-positive by consensus of two independent chest radiologists. The detection rates of the three independent observers with 1-mm axial images were 22 ± 4.8%, 30 ± 5.3%, and 47 ± 2.8%; with MIP: 33 ± 5.4%, 39 ± 5.7%, and 45 ± 5.8%; and with CAD: 35 ± 5.6%, 36 ± 5.6%, and 36 ± 5.6%. There was a reading technique effect on the observers’ sensitivity for nodule detection: sensitivities with MIP were higher than with 1-mm images or CAD for all nodules (F-values = 0.046). For nodules ≥3 mm, readers’ sensitivities were higher with 1-mm images or MIP than with CAD (p < 0.0001). CAD was the most and MIP the less time-consuming technique (p < 0.0001). MIP and CAD reduced the number of overlooked small nodules. As MIP is more sensitive and less time consuming than the CAD we used, we recommend viewing MIP and 1-mm images for the detection of pulmonary nodules. This study was presented at the ECR 2006.     

Spatial domain image filtering in computed tomography: feasibility study in pulmonary embolism

Our objective was to evaluate the clinical feasibility of spatial domain filtering as an alternative to additional image reconstruction using different kernels in chest CT. Spatial domain filtering generates smooth images from sharp images and thus avoids the need for additional reconstructions when two sets of images are desired. Forty adult patients with clinical suspicion of pulmonary embolism were examined utilizing multi-slice CT (Somatom Volume Zoom, Siemens, Germany). Derived from thin collimated source images (100 mAs, collimation 4×1 mm, rotation time 0.5 s, table speed 7 mm/rotation), two sets of images [effective slice thickness (S_eff) 5 mm, reconstruction increment (RI) 5 mm) were generated using lung (Siemens B50) and soft tissue (Siemens B30) kernels. Additionally, B50 images were filtered in the spatial domain, producing images largely equivalent to B30 images. Firstly, diagnostic accuracy was assessed on spatial domain filtered images regarding central, segmental, and subsegmental pulmonary embolism. In a second step, diagnostic accuracy was assessed for the initially reconstructed B30 images. The results were compared with thin axial slices from the same data set, which were considered as the gold standard in this respect (S_eff 1.25 mm, RI 0.8 mm; B30). Initially reconstructed B30 slices and secondary filtered images were rated for subjective image quality, using a five-point scale (1=excellent, 2=good, 3=moderate, 4=poor, 5=non-diagnostic). Finally, quantitative measurements were assessed using the region of interest (ROI) methodology. In 20 patients pulmonary embolism was proven. Five-millimeter images revealed 10 of 10 central emboli, 18 of 19 segmental thrombi, and 18 of 20 emboli on the subsegmental level. Pulmonary embolism was excluded in 18 of 20 subjects, and in 2 patients a false-positive result was obtained in subsegmental arteries. These findings were concordant for reconstructed and filtered images. Quantitative density measurements provided comparable Hounsfield units in this respect. Subjective gradings of image quality, based on soft tissue settings, were 1.30 (±0.61) for reconstructed slices vs 1.35 (±0.62) for filtered images (weighted kappa coefficient 0.6117; 95% confidence intervals 0.3298–0.8935). Spatial domain filtering has proved to be feasible. Compared with conventional soft tissue reconstructions for central, segmental, and subsegmental pulmonary embolism, no significant difference in the diagnostic value of spatial domain filtered images was found. Online modifications of image sharpness and pixel noise in real time leads to a considerable reduction of processing time and cost saving for storage of CT images. Despite different data processing methods, thin effective slice thicknesses and overlapping reconstruction increments are mandatory for detailed CT analysis of pulmonary embolism on the segmental and subsegmental level. Electronic Publication     

Multidetector CT of bronchiectasis: effect of radiation dose on image quality

OBJECTIVE: The purpose of our prospective study was to assess the image quality with respect to the radiation dose incurred by multidetector CT (MDCT) in patients with suspected bronchiectasis. SUBJECTS AND METHODS. Image clusters, composed of nine images, using MDCT (120 kVp, a 2.5-mm collimation, a pitch of 6, and 2.5-mm reconstruction intervals) were obtained at each of two levels-the azygous arch and the right inferior pulmonary vein-at 170, 100, 70, 40, 20, and 10 mA. Independently, two chest radiologists assessed and compared the quality of the images obtained at the six milliamperage exposures. Image quality was graded using a 5-point scale with lung and mediastinal window settings. Radiation doses were measured at each of the six milliamperage settings while scanning the whole lung of a thoracic phantom using MDCT. RESULTS: The mean image quality scores at exposures of 170, 100, 70, 40, 20, 10 mA were as follows: 3.9, 3.7, 3.8, 3.2, 2.5, 1.6 at lung window settings and 4.1, 4.3, 4.0, 3.4, 2.3, 1.3 at mediastinal window settings, respectively. Images obtained at 70 mA were rated significantly better than those obtained at 40 mA or less (p < 0.01). The mean radiation dose at 170, 100, 70, 40, 20, 10 mA was 23.72, 14.39, 10.54, 5.41, 2.74, and 1.50 mGy, respectively. CONCLUSION: With a tube current setting as low as 70 mA, MDCT provides images of acceptable quality and volumetric data sets for the evaluation of bronchiectasis. The trade-off of using MDCT rather than conventional high-resolution CT is that the radiation dose is five times higher with MDCT (10.54 mGy) than with conventional high-resolution CT (2.17 mGy with parameters of 120 kVp, 170 mA, 1-mm collimation, and 10-mm intervals).     

Peripheral pulmonary arteries: identification at multi-slice spiral CT with 3D reconstruction

Our objective was to analyze the peripheral pulmonary arteries using thin-collimation multi-slice spiral CT. Twenty consecutive patients underwent enhanced-spiral multi-slice CT using 1-mm collimation. Two observers analyzed the pulmonary arteries by consensus on a workstation. Each artery was identified on axial and 3D shaded-surface display reconstruction images. Each subsegmental artery was measured at a mediastinal window setting and compared with anatomical classifications. The location and branching of every subsegmental artery was recorded. The number of well-visualized sub-subsegmental arteries at a mediastinal window setting was compared with those visualized at a lung window setting. Of 800 subsegmental arteries, 769 (96%) were correctly visualized and 123 accessory subsegmental arteries were identified using the mediastinal window setting. One thousand ninety-two of 2019 sub-subsegmental arteries (54%) identified using the lung window setting were correctly visualized using the mediastinal window setting. Enhanced multi-slice spiral CT with thin collimation can be used to analyze precisely the subsegmental pulmonary arteries and may identify even more distal pulmonary arteries. Electronic Publication     

Detection of pulmonary nodules by multislice computed tomography: improved detection rate with reduced slice thickness

The purpose of this study was to find out if the use of 1.25-mm collimated thin-slice technique helps to detect more small pulmonary lung nodules than the use of 5 mm. A total of 100 patient examinations that allowed a reconstruction of 1.25-mm slice thickness in addition to the standard of 5-mm slices were included in a prospective study. Acquisition technique included four rows of 1-mm slices. Two sets of contiguous images were reconstructed and compared with 1.25- and 5-mm slice thickness, respectively. Two radiologists performed a film-based analysis of the images. The size and the confidence of the seen nodules were reported. We did not perform a histological verification, according to the normal clinical procedure, although it would be optimal regarding research. Statistical analysis was performed by using longitudinal analysis described by Brunner and Langer [10]. In addition, sensitivity, specificity, negative predictive value and positive predictive value were calculated for each reader using the 1.25-mm sections as the gold standard. As an index for concordance the kappa value was used. A value of p<0.05 was regarded as significant. In 37 patients pulmonary nodules were detected. Twenty-four patients showed more than one nodule; among these, 7 patients had disseminated disease and were excluded from the study. Pulmonary nodules larger than 10 mm in size were equally well depicted with both modalities, whereas lesions smaller than 5 mm in size were significantly better depicted with 1.25 mm (p<0.05). Using 1.25 mm as the gold standard, sensitivity for 5-mm reconstruction interval was 88 and 86% for observers A and B, respectively. No false-positive results were reported for 5-mm sections. Interobserver agreement for nodule detection determined for 1.25-mm reconstruction intervals showed a k value of 0.753, indicating a good agreement, and 0.562 for 5-mm reconstruction intervals, indicating a moderate agreement. Brunner and Langer [10] analysis showed significant differences for slice thickness and no significant difference between the observers. Reduced slice thickness demonstrated an improvement of small nodule detection, confidence levels, and interobserver agreement. Application of thin-slice multidetector-row CT may raise the sensitivity for lung nodule detection, although the higher detection rate of smaller nodules has to be evaluated from a clinical perspective and remains problematic about how the detection of small nodules will effect patient outcome.     

Incremental benefit of maximum-intensity-projection images on observer detection of small pulmonary nodules revealed by multidetector CT

OBJECTIVE: Our purpose was to assess the incremental effect of maximum-intensity-projection (MIP) image processing on the ability of various observers to detect small (<1 cm in diameter) central and peripheral lung nodules revealed by multidetector CT. MATERIALS AND METHODS: We retrospectively identified 25 patients with metastatic disease, each having from two to nine nodules that were 3-9 mm in diameter. Two senior and three junior reviewers interpreted all images on a workstation. The observers first reviewed axial images (3.75-mm collimation, 3-mm reconstruction interval, multidetector acquisition) in cine and sequential fashion and recorded the size, lobe, and central or peripheral (within 1 cm of the edge of lung) location of each nodule. MIP images (10-mm slab, 8-mm interval) were then reviewed, and additional nodules detected were recorded. Final counts were established by consensus. RESULTS: The reviewers found 122 nodules (71 peripheral, 51 central) in the 25 patients. The addition of MIP slabs significantly enhanced reviewer detection of central nodules (p < 0.001) and junior reviewer detection of peripheral nodules (p < 0.001). MIP slabs also reduced the effects of reviewer experience, particularly for peripheral nodules. CONCLUSION: MIP processing reduces the number of overlooked small nodules, particularly in the central lung. Observer nodule detection remains imperfect even when lesions are clearly depicted on images.     

Variability of repeated coronary artery calcium measurements by 16-MDCT with retrospective reconstruction

OBJECTIVE: High reproducibility on coronary calcium scoring is an important factor in monitoring the progression of coronary atherosclerosis. The purposes of this study were, using a 16-MDCT scanner with retrospective reconstruction, to compare the effects of thin-slice images and overlapping image reconstruction on the reproducibility of coronary calcium scoring and to compare 16-MDCT with electron beam CT (EBCT). MATERIALS AND METHODS: Fifty patients underwent two sequential examinations using both EBCT and MDCT. For MDCT, images were reconstructed from the same raw data using the following thicknesses and increments (thickness/increment): 1.25 mm/1.25 mm, 2.5 mm/2.5 mm, and 2.5 mm/1.25 mm. The Agatston, volume, and mass scores were calculated on four pairs of image sets. Statistical analysis was performed to determine significant differences in interscan variability among image acquisition protocols and among measurement algorithms. RESULTS: Overlapping reconstructed images (thickness/increment, 2.5 mm/1.25 mm) obtained on a 16-MDCT scanner showed the lowest variability (mean, 13%; median, 10%) when compared with the Agatston score. CONCLUSION: The use of 16-MDCT with overlapping reconstruction by retrospective reconstruction, yielding low variability of coronary artery calcium measurement on two sequential scans, has an advantage over EBCT in monitoring the progression of atherosclerosis.     

Pulmonary MR angiography at 1.0 T: early results with k-space segmented and post-contrast TurboFLASH two-dimensional time-of-flight sequences

Purpose: To evaluate the combined performance of two time-of-flight methods in imaging the pulmonary arteries. Materials and methods: This study was prospectively conducted in 28 patients suspected for pulmonary embolism (PE). Sixteen patients were free of pulmonary vascular disease, and 12 had pulmonary vascular disease as demonstrated by pulmonary angiography. To reduce artifacts caused by cardiac and respiratory motion, MR images were acquired in all subjects using bi-dimensional (2D), gradientrecalled echo (GRE), breath-hold techniques. Sagittal thin (6-mm) sections obtained with ECG gating, k-space segmentation and incremented flip-angles (TONE), and coronal thick (15-mm) sections obtained after a unique injection of Gadolinium chelate were used. Results: High quality images were obtained in all 16 (100%) subjects free of pulmonary disease with both techniques, and in 10 and 12 (87% and 100%) patients suspected for pulmonary artery disease with sagittal and coronal Gd-enhanced MRA, respectively. In patients free of pulmonary disease, TONE images exhibited distal pulmonary arteries with 2.1 subsegmental divisions on average, whereas Gd-enhanced TurboFLASH images were the most accurate to identify proximal pulmonary arteries within the mediastinum, even if only 0.8 subsegmental divisions were seen on average. A correct diagnosis of pulmonary embolism was obtained in all cases but one, with use of both MRA techniques, with an overall accuracy of 86%. Conclusion: The association of segmented sagittal GRE images and coronal first-pass Gd-enhanced GRE images can provide information upon normal and diseased pulmonary arteries within the mediastinum until subsegmental pulmonary branches, even in patients with short-breathing. Further studies of patients with various pulmonary artery diseases will confirm whether this technique makes pulmonary MRA feasible in clinical routine situations.     

Quantitative parameters of image quality in 64-slice computed tomography angiography of the coronary arteries

We explored quantitative parameters of image quality in consecutive patients undergoing 64-slice multi-detector computed tomography (MDCT) coronary angiography for clinical reasons. Forty-two patients (36 men, mean age 61 +/- 11 years, mean heart rate 63 +/- 10 bpm) underwent contrast-enhanced MDCT coronary angiography with a 64-slice scanner (Siemens Sensation 64, 64 mm x 0.6 mm collimation, 330 ms tube rotation, 850 mAs, 120 kV). Two independent observers measured the overall visualized vessel length and the length of the coronary arteries visualized without motion artifacts in curved multiplanar reformatted images. Contrast-to-noise ratio was measured in the proximal and distal segments of the coronary arteries. The mean length of visualized coronary arteries was: left main 12 +/- 6 mm, left anterior descending 149 +/- 25 mm, left circumflex 89 +/- 30 mm, and right coronary artery 161 +/- 38 mm. On average, 97 +/- 5% of the total visualized vessel length was depicted without motion artifacts (left main 100 +/- 0%, left anterior descending 97 +/- 6%, left circumflex 98 +/- 5%, and right coronary artery 95 +/- 6%). In 27 patients with a heart rate < or = 65 bpm, 98 +/- 4% of the overall visualized vessel length was imaged without motion artifacts, whereas 96+/-6% of the overall visualized vessel length was imaged without motion artifacts in 15 patients with a heart rate > 65 bpm (p < 0.001). The mean contrast-to-noise ratio in all measured coronary arteries was 14.6 +/- 4.7 (proximal coronary segments: range 15.1 +/- 4.4 to 16.1 +/- 5.0, distal coronary segments: range 11.4 +/- 4.2 to 15.9 +/- 4.9). In conclusion, 64-slice MDCT permits reliable visualization of the coronary arteries with minimal motion artifacts and high CNR in consecutive patients referred for non-invasive MDCT coronary angiography. Low heart rate is an important prerequisite for excellent image quality.     

Detection of pulmonary nodules at spiral CT: comparison of maximum intensity projection sliding slabs and single-image reporting

The aim of this study was to compare numbers of pulmonary nodules detected with maximum intensity projections using a slab thickness of 15 mm (MIP 15) and 30 mm (MIP 30) with single image (SI) presentation of chest CT scans. Two readers reviewed MIP 15, MIP 30, and SI presentations of 10-mm (n = 8) and 5-mm collimation (n = 10) helical CT scans and recorded size, location, and diagnostic confidence (definite, probable) of pulmonary nodules. Readers 1 and 2 recorded more nodules with MIP 15 than with SI: 10-mm collimation, 77/64 and 60/56; 5-mm collimation, 64/60 and 40/36; and more "definite" nodules (10-mm collimation: 68/57 and 51/42; 5-mm collimation: 43/36 and 34/30). MIP 15 also detected more nodules than MIP 30 at 10-mm collimation: 77/72 and 60/50; with no major differences at 5-mm collimation: 64/66 and 40/38; and more "definite" nodules (10-mm collimation: 68/58 and 51/36; 5-mm collimation: 43/39 and 34/29). There were only minor differences between SI and MIP 30. Reading time and image number per study were reduced with MIP presentations by a factor of 1.4-5.3. There were no significant differences in the number of nodules detected with SI, MIP 15, and MIP 30, but MIP presentation reduced reporting time and filming cost when compared with SI reporting. For detection of nodules MIP 15 was slightly superior to MIP 30.     

多层螺旋CT对周围肺动脉显示能力的研究

目的比较多层螺旋CT肺动脉造影不同层厚重建对周围肺动脉的显示能力. 资料与方法 21例无肺部疾患和血栓病史的患者行CT肺动脉造影检查,均用0.75 mm准直扫描,分别用0.75 mm/0.5 mm（层厚/层间距）（A组）、1.0 mm/0.6 mm（B组）、1.5 mm/1.0 mm（C组）重建,记录每例患者3种不同重建层厚对段肺动脉、亚段肺动脉、5级和6级肺动脉的显示情况及血管不能显示的原因. 结果 3组人均肺段动脉的显示率均为96.45%（19.29/20）;人均亚段动脉显示率分别为94.42%、93.44%、91.13%,3组间均无显著性差异;A、B、C组对第5级肺动脉的人均显示率分别为80.44%、73.47%、59.02%,A组与C组有显著性差异（P＜0.01）,B组与C组间有显著性差异（P＜0.05）;6级肺动脉3组人均显示率分别为33.75%、31.69%、23.56%,A组与C组有显著性差异（P＜0.01）.段肺动脉不能分析的主要原因是解剖变异（53.33%）和心脏搏动伪影（40%）;A、B组亚段肺动脉不能分析的主要原因是解剖变异和心脏搏动伪影,C组的主要原因是部分容积效应（43.84%）与A组比较有显著性差异（10.87%）（P=0.015）;3组对5级和6级肺动脉不能分析的主要原因均为部分容积效应. 结论多层螺旋CT肺动脉造影0.75 mm、1.0 mm、1.5 mm重建层厚对段肺动脉和亚段肺动脉均有很好的显示率,A、B组对5级肺动脉的显示率也较好.影响亚段肺动脉显示的主要原因是解剖变异和心脏搏动伪影.1.0 mm重建层厚可满足肺动脉的观察和图像处理的需要.     

Pulmonary embolism: optimization of small pulmonary artery visualization at multi-detector row CT

PURPOSE: To compare the frequency of well-visualized pulmonary arteries according to anatomic level by using different collimation with single- and multi-detector row computed tomography (CT) in patients suspected of having acute pulmonary embolism. MATERIALS AND METHODS: Sixty patients were examined with one of three techniques (20 patients each). Group 1 was examined with single-detector row CT with 3-mm collimation and 1.3-1.6 pitch; groups 2 and 3, with multi-detector row CT with 2.5- and 1.25-mm collimation, respectively. Three thoracic radiologists independently reviewed examination findings to determine if each main, lobar, segmental, and subsegmental artery was well visualized for presence of pulmonary embolism. chi2 tests were performed. For well-visualized vessels, the presence and/or absence of pulmonary embolism was recorded and kappa statistic was determined. RESULTS: Reader 1 scored 95% (114 of 120), 96% (115 of 120), and 99% (119 of 120) of lobar arteries (P >.05); 76% (304 of 400), 86% (346 of 400), and 91% (363 of 400) of segmental arteries (P <.001); and 37% (300 of 800), 56% (448 of 800), and 76% (608 of 800) of subsegmental arteries as well visualized (P <.001) using techniques 1, 2, and 3, respectively. Reader 2 scored 97% (116 of 120), 95% (114 of 120), and 99% (119 of 120) of lobar arteries (P >.05); 77% (308 of 400), 87% (349 of 400), and 93% (371 of 400) of segmental arteries (P <.001); and 39% (310 of 800), 53% (422 of 800), and 78% (621 of 800) of subsegmental arteries (P <.001) as well visualized using techniques 1, 2, and 3, respectively. Reader 3 scored 86% (103 of 120), 82% (98 of 120), and 91% (109 of 120) of lobar arteries (P >.05); 63% (252 of 400), 70% (280 of 400), and 85% (339 of 400) of segmental arteries (P <.001); and 39% (310 of 800), 56% (451 of 800), and 71% (572 of 800) of subsegmental arteries (P <.001) as well visualized using techniques 1, 2, and 3, respectively. Sixteen patients had pulmonary embolism. Interobserver agreement for detection of pulmonary embolism was significantly better for segmental and subsegmental arteries for all readers with technique 3 (segmental, kappa = 0.79-0.80; subsegmental, kappa = 0.71-0.76) than that with technique 1 (segmental, kappa = 0.47-0.75; subsegmental, kappa = 0.28-0.54). CONCLUSION: Multi-detector row CT at 1.25-mm collimation significantly improves visualization of segmental and subsegmental arteries and interobserver agreement in detection of pulmonary embolism.     

急性肺动脉栓塞CTA检查技术和图像后处理方法的探讨

目的 通过研究16层螺旋CT血管造影的检查技术和图像后处理方法,以期提高基层医院对急性肺动脉栓塞(PE)的诊断准确率.方法 收集临床高度怀疑急性PE患者30例,随机分为两组各15例,采用相同检查流程,在不同扫描条件下进行CT肺动脉血管成像,原始图像在ADW4.3图像工作站中采用MPR、MIP及VR方法进行后处理.观察不同扫描条件和不同后处理技术对PE诊断正确率的影响.结果 ①对比剂浓度300mgI/ml、350或370mgI/ml均可,剂量80～90ml为宜,注射速率3～3.5ml/s即可;②延迟扫描时间17～20s,肺动脉及分支对比剂充盈良好;③吸氧及呼吸训练有助于减少伪影;④扫描范围从肺底至肺尖,足先进,对减少膈肌运动引起的呼吸伪影有好处;⑤肺叶及以上动脉内栓子在MPR、MIP和VR显示率相仿,但MPR有助于显示肺段及以下动脉内栓子.结论 16层螺旋CT采用合适的扫描技术和图像后处理方法,能有效提高PE患者的诊断正确率,在基层医院具有推广价值.     

40层螺旋CT在肺动脉栓塞诊断中的应用价值

目的:探讨40层螺旋CT在肺动脉栓塞中的应用价值.方法:使用40层螺旋CT扫描机(Siemens Defination AS 40)对临床初步诊断肺动脉栓塞的38例患者进行研究.采用层厚5 mm行胸部增强扫描.利用3D后处理工作站进行重建为0.75 mm的轴面及多平面重建(MPR).比较层厚5 mm和1mm的轴面图像及MPR图像.结果:CT诊断肺动脉栓塞31例.病变共累计肺动脉260支.对于主肺动脉及肺叶动脉栓塞,3种图像检出结果一致.但对于肺段及亚段肺动脉栓塞的显示,层厚0.75 mm优于5 mm,差异有显著性意义(P<0.01),0.75 mm的MPR与轴面图像间差异无显著性意义(P＞0.05).结论:40层螺旋CT在肺动脉栓塞诊断中具有无创、快速、敏感性高的优点,应当作为肺动脉栓塞的首选检查方法.     

16层螺旋CT肺血管造影在肺动脉栓塞诊断中的应用

目的　研究 16层螺旋CT肺血管造影在肺动脉栓塞诊断中的应用价值。方法　使用 16层螺旋CT扫描机 (SiemensSensation 16 )对临床拟诊肺栓塞的 4 9例患者进行前瞻性研究。采用层厚 3mm行胸部增强扫描。利用原始数据行层厚 1mm的轴面及多平面重建 (MPR)。比较层厚 3mm、1mm的轴面图像及MPR图像。结果　CT诊断肺栓塞 4 2例。病变共累及肺动脉 35 2支。对于主肺动脉及肺叶动脉栓塞 ,三种图像检出结果一致。但对于肺段及亚段动脉栓塞 ,层厚 1mm较 3mm显示率高 ,差异有显著意义 (P <0 0 1) ,1mm的MPR较轴面图像显示率高 ,但差异无显著性意义 (P >0 0 5 )。结论　 16层螺旋CT肺血管造影无创、快速、敏感性高 ,应当作为肺栓塞的首选检查方法。