泌尿系统结核并前列腺鳞状细胞癌1例报告

<正>前列腺鳞状细胞癌临床罕见,可继发于慢性刺激,早期常缺乏特异性症状,内分泌治疗不敏感,预后差。本院于2012年11月收治1例,报告如下。1病例资料患者男,76岁。因"尿频、尿急、排尿不畅10年余,加重2周"于2012年11月入院。患者30年前因反复尿频、尿急就诊,确诊泌尿系统结核,行左肾输尿管切除,术后抗痨治疗,结核病偶有反复。近10年来尿路刺激症状明显,2010年3月门诊查前列腺特异性抗原     

原发性前列腺鳞癌1例报告并文献复习

目的:提高对原发性前列腺鳞癌的病因及诊治的认识。方法:回顾性分析1例64岁男性原发性前列腺鳞癌患者临床资料:经病理检查诊断为原发性前列腺鳞癌,行手术治疗后辅以放疗,并复习相关文献,探讨本病的病因、诊治及预后。结果:患者术后随访11个月,仍存活。结论:原发性前列腺鳞癌临床罕见,恶性程度高,肿瘤进展快,预后差;对内分泌治疗无效,早期手术治疗并辅以放化疗效果明显。     

前列腺基底细胞癌1例报告并文献复习

<正>前列腺基底细胞癌临床罕见,治疗及预后报道不一,尚处于文献积累中。我院2008年收治1例,现结合文献复习报告如下。1临床资料患者老年男性,85岁,因尿频、排尿不尽感3年     

前列腺小细胞癌2例病例报告并文献复习

目的 探讨前列腺小细胞癌的临床、病理特点及治疗方法.方法 回顾性分析2例前列腺小细胞癌病例资料并进行文献复习.结果 2例均行前列腺穿刺活检病理提示前列腺小细胞癌,1例全身多发性骨转移,1年后死于多脏器功能衰竭;另1例放弃治疗并自动出院,失访.结论 前列腺小细胞癌临床罕见,恶性程度高,预后差,确诊主要依靠病理诊断.早期应根治性切除+化疗;晚期则无满意的治疗方法,主要是化疗.     

原发性前列腺鳞状细胞癌1例报告

<正>前列腺鳞状细胞癌是罕见的前列腺肿瘤。我科在2010年1月诊断1例。现结合文献复习,对其临床资料、病理学诊断及免疫表型报道如下。1病例资料患者男性,57岁,因进行性排尿困难、尿排不尽1月余,加重伴便秘1周入院。专科检查前列腺指诊:前列腺增大,约两横指,质韧,右侧叶可及质硬结节,约2cm。质韧,无压痛     

肾鳞状细胞癌合并膀胱鳞状细胞癌2例报告并文献复习

目的 提高对肾鳞状细胞癌合并膀胱鳞状细胞癌的认识并行文献复习.方法 总结我院收治的2例肾鳞状细胞癌合并膀胱鳞状细胞癌的患者,结合文献就其临床表现、转移途径、诊断及治疗原则进行讨论.结果 2例患者行肾盂癌根治术、膀胱癌根治术加乙状结肠代膀胱术,随访至今,1例健在,1例失访.结论 肾鳞状细胞癌合并膀胱鳞状细胞癌临床罕见,早...     

前列腺小细胞癌二例报告并文献复习

目的探讨前列腺小细胞癌的临床、病理特征及治疗方法。方法总结2例前列腺小细胞癌患者的临床资料并进行文献复习。例1,50岁,因排尿困难伴会阴部疼痛3个月入院。直肠指检前列腺Ⅲ度(5．0 cm×6．0 cm)增生,质硬,表面欠光滑。血清PSA 0．31 ng／ml,fPSA 0．09ng／ml。B超示低回声块,CT示前列腺密度不均。经直肠穿刺活检示前列腺癌,行前列腺癌根治术。例2,82岁,因排尿困难伴间歇性血尿4个月入院。直肠指检前列腺Ⅱ度(4．0 cm×5．0 cm)增生,质硬伴多发性结节,表面欠光滑。血清PSA 2．61 ng／ml,fPSA 0．05ng／ml。B超示低回声块,CT示前列腺密度不均,精囊及膀胱颈部受侵犯。经直肠穿刺活检示前列腺小细胞癌,行双睾切除术加TURP。结果2例术后病理均诊断为前列腺小细胞癌。肿瘤呈弥漫性片巢状结构,伴大片凝固性坏死,核小、燕麦状或圆形、染色深、核仁不明显、胞质少,类似肺小细胞癌。精囊及膀胱颈部均有肿瘤细胞浸润。免疫组化染色检查:LCA、L-26、34βE12(-),PSA、AE1／AE3、AR(+),CA、S-100(±)。例1术后1个月死于广泛肺转移,例2术后3个月发现后腹膜转移,仍在随访中。结论前列腺小细胞癌少见,确诊依靠临床及病理表现。对早期前列腺小细胞癌,根治性前列腺癌切除术加激素及化疗是可行的,晚期患者则无较满意的治疗方法,且预后差。     

前列腺小细胞癌3例报告并文献复习

目的 探讨前列腺小细胞癌的临床、病理特征及治疗方法.方法 回顾性分析3例前列腺小细胞癌患者的临床资料并复习文献.结果 2例术后病理诊断为前列腺小细胞癌,1例经直肠穿刺活检示前列腺小细胞癌,切片见肿瘤呈弥漫性片、巢状结构,伴大片凝固性坏死.核小、燕麦状或圆形、染色深、核仁不明显、胞质少,类似肺小细胞癌.例1行免疫组化染色检查:LCA、L-26、34 B E12、P504s(-),PSA、AE1/AE3、AR(+),CA、S.100(±).例l术后3个月死于全身广泛转移,例2术后13个月死于肺转移,例3术后5个月,仍在随访中.结论 前列腺小细胞癌是一种少见的高度恶性的肿瘤,确诊主要依靠病理诊断,早期即可发生转移,预后较差.目前尚无较满意的治疗方法.     

前列腺小细胞癌1例报告并文献复习

<正>前列腺小细胞癌(small cell carcinoma of the prostate,SCCP)是一种临床比较少见的恶性肿瘤,分化差,恶性程度高,生长快速,极易发生浸润和转移,预后很差。前列腺小细胞癌发病率很低,在所有前列腺癌中所占比例1%[1]。1977年Wenk等[2]首次报道了前列腺小细胞癌,之后国内外陆续有个案报道,但总体例数不多,且多数病例为前列腺小细胞癌混合前列腺腺癌,少见完全性前列腺小细胞癌     

前列腺小细胞癌诊治特点分析(附2例报告并文献复习)

小细胞癌多发生在肺部,肺外较罕见,原发于前列腺的小细胞癌罕见,肿瘤分化低、易转移,无有效治疗手段,预后极差[1].2006年至2010年我院收治2例,现报道如下.     

Squamous cell carcinoma of the prostate: report of 2 cases and review of the literature.

Two cases of squamous cell carcinoma of the prostate are reported and criteria for diagnosis are suggested. Squamous cancer, which accounts for 0.5 to 1% of prostatic malignancies, differs from the common adenocarcinoma of the prostate in certain clinical features. It also appears to have a worse prognosis and to be unresponsive to the usual therapies for prostatic cancer, perhaps because of a different cell of origin.     

Squamous cell carcinoma in chronic ulcerative lesions: a case report and literature review

A case report and literature review are presented involving a fatal case of squamous cell carcinoma of the lower extremity. The unique aspects of this patient include the young age at presentation (35 years old), and the association with both a burn scar (Marjolin's) ulcer and a draining osteomyelitis fistulus tract. Epidemiologic data for Marjolin's ulcers as well as squamous cell carcinoma associated with draining sinus tracts of osteomyelitis are reviewed, in addition to the recommended management of such patients. The case presented is a reminder of the need to maintain a high index of suspicion for malignant transformation within ulcerative lesions.     

Squamous cell carcinoma of renal pelvis: a case report and review of the Japanese literature

Squamous cell carcinoma of renal pelvis is relatively rare and its prognosis is very poor. A 72-year-old man was introduced to our institute because of macroscopic hematuria. He had no history of urolithiasis or urinary tract infection. Excretory urography showed a nonfunctioning right kidney. Cytologic examination of urine was positive for malignant cell from squamous cell carcinoma. Preoperative diagnosis was made as right renal pelvic tumor, but it appeared to be renal tumor on the roentgenogram. Right radical nephrectomy and transurethral ureterectomy was performed. Radiation therapy was done after operation. Pathological diagnosis was squamous cell carcinoma of renal pelvis extensively infiltrating to the renal parenchyma. The patient is alive with no recurrence or metastasis for eight months after operation. Statistical analysis was made on 136 cases of squamous cell carcinoma of renal pelvis reported in the Japanese literature including our case, and this disease is also briefly reviewed.     

Squamous cell carcinoma of the gastric stump. A case report and review of the literature

Adenosquamous and pure squamous cell carcinomas of the stomach are very rare. This report is apparently the first published case of pure squamous cell carcinoma of the gastric stump. It occurred in a 67-year-old patient 37 years after Billroth II resection. This case satisfied the criteria established in the literature for the diagnosis of gastric squamous cell carcinoma. A diagnosis of adenosquamous carcinoma was excluded by extensive histologic investigation of a large number of tissue samples--a total 122 sections from 25 blocks--that revealed neither glandular structures nor mucin. The tumor stroma contained an unusually large number of eosinophils. Immunohistochemically, the tumor cells reacted with a monoclonal antibody against keratin (KL1), but not with antibodies against neuroendocrine or endothelial markers, or alpha 1-antichymotrypsin. The tumor may possibly originate from ectopic squamous epithelium, squamous metaplasia of the gastric mucosa, or an undifferentiated mucosal stem cell. However, we excluded an endothelial origin (which has been proposed by other authors) on the basis of immunohistochemical findings.     

Renal cell carcinoma: case report and literature review

Renal cell carcinoma arising from epithelial cells of the renal tubule is a highly aggressive and malignant tumor in all ages. Less than 2% of cases occur in childhood, relatively in older age group. Only a few pediatric series have been presented in the English literature. Tumor is presented with characteristic findings of flank pain, gross hematuria, and palpable mass. Although one half of the patients have metastasis at the time of diagnosis, most cases are currently being incidentally detected using improved imaging techniques. The overall prognosis in children appears to be similar to that in adults. Tumor stage and complete surgical resection have been reported as the most meaningful prognostic factors for the outcome. The incidence of metastatic disease is same as in adults. The effect of chemotherapy and immunotherapy, either preoperatively or postoperatively, is unclear. Cure is the most likely consequence in localized and completely resected tumors. Here, we present an 8-year-old boy with renal cell carcinoma demonstrating only hematuria without any pathological physical examination findings. The mass was described by abdominal ultrasonography and computed tomography in the left kidney. After the left nephroureterectomy, the patient was given no therapy.     

Hypercalcemia in carcinoma of the prostate: case report and review of the literature

Hypercalcemia developed in a man with recurrent adenocarcinoma of the prostate. Serum calcium became normal soon after bilateral orchiectomy and the patient was free of disease 18 months later. The absence of radiographically detectable bone metastases in this patient suggested a humoral mechanism for the hypercalcemia. Orchiectomy may be an effective treatment for hypercalcemia complicating prostatic carcinoma.