Invasive pituitary adenoma mimicking meningioma

It is not always possible to differentiate invasive pituitary adenoma from the other parasellar tumours. A case of an invasive pituitary adenoma mimicking a meningioma is reported. The importance of a correct pre-operative diagnosis is emphasized.     

Rhinophycomycosis

A case of rhinoentomophthoromycosis in a boy of 11 years is reported for its rarity in India. The various difficulties in its diagnosis and its response to treatment are discussed. Although the culture may be negative in these cases, the unmistakable histopathological picture is always confirmatory.     

Calcifications in Mutinous Adenocarcinoma of the Stomach: A Case Report

Thirty-nine cases of calcification of the gastric carcinomahave been reported in world medical literature. Calcificationsare always punctate in appearance, permitting a confident diagnosisof mucinous adenocarcinoma. An additional case of a sixty-nine-year-oldfemale with calcification in musinous adenocarcinoma, is presentedhere with emphasis on the usefulness of computed tomography.     

Pericardial breast cancer metastasis 25 years after mastectomy

Pericardial effusion in a patient with a history of cancer should always prompt a hypothesis of malignant involvement. We report the case of a 66-year-old white woman presenting with pericardial effusion 25 years after a mastectomy for ductal breast carcinoma. This is one of the cases with the latest recurrence ever reported.     

Thoracoscopic surgery for pulmonary oncocytoma,an uncommon neoplasm

Oncocytoma is an uncommon neoplasm with a characteristic histologic feature of abundant eosinophilic granular cytoplasm. It almost always occurs in kidney, thyroid, or salivary gland. Pulmonary oncocytoma is a rare pulmonary neoplasm, with fewer than 10 cases reported so far in the available English literature. We encountered one such case that was successfully managed by thoracoscopic lobectomy.     

Free Intra-Peritoneal Gas — An Unusual Aetiology

The presence of free gas under one or both hemidiaphragms on an erect chest x-ray is most frequently the result of recent abdominal surgery or, in the absence of such surgery, is almost always indicative of a perforated abdominal viscus. A case is reported of a patient in whom pneumoperitoneum was discovered incidently on a chest x-ray following extensive pelvic manipulation for acute inversion of the uterus.     

Calvarial Doughnut Lesions with Osteoporosis,Multiple Fractures,Dentinogenesis Imperfecta and Tumorous Changes in the Jaws. (Report of a Case)

A case of calvarial doughnut lesions with osteoporosis, multiple fractures, dentinogenesis imperfecta and tumorous changes in the jaws in a 21 year old man observed since infancy is reported. This is the youngest and most severe case of calvarial doughnut lesions ever described. In the opinion of the authors calvarial doughnut lesions are not always benign but may be an expression of a generalised, severe bone disease.     

Thymoma with chronic diarrhea

Thymoma associated with hypogammaglobulinemia and profound susceptibility to recurrent and serious infections was first reported by Good in 1954, after whom it was named as Good's syndrome. Chronic diarrhea associated with thymoma is almost always seen in patients with hypogammaglobulinemia. However, chronic diarrhea in a setting of normal gammaglobulins have been rarely reported. We hereby report two cases of thymoma with normal immune functions, presenting with chronic diarrhea as the only symptom of thymic malignancy. We discussed the etiopathogenic relation between thymic pathology and diarrhea and review the cases of thymoma associated with chronic diarrhea in the English literature.     

Multiple sclerosis presented with acute onset facial palsy

Multiple sclerosis is an uncommon disease in India. Facial nerve palsy is an uncommon presentation of multiple sclerosis. Two cases of acute onset infranuclear facial palsy are reported. The ‘possible’ aetiology was multiple sclerosis. Acute onset facial palsy, especially in young adults may not always be ‘idiopathic’.     

Successful rectal cancer local recurrence radiofrequency ablation

Local rectal cancer recurrences represent a great challenge, as surgical re-excisions or re-irradiation procedures are not always feasible. Moreover, scar or local recurrence is hard to elucidate with conventional diagnosis techniques. Emerging diagnostic and therapeutic procedures may be useful in this setting. A local rectal cancer recurrence radiofrequency ablation is reported. PET scan confirmed the recurrence, defined the target volume and assessed the success of the local therapy.     

Bronchopneumonia disguising lung metastases of a painless central chondrosarcoma of pubis

Chondrosarcoma is a generally locally malignant chondroid-forming bone tumor with a low potential for distant metastases. A small and completely painless central chondrosarcoma of pubis metastasizing to the lungs in a 63-year-old woman with bronchopneumonia is reported. Here we emphasize the mimicry and low growth of the chondrosarcoma and the easiness with which the diagnosis in completely asymptomatic patients can be missed. Although painless chondrosarcoma metastasizing to lung is rather rare, this tumor should be always included in the differential diagnosis of malignancies in this age category.     

大块骨质溶解症一例报告并文献复习

大块骨质溶解症又称Gorham-Stout综合征,是一种罕见的以大块骨质溶解为特征的骨损害。诊断主要依据影象学和病理组织学检查。组织切片检查可见骨质内脉管肿瘤样改变。报道1例以右股骨病理性骨折收入院的大块骨质溶解症患者,临床随访3年。该患者采用双磷酸盐类药物治疗,临床症状缓解。结合文献对诊断标准进行讨论。     

前哨淋巴结识别应用于早期宫颈癌诊治的研究进展

淋巴结转移是影响早期宫颈癌患者预后的重要因素,常规术前检查往往不能发现淋巴结转移.应用前哨淋巴结活检技术,可对淋巴结转移情况做出较好预测.目前文献报道的前哨淋巴结识别方法较多,主要包括:染料示踪法、核素示踪法及联合示踪法.     

Breast cancer risk assessment and management in primary care: provider attitudes, practices, and barriers

Background: We surveyed primary care providers to evaluate breast cancer risk assessment and management practices. Methods: Primary care providers included staff (attendings, fellows, nurse practitioners) and residents practicing ≥1 session/week in an outpatient general medicine practice or community practices. Of 201 eligible providers, 107 (53%) completed a self-administered questionnaire ascertaining attitudes, perceived barriers, and clinical practices related to assessing and managing breast cancer risk. Results: Of providers, 96% mostly or definitely agreed that assessing breast cancer risk was a primary care provider's responsibility. In assessing risk, most providers reported usually or always asking about family history (71%), but fewer usually or always ask about parity (48%), biopsies (40%), or menarche (35%), and most never calculate Gail scores (76%). In managing women at high risk for breast cancer, many providers reported usually or always communicating increased risk to patients (58%) and tailoring screening based on risk (53%); however fewer providers usually or always discuss chemoprevention (13%) or genetic testing (16%) or refer to specialists (35%). Addressing more immediate issues (25%) and lacking confidence in knowledge of risk and risk assessment (20%) were the most commonly reported barriers to assessing risk (n = 83). Conclusion: Primary care providers generally assess breast cancer risk primarily using family history, potentially missing women at increased risk based on other criteria. In addition, although providers tailor screening and refer women at high risk to specialists, they infrequently discuss chemoprevention or genetic testing. Addressing perceived barriers to assessing risk may improve care.     

Hodgkin's disease and granulomatous angiitis of the central nervous system.

Granulomatous angiitis of the central nervous system, a pathologic entity associated previously with a fatal prognosis, is reported in a patient with Hodgkin's disease. Viral isolation, indirect fluorescent antibody, and electron microscopic studies performed on fresh cerebral tissue were negative. The granulomatous angiitis of the central nervous system in this patient remitted following therapy for Hodgkin's disease. The epidemiologic, clinical and pathologic data in all reported cases of granulomatous angiitis of the central nervous system suggest that it: 1) may have more than one etiology; 2) may not always be fatal; 3) is associated with varicella-zoster virus and Hodgkin's disease; 4) is one of two granulomatous reactions found in association with Hodgkin's disease; and when found with Hodgkin's disease, 5) may remit with adequate therapy for the lymphoma.     

Primary intraosseous verrucous carcinoma developing from a maxillary odontogenic cyst: case report

Primary intraosseous carcinoma (PIOC) is an extremely rare lesion, almost always occurring in cranial bones. The origin of this tumor, specific to the maxillae, is associated with the cells of the epithelial rests of Malassez. Among the histotypes which can be included in these neoplasms, verrucous carcinoma is of particular interest due to its rarity: only a single case has been reported to date. After a short survey of the literature, the authors describe a directly observed case of verrucous carcinoma arising from a maxillary odontogenic cyst.     

Tubular carcinoma developing within a recurring cystosarcoma phyllodes of the breast

Malignant alteration in cystosarcoma phyllodes is uncommon and almost always confined to the stromal component. A rare case of recurring cystosarcoma is reported. In the first recurrence, lobular carcinoma in situ was present within the tumor and the second recurrence revealed tubular carcinoma within the cystosarcoma. Epithelial proliferation of various sorts is not uncommon in cystosarcomas but only two previous instances of infiltrating carcinoma have been observed within these tumors. The problem of mammary carcinoma coexisting with cystosarcoma is reviewed and comparisons are made with a closely related neoplasm, the fibroadenoma.     

“Revertant” mammary solid papillary carcinoma in lymph node metastasis

A case of invasive carcinoma of mixed papillary and not otherwise specified ductal type with areas of solid papillary ductal carcinoma in situ(DCIS) is reported. The solid papillary areas were predominantly of low nuclear grade, but a small area of intermediate-grade solid papillary neoplasm was also seen within the tumor, together with an area suggestive of microinvasion. The massive regional nodal tumor load consisted of invasive papillary carcinoma and revertant low-grade solid papillary carcinoma with no myoepithelial cells around the circumscribed solid papillary areas. This is the first report of a solid papillary pattern simulating intraductal carcinoma in lymph nodes, and the first time that a solid papillary carcinoma is reported in association with invasive papillary carcinoma. The case suggests that mammary carcinomas with a solid papillary pattern may sometimes be of higher grade than usual, and do not always represent a DCIS, but may be invasive.     

Glomus tumour of the hard palate

Glomus tumour of the nose and the nasopharynx were reported by Rosenwasser in 1948. House in 1972 reported two cases of chemodectoma in the nasopharynx. Girgis and Fahmy (1973) have demonstrated the presence of paraganglionic tissue surrounding the maxillary artery. Guild (1953) has demonstrated presence of paraganglionic tissue near the tympanic branch of the vagus nerve. As the palate is supplied by branches of the maxillary artery and with twigs from the vagus nerve, there is always a possibility of a paraganglioma arising in this region.