颅外固定牵引矫治重度小下颌畸形伴阻塞性睡眠呼吸暂停低通气综合征六例报告

目的探讨使用颅外固定牵引装置矫治儿童患者小下颌畸形伴发阻塞性睡眠呼吸暂停低通气综合征（obstructive sleep apnea hypopnea syndrome，OSAHS）。方法6例均为双侧颞下颌关节强直伴重度小下颌畸形及OSAHS患者。男性4例，女性2例，年龄1．5～14岁。全麻下颌下手术入路，下颌骨体部截骨并在远心骨段小型钛板固定，然后安置颅外固定牵引装置并与下颌骨上的钛板连接。同内置式牵引成骨方案。结果6例手术前后面型、后气道间隙和多道睡眠监测结果均有明显改变，患者术后睡眠及日间状态恢复正常，未发生术后不良反应。4个月后拆除牵引装置及固定钛板，牵引区新骨生长良好。结论治疗重度小下颌畸形伴OSAHS时颅外固定牵引装置具有手术简便、成骨质量好、牵引幅度大、牵引方向精确并可调等优点，特别适于下颌骨体积过小、无法安放较长内置式下颌骨牵引器的儿童患者。     

内置式牵引成骨技术治疗颌骨畸形

目的 :探讨内置式牵引成骨技术在不同类型的牙颌面畸形治疗中的应用。方法 :应用 2种类型的内置式牵引装置 ,为严重的小颌畸形、上颌后缩畸形、半侧颜面萎缩畸形和下颌骨缺损畸形患者行下颌骨体水平方向延长、上颌骨水平前徙、下颌升支与上颌骨同期垂直向延长以及下颌骨体部双端式牵引延长 ,共 5例。结果 :5例牵引成骨手术 ,部分病例辅助正颌外科手术 ,均达到术前设计要求 ,临床效果满意。 2例因牵引方向导致的错牙合问题 ,在牵引结束时及时得以纠正。无伤口裂开、感染、骨坏死、骨不连等并发症。结论 :应用内置式牵引成骨技术可重建面部轮廓 ,恢复理想的咬合关系和口颌功能 ,创伤小 ,安全可靠     

内置式牵张成骨术在矫治火器伤性下颌骨畸形中的应用

目的:探讨内置式牵张成骨术矫治火器伤性下颌骨畸形临床应用的可行性。方法:为3例火器伤性下颌骨畸形患者延期(伤后2～3个月)行内置式牵张成骨术。术中常规截骨,制作骨转移盘,固定内置式骨牵张器,术后1周以每日1 mm的速度行骨牵引(8～22 mm)。固定期拍曲面断层片观察新骨生成及畸形矫治状况。结果:治疗按计划完成,无感染等并发症,骨牵引顺利完成;固定期3个月时,新生骨骨质、骨量良好,下颌骨畸形矫治效果满意,咬合关系良好。结论:在早期合理清创基础上,延期牵张成骨术可有效地矫治火器伤性下颌骨畸形,值得推广。     

牵引成骨术联合正畸治疗重度小颌畸形1例

目的探讨应用下颌骨牵引成骨术联合正畸治疗重度小颌畸形患者下颌骨严重发育不足及咬合关系紊乱的疗效。方法对1例继发于颞下颌关节强直的重度小颌畸形的成人患者,经多学科会诊,确定采用自体肋软骨移植重建右侧下颌髁突,同期行双侧下颌骨牵引成骨术,并联合术后正畸治疗。结果患者经外科和正畸联合治疗后,面形及咬合功能均获得较满意的效果。结论下颌骨牵引成骨术联合正畸治疗成人重度小颌畸形可以获得较为满意的效果。     

下颌前突畸形的正颌外科矫治

目的 总结正颌外科矫治下颌前突畸形的临床经验。方法 对32例下颌前突畸形患者进行了正颌外科手术，其中12例行双侧SSRO，4例行双侧IORO，10例行双侧IVRO，5例行上下颌前部根尖下截骨，1例行下颌骨体部截骨，同期搭配施行水平截骨颏成形术12例，畸形涉及上颌骨行LeFortⅠ型截骨9例。结果 32例下颌前突畸形患者术后外观及功能均获得满意效果。并发症有术后下颌前突轻度复发4例，明显复发1例，下颌骨升支骨折一侧1例，下牙槽神经一侧断离1例，结论 随访结果显示应用IVRO，SSRO等术式治疗下颌前突畸形只要术式选择及操作得当，能获得较满意效果。文中就手术方法，注意事项及并发症等进行了讨论。     

牵引成骨在下颌骨治疗中的应用研究

牵引成骨术(distraction osteogensis,DO)也称牵张成骨术.自McCaahy等将下颌骨牵引成骨术引入临床以后,特别是内置式颌骨牵引器的问世,这一技术被广泛采用,并不断被改进,适应症逐步拓宽,笔者总结了2000～2006年共21例采用牵引成骨术治疗的病例,对结果进行分析,以更好的掌握适应症,减少并发症,提高治愈率.     

骨牵引技术治疗TMJ强直小下颌畸形伴阻塞性睡眠呼吸暂停低通气综合征

目的:探讨牵引成骨术(d istraction osteogenesis DO)在治疗小下颌畸形伴阻塞性睡眠呼吸暂停低通气综合征(obstructive sleep apnea hypopnea syndrom e,OSAHS)中的应用。方法:9例小下颌畸形伴OSAHS患者行下颌骨牵张成骨术,3个月后行颞下颌关节成形术,术前术后行头颅侧位测量和多导睡眠监测仪测试。结果:9例牵引完成后所有患者后气道间隙(posterior airway space,PAS)值扩大,睡眠呼吸暂停综合指数下降,血氧饱和度增加,OSAHS症状消失或减轻,面部畸形得到明显改善。结论:DO技术在矫治颞下颌关节强直导致的小下颌畸形伴OSAHS中具有重要的临床价值。     

个体化内置式牵引器在修复下颌骨部分缺损中的应用

目的：应用个体化设计的内置式下颌骨牵引器,通过牵引成骨技术修复下颌骨部分缺损。方法：对因肿瘤行下颌骨部分切除的2例患者,术前根据头颅三维模型,设计个体化内置式牵引器,同期（1例）行肿瘤切除与牵引成骨手术,或二期1例行牵引成骨手术,运用转移盘牵引方式修复下颌骨部分缺损,固定期8～9个月,行X线及CT检查。结果：2例患者均成功进行了牵引器植入手术,术后牵引顺利,其中（1例）出现伤口感染,给予抗生素后得到控制,未影响牵引成骨治疗的进行。2例患者新骨形成均良好,转移盘远端骨质连接间隙处在拆除牵引器时需以植骨或钛板固定。结论：个体化设计的内置式下颌骨牵引器,可以根据不同患者颌骨缺损情况,进行一次性复杂牵引成骨,修复下颌骨部分缺损。     

牵张成骨联合正颌正畸治疗成人严重小下颌畸形

目的：探讨牵引成骨技术联合正颌正畸治疗重度小下颌伴偏颌畸形患者下颌骨严重发育不足及咬合关系紊乱的疗效。方法：对2例继发于儿童时期颞下颌关节损伤的小下颌伴偏颌畸形患者采用牵张成骨技术进行治疗。手术行双侧下颌角处截骨,安置牵引器,延长下颌升支及下颌体。第二期在拆除牵引器后进行正畸治疗,继而采用正颌外科方法进一步矫正颌面畸形及咬合关系,术后正畸治疗矫正咬合关系,排齐牙列。结果：2例患者均顺利完成治疗。下颌骨最小牵引距离25 mm,最大牵引距离30 mm,牵引区成骨良好,SNB角由术前平均67°增加到术后80°,小下颌及偏颌畸形得以矫治。联合正颌外科及正畸治疗后,面形及咬合功能均获得满意效果。术后经过2年6个月随访,未见复发。结论：联合应用牵张成骨和正颌外科技术并配合正畸治疗是矫治成人重度小下颌不对称性牙颌面畸形的有效治疗方案。     

牵引成骨术治疗儿童单侧颞下颌关节强直伴OSAHS 4例报道

目的:评价牵引成骨术治疗儿童单侧颞下颌关节强直伴阻塞性睡眠呼吸暂停低通气综合征(OSAHS)的治疗效果。方法:4例儿童单侧颞下颌关节强直伴发OSAHS患者,男女各2例,年龄5～13岁(中位年龄6.5岁)。均采用颞下颌关节成形术以恢复开口功能,下颌体牵引成骨术治疗OSAHS;其中3例行同期手术,1例行分期手术;单侧和双侧下颌体牵引各2例。固定期约3个月时行呼吸监护仪监测(PSG)复查和牵引器拆除术。结果:4例患儿OSAHS症状均消失,平均AHI由术前的42.7降到4.9,平均最低血氧饱和度由术前的74.3%上升到89.8%;平均开口度由6.5mm增加至25.5mm;面部畸形得到满意矫正。经过平均38.1个月(13～58个月)的随访,无1例复发。结论:下颌骨牵引成骨术联合颞下颌关节成形术能够有效地治疗儿童单侧颞下颌关节强直及其伴发的OSAHS、面部不对称畸形,并且可以同期手术。     

正颌外科治疗颞下颌关节强直伴阻塞性睡眠呼吸暂停综合征

目的 评价正颌外科手术治疗颞下颌关节强直伴阻塞性睡眠呼吸暂停综合征(OSAS)的效果。方法 12例颞下颌关节强直伴OSAS患者(男4例，女8例，年龄10～25岁，平均18．4岁；双侧颞下颌关节强直8例，单侧颞下颌关节强直4例)，采用颞下颌关节成形术、下颌矢状劈开前徙术、颏前徙成形术、舌骨悬吊术以及牵张成骨术移动下颌骨和舌骨。术后随访3～36个月。结果 12例患者张口度由术前的0～2mm增大到术后25～40mm；术后患者颜面形态明显改善；其连续血氧饱和度最低值由术前的42％提高至术后的90％以上，睡眠呼吸障碍解除和睡眠质量获得提高。结论 在颞下颌关节强直伴OSAS患者的治疗中，行颞下颌关节成形术的同时，辅助正颌外科手术，不仅可以增大患者的张口度，而且还能解决患者下颌后缩的畸形，同时解除上气道狭窄，从而缓解或纠正患者的低氧血症。     

Intraoral distraction osteogenesis for the correction of facial deformities following temporomandibular joint ankylosis: a modified technique

The aim of this study was to evaluate the feasibility of transoral bimaxillary distraction osteogenesis before releasing temporomandibular joint (TMJ) ankylosis using intraoral mandibular distractors. Nine patients (5 males, 4 females) aged 14-35 (mean 19) years were included. A bilateral Le Fort I osteotomy was performed together with a mandibular osteotomy on the affected side(s). An intraoral distractor(s) was inserted in the lower jaw, followed by an intermaxillary fixation (IMF) to maintain preoperative dental occlusion. The distractor was activated, after a latency period of 5-7 days, 2 times daily by 0.5 mm. There followed a consolidation period of 6-8 weeks. TMJ ankylosis was then released via a peri-auricular incision, a gap arthroplasty was performed, and mandibular movement was established after removal of the IMF and distractor. Optimal results were achieved clinically and radiologically with minimal relapse and complications. Apart from minor complaints, the distraction process was smooth and tolerable in all cases. Total mandibular elongation ranged from 17 to 25 mm (20.7 mm). Occlusal canting decreased to 0 degrees in 7 patients and to 1 degree in 2 patients (mean 0.2 degrees). After a mean follow-up period of 17 months, a mean postoperative mouth opening of 34.7 mm was achieved (0.6 mm preoperatively) and no re-ankylosis was detected. Intraoral distraction of a deformed mandible and maxilla before releasing TMJ ankylosis is a feasible and perhaps advantageous technique.     

Gap arthroplasty combined with distraction osteogenesis in the treatment of unilateral ankylosis of the temporomandibular joint and micrognathia

Our aim was to evaluate the efficacy of simultaneous gap arthroplasty and distraction osteogenesis (DO) in the treatment of unilateral ankylosis of the temporomandibular joint (TMJ) in patients with micrognathia. During the period January 2000-December 2006, 11 patients with unilateral ankylosis of the TMJ and micrognathia were treated with simultaneous gap arthroplasty, mandibular osteotomy, and implantation of a distractor. Mouth opening exercises were started on the first postoperative day and distraction on the fifth postoperative day. All patients had satisfactory mouth opening at follow-up, the mean (range) being 32.4 (28-37) mm in 13 to 58 months' follow-up. Mean length (range) of the mandibular body increased by DO was 12.4 (7-15) mm. Facial asymmetry was corrected and satisfactory occlusions achieved with the help of postoperative orthodontic treatment. We conclude that DO and gap arthroplasty can be used simultaneously in the treatment of patients with ankylosis of the TMJ and micrognathia.     

牵引成骨和正颌外科技术在TMJ强直继发OSAS治疗中应用

目的　 30例 TMJ强直伴阻塞性睡眠呼吸暂停综合征 (OSAS)患者 ,单侧 TMJ强直 18例 ,双侧强直 9例 ,TMJ强直术后 3例。患者均有严重的小下颌畸形并伴轻度的上颌后缩畸形 ,睡眠呼吸暂停指数 AI>5 ,且睡眠时血氧饱和度都有不同程度的降低。方法　应用术前后临床检查、头影测量分析和夜间多导睡眠检测筛选患者和评价治疗效果。采用电脑辅助的诊断和手术模拟及预测系统 ,获得充分扩展口咽和纠正颌面畸形的最佳手术方案 ,以 TMJ重建、牵引成骨和正颌外科方法治疗患者。结果　本研究有 15例患者接受患侧下颌升支倒置 TMJ重建、植骨前移 ,健侧升支矢状劈开、下颌前移和颏前移成形术 ;其中有 3例行二期的上颌的 L e Fort 截骨术。 6例行双侧 TMJ重建、植骨前移下颌和颏成形术。 3例施行同期双颌截骨前移和颏成形术 ;6例行单或双侧 TMJ重建、牵引成骨术。全部病例创口均正常愈合 ,无一例感染。术后复查 (平均 5 .2 5年 ,最短 1年 ,最长 8年 ) :1例术后 TMJ强直复发 ,余张口度均在 3cm以上 ;术后颌面形态获得明显改善 ;2 9例患者眠眠呼吸障碍解除和睡眠质量获得提高 ;1例 AI>5 ,睡眠呼吸障碍改善不明显。结论　 TMJ强直继发 OSAS的治疗既要兼顾关节强直的解除 ,又要矫正牙颌面畸形 ,更不容忽视睡眠呼吸障碍的治疗 ;     

颞下颌关节强直的牵引成骨治疗

目的探讨牵引成骨技术在颞下颌关节强直治疗中的应用。方法应用内置式牵引器治疗8例单侧颞下颌关节强直患者,患侧升支区制备一个1.5～2.0cm颊舌向等宽的骨间隙,并去除喙突,恢复开口度,升支后缘方块截骨,截骨块保留翼内肌附着,与下颌骨间安装牵引器,术后采用升支牵引成骨术,每日牵引1mm,分2次完成,重建颞下颌关节结构及恢复颞下颌关节功能,并坚持开口训练18个月以上。结果经牵引成骨后,患者牵引间隙成骨良好,新形成的关节形态得到改建,升支高度延长1.2～2.1cm,开口度达到正常。结论牵引成骨是治疗颞下颌关节强直的有效方法。     

Unilateral mandibular widening with distraction osteogenesis

Mandibular widening with distraction osteogenesis (DO) has been shown to be an acceptable and stable treatment modality. Mandibular widening with DO is useful in relieving crowding and for restoring a rotated mandibular arch segment to its original condition. This is especially true when a patient has a unilateral medial displacement of the proximal segment of the mandible or a unilateral Brodie bite. This case report shows the application of mandibular widening with DO for skeletal reconstruction and prosthodontic preparation in a patient with unilateral medial displacement of the proximal segment of the mandible. The design of the osteotomy line and the placement of the distractor must be taken into consideration in a detailed procedure for unilateral mandibular widening of the mandible.     

Two-stage treatment of TMJ ankylosis by early surgical approach and distraction osteogenesis

Temporomandibular joint (TMJ) ankylosis is characterized by the formation of bone or fibrous adhesion of the anatomic joint components, which replaces the normal articulation and limitation of mouth opening. Early surgical intervention is considered as a treatment procedure to release the joint ankylosis and to maintain the function of the joint. Longstanding temporomandibular joint ankylosis which starts during the active growth period in early childhood resulting in facial asymmetry. Thus, the importance of the evaluation for the facial asymmetries and unfavorable remodeling of the mandible has to be considered during the initial treatment planning. Further operations, either osteotomies or distraction osteogenesis, are required for the treatment of maxillofacial deformities. The present study reports a case of unilateral TMJ ankylosis treated by interpositional arthroplasty prior to distraction osteogenesis for the treatment of mandibular secondary deformity. Various treatment procedures and timing protocols are reviewed and discussed.     

Temporomandibular joint bony ankylosis: comparison of treatment with transport distraction osteogenesis or the matthews device arthroplasty

Temporomandibular joint (TMJ) bony ankylosis with micrognathia is a rare congenital condition that is difficult to treat and may result in recurrence. In a series of affected patients, we compared two new methods of treatment: transport distraction osteogenesis and Matthews Device arthroplasty. All patients had computed tomography scan documented bilateral TMJ bony ankylosis. Group I (transport distraction osteogenesis) underwent distraction advancement of the mandible (for micrognathia) followed by resection of the condyles, recontouring of the glenoid fossas with interposition temporoparietal-fascial flaps, and transport distraction osteogenesis of mandibular rami segments. Group II (Matthews Device arthroplasty) underwent all of the above procedures except for transport distraction osteogenesis. Instead, the Matthews Devices were anchored to the temporal bone and mandibular rami. Hinged arms allowed for motion at the reconstructed TMJ. In both groups, patients underwent extensive postoperative therapy. Preoperative, postoperative, and follow-up lateral cephalograms were obtained, and incisor opening distances were recorded. All patients but one had severe micrognathia (n = 9). For group I (transport distraction osteogenesis), mean age was 6.8 years. and mean advancement was 28.5 mm. For group II (Matthews Device arthroplasty) mean age was 8.2 years, and mean advancement was 23.5 mm. In group I (transport distraction osteogenesis), mean incisor opening was 1 mm preoperatively and 27.5 mm postoperatively; however, it relapsed to 14.3 mm by 12.5 months follow-up (48% relapse). Mean incisor opening in group II (Matthews Device arthroplasty) was 3.9 mm preoperatively and 33.4 mm postoperatively and remained at 30.6 mm after 11.1 months follow-up (8% relapse). One patient in group I (transport distraction osteogenesis) underwent surgical revision because of relapse. Our data showed that for congenital TMJ bony ankylosis both transport distraction osteogenesis and Matthews Device arthroplasty techniques were successful initially; however, the Matthews Device arthroplasty avoided long-term relapse.     

Treatment of temporomandibular joint ankylosis in children: is it necessary to perform mandibular distraction simultaneously?

Temporomandibular joint (TMJ) ankylosis in children disturbs not only mandibular growth, but also facial skeletal development. Costochondral graft was used to ensure growth, but it had proven to be unpredictable. The authors evaluate retrospectively 41 patients who underwent temporomandibular joint reconstruction during the last 10 years. Twenty were treated by costochondral graft, 15 by arthroplasty, and 6 by other surgical procedures, and they were excluded. The etiology was septic in 54% of the cases. Follow-up was at least 12 months in all cases. Arthroplasty was a quicker and easier procedure than the costochondral graft, reducing operating time, risk of blood transfusion, and hospital stays and costs. It also was associated with less risk of reankylosis, 13%vs 25%. Furthermore, it was associated with a minor morbidity and secondary complications. Seventy-five percent of the patients treated with bone graft required additional secondary surgery. Radiographically, the authors observed a remodeled neocondyle at the level of proximal mandibular end in cases treated by arthroplasty. On clinical examination, patients showed variable degrees of facial deformity and an unknown potential of mandibular growth after TMJ arthroplasty. The authors also observed improved clinical and radiologic appearance after ankylosis correction. Is it reasonable to perform ankylosis release and mandibular distraction simultaneously without knowing which patients will be able to experience growth with time? In that case it would be necessary a predict growth to apply the exact amount of mandibular distraction for obtaining stable results. Timing of mandibular distraction, after TMJ arthroplasty is performed and mandibular function restored, must be specific to each patient's needs, assuring the best distraction conditions and planning. The authors present their treatment protocol, including TMJ joint arthroplasty with temporal muscle interposition, and mandibular distraction osteogenesis, as a second procedure, to correct residual asymmetry or retrognathism if necessary.     

Pre-arthroplastic mandibular distraction osteogenesis for the correction of OSA in TMJ ankylosis: a prospective observational study of 25 cases

Introduction

In severe TMJ ankylosis cases, the lack of growth of the mandible creates an anatomically narrow airway with a reduced pharyngeal airway space [PAS] which predisposes these patients towards obstructive apnoea [OSA]. There is evidence in the literature that such patients experience severe discomfort during physiotherapy if such airway abnormalities are not corrected prior to ankylosis release. This eventually leads to non-compliance towards physiotherapy and increases the risk of re-ankylosis.

Objective

In our study, pre-arthroplastic mandibular distraction osteogenesis [DO] was used to increase the PAS and resolve the underlying OSA prior to releasing the ankylosis.

Materials and methods

Twenty-five cases of TMJ ankylosis with micrognathia and OSA were included in this prospective observational sleep study. They were further divided into a paediatric group [14 subjects] and an adult group [11 subjects]. All cases presented with a history of onset of ankylosis during childhood [before the completion of craniofacial growth] as result of which there was a lack of forward growth of the mandible. Subjects included in our study underwent initial DO of the mandible followed by a second procedure for distractor removal and ankylosis release. Questionnaires, lateral cephalograms and sleep studies were taken pre-operatively (T0), immediate post-distraction to the desired length (T1) and 12 months post the distractor removal and ankylosis release (T2). The parameters studied were PAS width, apnoea hypopnea index [AHI], O₂ saturation, mouth opening and mandibular advancement.

Results

The paediatric group variables were as follows: mean PAS width which increased from 3.5 mm [T0] to 9 mm [T2], mean AHI which decreased from 48.04 [T0] to 3.60 [T2], mouth opening which increased from 4.5 mm [T0] to 34 mm [T2] and mean O₂ saturation which increased from 89.86% [T1] to 96.88% [T2]. The adult group variables were as follows: mean PAS width which increased from 5 mm [T0] to 11 mm [T2], mean AHI which decreased from 31.45 [T0] to 1.43 [T2], mouth opening which increased from 5 mm [T0] to 34 mm [T2] and mean O₂ saturation which increased from 92.01% [T0] to 96.84% [T2]. Statistical analysis revealed that DO of the mandible significantly improved OSA by increasing the PAS which was evident by the lower AHI score. Mouth opening was also significantly improved post ankylosis release and maintained at the T2 interval. Ten subjects followed up beyond the T2 interval [mean 28 months post ankylosis release] and their data also revealed positive compliance towards physiotherapy, adequate mouth opening and maintenance of normal AHI.

Conclusion

Pre-arthroplastic mandibular DO has proved to be a successful modality for treatment of OSA in TMJ ankylosis patients with stable results at 12 months. By resolving the narrow airway and OSA, compliance towards physiotherapy was improved thus reducing the risk of re-ankylosis in the long term.