水疱样毛母质瘤一例

患者男,75岁.因颈后部肿物3月余,于2009年11月来我科就诊.就诊前3个月摸到颈后部一绿豆大小硬结,无明显不适,未予处理.此后自觉皮损迅速增大,但无局部与全身不适感.否认发疹前局部有外伤史.既往体键,否认心、肺、肝、肾、脑重要脏器疾病史.家族中无遗传性疾病史及类似疾病患者.     

水疱型毛母质瘤一例

正临床资料患儿,女,13岁。因右侧肩部结节5个月,出现水疱样外观1个月,于2015年7月29日就诊。5个月前,患儿右侧肩部出现一蚕豆大小淡红色质硬结节,缓慢增大;1个月前结节表面出现水疱样外观,无自觉症状。自起病以来,患儿无发热、肌无力、肌肉酸痛及肌肉萎缩等全身症状。患儿既往体键,无传染病及遗传病史,家族成员中无类似疾病患者。皮损局部无外伤史或蚊虫叮咬史。体格检查:一般情况可,     

水疱型毛母质瘤一例

患者,女,23岁。1年前蚊虫叮咬后右上臂出现两处皮下结节伴疼痛,3个月前两处皮损均增大为红色囊性肿物。病理特征符合水疱型毛母质瘤。MRI提示：脂肪层见椭圆形乳头状长T1短T2信号,凸向皮肤表面,外缘长T2信号。手术完整切除,创面愈合良好。目前随访未复发。     

水疱型毛母质瘤

<正>患儿男,15岁。主诉:左上臂肿物3个月余。现病史:患儿3个月前无明显诱因左上臂出现一绿豆大红色结节,因无自觉症状未予诊治,后结节逐渐增大、变软,遂于2016年2月26来哈励逊国际和平医院皮肤科就诊。既往史、个人史及家族史:患儿既往体健,否认发病前病变部位有蚊虫叮咬史及外伤史。家族中无类似疾病患者。体格检查:一般情况良好,各系统检查均正常。全身未触及增大的浅表淋巴结。     

毛母质瘤一例

正临床资料患者,男,24岁。主因颈后肿物2年余,于2015年3月6日就诊。2年前,患者颈后中部皮下出现一小指大肿物,无不适,缓慢生长,未诊治。既往体健;否认局部有外伤史;无此类疾病家族史。体格检查:各系统无异常。皮肤科情况:颈后中部可见一皮肤稍隆起区域,表皮正常,皮下可扪及一直径约3cm的深在结节,质地较硬,稍有弹性,可移动,无波动感,表面皮肤触觉、痛温觉正常。实验室检查:     

水疱型毛母质瘤1例

患儿男,11岁.因背部结节6个月,出现水疱样外观2个月,于2011年4月16日至我院就诊.患儿于6个月前上背部出现一绿豆大的红色质硬结节,缓慢增大,无自觉症状.2个月前结节表面出现水疱样外观,渐增大.患儿发病前1个月局部有昆虫叮咬史.既往体健,父母非近亲结婚,家族中无类似疾病史.     

水疱型毛母质瘤1例

患者,男,12岁。右侧颈部及右上臂囊性肿物2年。皮损组织病理示:表皮正常,真皮内见镜影细胞及嗜碱性粒细胞浸润,可见多处钙化区,其周围被纤维组织包绕。诊断:水疱型毛母质瘤。     

水疱型毛母质瘤1例

患者女,16岁.右上臂单个皮下结节2个月.表面出现水疱样外观1个月,起初局部有压痛感,现无不适,至就诊时"水疱"一直未破.发病前局部无外伤史.既往体健,患者家族中无类似疾病患者.     

水疱型毛母质瘤一例

患者,女,11岁.左上臂水疱样肿物1年.组织病理示真皮内见镜影细胞、过渡细胞及嗜碱性细胞构成界清团块,胶原纤维稀疏,周围可见淋巴细胞和多核巨细胞浸润.诊断:水疱型毛母质瘤.治疗:手术切除.伤口愈合良好.     

水疱型毛母质瘤1例

报告水疱型毛母质瘤1例。患者男,26岁,右肘部屈侧皮肤肿物7年。皮肤科检查：右肘部屈侧可见一约3.0 cm×3.0 cm×1.0 cm大小类圆形松弛的淡红色水疱,隆起皮面,边界清楚,无破溃与渗液,触之有波动感,水疱基底部可扪及一约1.5 cm×1.0 cm×0.3 cm大小的质硬结节,活动度差,形状欠规则,触压痛不明显。皮损组织病理：表皮正常,肿瘤位于真皮内,肿瘤细胞团块周围可见扩张淋巴管,其中充满淋巴液,肿瘤团块由基底样细胞及影子细胞构成。诊断为水疱型毛母质瘤。予手术完整切除,创面愈合良好。目前随访未复发。     

穿通性毛母质瘤1例

报告1例穿通性毛母质瘤。患者女,60岁。因背部结节4个月就诊。皮肤科检查示背部有一突出皮面的紫红色结节,直径0.9cm结节中心有破溃。予以手术切除。组织病理检查示穿通性毛母质瘤。     

Pilomatricoma with a Bullous Appearance

A 15-year-old Japanese girl had an asymptomatic nodule on the right thigh of seven months' duration. The clinical appearance was similar to that of a bulla. There was a history of blunt trauma from dog scratch to the skin over the tumor shortly before tumor growth. Histopathological findings were consistent with pilomatricoma. In the overlying dermis, the collagen bundles were compressed to the tissue surrounding the tumor and the large space was seen. Around the tumor, some dilated endothelium-lined vascular channels were found, which were identified as lymphatic vessels.     

Perforating pilomatricoma: transepithelial elimination or not

We present a 56-year-old woman with a perforating pilomatricoma in the left eyebrow region. Histologically, the tumor consisted mainly of basophilic cells and shadow cells, and the tumor components were being eliminated through an ulcer with damage to the epithelial structures. In past reports of perforating pilomatricoma, this elimination pattern has often been described as transepithelial elimination. In many patients with perforating pilomatricoma, elimination is accompanied by ulceration and epithelial damage. Mehregan recently stated that elimination accompanied by epidermal necrosis and superficial ulceration constituted one form of transepithelial elimination. Epidermal necrosis and ulceration generally constitute severe damage. However, when Mehregan first proposed the concept of transepithelial elimination, it was defined as a phenomenon with relatively little or no damage to the epithelial structures, differentiating it from other types of elimination. This original definition makes transepithelial elimination a unique and interesting phenomenon, and its most important feature is that there is relatively little or no damage to the epithelial structures. Therefore, the terms "epidermal necrosis" and "ulceration" should not be used in association with transepithelial elimination. Hence, in patients with perforating pilomatricoma, the elimination of tumor components from ulcers with damage to the epithelial structures, as seen in the present case, should not be described as transepithelial elimination.     

穿通性毛母质瘤

报告1例穿通性毛母质瘤.患儿女,10岁.左上臂外侧出现一红色丘疹,偶有疼痛,逐渐增至玉米粒大,中央破溃1年.皮肤科检查:左上臂后外侧见一玉米粒大的紫红色半球形结节,质硬,中央破溃呈脐窝状.经皮损组织病理检查诊断为穿通性毛母质瘤.     

Two cases of multiple giant pilomatricoma

Pilomatricoma is a skin appendage tumor manifestating as a firm, solitary lesion of the face and upper extremity. It generally measures 0.5 to 3.0 cm in diameter and is typically found in young people. We report a 29-year-old male and a 13-year-old girl who developed three and two protruding masses, respectively. The size of each tumor was larger than 5 cm. The histologic appearance showed sharply demarcated tumor lobules composed of eosinophilic shadow cells and basaloid cells. We describe two unusual cases of multiple giant pilomatricomas and review the literature, emphasizing the number and size.