Chronic Erythematous Plaque on the Leg of an 18 Month‐Old Boy

An adolescent girl with blond hair, her family, and classmates noted that her hair was progressively turning green. Initially the green color was thought to be secondary to chlorine from the local swimming pool. This was not the real cause. The chlorotrichosis was actually caused by an excessive amount of dissolved copper from copper pipes in the home plumbing system. Copper had leached from the plumbing and accumulated in the pipes because the rented house had been vacant for many months. Risk factors for chlorotrichosis include light‐colored hair, copper plumbing, long periods when the water was not thoroughly flushed out of the copper pipes, and frequent shampooing.     

Pancreatic Panniculitis in an 18‐Month‐Old with Complete DiGeorge Syndrome

Pancreatic panniculitis, characterized by tender, erythematous subcutaneous nodules occurring most commonly on the lower extremities, occurs in 2% of cases of pancreatic disease. We present a rare case of pancreatic panniculitis in a child with complete DiGeorge syndrome.     

Congenital Panfollicular Nevus in a 6‐Month‐Old Girl

A 6‐month‐old girl presented with an irregular nodule on the right lateral neck. The lesion, which superficially resembled a lymphangioma or mastocytoma, had been present since birth but had recently been growing. The patient was referred for surgical resection. Microscopic findings were compatible with a recently described rare hamartoma termed “panfollicular nevus,” which is a well‐circumscribed lesion containing aberrantly differentiated, clustered hair follicles in high density.     

Plica “Neuropathica” in an 11‐Month‐Old Boy

Plica neuropathica is an acquired, irreversible tangling and matting of scalp hair presenting as discrete masses. Many cases are reported in the literature, but it has never been reported in an infant. Herein we report the first case of plica neuropathica in an 11‐month‐old.     

Behavioral Characteristics in 18‐ to 36‐Month‐Old Toddlers with Atopic Dermatitis Compared with Healthy Children

Abstract: Some differences in behavioral characteristics have been attributed to atopic dermatitis (AD). In this study, AD patients compared with healthy toddlers had significantly higher scores in perceptual sensitivity and high pleasure in an early childhood behavior questionnaire (ECBQ). They tended to be more energetic and impulsive, and also showed more excitement when subjected to novel stimuli.     

Terra Firma‐forme Dermatosis in a 4‐Month‐Old Girl

Abstract: Terra firma‐forme dermatosis (TFFD) is an idiopathic condition characterized by asymptomatic, dirtlike, thinly papillomatous, hyperpigmented plaques which cannot be removed with routine cleansing, but clear with firm wiping with 70% isopropyl or ethyl alcohol. Commonly involved sites include the neck, trunk, and umbilicus. Most reports have described adolescents or young adults with a history of normal hygiene and vigorous but unsuccessful attempts at cleansing the affected areas. We describe a 4‐month‐old girl with TFFD, who is the youngest patient thus far reported with this condition.     

Pyogenic Granuloma in a 5‐Month‐Old Treated with Topical Timolol

A 5‐month‐old healthy female presented with a pyogenic granuloma on the cheek. The lesion was treated with topical 0.5% gel‐forming solution, resulting in regression of the lesion after 1 month of treatment and no recurrence at 8 months. This case suggests that treatment of pyogenic granulomas with topical timolol may be considered, especially when other treatment modalities are challenging or could result in significant scarring.     

Microcystic Adnexal Carcinoma in the Axilla of an 18‐Year‐Old Woman

Microcystic adnexal carcinoma (MAC) is an uncommon adnexal neoplasm with a predilection for the head and neck. The tumor rarely metastasizes but is locally aggressive and commonly demonstrates perineural invasion. MAC occurs most often in older adults. This report describes a young woman with a MAC in her left axilla who required two stages of Mohs micrographic surgery followed by a wide local excision because of persistent perineural invasion in close proximity to the brachial plexus. Other cases presenting in the pediatric age group are discussed.     

Cutaneous Presentation of Plasmablastic Post‐transplant Lymphoproliferative Disorder in a 14‐Month‐Old

Abstract: We present a 14‐month‐old female child who developed multiple erythematous nodules on her abdomen 5 months after liver and small bowel transplantation. Skin biopsy revealed a dense infiltrate of large cells in the dermal and subcutaneous layers with frequent mitotic figures. The cells were noted to have abundant cytoplasm, prominent nucleoli, and open chromatin. Immunohistochemical stains were positive for CD138, CD56, Ki67 (>90%), and lambda chain restriction. Rare mature B cells (CD20) and rare T cells (CD3) were noted. She was diagnosed with high‐grade post‐transplant lymphoproliferative disorder most consistent with plasmablastic lymphoma.     

Crohn's Disease Presenting as a Neutrophilic Dermatosis in a 5‐Month‐Old Boy

A 5‐month‐old boy with a previous history of failure to thrive and poor feeding was admitted to the hospital with failure to thrive, oral ulcers, and a generalized vesiculopustular rash that demonstrated a subcorneal pustule and neutrophilic infiltrate on histology. Esophagogastroduodenoscopy and flexible sigmoidoscopy biopsies demonstrated chronic active colitis with granulomas, consistent with the diagnosis of Crohn's disease. Our case represents, to our knowledge, the youngest person reported with this condition in association with Crohn's disease.