腹腔镜阑尾切除术与传统手术疗效的比较

目的:比较腹腔镜阑尾切除术(laparoscopic appendectomy,LA)与传统开腹阑尾切除术(open appendectomy,OA)的临床疗效。方法:随机将223例阑尾炎患者分为两组,LA组115例行LA,OA组108例行OA。比较两种术式的手术时间、平均住院费用、住院时间、术后镇痛剂应用、术后24h内肛门排气例数、放置引流管率、切口感染率等。结果:LA组术后24h内肛门排气时间、放置引流管率、切口感染率、平均住院时间、粘连性肠梗阻、镇痛剂应用例数与OA组的差异有统计学意义(P<0.05);两组手术时间差异无统计学意义(P>0.05);LA组住院费用明显高于OA组(P<0.05)。结论:LA具有手术损伤小,患者疼痛轻、康复快、住院时间短、并发症少等优点,可作为多数阑尾炎患者的首选术式。     

腹腔镜与开腹手术治疗急性阑尾炎临床疗效比较

探讨腹腔镜阑尾切除术(LA)治疗急性阑尾炎的临床效果。回顾性分析148例手术治疗的急性阑尾炎患者临床资料。其中68例行LA(LA组),80例行开腹阑尾切除术(OA组),比较两组手术时间、术中出血量、术后止痛药使用情况、手术切口长度、术后排气时间、术后引流时间、切口感染发生情况、住院时间、住院费用等。两组手术时间差异无统计学意义(P>0.05),住院费用LA组高于OA组(P<0.05),其余指标LA组均优于OA组(P<0.05)。急性阑尾炎患者行LA治疗效果更好,但费用相对较高。     

小儿腹腔镜阑尾切除术与传统阑尾切除术创伤反应的对比研究

目的比较腹腔镜阑尾切除术(laparoscopic appendectomy,LA)和传统阑尾切除术(open appendectomy,OA)治疗小儿阑尾炎创伤反应的差异。方法从2002年5月至2004年2月收治160例小儿阑尾炎,其中行LA69例,OA91例,术前和术后12h采血,应用酶链免疫吸附试验测定血清白介素6(IL-6)和C反应蛋白(CRP)水平。结果手术时间:LA组(33±15)min比OA组(45±9)min短(t=6·40,P<0·01);住院时间:LA组(4·3±1·5)d比OA组(6·6±1·2)d短(t=10·91,P<0·01)。术后切口感染:LA组1例(1·5%),OA组10例(11·0%),两者之间差异有统计学意义(χ2=4·19,P<0·05)。OA组IL-6术后较术前升高值明显高于LA组[(60±20)pg/ml比(28±8)pg/ml,P<0·01]。CPR在OA组术后升高值亦明显高于LA组[(83±11mg/L比(24±6)mg/L,P<0·01]。结论LA治疗小儿阑尾炎较OA手术时间短、创伤小、恢复快、并发症少。     

腹腔镜手术与开腹手术治疗小儿急性化脓性阑尾炎的疗效比较

目的:比较小儿急性化脓性阑尾炎行腹腔镜阑尾切除术(laparoscopic appendectomy,LA)与开腹阑尾切除术(open appendectomy,OA)的疗效。方法:回顾分析手术治疗的102例急性化脓性阑尾炎患儿的临床资料,其中57例行LA,45例行OA,对比两组手术时间、住院时间、肠道排气时间、引流管留置时间、引流管引流量、术后切口感染、术后腹腔脓肿形成及肠粘连等情况。结果:OA组手术时间短于LA组,差异有统计学意义(P0.05);LA组术后住院时间、肠道排气时间、引流管留置时间、引流管引流量、术后切口感染、腹腔脓肿发生率优于OA组,差异有统计学意义(P0.05);术后肠粘连发生率两组差异无统计学意义(P0.05)。结论:小儿急性化脓性阑尾炎行LA具有创伤小、康复快、并发症发生率低等优点,在适应证明确的患儿中值得推广应用。     

腹腔镜与开腹阑尾切除术治疗急性阑尾炎的效果分析

目的比较腹腔镜阑尾切除术(LA)与开腹阑尾切除术(OA)治疗急性阑尾炎的效果。方法随机将2016-03—2019-03间新郑市人民医院收治的188例急性阑尾炎患者分为2组,每组94例。对照组行OA,观察组行LA。结果观察组的手术时间及术后使用镇痛药例数、TNF-α等创伤反应指标水平、下床活动时间、胃肠功能恢复时间、并发症总发生率和住院时间均优于对照组,差异有统计学意义(P0.05)。结论对急性阑尾炎患者实施LA,创伤小、患者术后疼痛轻微、并发症发生率降低,有利于患者术后恢复。     

腹腔镜阑尾切除术与开腹阑尾切除术的对比研究

目的比较腹腔镜阑尾切除术(LA)与开腹阑尾切除术(OA)治疗急性阑尾炎的疗效和手术安全性。方法回顾性分析2010年7～12月期间的50例LA患者的临床资料,与同期55例施行OA的患者进行比较。结果 LA组与OA组在手术时间及术中出血量方面差异均无统计学意义(P>0.05);LA组术后肠功能恢复时间、下床活动时间及住院时间均明显短于OA组(P<0.05),LA组镇痛药使用率及术后并发症发生率明显少于OA组(P<0.05);但住院费用LA组高于OA组(P<0.05)。结论 LA在治疗阑尾炎方面有明显优势,值得推广。     

腹腔镜在急诊阑尾切除术中的应用

目的探讨腹腔镜在急诊阑尾切除术中的可行性及疗效。方法对200例急性阑尾炎随机分为传统的开腹阑尾切除术(Open appendectomy,OA)组100例和腹腔镜阑尾切除术(Laparoscopic appendectomy,LA)组100例,比较2组手术时间、住院时间、术后下床活动时间、术后切口感染等相关情况。结果所有患者均顺利完成手术,LA组有6例中转开腹,LA组住院时间、术后下床活动时间均少于OA组,差异有统计学意义(P<0.01),术后切口感染发生率LA组少于OA组,差异有统计学意义(P<0.05)。结论 LA具有创伤小、患者恢复快、并发症少、住院时间少等优点,是急诊阑尾炎患者可选用的有效手术方式。     

腹腔镜与开腹手术治疗慢性阑尾炎的meta分析

目的:应用meta分析探讨腹腔镜阑尾切除术(laparoscopic appendectomy,LA)与开腹阑尾切除术(open appendectomy,OA)治疗慢性阑尾炎的临床效果。方法:按系统评价原则,对2005年1月至2014年10月国内公开发表的有关LA与OA治疗慢性阑尾炎的随机对照研究进行系统评价。结果:共有12篇文献纳入研究,LA组645例,OA组709例。LA组出血量[WMD-10.946,95%CI(-13.270,-8.622)]、手术时间[WMD-5.628,95%CI(-7.439,-3.817)]及住院时间[WMD-2.957,95%CI(-3.687,-2.227)]均优于OA组(P0.05,随机效应模型),术中较OA组发现更多的腹腔粘连[RR 1.990,95%CI(1.382,2.863);P0.05,固定效应模型],术后慢性疼痛发生率低于OA组[RR 0.459,95%CI(0.305,0.691);P0.05,固定效应模型]。结论:与开腹手术相比,腹腔镜手术治疗慢性阑尾炎优势明显,尤其术前疑诊阑尾炎,而未能完全排除腹盆腔其他疾病时,腹腔镜手术可明确诊断并同时进行手术治疗,值得临床推广应用。     

腹腔镜与开腹手术治疗腹膜后位阑尾炎的临床疗效比较

目的比较腹腔镜阑尾切除术(laparoscopic appendectomy,LA)与开腹阑尾切除术(open appendectomy,OA)在腹膜后位阑尾炎治疗中的临床效果。方法回顾性分析2012年1月至2016年12月期间于笔者所在医院科室接受LA或OA的147例腹膜后位阑尾炎患者的临床资料,比较LA和OA的临床疗效。结果所有病例均未死亡、临床治愈。2组患者的手术时间和住院费用比较差异均无统计学意义(P0.05),但LA组的肠功能恢复时间、止痛药物使用率、术后感染率及住院时间均低于(短于)OA组,差异均有统计学意义(P0.05)。结论对于无腹腔镜手术禁忌的腹膜后位阑尾炎患者,LA较OA具有术后疼痛轻、恢复快、并发症少及住院时间短的优点。     

腹腔镜阑尾切除术的临床应用

目的对比腹腔镜阑尾切除术(LA)与开腹阑尾切除术(OA)的优缺点。方法回顾分析和对比近1年来106例腹腔镜阑尾切除术与同期施行的154例开腹阑尾切除术患者的临床资料。结果LA与OA的手术时间无明显差异(P>0.05),术后疼痛程度、术后住院时间、术后进食时间、术后下床时间、术后切口感染率、术后肠粘连发生率等方面LA明显优于OA(均P<0.05)。结论LA治疗急慢性阑尾炎较OA显示出明显优势,值得临床推广。     

腹腔镜治疗小儿穿孔性阑尾炎对血清C反应蛋白和降钙素原的影响

目的比较腹腔镜与开腹手术治疗小儿穿孔性阑尾炎手术前后血清C反应蛋白（C—reactive protein,CRP）和降钙素原（procalcitonin,PCT）的变化。方法采用前瞻性对照研究方法,将2010年6月～2012年10月临床诊断为穿孔性阑尾炎的78例患儿按家属意愿分为开放组（38例）和腹腔镜组（40例）。分别于术前0．5h、术后24h及48h采外周静脉血,分别用ELISA法和胶体免疫结合法测定血清CRP和PCT。结果2组血清CRP和PCT术前差异无显著性（P〉0．05）;术后24h较术前均明显升高（P〈0．05）,开放组CRP升高更明显（P=0．000）;术后48h腹腔镜组PCT已恢复至术前水平（P〉0．05）,腹腔镜组CRP和开放组CRP、PCT仍高于术前（P〈0．05）,且开放组明显高于腹腔镜组（P=0．000）。结论与开放手术相比,腹腔镜治疗小儿穿孔性阑尾炎引起CRP、PCT的变化较小。     

腹腔镜阑尾切除术的疗效及对并发症的影响

目的比较腹腔镜阑尾切除术（LA）与开腹阑尾切除术（OA）治疗急阑尾炎的临床疗效及并发症。 方法选择2014年1月至2015年5月收治的拟行阑尾切除术的阑尾炎患者118例,将患者随机分为试验组和对照组,每组59例,试验组采用LA术,对照组采用OA术,比较两组患者的临床效果及并发症发生情况,评价急性和慢性阑尾炎行腹腔镜手术的效果。 结果与对照组比较,试验组的手术时间延长,而住院时间、术后首次下床、排气及进食时间均明显缩短,24 h镇痛药物使用率也显著减少,住院费用明显增加（t=14.342、6.916、4.166、9.527、8.036,χ²=5.950,t=32.663,P<0.05）。试验组中急性阑尾炎患者34例,与25例慢性阑尾炎患者比较,手术时间、住院时间、术后首次排气及进食时间均明显延长,术中出血量明显增加（t=8.195、1.776、5.329、4.337、3.757,P<0.05）。试验组术后24 h、48 h时白细胞（WBC）、C反应蛋白（CRP）水平均显著低于对照组（P<0.05）;伤口感染、腹腔脓肿的发生率及总发生率显著低于对照组（χ²=4.827、4.140、10.602,P<0.05）。 结论LA治疗急性及慢性阑尾炎均安全有效,可减少术后并发症,促进术后恢复。     

腹腔镜与开腹阑尾切除术对小儿体液免疫和蛋白质代谢影响的比较

目的比较腹腔镜阑尾切除术（laparoscopic appendectomy,LA）和开腹阑尾切除术（open appendectomy,OA）术后体液免疫与蛋白质代谢指标水平的变化,评价LA在小儿阑尾疾病中的应用价值。方法阑尾炎患儿56例,依患儿家长意愿分为LA组和OA组,分别于术前、术后24h和72h采取外周静脉血检测免疫球蛋白IgG、IgM、IgA,补体C3、C4,C-反应蛋白（C-reactive protein,CRP）,血清前白蛋白（prealbumin,PA）和转铁蛋白（transferrin,TRF）,进行统计学处理,并比较2组患儿术后胃肠功能恢复时间、住院时间。结果2组术后24、27h免疫球蛋白IgM、IgA比较均无显著性差异（P〉0.05）。IgG在LA术后24h明显降低（P〈0.05）,术后72h与术前无差异（P〉0.05）;与OA组间比较,术后24、72h均有显著性差异（P〈0.05,P〈0.05）,但2组的变化均在正常生理范围内。补体C3在LA和OA术后24、72h组间比较无显著性差异（P〉0.05）。C4在LA术后24h较术前明显降低（P〈0.05）,但与OA组间比较无显著性差异（P〉0.05）。CRP水平在LA术后24、72h持续明显降低（P〈0.05,P〈0.05）,在OA术后则先有升高再降低（P〈0.05,P〈0.05）,组间比较术后24h有显著性差异（P〈0.05）,72h差异消失（P〉0.05）。PA在OA术后24h有明显降低（P〈0.05）,与LA组间比较有显著性差异（P〈0.05）。TRF在LA和OA术后24h均有降低（P〈0.05）,术后72h恢复接近术前水平（P〉0.05）,2组比较无显著性差异（P〉0.05）。与OA组比较,LA组胃肠功能恢复时间、住院时间明显缩短（P=0.000,P=0.000）。结论LA较OA对小儿机体体液免疫和蛋白质代谢影响小,LA更具有切口微小、胃肠功能恢复快、住院时间短的临床优点。     

腹腔镜阑尾切除术与开腹阑尾切除术治疗急性阑尾炎的临床疗效对比研究

目的 比较腹腔镜阑尾切除术(laparoscopic appendectomy,LA)与开腹阑尾切除术(open appendectomy,OA)的临床效果.方法 择取江阴市青阳医院普外科阑尾手术患者71例,根据手术方式的不同,分为LA组(37例,接受LA治疗),OA组(34例,接受OA治疗),比较两组患者手术情况、疼...     

腔镜阑尾切除术与开腹阑尾切除术的临床对比研究

目的 比较腹腔镜阑尾切除术与开腹阑尾切除术的临床治疗效果。方法 采用我院2008年1月至2011年6月间腹腔镜阑尾切除术的患者62例与传统开腹阑尾切除术102例做对比,比较两者在手术时间、术后胃肠功能恢复时间、住院时间和术后并发症等方面的发生率有无显著性差异。结果 两者在术后胃肠功能恢复时间、住院时间和术后并发症发生率上有显著性差异。结论 腹腔镜阑尾切除术相对于开腹阑尾切除术,术后胃肠功能恢复时间快,住院时间短,术后并发症少。     

Comparison of laparoscopic, open, and converted appendectomy for perforated appendicitis

BACKGROUND: Perforated appendicitis is associated with a significant risk of postoperative abdominal and wound infection. Only a few controversial studies evaluate the role of laparoscopy in perforated appendicitis. The significance of conversion from laparoscopy to open appendectomy for perforated appendicitis is not well defined. Statistical analysis was performed using Student's t-test. METHODS: Data on 52 patients with perforated appendicitis were prospectively collected and retrospectively reviewed. Among these patients, 18 had laparoscopic appendectomies (LA); 24 had open appendectomies (OA); and 10 had converted appendectomies (CA). The indications for either method were based on the attending surgeons's philosophy. Laparoscopic appendectomy was performed using a retrograde stapler technique. Operative time, hospital stay, ability to tolerate a liquid diet, and postoperative infectious complications were documented. RESULTS: No statistically significant difference in the operative time in minutes was found between the LA (114 +/- 29.3), CA (120.0 +/- 32.2), and OA (105.8 +/- 64.1) groups (p = NS). There was no statistically significance difference in length of stay (days) between the LA (9.2 +/- 4.1), OA (10.5 +/- 3.3), and CA (10.0 +/- 1.8) groups. The wound infection rate was less frequent in the LA group (0%) than in 0A (14%) and CA (10%) groups. The rate of intra-abdominal abscess infections (IAAs) and ileus were 22% and 28%, respectively, in LA group, 38% and 29%, respectively, in OA group, and 60% and 50%, respectively, in CA group. CONCLUSIONS: No difference in the rate of postoperative intra-abdominal abscesses exists between laparoscopic and open appendectomy for perforated appendicitis. Wound infections and ileus complicate the postoperative course of patients after laparoscopic appendectomy less frequently than after open appendectomy. The conversion of laparoscopic to open appendectomy for perforated appendicitis is associated with increased postoperative morbidity.     

Laparoscopic appendectomy in children after the learning curve.

OBJECTIVES: Despite its increasing popularity, several recent studies comparing laparoscopic appendectomy (LA) with open appendectomy (OA) in children have failed to demonstrate significant improvements in patient outcomes. Many series include the "learning curve," wherein surgeons inexperienced with laparoscopic techniques compare their results with results with OA with its extensive history. This study was designed to investigate outcomes in pediatric appendectomy patients managed by surgeons with extensive laparoscopic experience. METHODS: We preformed a retrospective review of 197 consecutive children undergoing appendectomy for presumed acute appendicitis from January 2002 through May 2004 at a university-affiliated community hospital by pediatric and general surgeons with extensive laparoscopic surgical experience. RESULTS: The study included 117 patients who underwent LA and 80 who underwent OA. Of 122 acute appendicitis cases, mean operating times were 47 minutes (LA) and 48 minutes (OA). The LA group (n=71) had a faster return to full diet (17.6 h vs. 28.6 h, P=0.0008), and shorter postoperative length of stay (LOS) (1.06 d vs. 1.66 d, P<0.0001) compared with the OA group (n = 51). Complication rates, time on intravenous (IV) antibiotics, and IV opiates were similar among the 2 groups. Complicated appendicitis cases (LA, n=34; OA, n=26) were similar with regard to LOS, return to normal bowel function, complication rate and time on IV antibiotics and opiates, but was associated with an increased operation time (LA, 65 min; OA, 51 min, P=0.02). CONCLUSIONS: Following the completion of the laparoscopic surgery learning curve, LA has a comparable operation time and results in a decreased postoperative LOS, and faster return to normal bowel function compared with OA in children with acute nongangrenous, nonperforated appendicitis.     

Laparoscopic appendectomy versus open appendectomy in children: another opinion

Laparoscopic appendectomy (LA) is a commonly performed procedure that is a safe alternative to conventional open appendectomy (OA). LA offers reduced parietal scarring, a shortened hospital stay, and an earlier return to normal activities. During a 13-month period (July 2001 to July 2002), data were collected regarding appendectomies performed in 113 children (<18 years) in our hospital. Patients were divided into two groups according to type of appendectomy received (OA, N = 59 versus LA, N = 54). The operative time, length of hospital stay, and postoperative complications were compared between the two groups. Operative time was similar in the OA and LA groups (1.20 +/- 0.46 versus 1.12 +/- 0.36 hours, respectively; P = 0.328). Patients receiving OA had significantly longer hospital stays than those receiving LA (4.69 +/- 3.45 versus 3.07 +/- 1.93 days, respectively; P = 0.002). The complication rate associated with OA was higher than that observed for LA (6.8% versus 3.5%), but this difference was not significant (P = 0.681). Patients receiving LA could begin drinking water earlier after surgery than postflatus OA patients (12-24 hours versus 3.2 days). The OA group had a higher rate of ruptured appendicitis than the LA group (13/59 versus 2/54), but similar rates of normal appendix was observed in both groups (13/59 versus 13/54). Three patients in the LA group were switched to OA. Although patients who underwent LA did not experience a significant decrease in complications compared with OA patients, they did have shorter hospital stays and postoperative NPO times. Therefore, LA seems to be a safe operation in children. It is ideal for overweight, adolescent females and patients in whom appendicitis is suspected. LA is not recommended for those with an appendiceal mass.     

小儿腹腔镜阑尾切除与开腹阑尾切除的临床对比研究

【摘要】 目的 对比研究小儿腹腔镜阑尾切除术(LA)与传统开腹阑尾切除术(OA)的临床疗效及安全性。方法 回顾性分析2009年1月~2012年12月期间进行LA和OA的93例小儿阑尾炎患者的临床资料,对两组手术时间、术中出血情况、术后恢复情况等进行统计对比分析。结果〓两组患儿手术及恢复顺利,术后无严重并发症。两组手术时间及术中出血量差异均无统计学意义(P>0.05);LA组术后肛门排气时间、下床活动时间、切口疼痛时间、术后住院天数均低于OA组,差异有统计学意义(P<0.05)。结论 与OA比较,小儿LA具有创伤小、并发症少,恢复快及美容等优势,是治疗小儿阑尾炎理想的手术方式。