Angiomyolipoma and renal cell carcinoma in same kidney.

A case of renal cell carcinoma and angiomyolipoma occurring in the same kidney in a patient without stigmata of tuberous sclerosis is reported. This case was managed as malignant renal tumor, and the patient underwent radical nephrectomy. Urologic and angiographic literature regarding angiomyolipoma is reviewed, and we find the neovascularity of this benign tumor is only rarely distinguishable from malignant renal tumor.     

Simultaneous contralateral renal transitional cell carcinoma and renal carcinoma: Case report of eight-year survival

This is the third reported case of simultaneous contralateral renal transitional cell carcinoma and renal cell carcinoma. The patient is an eight-year survivor with no evidence of metastases from simultaneous contralateral renal transitional cell carcinoma and renal cell carcinoma. General methods of management are discussed.     

Cystic renal cell and squamous cell carcinoma of single kidney with concurrent transitional cell carcinoma of ipsilateral ureter and urinary bladder.

We report on a case of the simultaneous occurrence of cystic renal cell and squamous cell carcinoma in a single kidney in a patient with concurrent transitional cell carcinoma of the ipsilateral ureter and urinary bladder. A review of the literature reveals this to be the first such occurrence.     

A clinical study on transitional cell carcinoma of the renal pelvis and ureter

Thirty-three patients in which transitional cell carcinoma was histologically diagnosed in the upper urinary tracts were statistically analyzed. Clinical analysis was done according to a new TNM system proposed by Akaza. Tumor grade and stage well correlated with survival. TS and TE group showed 89.5 and 17.1% 3-year survival, respectively. The survival rates showed significant difference between grade, 1, 2 and 3. T category and grade were also significantly correlated. Furthermore, histology and cytology were well correlated. Finally, prognosis in our series was significantly influenced by stage and grade of the tumor. Prognosis is considered to be good for 1) grade 1, 2) grade 2, superficial tumors with negative cytology, and 3) No and M0 cases. We emphasize that the new classification proposed by Akaza correlates well to survival and adapts well to the definition of regional lymph nodes.     

Bilateral renal cell carcinoma and synchronous occurrence of transitional cell carcinoma of renal pelvis

A case is reported of the unusual occurrence of a primary bilateral renal cell carcinoma and synchronous occurrence of a papillary transitional cell carcinoma of the renal pelvis in one kidney. The literature is reviewed.     

A case of ipsilateral pelvic transitional cell carcinoma and renal cell carcinoma

A case of ipsilateral pelvic transitional cell carcinoma and renal cell carcinoma (RCC), in an 82-year-old male is presented. We diagnosed this case as pelvic tumor preoperatively with retrograde pyelography and computed tomography. Operatively renal tumor was found and diagnosed as RCC. We thought it difficult to diagnose as RCC preoperatively. To date, this case is the 13th reported case diagnosed clinically.     

A case report: small cell carcinoma of the ureter

An 82-year-old woman visited our hospital with right flank pain. Computed tomography showed a right ureteral tumor. Urine cytology was class IV and cystoscopy demonstrated no obvious lesion. We performed right total nephroureterectomy and histopathological diagnosis was small cell carcinoma of the ureter. The serum ProGRP was slightly elevated postoperatively. Positron emission tomography showed a distant metastasis to the third lumber vertebra. She received two courses of chemotherapy (cisplatin and etoposide) and radiation therapy (8 Gy), but the distant metastasis was progressive. She died 6 months postoperatively.     

Simultaneous renal cell carcinoma and squamous cell carcinoma of kidney

A unique case of a collision tumor of the kidney composed of a renal cell carcinoma and a squamous cell carcinoma is reported. Although a few cases of combined tumors of the kidney have been reported previously, we were unable to find any similar case in the literature. Squamous cell carcinoma of the kidney usually behaves aggressively. Early diagnosis and surgical treatment before the tumor has extended beyond the capsule offer the best hope of cure.     

A case of synchronous contralateral renal cell carcinoma and ureteral transitional cell carcinoma

A case of synchronous contralateral renal cell carcinoma and ureteral transitional cell carcinoma is reported. A 56-year-old man, who had been incidentally found to have an abnormal mass in the upper pole of the right kidney on ultrasound sonography, was admitted on January 8, 1985. CT scanning and renal arteriography revealed right renal malignancy. Right radical nephrectomy was performed and histological examination showed adenocarcinoma, granular cell type of the right kidney. He was discharged on February 3, 1985. Two months postoperatively, he was rehospitalized for macroscopic hematuria. Left retrograde pyelogram showed obstruction at middle ureter and cytology of urine from left ureter was positive. So a left ureteral tumor was suspected, and partial resection of left ureter and ureteroureterostomy were performed. Histological examination revealed ureteral transitional cell carcinoma. He is now doing well at 6 months following the lat surgery, without any evidence of recurrence.     

A case of synchronous ipsilateral renal cell carcinoma and transitional cell carcinoma]

A case of synchronous ipsilateral renal cell carcinoma with renal pelvic and ureteral transitional cell carcinoma is reported. A 80-year-old man, who had had transurethral resection of bladder tumor three times, was admitted on August, 1989 for recurrence of bladder tumor. Excretory pyelography revealed a filling defect of left renal pelvis. Findings of retrograde pyelography and computed tomography were in accord with those of the excretory urograms. Under a diagnosis of the left renal pelvic and ureteral tumor associated with the bladder tumor, left nephroureterectomy with bladder cuff resection was performed. Pathological diagnosis was renal pelvic and ureteral transitional cell carcinoma with renal cell carcinoma, which existed incidentally in the same kidney. Double unrelated primary carcinoma in urinary tract, especially, double dissimilar primary carcinoma in the same kidney, is rare. To our knowledge, this case is the 20th double cancer in upper urinary tract reported in Japan.     

Simultaneous renal and transitional cell carcinomas in same kidney with subsequent lymph node metastasis: DNA flow cytometric study.

We report the DNA content in simultaneous renal and papillary transitional cell carcinomas in the same kidney with a subsequent metastasis of the transitional cell carcinoma to a left supraclavicular lymph node. The flow cytometric DNA analysis revealed aneuploid stemlines with identical DNA indices in both the transitional cell carcinoma and the metastatic lesion and a diploid pattern in the renal cell carcinoma. A discussion of these findings and the potential implication of DNA ploidy analysis in similar situations is presented.     

A case of synchronous ipsilateral renal cell carcinoma and ureteral transitional cell carcinoma

A 62-year-old man was admitted to our hospital with the chief complaint of right flank pain. Abdominal computed tomographic scan revealed a right hydronephrosis and intrapelvic tumor. Ultrasound revealed a renal mass lesion. Ultrasound guided renal biopsy and laparotomy of intrapelvic tumor was performed. The histopathological diagnosis was renal cell carcinoma and ureteral transitional cell carcinoma.     

A case of simultaneous contralateral renal cell carcinoma and ureteral transitional cell carcinoma

A case of simultaneous contralateral renal cell carcinoma and ureteral transitional cell carcinoma is presented. This patient underwent right radical nephrectomy, partial resection of left ureter and bladder, and end-to-end transureteroureterostomy. He is alive with no finding of recurrence after 1 year. Methods of treatment for bilateral urinary tract tumors are reviewed.     

Simultaneous, contralateral hypernephroma and renal transitional cell carcinoma

The second case of simultaneous, contralateral hypernephroma and renal transitional cell carcinoma is described. Methods of managing bilateral renal tumors are reviewed.     

A case of renal cell carcinoma in a horseshoe kidney: a case report

A case of renal call carcinoma associated with horseshoe kidney is reported. The patient was a 59-year-old woman complaining of right flank mass. Radiological examination showed right renal tumor and horseshoe kidney, and right nephrectomy was performed. Histological examination showed it to be clear cell type renal cell carcinoma. Only 17 cases of horseshoe kidney with renal cell carcinoma have been reported in Japan. We report the 18th case with a review of the literature.     

The postoperative irradiation of transitional cell carcinoma of the renal pelvis and ureter

The role of adjuvant irradiation in the treatment of transitional cell carcinoma of the renal pelvis and ureter was reviewed. Between June 1966 and March 1981, 41 patients underwent curative resections. A poor risk group was identified, with 23 patients demonstrating disease greater than grade 2 or stage B. Postoperative irradiation was administered to 11 of 23 patients. Median patient followup was 40 months. Two-thirds of all failures occurred within the first 12 months and no failure was seen beyond 35 months. Patients with poor prognostic features had a 60 per cent failure rate compared to 11.8 per cent of the patients with good risk factors (p equals 0.023). The median survival of the 2 groups was 28 and 99 months, respectively (p less than 0.001). Outcome of the poor risk patients was analyzed whether or not the patient received postoperative irradiation. None of the irradiated patients failed with local disease only, while there was 1 patient with local and distant recurrence. In contrast, the nonirradiated group had 5 local failures and twice the number of failures over-all. Median survival of the irradiated and nonirradiated patients was 35 and 26 months, respectively. The number of patients treated is too small to permit valid statistical conclusions and indicates the need for a multi-institutional study to determine if these suggestive findings of improved local control will be corroborated and translate into an improved survival rate.