偏头痛中医药治疗进展

偏头痛为常见的一种原发性头痛。因其发病年龄范围广,症状痛苦,病程时间长,已严重影响了人们的生活和工作。至今,偏头痛的发病原因可能与遗传、饮食、精神、内分泌等有关,而其发病机制尚不十分清楚。西药治疗偏头痛疗效肯定但存有较多副作用。偏头痛的病因复杂,临床上对不同类型偏头痛进行辨证治疗尤为重要。目前辨证客观化与证侯演变规律的研究尚不足,对辨证论治尚需要进行客观化、标准化、规范化的研究。     

偏头痛从肝风瘀论治的理论探析及临床应用

[目的]讨论偏头痛从肝风瘀论治的理论依据,并对其临床应用情况予以概述,为临床防治偏头痛提供指导思路。[方法]从病因病机学角度,结合偏头痛的发病特点,重点介绍偏头痛从肝、从风、从瘀论治的理论依据,并对临床常用的有效方剂的组成和临床疗效特点进行了总结。[结果]为临床从"肝、风、瘀"论治偏头痛提供了理论依据和部分代表方剂。[结论]偏头痛治疗多"从肝风瘀论治",疗效较佳,但关于偏头痛疗效评价标准的规范和现代机制的研究仍需要不断探索。     

针刺治疗偏头痛动物实验研究进展

偏头痛是临床常见的特发性头痛,针刺治疗偏头痛疗效确切,在临床上广泛使用。近年,学者们对针刺治疗偏头痛的作用机制进行了许多深入研究,取得了不少成绩。本文从对神经源性炎性反应的抑制、改善脑微循环、调节血管活性物质等方面综述了针刺治疗偏头痛的有关机制,并认为今后的研究可从针刺对电压门控离子通道的影响等方面开展。     

通心络胶囊对偏头痛患者CD62P的表达及脑电图的影响

目的探讨通心络胶囊对偏头痛患者血浆CD62P的影响及临床疗效。方法38例偏头痛患者作为治疗组,给予通心络胶囊,每次2粒,每天3次,治疗6周。治疗前后采用流式细胞仪检测血浆CD62P水平、并观察脑电图(EEG)变化。同时选择35名门诊健康体检者为对照组。结果治疗组治疗前血浆CD62P水平及EEG异常率明显高于对照组(P均<0.01);治疗后血浆CD62P水平及EEG异常率仍高于对照组(P均<0.05),但明显低于治疗前(P均<0.01)。结论通心络胶囊可以抑制偏头痛患者血小板活化功能的异常,并具有良好的偏头痛疗效。     

黄银兰分经辨证论治偏头痛的临床经验

黄银兰老师认为偏头痛针刺的治疗以经络辨证为核心,结合八纲辨证,具有较好的疗效,且其辨治思路清晰,处方少而精,便于临床应用,值得推广。     

头痛宁联合西比灵治疗偏头痛的疗效观察

偏头痛属于慢性神经性疾病,临床常见。本文主要通过对头痛宁联合西比灵治疗偏头痛、单纯头痛宁治疗偏头痛、单纯西比灵治疗偏头痛三组治疗效果对比分析,以探讨有效治疗方法。     

基于数据挖掘的针灸治疗偏头痛的选穴规律研究

目的探讨针灸治疗偏头痛的选穴特点及规律。方法计算机检索针灸治疗偏头痛的RCT文献,提取中医四诊信息,经过数据标准化处理并建立数据库,运用SPSS 20.0系统挖掘其选穴规律。结果共纳入文献94篇,其中涉及配穴方案48例。主穴取穴主要在头部,以胆经穴为多,通过系统聚类得到5组腧穴组合;配穴的选穴主在四肢,以脾经、胃经、肝经、胆经穴为多,通过系统聚类得到6组腧穴组合。结论针灸治疗偏头痛的主穴取穴注重局部取穴与辨经取穴的有机结合,而重在治痛;配穴取穴强调远部辨经、辨证取穴,而重在扶正祛邪。针灸治疗偏头痛的选穴重在培本祛邪,标本兼顾,为临床治疗提供依据和指导。     

古代与现代针灸治疗偏头痛思路之比较

本文以古今针灸对偏头痛的治疗思路为切入点,将古代、现代治疗思路进行详细比较,初步总结出了二者之间的相同点和不同点,并分成"古今相承"古遗今废"古无今创"3个部分分别予以说明,认为现代偏头痛的治疗思路、方法虽有所创新,但治疗思路仍较单一,并认为可以从偏头痛左右偏颇、少阳太阳并治等新的角度对该病进行临床研究与治疗。     

张树泉教授治疗偏头痛临床经验浅议

偏头痛是临床常见疾病,反复发作,严重影响患者生活质量。张树泉教授认为肝郁气滞,血瘀痰阻,上扰清窍,拘挛作痛是偏头痛基本病机,以行气活血,化痰开郁,柔筋缓急,通络止痛为基本治疗大法,在此基础上自拟通窍蠲痛汤加减治疗偏头痛多能取得较显著的疗效。     

Feverfew (Tanacetum parthenium) as a prophylactic treatment for migraine: a double-blind placebo-controlled study

To assess the effectiveness of feverfew as a prophylactic therapy for migraine, a double-blind placebo controlled cross-over trial was conducted for a period of 4 months. Fifty seven patients who attended an outpatient pain clinic were selected at random and divided into two groups. Both groups were treated with feverfew in the preliminary phase (phase 1), which lasted 2 months. In the second and third phases, which continued for an additional 2 months, a double-blind placebo-controlled cross-over study was conducted. The results showed that feverfew caused a significant reduction in pain intensity compared with the placebo treatment. Moreover, a profound reduction was recorded concerning the severity of the typical symptoms that are usually linked to migraine attacks, such as vomiting, nausea, sensitivity to noise and sensitivity to light. Transferring the feverfew-treated group to the placebo treatment resulted in an augmentation of the pain intensity as well as an increase in the severity of the linked symptoms. In contrast, shifting the placebo group to feverfew therapy resulted in a reduction of the pain intensity as well as in the severity of the linked symptoms. © 1997 John Wiley & Sons, Ltd.     

正天丸治疗偏头痛随机对照双盲双模拟多中心临床研究

目的 评价正天丸治疗偏头痛的临床有效性和安全性.方法 采用随机、双盲双模拟、阳性药平行对照的多中心临床研究方法.入选有效病例142例,其中试验组72例,口服正天丸及天麻头痛片模拟剂;对照组70例,口服天麻头痛片及正天丸模拟剂.两组疗程皆为60d,分别观察治疗前及治疗后偏头痛发作次数、头痛的强度、头痛发作的程度、持续时间、中医证候等指标的变化.结果 (1)试验组和对照组均能明显减少偏头痛发作次数,分别为(1.07±0.85)次和(1.51±1.04)次,P=0.117.(2)试验组和对照组能减轻偏头痛发作强度计分,分别为(2.18±1.47)分和(3.09±1.75)分,两组间比较差异有统计学意义(P＜0.05).(3)试验组和对照组均能缩短偏头痛发作持续时间,分别为(5.14±5.69)d和(6.64±6.47)d,P=0.113.(4)试验组和对照组能减轻偏头痛发作程度计分,分别为(6.39±3.08)分和(7.84±3.01)分,两组间比较差异有统计学意义(P＜0.05).结论 正天丸治疗偏头痛的临床疗效确切,无明显不良反应.     

针刺治疗偏头痛的神经影像学研究进展＊

偏头痛是一种以搏动性头痛为主要临床特征的神经系统疾病，极大地影响了患者的生活质量，有研究证实，针刺治疗偏头痛安全有效，但起效机制仍然不明确。研究针刺治疗偏头痛的机制，有助于推广针刺治疗偏头痛的适用。过去几年里，神经影像学的发展能够帮助人们深入的理解偏头痛的发病机制。同时，越来越多的针刺治疗偏头痛的神经影像机制研究促进了对针刺起效机制的理解。总的来说，24项针刺治疗偏头痛的神经影像学机制研究发现，针刺可以通过影响脑结构、脑代谢、以及脑功能起到治疗效果。因此，大脑功能结构的改变可能是针刺治疗偏头痛的中枢机制。在这个综述中，我们对当前偏头痛发病的神经影像学机制和针刺治疗的神经影像学机制进行了系统的整理，讨论了针刺治疗偏头痛神经影像学机制的发展方向与展望。     

中医体质与偏头痛相关性分析

目的:探讨中医体质与偏头痛的相关性.方法:选择2017年4月至2019年4月本院诊治的200例偏头痛患者为研究对象,入组为偏头痛组,同时选择200例在本院健康体检、无偏头痛的人群为对照组.对两组研究对象进行体质辨识,偏头痛组患者进行中医辨证分型,采用Logistic回归分析中医体质与偏头痛的相关性.结果:偏头痛组以女性...     

THERAPEUTIC CHARACTERISTICS AND RESEARCH PROGRESS OF ACUPUNCTURE ON MIGRAINE

Migraine is a common type of primary headache disorder.Patients suffer from a recurrent hours-lasting moderate to severe pain in a unilateral location.It brings great harm to patients' life quality.Epidemiological studies have shown that the lifetime prevalence of migraine is between 15% and 20% worldwide and about 8%to 13% in Asia.Currently, acupuncture is used in many countriesand has been proved as an effective therapy for migraine prophylaxis, that is, to reduce the frequency and number of migraine attack.The last Cochrane systematic review of acupuncture for migraine prophylaxis published in 2011 concluded that acupuncture was effective and possibly more effective than prophylactic drug treatment, with fewer adverse effects.There are some controversies about the effect of acupuncture in reducing the intensity of migraine.According to the primary results of our current studies about acupuncture as prophylaxis for migraine and menstrualrelated migraine, not only the frequency and time of attacked, but also the intensity of pain could be effectively improved.Furthermore, studies also demonstrated that acupuncture could reduce and even interrupt a migraine attack in prodrome period.For acupoint selection, we highlighted the importance of the methodology of syndrome differentiation on meridian theory.Syndrome differentiation based on theories of traditional Chinese medicine was a foundation for efficacy and necessary to be complied when trying to reduce the impacts of inducing factors of migraine by acupuncture treatment.     

小脑顶核电刺激治疗偏头痛40例

为观察小脑生物仪电刺激小脑顶核治疗偏头痛的疗效,将60例偏头痛患者随机分为治疗组40例(用小脑生物仪电刺激小脑顶核),对照组20例(服用镇脑宁胶囊),疗程均为3个月。结果:两组治疗皆有效,治疗组头痛积分下降幅度大于对照组(P<0.01);治疗组典型偏头痛积分下降幅度明显大于普通型偏头痛(P<0.01)。提示小脑生物仪治疗偏头痛有效,且对典型偏头痛疗效更佳。     

太极通天液对偏头痛病人血浆内皮素水平影响

目的 :探讨太极通天液对偏头痛病人血浆内皮素 ( ET)的影响。方法 :采用放射免疫法对 110例偏头痛病人口服太极通天液和安慰剂治疗前后血浆 ET进行测定 ,并观察其近期疗效。观察期为 4周。结果 :太极通天液可明显降低偏头痛病人血浆 ET水平 ( P <0 .0 1) ,其近期疗效优于安慰剂 ( P <0 .0 1)。结论 :太极通天液能降低偏头痛病人血浆 ET水平 ,是防治偏头痛的良药。     

Ginger (Zingiber officinale) in migraine headache

Migraine is considered as a neurological disorder with little convincing evidence of the involvement of some vascular phenomenon. Recent understanding of the mechanisms behind migraine pain generation and perception have considerably helped the development of modern migraine drugs. Most migraine drugs in use, i.e., ergotamine and dihydroergotamine, iprazochrome, pizotifen and diazepam; and non-steroidal antiinflammatory drugs (i.e. aspirin, paracetamol, persantin, etc.) have side-effects and are prescribed with caution for a limited duration. Ginger is reported in Ayurvedic and Tibb systems of medicine to be useful in neurological disorders. It is proposed that administration of ginger may exert abortive and prophylactic effects in migraine headache without any side-effects.     

通窍活血汤合方治疗偏头痛

偏头痛是临床中比较难治的疾病之一,因久病必瘀,偏头痛久病不愈多有瘀血,通窍活血汤是治疗血瘀头痛的古代名方,故以该方为主方治疗偏头痛。另外,偏头痛除血瘀外,常合并气滞、痰浊、寒凝、正虚等病机,所以临床合理运用通窍活血汤合柴胡疏肝散、半夏白术天麻汤、吴茱萸汤、四君子汤、四物汤、大补元煎等方辨治偏头痛,则能取得良好治疗效果。     

运用体质辨识理论开展偏头痛间歇期辨证施护的构想

偏头痛分为急性发作期和间歇期是疾病自身客观规律的体现。分期并特别重视间歇期的辨证施护是临床的需要,也是正确合理应用中医辨证的具体体现。根据偏头痛的发病特点和病理机制,在中医辨证理论的指导下筛选合适的专病专药、制定有别于偏头痛以外人群的体质干预即偏头痛间歇期中医药干预的具体措施十分必要。体质辨识在偏头痛间歇期中医辨证干预中的运用是体质辨识从普遍人群的干预到特殊疾病干预的积极尝试,运用体质辨识理论对偏头痛间歇期进行中医药干预无疑是对偏头痛的分期治疗提供了新的思路和方法。     

非药物疗法治疗慢性偏头痛的研究进展

慢性偏头痛是一种失能性神经系统疾病,全球发病率约2%。尚无可用的特效疗法,目前临床治疗主要以药物治疗为主,非药物治疗为辅。近年来,有关非药物疗法治疗慢性偏头痛的研究不断增加,部分非药物疗法在研究中显示出对慢性偏头痛治疗效应,文章对近期非药物疗法治疗慢性偏头痛的研究进行综述。