大腿部腺泡状软组织肉瘤1例报告

患者，男，２６岁。发现右大腿中部前外侧鸡旦大包块１年，进行性长大伴疼痛３个月入院。查体：右大腿中部前外侧有一椭圆形肿物，约１４ｃｍ×１１ｃｍ大，质中，活动度差，表面光滑，无明显触痛，与周围组织分界较清。彩色多谱勒超声显示为一混合性肿物，内含丰富的血管...     

腺泡状软组织肉瘤多发骨转移一例报告

腺泡状软组织肉瘤多发骨转移一例报告甄平刘兴炎文益民患者男，２７岁。以头昏伴双眼球进行性凸出、视物不清１５个月入院。全身四肢及躯干无疼痛及其他不适。查体：双额部骨性隆起，触之表面欠光滑，但未触及搏动。双眼球凸出，眼球各方向运动正常，无震颤。右侧第７肋骨...     

腺泡状肉瘤一例报告

患者男，６８岁。因右上臂疼痛月余，伤后功能受限１小时于１９９６年１１月２９日入院。Ｘ线片示：右肱骨中下段骨折，骨折远端可见２ｃｍ×１－５ｃｍ虫蚀样密度降低区，皮质变薄，无骨膜反应（图１）。诊断为骨囊肿并发病理性骨折。全麻下行骨囊肿刮除、植骨内固定术。术中见骨折远端皮质变薄、色黑，呈虫蚀状，髓腔内充满灰白色柔软组织，未见包膜；彻底刮除后，去除病变皮质，用质量分数为９５％酒精病灶灭活后植入髂骨，以两枚螺钉固定骨折。术后用管型石膏托外固定。病理检查见：致密纤维组织形成的不规则间隔内肿瘤细胞聚集成巢状实…     

腺泡状软组织肉瘤41例临床分析

本文综合国内报告的腺泡状软组织肉瘤４１例，以２５～３５岁中青年男性多见，四肢占６３．４％，尤以下肢多发，肿瘤生长慢，平均病程７年。单纯肿块切除２７例，平均２．５年内７例复发，１３例分别出现肺、脑、骨及十二指肠等转移，６例死亡，术后平均死亡时间１．５年；单纯切除术后化疗１例，于术后１．５年死于转移；单纯切除术后局部放疗１例，１１年后死于肺转移；７例截肢者有２例于１７年后死于肺、脑转移，５例生存；单纯切除加中药治疗２例，随访４年未见复发及转移。     

腺泡状软组织肉瘤22例临床治疗分析

目的探讨腺泡状软组织肉瘤的临床治疗和预后。方法对１９７３～１９９６年间收治的２２例腺泡状软组织肉瘤患者的临床资料进行回顾性分析。结果２２例均接受手术治疗,其中１７例行肿瘤局部切除,５例行扩大切除。７例病理误诊为其他软组织肿瘤（占３２％）。９例术后进行了预防性辅助放疗和（或）化疗。对２１例患者随访４个月至９年。６例患者术后复发（占２８％）,１３例出现肺转移（占６２％）,５例在随访８个月至４年５个月时死亡（占２４％）,６例患者生存５年以上。全组经ＫａｐｌａｎＭｅｉｒｅ生存率计算其３年、４年、５年生存率分别为８３％、７５％及６６％。结论腺泡状软组织肉瘤多需病理学诊断,肿瘤局部切除是复发和转移最重要的因素,术后预防性辅助治疗对局部复发和转移没有明显的控制作用,对出现肺转移的患者采取多程标准化疗方案进行治疗,临床效果尚满意     

肾腺泡状横纹肌肉瘤1例

患儿,男,7岁。入院前2个月有右腰部撞击伤史,当时无血尿、发热等,仅感右肾区持续性钝痛,伤后半个月曾间断出现过全程肉眼血尿2次,经B超及CT检查均提示右肾肿瘤并肾出血。体检:右肾区稍饱满,轻度叩击痛,可触及右肾下极,质较硬,表面1义马矿务局总医院外科(河南义马,472300)...     

前臂肌肉及全身骨组织多发腺泡状软组织肉瘤1例

腺泡状软组织肉瘤少见,好发于四肢深部肌肉,易发生转移.临床表现无特异性,术前大多误诊.本文报告1例,最先发生于前臂肌肉内,5年后发现颅骨及全身骨组织多发病变,病理证实为腺泡状软组织肉瘤.现报告如下.     

肾腺泡状横纹肌肉瘤一例报告

患儿,男,7岁,1995年9月29日以“右腰部撞伤伴疼痛2月,血尿一月余”为主诉收住院。入院前二月曾有右腰部撞击伤史,当时无血尿、发热等,仅感右肾区持续性纯痛。伤后半月曾间断出现过全程肉眼血尿两次。查体:轻度贫血貌,发育正常。右肾区稍饱满,轻度叩击痛,可触及右肾下极,质较硬,表面     

Primary alveolar soft-part sarcoma of stomach

A case of primary gastric alveolar soft-part sarcoma is presented. The tumor was found in the gastric remnant of a 67-year-old male who had undergone partial gastrectomy due to hemorrhagic gastric ulcer 13 years before. It was located mostly in the submucosa arising from the muscularis propria. The large eosinophilic cells showed the characteristic alveolar compartmentalization and contained intracytoplasmic periodic acid-Schiff-positive granules and typical crystals. Numerous electron-opaque secretory granules in the tumor cell cytoplasm, in addition to crystals of 9 nm periodicity, were confirmed at the ultrastructural levels. Immunostaining failed to detect muscle-related antigens. In contrast, methionine-enkephalin and neuropeptide Y appeared positive in the tumor cells. Interstitial spindle cells showed an occasional positivity to S-100. This is the first case of such a tumor occurring in the gastrointestinal tract, and the findings suggest that gastric alveolar soft-part sarcomas may have a different origin from those arising in the skeleton.     

Primary alveolar soft-part sarcoma of the liver: anomalous presentation of a rare disease

Alveolar soft-part sarcoma is a highly vascular soft-tissue tumor that is uniformly malignant. It comprises less than 1 per cent of all soft-tissue sarcomas. Patients with alveolar soft-part sarcoma most frequently are aged 15 to 35 years, and the soft tissues of the lower extremities typically are affected. In the pediatric population, it most frequently occurs in the head and neck and particularly affects the tongue and orbit. Alveolar soft-part sarcoma has been described as a primary lesion in the trunk, upper extremities, and retroperitoneum; more novel locations include the mediastinum, female genital tract, stomach, bone, and larynx. Numerous case reports describe alveolar soft-part sarcoma in diverse anatomic locations, but this report is, to our knowledge, the first documentation of primary alveolar soft-part sarcoma of the liver. We describe a 47-year-old woman with such a manifestation. Despite surgical resection and numerous chemotherapeutic regimens, this patient had widespread metastasis and died approximately 2 years after the diagnosis was established.     

Surgery for multiple lung metastases from alveolar soft-part sarcoma

Between 1985 and 1993, six patients were surgically treated for alveolar soft-part sarcoma (ASPS) arising from the thighs or buttocks, four of whom underwent aggressive excision of multiple metastases using a neodymium: yttriumaluminum garnet (Nd: YAG) laser. In total, 33 tumors were removed from these four patients during eight pulmonary operations. In patients, 1, 3, and 4, uncontrollable extrapulmonary involvement and/or local recurrence at the primary site were noted during their treatment course, and they died of tumor progression 40, 68, and 46 months after excision of the primary lesion, respectively. In patient 1, a 37-year-old woman, prolonged survival with adequate lung function was achieved after the excision of metastases, including one bulky metastatic tumor located adjacent to the mediastinum, which might have led to a lethal complication. Patient 3, a 25-year-old woman who underwent aggressive metastasectomies for both pulmonary and extrapulmonary metastases combined with intermittent chemotherapy, died of widespread metastases to multiple organs. On the other hand, patient 2, a 23-year-old woman who underwent excision of 130 pulmonary and three brain metastases during four thoracotomies and two craniotomies, is still alive without any symptoms 98 months after excision of the primary lesion. These data suggest that repeated excisions of lung metastases from ASPS may influence long-term survival or maintenance of good performance status in patients in whom extrapulmonary metastasis and recurrence are either absent or controlled.