Giant cell tumor of the larynx: a case report and review of the literature

Giant cell tumors are benign tumors commonly found in the long bones. Rarely, they may occur in the larynx, and patients with such tumors may present with hoarseness and anterior neck swelling. Since Wessely reported the first case of laryngeal giant cell tumor in 1940, 30 cases have been identified. Herein, we present a case of a 31-year-old man with giant cell tumor of the larynx successfully treated via the hemilaryngectomy approach.     

喉巨细胞瘤1例

患者,男,65岁。4个月前无明显诱因出现声嘶．无呼吸困难、吞咽、喉痛、咳血等不适,1周前突感呼吸不畅且进行性加重,吸气时明显,活动后加剧,夜间无法平卧,于2012年8月22日急诊入院。既往体健。否认其他疾病史。     

颈部骨外尤文氏肉瘤1例报道并文献复习

目的 探讨骨外尤文氏肉瘤(EES)的疾病特征,了解其临床表现、诊断及治疗方案.方法 对1例颈部EES患者的临床资料进行回顾性分析,复习相关文献并进行讨论.结果 该例EES患者临床表现及影像学特征缺乏特异性,确诊依赖于术后病检,其中免疫组化结果为PAS(+)、CD99(+)、Vimentin(+),基因检测EWSR1基因...     

Leiomyosarcoma of the larynx: case report and review of the literature

Leiomyosarcoma of the larynx is an extremely rare entity. This tumor is aggressive and is associated with dismal treatment results. We present a case of leiomyosarcoma of the larynx treated with surgery and postoperative radiotherapy. In this article we also discuss laryngeal leiomyosarcoma's clinical manifestations, associated diagnostic dilemmas, and optimal management, as well as a review of the literature.     

喉颗粒细胞瘤四例报告并文献复习

正颗粒细胞瘤(granular cell tumor,GCT)临床上较为少见,发生于喉部的更为罕见。2011年4月至2017年5月,青岛大学附属医院耳鼻咽喉头颈外科共收治喉颗粒细胞瘤4例,其中成人2例,儿童2例,现报告如下。1临床病例例1,男,41岁,因"声音嘶哑3年余"于2011年4月27日入院,检查:右侧声带中份可见息肉样肿物,表面光滑,声带活动可,闭合欠佳。电子喉镜检     

Giant lipoma of the larynx: a case report and literature review

Fewer than 15% of lipomas occur in the head and neck. To date, fewer than 100 cases of laryngeal lipoma have been reported in the literature. Typical clinical manifestations include dysphagia, dyspnea and hoarseness, as well as the presence of a smooth or pedunculated mass seen endoscopically and a low attenuation mass on computed tomography scan. Pathologic sections commonly reveal a tumor consisting of mature adipocytes, which is often encapsulated. Treatment of laryngeal lipoma varies from conservative total endoscopic removal to external surgical approaches. The following is a report of a single case of laryngeal lipoma, including pathologic and radiologic findings, as well as a review of the literature.     

Giant cell tumor of the masticator space: case report and literature review

Giant cell tumors of the head and neck are rare. We describe the case of a 50-year-old man who presented with otalgia and eustachian tube dysfunction. After his symptoms persisted despite aggressive medical management, further investigation revealed the presence of a firmness in his left parotid tail. Computed tomography identified a heterogeneously enhancing mass in the left masticator space. The tumor was removed surgically, and it was diagnosed on histopathology as a giant cell tumor. The patient recovered uneventfully and was closely followed for signs of recurrence. To the best of our knowledge, ours is the first reported case of a giant cell tumor in the masticator space. We review the literature on giant cell tumors of the head and neck, with particular attention given to cases involving the temporomandibular joint.     

Granular cell tumor of the parotid: a case report and literature review

Granular cell tumors are relatively uncommon soft tissue lesions that originate in Schwann's cells. Although these tumors can occur at any site, their presence in the parotid gland is very unusual. This article describes one such case in a 48-year-old woman, followed by a brief review of the literature on this subject.     

Mycosis fungoides of the larynx: case report and review of the literature

Mycosis fungoides is a rare cutaneous lymphoma. Dissemination to extra-cutaneous sites occurs at advanced stages of disease. Laryngeal manifestations of mycosis fungoides have been reported in only 13 cases in the available literature. We present a further calla of mycosis fungoides of the larynx at the terminal stage of disease with an additional manifestation in the left maxillary sinus and review the cases published to date. To our knowledge this is the first reported case of mycosis fungoides with laryngeal and paranasal sinus manifestation. Concluding from the present case and from literature therapy should be palliative to improve quality of life.     

Plasma cell granuloma of the larynx (case report and review of the literature)

A case is reported of Plasma Cell Granuloma of the larynx treated successfully with steroids and antibiotics.     

Rhabdomyosarcoma of the larynx: A case report and review of the literature

Rhabdomyosarcoma is rarely diagnosed in the larynx. A case report and five patients from the Otolaryngic Pathologic Files of the Armed Forces Institute of Pathology are added to the world literature. Current modes of treating Stage III rhabdomyosarcomas are reviewed. The recent literature suggests that certain of these neoplasms may be treated successfully without radical surgery.     

Primary malignant melanoma of the larynx: a case report and literature review

A 56-year-old Japanese man presented with hoarseness and left sided neck swelling in June 2003. Endoscopy showed an irregular tumor extending from the anterior commissure to the left ventricle with dark pigmentation. A biopsy showed malignant melanoma. A total laryngectomy with left radical neck dissection was performed in July 2003, followed by chemohormonal therapy and radiotherapy to the neck. Multiple bone metastases were diagnosed in May 2004, and the patient died with disseminated disease in April 2005, 21 months after initial treatment. The medical literature on laryngeal malignant melanoma was reviewed, and suggested a very poor prognosis despite therapy with surgery, radiotherapy, and chemotherapy.     

喉纤维上皮性息肉1例并文献复习

目的 探讨喉纤维上皮性息肉（FEP）病因、临床特征、诊断、鉴别诊断,提高对头颈部FEP的认识。方法 回顾性分析1例原发于喉的FEP患者的临床资料,结合文献复习总结FEP的临床诊断治疗经验。该患者先行气管切开解除气道梗阻并行喉肿物活检,病理示FEP后再次支撑喉镜下等离子行喉FEP完整切除。结果 患者术后恢复好,成功拔除气套管,随访1年未见复发及恶变。结论 喉FEP为来源于中胚层的良性肿瘤,临床罕见,治疗以手术完整切除为主,预后良好,不易恶变。     

Malignant lymphoma of the larynx: a case report and review of the literature

BACKGROUND: Malignant lymphoma of the larynx are rare tumors and represent less than 1% of primary malignant laryngeal tumors. CASE REPORT: In this case report we present a case of a diffuse large B-cell lymphoma of the larynx. Clinical presentation, diagnostic approach, staging and differential diagnosis as well as therapy and prognosis are discussed in relation to the available literature. CONCLUSIONS: Lymphomas primary to the larynx are non-Hodgkin-lymphomas and are predominantly located in the supraglottic larynx. The presenting symptoms and signs include dysphagia, dysphonia, dyspnea which on occasion can be severe, and enlarged cervical lymphoma. B-symptoms are mostly not present. Indirect laryngoscopy reveals a globoid submucosal faintly pink tumor mass. The diagnosis rests on histological examination of a biopsy specimen. Benign tumors, squamous cell carcinoma and other lymphoproliferative diseases have to be excluded from the differential diagnosis. Extensive tumor staging is necessary before radiotherapy or chemotherapy. Surgery is not indicated, even in localized disease. Prognosis is good in the most often localized laryngeal non-Hodgkin-lymphomas (stage IE and IIE) and generalization is rare. Hence, supraglottic submucosal laryngeal tumors can represent non-Hodgkin-lymphomas. Biopsy and subsequent histological examination are essential for correct diagnosis.     

Recurrent well-differentiated liposarcoma of the larynx: a case report and review of literature

We present a rare case of recurrent well-differentiated liposarcoma, which re-occurred 26 years after initial presentation, having presented non-acutely on both occasions with dyspnoea, progressive dysphonia and intermittent stridor due to a valve-like laryngeal obstruction happening mainly when supine. We have discussed management of these recurrent well-differentiated liposarcomas of the larynx including the adequacy of local versus radical treatment with review of literature which reveals that only nine cases have been reported so far.