A case of primary extracranial meningioma of the forearm with bone invasion

We report here a rare case of primary extracranial meningioma in a 73-year-old woman with an asymptomatic mass located in the left distal-dorsal forearm. MRI revealed the lesion to be poorly circumscribed and unclear, with iso-signal intensity to muscle on T1 and with a relatively high signal intensity on T2-weighted imaging. The histopathology of the specimen from incision biopsy was typical of meningioma, showing bland spindle cell proliferation with a whorling pattern. Immunohistochemically, the tumor cells were positive for epithelial membrane antigen and vimentin, and negative for S-100 expression.     

Synovial sarcoma of primary bone origin: a rare case in a rare site with atypical features

Synovial sarcoma of bone origin is extremely rare and difficult to diagnose. We present a case in which the lesion arose in the cortex of the distal tibia. It showed heterogeneous intermediate signal intensity on T1-weighted images and heterogeneous intermediate to low signal intensity on T2-weighted images with heterogeneous contrast enhancement on MRI. The lesion was confirmed as synovial sarcoma using a combination of histological and molecular genetic studies.     

非典型脑膜瘤的MRI诊断

目的:分析非典型脑膜瘤的MRI表现及病理基础,以提高对该肿瘤的认识.方法:回顾性分析经手术病理证实的15例非典型脑膜瘤的MRI表现,探讨肿瘤的部位、形态、有无出血囊变、瘤体占位效应、瘤周水肿、瘤体信号及强化特点,并行病理对照分析.结果:本组15例非典型脑膜瘤,部位典型者13例(86.7%),典型部位以大脑镰、矢状窦旁、...     

非典型性脑膜瘤的MRI表现

目的：分析非典型性脑膜瘤MRI征象及其预后。方法：回顾性分析经手病理证实为非典型性脑膜瘤共20例;探究其预后情况。结果：20例非典型性脑膜瘤中17例部位均较典型,不典型部位在侧脑室三角区、视神经各1例,多发者1例。病灶呈类圆形或半圆形,略呈分叶状状,信号多表现不均匀,其中出血者2例,明显囊变者3例,瘤周不同程度水肿,有脑膜尾征15例,表现为均匀线状或粗细不一。4例骨质改变,术后残留或复发6例。20例术前MRI诊断为脑膜瘤者18例,误诊2例,误诊率为10%。结论：非典型性脑膜瘤的MRI表现有一定特征性,具有一定的侵袭性;充分认识非典型性脑膜瘤的MRI特点及肿瘤与邻近结构的关系,对肿瘤的定性以及制定手术方案有重要的指导作用。     

A congenital long rectoscrotal fistula: A rare variant

Congenital rectoscrotal fistula is a rare variant of anorectal malformations (ARM) as per pena classification. Its nomenclature as well as the management, obviously has not been discussed in literature so far. One such rare case and its management in a male neonate have been discussed here. Non or occasionally deflating congenital recto scrotal fistula has to be managed like an intermediate ARM.     

不典型脑膜瘤MRI误诊分析

本文收集了经组织病理证实的脑膜瘤14例,术前MRI均误诊为其他肿瘤,分析其误诊原因,以提高不典型脑膜瘤的MRI诊断的准确性。1材料与方法1.1一般资料收集经手术病理证实的术前误诊病例14例,男性9例,女性5例,年龄12~73岁。均行MRI检查,并行MRI增强。临床症状依据肿瘤生长部位不同而表现不同,包括头痛,头晕,神经麻痹等。病程1月~2年不等。     

A rare developmental variant of the atlas

Congenital anomalies of the arch of the atlas in the sense of clefts are uncommon. As such anomalies may be mistaken for fractures, radiologists should be aware of them. A case of aplasia of the right part of the posterior arch producing wide, asymmetric medial cleft of the atlas is presented. The patient also had hypoplastic left part of the arch with the lateral cleft formed by a secondary ossification centre in the posterior tubercle. This combination of anomalies has not formerly been presented in literature.     

A rare cause of pulmonary metastasis: benign metastazing leiomyoma

The authors report a rare cause of pulmonary metastasis of a benign tumor, uterine leiomyoma, observed in a black African woman. Plain chest radiograph showed multiple pulmonary nodules. These features were confirmed at CT. Transbronchial and surgical lung biopsies were consistent with pulmonary metastases from benign uterine leiomyoma. Hormonal treatment was instituted and resulted in regression of nearly all lesions at one year. Benign metastazing leiomyoma is a rare condition, in spite of the high rate of uterine leiomyoma in black African women.     

Crossed doubled patellar tendon: A rare anatomical variant with potential clinical significance

The patellar tendon is an integral part of the knee extensor mechanism and has been historically described as a single tendon. A doubled patellar tendon is an exceedingly rare finding. We present a case of a crossed doubled patellar tendon in a 70-year-old male with a history of right knee pain, which to our knowledge has only been reported once before in the literature. The presence of a doubled patellar tendon has a potential influence on surgical planning and in the etiology of anterior knee pain.     

A rare case of multifocal atypical teratoid rhabdoid tumor

Atypical rhabdoid teratoid tumor of the primary central nervous system is an uncommon and highly aggressive tumor that often affects infants and young children. Approximately two-thirds of tumors start in the posterior fossa. The best treatment for atypical rhabdoid teratoid tumor is yet unknown. Chemotherapy, radiation, and surgery are available as treatment options. Their respective roles are yet not each well defined. The prognosis for atypical rhabdoid teratoid tumor is absolutely poor. In this article, we intended to introduce a very rare case of multifocal atypical rhabdoid teratoid tumor in a 7-year-old boy.     

对比分析血管瘤型脑膜瘤与非典型脑膜瘤的MRI征象

目的 对比分析血管瘤型脑膜瘤与非典型脑膜瘤的MRI征象,提高鉴别诊断能力.方法 回顾性分析经手术病理证实的21例血管瘤型脑膜瘤与37例非典型脑膜瘤的MRI资料,比较2种脑膜瘤的MRI征象,并进行统计学分析.结果 血管瘤型脑膜瘤与非典型脑膜瘤相比,肿瘤分叶征(x2 =5.754,P=0.022)、脑膜尾征形态(x2=13.107,P=0.000)及长度(t=2.123,P=0.038)、瘤脑界面(x2=20.292,P=0.000)、邻近骨质改变(x2=4.321,P=0.044)及肿瘤强化程度(x2=8.846,P=0.005)6项差异均有统计学意义.瘤脑界面(x2 =9.761,P=0.002),邻近骨质改变(x2=9.547,P=0.002)2项联合对于2类脑膜瘤的鉴别有显著的影响(P均＜0.05).肿瘤的囊变坏死(x2=0.003,P=1.000)、瘤内血管流空信号(x2=0.823,P=0.506)、瘤周水肿(x2=0.222,P=0.640)及肿瘤强化后均匀性(x2 =0.000,P=1.000)4项差异无统计学意义(P均＞0.05).结论 血管瘤型脑膜瘤与非典型脑膜瘤在肿瘤分叶征、脑膜尾征长度、瘤脑界面、邻近骨质改变及肿瘤强化程度的MRI征象存在差异,有助于两者鉴别.     

Hemangioma of the maxillary sinus: A benign and rare cause of epistaxis

Hemangioma of the facial sinuses is a rare pathology, and given the lack of clinical specificity, the differential diagnosis with a malignant lesion often arises. We report the case of a 32-year-old patient who consulted for recurrent epistaxis of moderate severity. The preoperative diagnosis of a hemangioma of the left maxillary sinus was based on computed tomography and magnetic resonance imaging data, confirmed by the anatomopathological study of the surgical specimen, preceded by an embolization that facilitated the endoscopic surgical excision.     

Granular-cell tumor: a rare variant of mammary tumor

BACKGROUND: Granular cell tumor (GCT) is a rare variant of mammary tumor beset with diagnostic dilemmas that may be resolved by using numerous, very complex, enzymohistochemical and immunohistochemical methods. CASE REPORTS: We reported three female patients 16, 21 and 65 years old, operated on for mammary tumor at the Surgical Clinic of the School of Medicine in Nis, over the period of thirty years, 1977 to 2007. During this period 14.022 mammary tumors were diagnosed, including these three cases. These tumors had benign characteristics, without associated tumors in other localizations. A typical histological feature of GCT was a granular cytoplasm in large ovoid cells, organized like nests or like a trabecular arrangement. The tumors were analyzed by sets of histochemical, enzymohistochemical, immunohistochemical methods as well as ultrastructural examination. Protein, S-100 neuron-specific enolase and vimentin expressed a diffuse and intensive immunohistochemical activity, while expression of estrogen and progesterone receptors, as well as HER-2 oncoprotein was negative. The ultrastructural analysis confirmed that the tumor cells were enriched by lysosomes and consequential disorganization of cytoplasm. CONCLUSION: The reported enzymo- and immunohistochemical combined methods provide a precise diagnosis and confirm the GCT's neural origin, which has been disputed for years.     

Dural congestion accompanying meningioma invasion into vessels: the dural tail sign

Our purpose was to verify the histological appearance of the dural tail accompanying meningiomas on MRI. We studied seven patients such a dural tale. We examined the point of attachment of the tumour and the adjacent dura mater histologically. In all patients, rich vascularity and dilated vessels were observed in the dura mater at the point of attachment of the tumour; tumour cells invaded the dura mater and vessels, packing the latter. In the adjacent dura mater, showing as a dural tail on MRI, there was tumour-cell invasion in only one patient. Vascular congestion around the vessels compacted by the tumour cells in the dura mater and dilated vessels were seen in all patients. We therefore suggest that the mechanism of the dural tail sign is as follows. First, tumour cells invade vessels and pack them at the point of tumour attachment. Then, vessel congestion is induced in the adjacent dura mater, as a result of which it enhances markedly, giving rise to the dural tail sign. Received: 31 July 2000 Accepted: 29 September 2000     

Calcitonin treatment in hereditary bone dysplasia with hyperphosphatasemia: a radiographic and histologic study of bone.

Two children with bone dysplasia with hyperphosphatasemia (juvenile Paget's disease) were treated with synthetic human calcitonin. The progress of bone disease was monitored radiographically and histologically. Pretreatment radiographs showed markedly abnormal bone, characterized by lack of discrete cortex and absence of normal modeling. During treatment a discrete cortex was formed composed of compact bone, and more normal modeling occurred. This coincided with a histologic change from woven bone before treatment to a more lamellar type during treatment.