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1.
目的:研究进展期胃窦癌No.14v组淋巴结的转移规律。方法:通过对50例进展期胃窦癌患者行D2根治术,检测No.14v组淋巴结转移情况、No.6淋巴结转移情况、肿瘤浸润深度、肿瘤TNM分期、肿瘤直径及肿瘤分化程度,然后统计分析No.14v组淋巴结转移与上述其他检测指标之间的关系及术前CT检查的准确率。结果:术前CT检查发现No.14v组淋巴结转移阳性率为2%,假阴性率为12%。进展期胃窦癌No.14v组淋巴结转移率为12%。No.6淋巴结转移阳性者No.14v组淋巴结转移率24%,No.6淋巴结转移阴性者No.14v组淋巴结转移率3%。No.14v组淋巴结转移与No.6淋巴结转移、肿浸润深度、肿瘤TNM分期及肿瘤直径有关妒〈0.05),而与肿瘤分化程度无关(P〉0.05)。结论:CT对No.14v组淋巴结转移的诊断准确性不高,进展期胃窦癌No.14v组淋巴结转移率较高,No.6淋巴结转移阳性者No.14v组淋巴结转移率高。  相似文献   

2.
Neck dissection has a therapeutical as well as a prognostic relevance with respect to regional recurrence and distant metastases. Between January 1973 and July 1986 576 neck dissections in 511 patients (396 men, 115 women, among whom 486 with squamous cell carcinoma of the head and neck, and 14 with neck metastases of an unknown primary tumour) were performed at the department of Otolaryngology-Head and Neck Surgery of the Free University Hospital, Amsterdam. Patients with tumour at the margins were excluded. Recurrence-free curves were calculated according to Kaplan-Meier and the log rank test was used to test the differences. All patients underwent a comprehensive neck dissection and were irradiated postoperatively when three or more tumour-positive nodes or extranodal spread were reported by the pathologist. Endpoint for analysis was occurrence of an ipsilateral neck recurrence or of a distant metastasis. Figures were corrected for a simultaneous recurrence at a higher level. A total of 29 neck recurrences (7.2%; n = 523) and 26 distant metastases (10.7%; n = 281) were demonstrated in the 5-year follow-up period. The number of positive nodes was of prognostic significance for both events (p = 0.039 and p = 0.0027). Extranodal spread was shown only to increase the incidence of distant metastases (p = 0.017), whereas its prognostic value with regard to recurrence in the neck was nullified by the strict institution of postoperative radiotherapy. It is recommended to give radiotherapy to patients with two positive nodes and possibly to every patient with a histopathologically positive neck.(ABSTRACT TRUNCATED AT 250 WORDS)  相似文献   

3.
Clinical and pathological features of perineural spread have been investigated in patients with squamous carcinomas at several sites in the head and neck. In 100 surgical cases, the clinical and pathological findings were congruent in 76%. Combined clinical and histological evidence of perineural invasion was recorded in 33% and the overall incidence of nerve involvement detected morphologically was 44%. Perineural infiltration was demonstrated histologically in 51% of major excisions from the buccal cavity and in 34% of resections from the oropharynx, hypopharynx and cervical oesophagus. The neurological findings were dominated by hypoaesthesia, dysaesthesia and referred pain – mainly in the territories of cranial nerves V and IX. Multiple and/or sequential nerve involvement was occasionally seen. No correlation was established between nerve invasion and metastasis to regional lymph nodes. Long-distance infiltration of nerve trunks, and multiple involvement, are grave prognostic features.

In 17 terminal patients submitted to autopsy, 65% had combined clinical and pathological evidence of perineural spread and the overall incidence of nerve involvement detected morphologically was 88%. Sensory changes again predominated. Multiple nerve involvement was observed in 35%. An apparently new `dysphagia syndrome' is described in 4 patients with oropharyngeal carcinomas in whom gross mechanical obstruction was simulated by a combination of perineural spread of tumour into the ipsilateral vagal trunk, sometimes accompanied by segmental infarction, variable invasion of the sympathetic chain, and `splinting' of the pharynx by local fibrosis and tumour in the soft tissues of the neck. Short-term palliation was achieved in these patients with high-dose steroids.

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4.
余慧敏  易村犍 《中国妇幼保健》2011,26(20):3070-3072
目的:探讨宫颈癌ⅠB~ⅡB期淋巴结转移的高危险因素以及转移途径,了解盆腔淋巴结的转移规律,为选择性淋巴结切除提供一定的依据。方法:对湖北省荆州市第一人民医院2000年1月~2007年10月的子宫颈癌ⅠB~ⅡB期291例住院手术患者的临床病理资料进行回顾性分析。结果:在291例患者中,盆腔淋巴结转移64例,淋巴结转移率为22.0%。转移部位以闭孔最多,占18.2%(53/291),其余依次为髂内4.8%(14/291)、髂总3.4%(10/291)、髂外3.1%(9/291)、腹股沟深淋巴结1.7%(5/291),宫旁淋巴结0.7%(2/291)。淋巴结转移与临床分期、间质浸润深度相关,而患者组织学病理分级、年龄、肿瘤大小、组织学类型与淋巴结转移无关。结论:闭孔淋巴结是子宫颈癌最常见转移部位,可能是宫颈癌的前哨淋巴结。宫颈癌患者的临床分期、间质浸润深度是影响宫颈癌盆腔淋巴结转移的重要因素,而对宫颈癌患者进行手术治疗时应充分考虑这些高危因素。  相似文献   

5.
目的 探讨利用Ⅵ区淋巴结转移状态预测颈部淋巴结阴性(cN0期)甲状腺乳头状癌侧颈淋巴结转移的可行性.方法 回顾性分析2003年1月至201 1年10月接受同侧预防性颈部淋巴结清扫(Ⅱ~Ⅴ区或Ⅱ~Ⅳ区)的73例cN0期甲状腺乳头状癌患者的临床资料,分析Ⅵ区淋巴结转移与侧颈淋巴结转移的相关性.结果 73例cN0期甲状腺乳头状癌患者中,侧颈淋巴结转移率为16.4%(12n3),Ⅵ区淋巴结转移率为42.5%(31/73),多因素分析显示Ⅵ区淋巴结转移是影响cN0期甲状腺乳头状癌侧颈淋巴结转移的独立危险因素(OR=7.3,P=0.020).结论 Ⅵ区淋巴结转移状态用于预测cN0期甲状腺乳头状癌侧颈淋巴结转移是可行的.  相似文献   

6.
目的探讨乳腺肉瘤的临床特点和治疗方法。方法回顾性分析1972年1月~2006年9月收治的28例乳腺肉瘤患者的临床资料。结果术后随访10个月至32年,1例失访,随访率为96%。6例死亡,7例复发。5年生存率为80.3%,10年生存率为71.0%。结论乳腺肉瘤的治疗方法以手术治疗为主。对于肿块较小,无淋巴结转移的患者可行单纯乳腺切除术;对于有腋窝淋巴结转移的患者需行乳腺癌根治术。对局部复发的患者不应放弃再次手术的机会。  相似文献   

7.
OBJECTIVE: To determine in patients with mammary carcinoma and a sentinel node metastasis whether pathological parameters of the sentinel node metastasis and the primary tumour might have predictive value with respect to the presence of metastases in other axillary nodes. DESIGN: Prospective. METHOD: The study group consisted of the first 100 consecutive patients with a sentinel node metastasis, who subsequently underwent a complete axillary dissection. The patients with metastases in the non-sentinel nodes were compared to those without such metastases regarding the size of the largest sentinel node metastasis and the presence of extranodal tissue invasion near any such node, and size, and type of the primary tumour. RESULTS: The median size of the metastases in the sentinel lymph node in the two groups was 3 mm versus 13 mm respectively (p < 0.001) and the frequency of extranodal tissue invasion 3% versus 74% respectively (p < 0.001); the combination of these factors strongly predicted the presence of non-sentinel lymph node metastases in the axilla (94% area under the receiver operating characteristics curve). None of the 30 patients with a micrometastasis < or = 2.0 mm in the sentinel lymph node had metastases in the non-sentinel axillary lymph nodes. Metastases were present in the non-sentinel axillary lymph nodes in 29 of the 31 patients with extranodal tissue invasion near the sentinel node. CONCLUSION: In breast cancer patients with a sentinel lymph node metastasis < or = 2.0 mm and without extranodal tumour growth a complete axillary lymph node dissection might be unnecessary as the risk of additional metastases was very small.  相似文献   

8.
目的 探究正电子发射计算机断层显像(PET-CT)对肺癌纵隔淋巴结转移的诊断效能,分析影响诊断效能的相关因素以及肺癌淋巴结转移的影响因素,为临床提供理论参考。方法 选取我院2019年1月—2020年12月收治的经手术病理证实的181例肺癌(476枚淋巴结)患者临床资料进行分析,均行PET-CT进行诊断,分析诊断的效能(灵敏度、特异性、准确性以及阳性/阴性预测值);分析影响PET-CT诊断效能的因素,以及肺癌患者发生纵隔淋巴结转移的相关危险因素。结果 PET-CT诊断肺癌淋巴结转移的灵敏度65.75%(96/146),特异性89.39%(295/330),准确率82.14%(391/476),阳性预测值73.28%(96/131),阴性预测值85.51%(295/345),同手术病理结果相比,差异无统计学意义(P > 0.05)。真阳性淋巴结与假阳性淋巴结的短径、SUVmax值相比较,差异均无统计学意义(P > 0.05);真阳性淋巴结与假阳性淋巴结的密度相比,差异有统计学意义(P < 0.05)。经Logistic回模型分析分析显示,肿瘤的病理类型为腺癌、中央型肺癌、低分化程度是肺癌患者发生纵隔淋巴结转移的危险因素(P < 0.05)。结论 PET-CT诊断肺癌纵隔淋巴结转移有较高的灵敏度、特异性、准确性;诊断的灵敏度受淋巴结的短径与SUVmax值影响,诊断的特异性受淋巴结的密度影响。纵隔淋巴结转移主要与病理类型、病灶部位、分化程度有关。  相似文献   

9.
Mediastinoscopy and CT are used to evaluate the mediastinum in patients with non small cell lung cancer to determine operability. Generally, the sensitivity and negative predictive value of CT are high, in a personal study in 150 patients 86% and 92%, respectively. When CT does not reveal enlarged lymph nodes, we recommend thoracotomy without mediastinoscopy. However, micrometastases in non-enlarged lymph nodes will be missed. All positive CT scans necessitate mediastinoscopy, because enlarged lymph nodes frequently are not invaded with tumour (in our study in 33%). CT used in this way will increase the percentage of positive results of mediastinoscopy. In patients with a peripheral tumour lymphogenic spread to the mediastinum is not uncommon (in our study in 22%) and mediastinal evaluation should not be omitted. In these patients mediastinoscopy is also of diagnostic value.  相似文献   

10.
目的研究术前彩超在诊断分化型甲状腺癌早期颈转移中的作用。方法将潼南县人民医院80例患者随机分为研究组和对照组两组,其中研究组患者为术前颈部触诊为阴性,由彩超检查诊断为甲状腺癌颈转移的32(35侧)例患者,对照组为术前颈部触诊为阳性,诊断为甲状腺癌颈转移的48(50侧)例患者,两组患者都受过改良型颈清扫术,同时比较两组患者术前和术后的病理情况。结果由彩超诊断为颈转移的32例患者中,术后病理有25侧为颈转移,彩超检查的灵敏度为89%。并且彩超发现有66%的转移淋巴结为多分区转移,其中中颈为最高。病理发现有76%的转移淋巴结为多分区转移,通过研究发现病理和彩超的检查结果基本相同。结论术前彩超可以提高诊断分化型甲状腺癌早期颈转移的诊断率,并且对转移淋巴结进行准确定位。  相似文献   

11.
目的 比较胸部计算机断层扫描(computer tomography,CT)和磁共振成像(magnetic resonance imaging,MRI)判断胸段食管癌淋巴结转移的临床价值。方法 回顾性分析2015年7月—2019年6月在我院诊治的胸段食管癌淋巴结转移患者90例,所有患者在入院后均采用胸部CT和MRI平扫及增强扫描,并在手术后对病灶组织标本进行病理学检测,以病理诊断结果为金标准,分析胸部CT和MRI灵敏度和特异度。结果 MRI扫描,灵敏度为88.73%,特异度为94.74%,阳性预测值为98.44%,阴性预测值为69.23%,高于胸部CT扫描的69.01%、52.63%、84.48%、31.25%。淋巴结转移分布中,胸中段最多,胸上段、胸中段、胸下段所占比例分别为26.67%、60.00%、13.33%,胸上段中最上纵隔和气管旁淋巴结转移最多,胸中段气管旁、隆突下淋巴结转移最多,胸下段贲门旁、胃左动脉旁淋巴结转移最多,MRI诊断准确率高于胸部CT。结论 胸部CT、MRI均能够诊断出胸段食管癌淋巴结转移,MRI诊断胸段食管癌淋巴结转移的诊断价值优于胸部CT,MRI在胸段淋巴结各部位的诊断准确率高于胸部CT,能够更清晰显示淋巴结的转移情况。  相似文献   

12.
目的探讨原发性肺癌胸内淋巴结转移规律及方式,为确定肺癌术中淋巴结清扫范围提供依据。方法按Naruke肺癌淋巴结分布图作为淋巴结清扫依据,对85例肺癌行完全性切除及广泛肺门、叶间及同侧纵隔淋巴结清扫术。结果85例肺癌共清除淋巴结874枚。总转移率为58.8%(50/85),N1占21.2%(18/85),N2占37.6%(32/85),跳跃性N2共9.4%(8/85)。分布在纵隔第1、2、4、5、6、7组淋巴结。结论淋巴结转移与肺癌大小、部位、病理类型有关。肺癌淋巴结转移具有多组别、多区域及跳跃性,肺癌早期淋巴转移在T1期,所以,肺癌术中有必要常规胸内淋巴结清扫。  相似文献   

13.
李莉芳 《中国妇幼保健》2008,23(13):1771-1773
目的:探讨Ⅰ期子宫内膜癌生物学行为和相关因素。方法:对该院1997年1月~2006年12月收治的167例Ⅰ期子宫内膜癌患者临床资料进行回顾性分析。结果:临床Ⅰ期盆腔淋巴结转移率为11.3%;术前分段诊刮加B超检查,对判断浸润深度有一定价值,但与术后病理检查相比,差别有显著性意义(P<0.01)。经单因素分析:浸润深度、病理分级和组织学类型均与盆腔淋巴结转移有关(P<0.05)。结论:分段诊刮加B超检查对判断浸润深度有一定价值,但需提高精确度。Ⅰ期子宫内膜癌盆腔淋巴结转移与子宫肌层浸润深度、组织学类型和病理分级密切相关。临床Ⅰ期低危组可仅行全子宫双附件切除,不必盆腔淋巴结清扫。  相似文献   

14.
目的 探讨中央区淋巴结清扫术在临床颈侧淋巴结阴性甲状腺乳头状微小癌(PTMC)中的意义.方法 回顾性分析72例临床颈侧淋巴结阴性PTMC患者的临床资料,患者均行患侧甲状腺、峡部切除及对侧甲状腺腺叶次全切术+中央区淋巴结清扫术,术后长期随访.结果 24例出现中央区淋巴结转移,48例未出现中央区淋巴结转移,随访1.5~4.5(3.4±1.1)年,4例患者出现喉返神经麻痹,均在4个月内恢复正常.4例患者术后第3年发现颈部淋巴结转移,余患者均未见转移.结论 临床颈侧淋巴结阴性PTMC患者易出现中央区淋巴结转移,行中央区淋巴结清扫术对临床颈侧淋巴结阴性PTMC有较重要的应用价值,可降低并发症、改善患者预后.  相似文献   

15.
目的 探讨机器人辅助腹腔镜改良腹膜后淋巴结清扫术在治疗肾盂和上段输尿管肿瘤患者中的手术技巧,总结短期疗效。方法 回顾性分析2019年1月至2022年1月由南京医科大学第一附属医院收治的22例高危肾盂和(或)上段输尿管肿瘤患者的临床资料,患者均接受机器人辅助腹腔镜肾盂癌根治术+改良腹膜后淋巴结清扫术治疗。左侧清扫范围包括肾门、腹主动脉表面、腹主动脉旁淋巴结,右侧包括肾门、下腔静脉表面、下腔静脉旁、下腔静脉后、腹主动脉下腔静脉间淋巴结。结果 患者手术时间为(138±14)min,清扫淋巴结(14.0±4.5)枚,18.2%(4/22)的患者为淋巴结阳性。随访(14.3±6.3)个月,其中2例患者出现膀胱内肿瘤复发,1例淋巴结转移患者死于肺转移。结论 机器人辅助腹腔镜改良腹膜后淋巴结清扫术安全可行,对显露肾门、下腔静脉后方、腹主动脉下腔静脉间淋巴结的效果令人满意。  相似文献   

16.
目的探讨低位直肠癌侧方淋巴结转移规律及侧方清扫的意义。方法120例低位直肠癌患者分为两组,A组按全直肠系膜切除术(TME)行根治性手术,B组在TME基础上加做侧方淋巴结清扫,2组辅助治疗相同,分析两组的侧方淋巴结转移情况、局部复发率、远处转移率及生存率。结果侧方淋巴结转移是腹膜返折以下直肠癌的重要转移途径,占低位直肠癌的16.7%;侧方淋巴结转移常发生在低分化及粘液腺癌,也与肿瘤浸润深度有关;B组较A组局部复发率降低10.6%(P〈0.05),总生存率提高18%(P〈0.01)。结论腹膜返折以下直肠癌应行侧方淋巴结清扫,这可以降低复发率和提高生存率,侧方淋巴结转移与肿瘤生物学特性有关,侧方淋巴结转移情况可以指导术后治疗。  相似文献   

17.
目的:探究乳腺癌患者的乳腺肿块及腋窝淋巴结的超声声像图特征和腋窝淋巴结转移的关系.方法:选择2018年6月~2019年3月来本院进行治疗的乳腺癌患者84例作为调查对象,术前对所有患者落实高频二维超声以及多普勒彩色超声的检验,检查患者的乳腺肿块情况,并对患者腋窝淋巴结进行检验,对超声声像图表现加以记录.对所有患者术中进行淋巴结清扫,并对超声检验结果和淋巴结清扫结果进行比较.结果:本文84例患者经病理检验均明确得到确诊,经淋巴结清扫得出45例患者存在淋巴结转移,39例患者没有淋巴结转移,P>0.05;淋巴结转移患者图像的毛刺相对于无淋巴结转移患者而言更加的突出,P<0.05;淋巴结转移患者血流分级比无淋巴结转移更高,P<0.05;经超声判断可疑淋巴结转移患者高于非转移者,P<0.05.结论:通过超声手段检验乳腺癌患者的乳腺肿块和腋窝淋巴结,肿块,毛刺真和血流分级等都提示患者可能存在腋窝淋巴结的转移,能够为乳腺癌腋窝淋巴结转移术前预测提供科学的参考价值.  相似文献   

18.
Cserni G  Szúcs M  Svébis M 《Orvosi hetilap》2000,141(50):2711-2715
Surgical treatment of the axilla in breast cancer patients is a controversial issue, as not only staging must be ensured, but also regional disease control. Twenty seven histologically verified axillary recurrences encountered over a period of 20 years were analysed according to primary tumours and their axillary metastases. The median age of the 27 investigated patients was 57 years. Axillary recurrences occurred in 7 node negative patients (26%), 10 (37%) and 6 (22%) patients with 1-3 and more than 3 positive nodes, respectively. The number of histologically assessed lymph nodes was less than 6 in more than one third of the patients. No axillary status was available in 4 cases. Extracapsular axillary tumour spread seemed high (63%) in the recurrent group. Axillary recurrences may sometimes occur even after adequate surgical and radiotherapeutical interventions, and axillary nodal status established on the basis of low lymph node numbers and extracapsular tumour spread may predispose to this. Such features must be considered when planning adjuvant treatment options.  相似文献   

19.
目的 探讨乳腺癌彩色多普勒血流参数及血流丰富程度与淋巴结转移的相关性.方法 将68例乳腺浸润性导管癌患者按有无淋巴结转移分为Ⅰ组(无淋巴结转移组,37例)和Ⅱ组(有淋巴结转移组,31例),Ⅱ组再根据淋巴结转移程度以胸小肌为标志分为Ⅱ a组(胸小肌外侧淋巴结转移组,19例)和Ⅱ b组(胸小肌后侧、锁骨下淋巴结转移组,12例).测量病灶的彩色多普勒血流参数[血流收缩期峰值流速(PSV)、血流阻力指数(RI)]及血流丰富程度(按Alder分级),比较其与淋巴结转移的关系.结果 Ⅰ组和Ⅱ组PSV、RI比较差异无统计学意义(t=-0.19、-0.63,P>0.05);Ⅱa组和Ⅱb组PSV、RI比较差异无统计学意义(t=-1.12、-0.13,P>0.05).Ⅰ组和Ⅱ组肿瘤血流丰富程度Alder分级比较差异无统计学意义(x2=0.46,P>0.05);Ⅱ a组Alder Ⅰ、Ⅱ、Ⅲ级分别占10.5%(2/19)、63.2%(12/19)、26.3%(5/19),Ⅱb组分别占8.3%(1/12)、16.7%(2/12)、75.0%(9/12),两组肿瘤血流丰富程度Alder分级比较差异有统计学意义(x2=7.41,P<0.05).结论 乳腺浸润性导管癌血流丰富程度与淋巴结转移有一定相关性;而乳腺癌彩色多普勒血流参数与淋巴结转移无显著相关性.
Abstract:
Objective To study the association among the color Doppler flow pattern, vascular distribution and the lymph nodes metastasis in breast carcinomas. Methods Sixty-eight patients with infiltrating mammary gland duct carcinoma were divided into the no-lymph-nodes-metastasis group (group I , 37 cases) and the lymph-nodes-metastasis group (group Ⅱ , 31 cases), group Ⅱ were subdivided into group Ⅱa (19 cases): lateral lymph nodes positive of pectoralis minor and group Ⅱ b (12 cases): rear of pectoralis minor and subclavian lymph node positive. Blood flow parameters [peak systoltc velocity (PSV),resistent index ( RI)] and vascular Alder grades were observed and measured with color Doppler ultrasound.The results were compared with the incidence of lymph node metastasis. Results PSV and RI were not significantly different between group Ⅰ and group Ⅱ (t = -0.19,-0.63,P> 0.05),and also between group Ⅱ a and group Ⅱ b (t =-1.12,-013,P >0.05). By using vascular Alder grades,there were no significant differences between group Ⅰ and group Ⅱ (x2= 0.46, P> 0.05 ), but the significant differences were observed between group Ⅱ a [10.5%(2/19) ,63.2%( 12/19) ,26.3%(5/19) in Alder Ⅰ , Ⅱ , Ⅲ grade] and group Ⅱ b [8.3%( 1/12), 16.7%(2/12),75.0%(9/12)in Alder Ⅰ , Ⅱ ,Ⅲ grade](x2 = 7.41,P<0.05). Conclusion The pattern of blood flow has no correlation with lymph nodes metastasis, vascular Alder grades of carcinoma shows some relevance with the lymph nodes metastasis in the patients with infiltrating mammary gland duct carcinoma.  相似文献   

20.
目的探索一种确定术式和评估预后的方法,以提高舌鳞癌颈部淋巴结转移诊断准确率。方法利用自动弹射活检装置在超声引导下对37例舌鳞癌颈部淋巴结穿刺活检。以颈淋巴结清扫术或颈淋巴结探查术后对淋巴结检查的病理结果为标准,比较超声引导穿刺活检与临床触诊对淋巴结转移的诊断准确性。结果超声引导穿刺活检诊断符合率为94.59%,较临床触诊的59.46%高,假阴性率低,无假阳性,两种方法对诊断淋巴结转移的准确指数差异有统计学意义。结论超声引导穿刺活检可以提高舌鳞癌淋巴结转移诊断准确率,舌鳞癌术前可常规用超声检查颈部淋巴结,对可疑转移的淋巴结进行穿刺活检以确定病变性质。  相似文献   

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