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1.
OBJECTIVE: The aim of this study was to compare the effectiveness of transvaginal power Doppler sonography with spectral Doppler analysis as an aid in preoperatively distinguishing primary ovarian carcinoma and metastatic carcinoma to the ovary (Krukenberg tumors). METHODS: Fifty women with ovarian disease were preoperatively examined with transvaginal power Doppler sonography. Six basic parameters were measured, including intratumoral peak systolic velocity, end-diastolic velocity, time-averaged maximum velocity, pulsatility index (PI), resistive index (RI), and velocity index (VeI). Blood flow analyses were detectable in all patients. Twelve patients with metastatic carcinoma to the ovary were classified as group 1; 38 patients with primary ovarian carcinoma were classified as group 2. Comparison of intratumoral blood flow analyses between the two groups was performed. RESULTS: The PI, RI, and VeI were significantly lower in patients with metastatic carcinoma to the ovary than those with primary ovarian carcinoma (P < .05). There were no significant differences in the peak systolic velocity (P = .871), end-diastolic velocity (P = .508), and time-averaged maximum velocity (P = .850) between the two groups. CONCLUSIONS: Transvaginal power Doppler sonography with spectral Doppler analysis is an effective method in evaluating intratumoral blood flow of Krukenberg tumors. Low impedance (PI, RI, and VeI) might assist us in making differential diagnoses between primary ovarian carcinoma and Krukenberg tumors according to our preliminary results.  相似文献   

2.
OBJECTIVE: We aimed to search for differences between observers and automatic and manual measurements in calculations of Doppler parameters. METHODS: The middle cerebral artery (MCA), central retinal artery, ophthalmic artery (OA), common carotid artery (CCA), vertebral artery (VA), popliteal artery (PA), interlobar renal artery (IRA), and arcuate renal artery (ARA) were evaluated in 20 healthy subjects bilaterally. Peak systolic velocity (PSV), end-diastolic velocity (EDV), time-averaged maximum velocity (TAMAX), resistive index (RI), and pulsatility index (PI) were measured from the same spectrum manually by 3 observers and automatically. Results of 4 measurements were compared by analysis of variance and Pearson tests. RESULTS: The comparison of the 4 measurements revealed significant differences for most parameters except TAMAX of the OA, VA, and ARA and PSV, EDV, and PI of the PA. An automatic calculator yielded lower PSV, RI, and PI values (except the MCA and PA) and higher EDV values compared with manual measurements. The magnitudes of difference were in the range of 1% to 16% for velocities and 4% to 14% for RI and PI. The means of difference were 3.185 cm/s for PSV of the CCA and 0.054 for RI of the IRA. Correlation was high for PSV, EDV, and TAMAX in all arteries (except TAMAX of PA) and relatively low for PI and RI in most of the arteries. CONCLUSIONS: Although our study was performed on healthy subjects, our results showed that, in most cases, readers and the automatic approach disagreed on evaluation of Doppler parameters. This may be important in preventing false diagnoses in cases with Doppler values close to upper limits and may necessitate establishment of new limits for each method.  相似文献   

3.
PURPOSE: The objective of this study was to investigate whether the retrobulbar hemodynamics in the ophthalmic (OA), posterior ciliary (PCA), central retinal (CRA), and vertebral (VA) arteries are affected in migraineurs without aura. METHODS: The eyes of migraineurs without aura and those of healthy control subjects were evaluated during both headache and headache-free periods. Retrobulbar and vertebral blood flow velocities in the OA, PCA, CRA, and the extracranial part of the VA were measured bilaterally using color Doppler sonography. The peak systolic and end-diastolic flow velocities and the pulsatility (PI) and resistance (RI) indices were determined for all arteries. RESULTS: In total, we enrolled 30 migraineurs and 31 healthy control subjects. Statistically significant differences between headache-free migraineurs and control subjects were observed in the PI and RI of both right and left PCAs and in the RI of both right and left CRAs. The PI and RI of the left VA of the migraineurs were significantly lower during both headache and headache-free periods than were those of the control subjects. Among the migraineurs, the peak systolic and end-diastolic velocities of the left VA were increased during headache periods relative to those found during the headache-free periods. CONCLUSIONS: The retrobulbar circulation and flow hemodynamics in the left VA may be altered in both headache and headache-free periods in migraineurs without aura. The differences found between migraineurs and control subjects may implicate autonomic dysfunction in migraineurs.  相似文献   

4.
OBJECTIVES: To analyze the interobserver reliability of measurement of the middle cerebral artery (MCA) pulsatility index (PI) at two different sampling sites. METHODS: This study included 100 consecutive singleton pregnancies between 24 and 40 weeks with normal fetal growth. The PI was calculated by two independent operators at proximal and distal sampling sites of the near-field MCA. Reliability analyses were performed between observers at each sampling site by means of the intraclass correlation coefficient (ICC) for agreement. Differences between observers were explored and agreement limits calculated by means of the Bland-Altman test. RESULTS: Satisfactory flow velocity waveforms were obtained successfully in each fetus at both sampling sites. Peak systolic, end-diastolic and time-averaged maximum velocities were significantly higher at the proximal compared with the distal sampling site. Conversely, PI was significantly higher at the distal compared with the proximal site. ICCs for PI were 0.3 and 0.33 at the proximal and the distal sampling sites, respectively. The 95% interval of the PI differences between observers were +0.91 and -1.14 at the proximal and +1.03 and -1.08 at the distal sampling sites. In about 30% of the cases the PI difference between observers was greater than 0.5 at both sampling sites. CONCLUSIONS: Moderate interobserver reliability in the measurement of end-diastolic and time-averaged maximum MCA flow velocities results in limited agreement of the PI calculation at both proximal and distal sampling sites. These results may preclude its clinical applicability.  相似文献   

5.
彩色多普勒超声鉴别良恶性乳腺肿物的应用   总被引:24,自引:2,他引:24  
目的 探讨彩色多普勒超声鉴别良恶性乳腺肿物的应用。 方法 95例乳腺病变住院患者,首先用二维超声明确肿块部位、形态、大小等一般情况,然后用彩色多普勒血流成像(CDFI)观察,记录血流分级,用频谱多普勒测量病灶内多处血管并记录最高的搏动指数(PI)、阻力指数(RI)和峰值流速等参数。 结果 (1)临床怀疑乳腺肿块95例,超声检出乳腺肿物93例;(2)良性组与恶性组肿物在Adle,分级存在显著性差异(P〈0.05);(3)频谱分析显示两组间峰值流速、平均流速、PI、RI之间均存在显著性差异(P〈0.05),恶性组均高于良性组。 结论 (1)彩色多普勒超声检出乳腺肿物准确,简便;(2)综合分析和评价CDFI血流Adler分级、肿物内血流速度、PI、RI等指标有助于对乳腺良恶性肿物的鉴别。  相似文献   

6.
Image-directed color Doppler ultrasonography (ICDUS) studies of 86 patients with superficial solid masses yielded significantly lower resistive index (RI) values in acute inflammatory lesions, but no significant difference between the maximum systolic flow velocities (S) of the patient groups with malignant, benign, and acute inflammatory lesions. When analyzed separately, the malignant soft-tissue tumor subgroup was shown to have significantly higher mean RI compared to that of the malignant node subgroup. We conclude that RI may be useful in the differentiation of acute inflammatory masses from other pathological entities. Malignant soft-tissue tumors, especially sarcomas, may have different Doppler features from those of carcinomatous tumors. © 1995 John Wiley & Sons, Inc.  相似文献   

7.
PURPOSE: To measure with Doppler sonography the velocity and volume of blood flow in the extracranial internal carotid artery (ICA) and vertebral artery (VA) of healthy adults and to calculate total cerebral blood flow volume (tCBFV). METHODS: Bilateral ICA and VA were examined sonographically in 180 healthy adults. Angle-corrected peak systolic (Vps), end-diastolic (Ved), and time-averaged maximum blood flow velocity (TAV) were measured in pulsed Doppler mode, and the resistance index (RI) and pulsatility index (PI) were calculated. The cross-sectional area (A) was measured on gray-scale images. Volume flow was calculated as FV = TAV x A, and tCBFV was calculated as the sum of the right and left ICA and VA volume flow. RESULTS: tCBFV was 651 +/- 96 ml/min for the entire population. There was a significant decrease in Vps, Ved, TAV, and tCBFV with age in all arteries. RI and PI values initially declined and then increased with age. Cross-sectional area increased with age in ICA but not in VA. PI and RI were higher in men than in women. Blood flow velocity and volume were higher, and RI was lower in the left than in the right VA. CONCLUSION: The Doppler sonographic assessment of extracranial ICA and VA blood flow volume may be useful for the study of cerebral hemodynamic changes in patients with cerebrovascular disorders. Age-dependent changes should be considered, for instance, in the management of intensive care patients with impaired cerebral perfusion.  相似文献   

8.
血流速度测定在乳腺肿瘤诊断中的应用价值   总被引:38,自引:1,他引:38  
作者应用彩色多普勒超声测定了76例乳腺肿瘤内血流收缩期峰速和阻力指数,并对其临床应用价值作了分析。结果表明恶性肿瘤VP值明显高于良性肿瘤,良恶性肿瘤RI值无显著性差异。统计学分析了显示良恶性肿瘤之间的临界流速值为12cm/sec,该值对直径2cm以下乳癌诊断敏感性、特异性和准确性分别为95.5%、100%和96.6%。作者认为流速测定有助于乳腺肿瘤,特别是直径2cm以下肿瘤的鉴别诊断。  相似文献   

9.
目的探讨在判断卵巢肿瘤良、恶性的诊断中,恶性危险指数(RMI4)分别与彩色多普勒超声血流阻力指数(RI)、搏动指数(PI)、时间平均最大速度(TAMXV)联合应用,判断其中最佳联合方式,并分析其诊断价值。 方法回顾150例卵巢肿瘤患者(92例良性病例,58例恶性病例)术前超声检查结果,包括二维声像图特征和频谱多普勒RI、PI、TAMXV测值;根据患者超声二维声像图像特征、绝经状态、血清CA125进行RMI4评分。记录单一变量以及双变量(RMI4分别与RI、PI、TAMXV以两种诊断标准结合)判断肿瘤为良恶性的结果与术后病理进行对照,计算各组的敏感度、假阳性率、阳性预测值、阴性预测值。 结果RMI4单独诊断时具有91%敏感性及22%假阳性率,多普勒变量中,TAMXV具有100%敏感性与49%假阳性率。而当RMI4与TAMXV的组合(同时符合二者恶性标准既判断肿瘤为恶性)具有敏感性91%与假阳性率11%。 结论彩色多普勒超声RMI4评分与TAMXV同时符合恶性标准时诊断卵巢肿瘤为恶性的判断方法,优于单一变量及其他双变量联合方式。   相似文献   

10.
OBJECTIVE: To compare the reliability of Doppler blood flow measurements of the fetal aortic isthmus (AoI) according to whether the sampling plane is obtained from the traditional longitudinal aortic arch (LAA) view or the more recently described three vessels and trachea (3VT) view of the fetal upper mediastinum. METHODS: Doppler blood flow measurements of pulsatility index (PI), resistance index (RI), peak systolic (PSV), end-diastolic (EDV) and time-averaged maximum (TAMXV) velocities were performed in the AoI of 40 fetuses between 24 and 36 weeks of gestation. All measurements were sampled in two different sonographic planes of the AoI: the LAA view, at a few millimeters beyond the origin of the left subclavian artery, and the 3VT view, just before the V-shaped junction of the aortic and ductal arches. All scans were performed by the same observer. The reliability of Doppler blood flow measurements was assessed by calculating intraclass correlation coefficients (ICCs) and limits of agreement between the two different sonographic sites evaluating the AoI. RESULTS: Mean values of PI, RI, PSV, EDV and TAMXV were similar in the LAA and 3VT views. The PI and vascular velocities were reliably measured from both sonographic sites. ICCs for variability of measurements were 0.78, 0.63, 0.63, 0.60 and 0.55 for PI, RI, PSV, EDV and TAMXV, respectively. Limits of agreement revealed minimal disagreement between the two sites of evaluation of the AoI for all measurements. CONCLUSIONS: On the basis of our observations, Doppler blood flow measurements across the fetal AoI can be reliably obtained from both the 3VT and the traditional LAA sonographic views. Since the transverse upper thoracic 3VT plane is achievable in most fetal positions, Doppler study of the AoI appears to be easier than expected.  相似文献   

11.
Color Doppler technique has been available for several years. The sensitivity of the equipment has improved and allows for assessment of tumor vascularity. We investigated multiple parameters in 258 patients, with 176 benign and 82 malignant lesions to define characteristic flow criteria. Median (25–75% quartiles) and p-values are given for benign vs. malignant lesions. Number of tumor vessels: 2 (1–2) vs. 8 (5–14), p < 0.0001; mean peak systolic flow velocity: 11.1 cm/s (6.4–14.9) vs. 18.8 cm/s (13.7–25.1), p < 0.0001; maximum flow velocity: 12.5 cm/s (6.7–18) vs. 32.5 cm/s (22.5–47.3), p < 0.0001; sum of all systolic flow velocities: 18.9 cm/s (7–34.2) vs. 147 cm/s (71.3–266.7), p < 0.0001; minimum systolic flow velocity: 8.9 cm/s (5.4–12.1) vs. 9 cm/s (6.3–11.3), p > 0.05; average resistance index (RI): 0.68 (0.58–0.72) vs. 0.75 (0.67–0.81), p > 0.05; maximum RI: 0.71 (0.65–0.78) vs. 0.88 (0.78–0.99), p < 0.0001; minimum RI: 0.64 (0.57–0.68) vs. 0.64 (0.53–0.71), p > 0.05; average A/B ratio: 3.1 (2.7–3.7) vs. 4.3 (3.2–7.7), p < 0.0001; maximum A/B ratio: 3.4 (2.9–4.6) vs. 8.4 (4.5–9.9), p < 0.0001; minimum A/B ratio: 2.8 (2.3–3.2) vs. 2.9 (2.2–3.5), p > 0.05. The data analysis shows that flow resistance in malignancies is increased. This is in contrast to gynecological malignancies, where an increased diastolic flow indicates that flow resistance is decreased.  相似文献   

12.
OBJECTIVE: To investigate variability in pulsatility/resistance indices and absolute velocities of blood flow in fetal renal arteries dependent on side and sampling site within each vessel. METHODS: Doppler blood flow measurements of pulsatility index (PI), resistance index (RI) and peak systolic velocity (PSV) and end-diastolic velocity (EDV) were performed in the renal arteries of 27 fetuses between 236 and 247 days of gestation. Velocity waveforms were sampled in both the right and left renal arteries at two different sites: proximally, close to the aorta, and distally, before any major visible bifurcation of the vessels. The intraobserver variation was measured in 15 additional fetuses. RESULTS: Mean values of PI and RI were similar in the right and left renal arteries and at the proximal and distal sampling sites of these arteries. Mean PSV and EDV were higher at the proximal compared to the distal site on both sides. For all parameters the 95% limits of agreement between measurements made in the right and left arteries and at proximal and distal sites were wide but tended to be narrower for the left renal artery and at the distal site. Intraclass correlation coefficients for intraobserver variability were 0.88, 0.89, 0.83 and 0.81 for PI, RI, PSV and EDV, respectively. CONCLUSIONS: It is important to standardize the precise site at which Doppler blood flow velocity waveform measurements are made in the renal arteries of the fetus. On the basis of our observations, we suggest that the left renal artery is the preferred vessel for sampling and that measurements should be made in the renal arterial trunk away from the aorta and before any visible branches.  相似文献   

13.
本文利用TVS-CDFI技术对134例受试者的卵巢动脉血流进行了研究,其中包括36例正常妇女。134例卵巢动脉血流频谱被显示。对A、B、A/B、PI,RI进行了测量,结果表明:卵巢恶性肿瘤的B、A/B、PI、RI与正常卵巢及卵巢良性肿块测值比较,有显著性差异(P<0.05);卵巢良性畸胎瘤的B、A/B、PI、RI与正常卵巢及卵巢良性肿块测值比较,有显著性差异(P<0.05);卵巢良性畸胎瘤的B、PI,RI与卵巢其它良性肿块及正常卵巢测值相比也有显著性差异(P<0.05)。表明TVS-CDFI检测卵巢动脉血流对鉴别卵巢的良、恶病变有意义。  相似文献   

14.
OBJECTIVE: To estimate variability of renal flow Doppler parameters during the menstrual cycle in young women, and to explore whether the parameters oscillate substantially throughout the cycle. METHODS: The peak systolic, mean, and end-diastolic velocities, pulsatility (PI) and resistance (RI) indices, acceleration time (AT) and index (AI) of the right renal artery were measured nine times during the cycle with duplex sonography in 14 healthy women (age range, 23-25 years), and correlated with plasma concentrations of 17beta-estradiol and progesterone. Coefficient of variation (CV), interclass correlation (rho), and repeatability coefficients (RC) were used to measure the variability. RESULTS: The measures of the variability for AI and AT were: CV = 45.4% and 37.3%; rho = 0.25 and 0.15; RC = 10.1 and 99.5, respectively. The CV for flow velocities varied from 24.1% to 25.5%, rho from 0.49 to 0.50, RC from 22.7 for end-diastolic to 63.3 for peak systolic velocity. The respective figures for PI and RI were: CV = 17% and 8.3%; rho = 0.21 and 0.29; RC = 0.53 and 0.15. Fluctuations of the flow parameters, hematocrit, hemoglobin, heart rate, and systolic blood pressure during the menstrual cycle were insignificant, while the diastolic blood pressure decreased by about 7 mmHg (P < 0.01) in the luteal phase. CONCLUSION: The variability of renal flow Doppler parameters during the menstrual cycle in young healthy women is substantial. However, fluctuations of the values of the parameters throughout the cycle were non-significant.  相似文献   

15.
应用能量多普勒检测正常胎儿脑动脉的血流动力学   总被引:4,自引:1,他引:4  
目的确定胎儿正常脑动脉血流参数的正常值. 方法用能量多普勒及脉冲频谱多普勒检测165例胎龄16~40周胎儿的大脑中动脉(MCA)、大脑前动脉(ACA)、大脑后动脉(PCA)、后交通动脉(PCoA)的收缩期速度(Vs)、舒张期速度(Vd)、搏动指数(PI)、阻力指数(RI)、收缩期/舒张期速度比值(S/D). 结果脑动脉血流速度参数两侧对比无显著性差异(P>0.05),MCA、ACA、PCA的血流速度与妊娠周数存在显著正相关(P<0.01),即随妊娠周数增加而增快,脑动脉的PI、RI与妊娠周数也存在显著相关(P<0.01).在妊娠末期(36~40周),脑动脉的血流速度增至最大,而PI、RI、S/D则下降至最低. 结论本文的数据可作为胎儿脑动脉血流动力学正常值的参考,并可用于临床监测胎儿的生长发育.  相似文献   

16.
PURPOSE: To assess via Doppler sonography the hemodynamic changes in the cephalic vein after creation of an arteriovenous fistula, and to compare radiocephalic and brachiocephalic fistulas. METHODS: Thirty-three hemodialysis patients and 54 controls were enrolled in the study. The cephalic vein was examined with a 7.5-MHz linear-array transducer. Doppler waveform parameters (resistance index, pulsatility index), time-averaged maximum flow velocity (TAV), peak systolic velocity (PSV), end-diastolic velocity (EDV), and the cross-sectional area of the vessel (A) were measured. Cephalic vein flow volume (CVFV) was calculated as TAV x A. RESULTS: CVFV, PSV, EDV, A, RI, and PI were 45.5, 7.2, 6.7, 7.7, 1.2, and 1.32 times higher, respectively, in the cephalic vein of hemodialysis patients compared with controls. Both CVFV and A were higher in brachiocephalic patients compared with radiocephalic patients (1,983 +/- 1,199 versus 870 +/- 322 ml/min [p < 0.05] and 50.3 +/- 38.9 versus 21.0 +/- 7.8 mm(2) [p < 0.05], respectively). CONCLUSION: The increase in cross-sectional area and flow volume of the cephalic vein is larger in patients with brachiocephalic fistulas than in those with radiocephalic fistulas; however, flow velocities and waveform parameters are not different.  相似文献   

17.
PURPOSE: The study investigated the reproducibility of orbital blood flow measurements with color Doppler imaging (CDI) at different stages of observer experience. METHODS: The subjects were 31 healthy volunteers and 2 sequential groups of 25 glaucoma patients each. Repeated blood flow measurements (usually 3 sets) in orbital vessels (ophthalmic artery, short posterior ciliary arteries, central retinal artery, and central retinal vein) were performed by the same observer in a single session in each subject. RESULTS: The parameters with the best reproducibility were the resistance index (mean coefficient of variation [COV], 3.3-8.8%), the peak systolic velocity (mean COV, 6.9-13.7%), the time-averaged velocity (mean COV, 7.2-16.0%), and the systolic acceleration time (mean COV, 8.8-12.3%). The mean COV was greater (9.9-20.3%) for the other arterial flow parameters (end-diastolic velocity and systolic acceleration) and for the venous flow velocities (maximum and minimum). The COVs of the parameters were improved by 20-40% as the observer became more experienced in ophthalmic CDI. CONCLUSIONS: We confirm the general reliability of CDI measurements in orbital vessels and show that observer experience improves reproducibility. It appears, however, that observer performance in these measurements is vessel specific.  相似文献   

18.
目的 探讨多普勒超声收缩期峰值血流速度(PSV)与阻力指数(RI)在乳腺良恶性肿瘤鉴别诊断中的价值.方法 回顾分析经手术证实的120例乳腺肿瘤患者(良性46例,恶性74例)的血流参数PSV、RI,比较两者在鉴别诊断乳腺良恶性肿瘤中的敏感性、特异性和准确性.结果 乳腺恶性肿瘤RI较良性肿瘤明显增高,两者差异有统计学意义,而PSV差异无统计学意义.以PSV>20 cm/s,RI>0.7作为乳腺恶性肿块的判定标准,PSV与RI的诊断准确性分别为55.8%、77.5%;敏感性为50.0%、77.0%;特异度为65.2%、78.3%.联合PSV与RI两项指标其鉴别准确率为79.4%.结论 彩色多普勒血流参数PSV、RI有助于乳腺良恶性肿瘤的鉴别诊断;RI的鉴别诊断价值明显优于PSV;联合两者判定可提高诊断准确性,但与单独使用RI并无明显差别.  相似文献   

19.
彩色多普勒超声对卵巢肿瘤的诊断价值   总被引:14,自引:2,他引:14  
目的 探讨卵巢良恶性肿瘤的彩色多普勒超声血流形态学和血流动力学特征。方法 对95例患者105个卵巢病变,用能量多普勒观察肿物内的血流形态学改变(包括血管的分级,血管是否有畸形),用脉冲多普勒检测肿瘤内的血流动力学。观测指标:收缩期峰值流速(VPS)、舒张末期流速(VεD)、平均流速(VM)、搏动指数(PI)、阻力指数(RI)及是否存在舒张期切迹。用逐步回归的方法对上述指标进行分析。结果 所观测的血流形态学及动力学各指标在良恶性卵巢肿瘤之间的差异均存在显著性意义。逐步回归显示,RI的意义最大。RI界值定为0.51时,其鉴别良恶性卵巢肿瘤的敏感性和特异性分别为98.0%,96.2%。结论 RI是鉴别卵巢肿瘤良恶性质的最有意义的血流动力学指标。  相似文献   

20.
目的探讨阴道超声检查诊断获得性子宫血管动静脉瘘的价值.方法回顾性分析46例有既往子宫创伤(流产或剖腹产)及滋养细胞疾病史而形成子宫及宫旁动静脉瘘,并导致阴道出血患者的彩色多普勒腔内超声检查结果:病变部位的范围、彩色血流及频谱多普勒的特点;收缩期最大血流速度(PSV)、舒张期最小血流速度(EDV)和阻力指数(RI).结果子宫及宫旁动静脉瘘病变部位均显示局限性静脉扩张,呈迂曲管状或囊状无回声区,彩色多普勒血流显像病灶显示为动静脉瘘区五彩镶嵌血流信号,脉冲多普勒示瘘口处探及高速低阻动脉频谱,血流丰富;PSV (88.57±28.82)cm/s,EDV(52.94±15.36)cm/s,RI(0.41±0.05).结论子宫动静脉瘘是创伤性子宫异常出血的原因之一,腔内彩色多普勒超声有其特征性表现,有诊断价值.  相似文献   

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