恶性血液病患者生活质量及其与社会支持的相关性

目的分析恶性血液病患者的生活质量及其与社会支持的相关性。方法采用方便抽样法选择91例恶性血液病患者,以简明健康调查问卷（SF-36）及社会支持评定量表进行问卷调查,对相关数据进行统计分析。结果恶性血液病患者生活质量中的生理机能、生理职能、躯体疼痛、健康状况、社会功能、情感职能均低于普通人群（P〈0．01）,精神健康高于普通人群（P〈0．01）;社会支持总分为（41．23±8．59）分,高于常模（t=7．408,P=0．000）;躯体疼痛、健康状况、精神健康与社会支持总分呈正相关（P〈0．05）。结论恶性血液病患者生活质量的多个维度均受到疾病的影响,社会支持尤其是主观支持能有效提高患者的生活质量。     

应对方式对恶性血液病患者生活质量的影响

目的探讨恶性血液病患者的应对方式对其生活质量的影响。方法采用一般资料调查表、医学应对方式问卷和健康状况调查量表对110例恶性血液病患者进行问卷调查。结果恶性血液病患者生活质量总分为(49.76±14.67)分,各维度得分均低于国内常模(P0.01)。面对与社会功能、精神健康、情感职能呈正相关(r=0.197、0.213、0.204);回避与精神健康呈正相关(r=0.239),与精力、生理职能呈负相关(r=-0.248、-0.192);屈服与生活质量总分及各维度呈负相关(r=-0.325~-0.675)。结论应对方式是影响恶性血液病患者生活质量的重要因素,应引导患者采取积极的应对方式,以提高其生活质量。     

溃疡性结肠炎患者术后生活质量及远期肛门功能恢复的调查分析

目的：探讨溃疡性结肠炎（U C ）患者外科术后生活质量和远期肛门功能恢复情况。方法采用中文版S F-36量表对42例U C患者术后12个月生活质量和90例健康人群生活质量进行评估比较。同时观察患者术后12个月远期肛门功能恢复情况。结果 U C患者术后生活质量在生理机能、躯体疼痛、一般健康状况、精力、社会功能、情感职能、精神健康方面与健康人群比较差异无显著意义（P＞0．05）,在生理职能方面低于健康人群,差异有显著意义（P＜0．05）。远期肛门功能恢复情况影响患者术后生活质量。便次少、肛门控便能力好的患者生活质量各维度得分均较高,并从生理机能、生理职能、躯体疼痛等方面影响术后生活质量。结论护理人员应采取有效的个体化健康教育和肛门功能恢复指导,提高UC患者术后生活质量。     

血液透析患者社会支持和生活质量的现状及其相关性分析

目的探讨血液透析（hemodialysis,HD）患者社会支持和生活质量的现状,并分析其相关性,以期为提高护理服务质量提供依据。方法便利抽样法选择2011年1—10月在沈阳军区总医院进行治疗的HD患者336例为研究对象。采用社会支持评定量表和健康相关生活质量量表（the medical outcomess tudy 36一item short form health survey,SF-36）对患者进行问卷调查。结果HD患者较正常人群获得较高的社会支持,差异有统计学意义（P〈O．05）。HD患者较正常人群生活质量差,差异有统计学意义（P〈O．01）。HD患者生活质量中躯体功能、躯体角色、躯体疼痛、活力及总体健康与社会支持总分呈正相关（P〈0．01）。结论社会支持与HD患者生活质量密切相关,护士应充分利用患者的社会支持,提高其生活质量。     

冠状动脉介入治疗术后病人生活质量状况调查

[目的]探讨冠状动脉介入治疗术后病人的生活质量。[方法]采用健康状况调查问卷(SF-36)对119例冠状动脉介入治疗术后病人的生活质量进行问卷调查,并与普通人群参考值比较。[结果]冠状动脉介入治疗术后病人SF-36各维度评分从高到低依次为生理机能、社会功能、躯体疼痛、精神健康、情感职能、生理职能、精力、一般健康状况,除精神健康、情感职能维度外,其他维度与普通人群SF-36参考值比较差异有统计学意义(P<0.01)。[结论]应加强冠状动脉介入治疗术后病人健康教育,改变不良生活方式,有效提高病人术后生活质量。     

肠易激综合征患者的症状和生存质量与性别的关系

目的 探讨肠易激综合征（IBS）患者症状、生存质量与性别的关系。方法 将500例IBS患者按性别分为两组，采用症状发生频数指标对所有患者进行肠内症状和肠外症状评估。患者生存质量采用世界卫生组织推荐的SF-36量表，对患者的一般健康状况、生理机能、生理职能、情感职能、社会功能、精神健康、躯体疼痛以及精力等8个方面进行评估，并将原始得分按SF-36操作手册换算成0～100之间对应的数值。所有结果行X^2检验。结果 女性在一般健康状况、生理机能、生理职能、情感职能、社会功能、精神健康、躯体疼痛以及精力等8个方面均显著低于男性（P〈0．01）。结论 IBS患者的症状和生存质量与性别有关。     

某三甲医院合同护士生活质量现状的调查

目的了解某三甲医院合同护士生活质量的现状,并提出相应的对策。方法以健康状况问卷和自行设计的一般情况调查表调查广州市某三甲医院的235名合同护士,并以125名正式护士和普通人群作为对照组。比较合同护士与正式护士及普通人群生活质量的差异。结果合同护士生活质量得分高于正式护士,其中总分及生理机能、躯体疼痛、一般健康状况、精力、精神健康5个维度的比较,差异具有统计学意义(均P0.05)。合同护士除在生理机能得分高于普通人群外,其余各维度得分均低于普通人群,差异具有统计学意义(均P0.05)。结论合同护士的生活质量值得关注,管理者及合同护士自身均应采取积极措施以提高合同护士生活质量。     

梗阻性黄疸患者生活质量调查分析

目的探讨梗阻性黄疸患者的生活质量状况,为不同患者提供针对性护理。方法采用中文版简明健康问卷对梗阻性黄疸患者的生活质量状况进行调查。结果梗阻性黄疸患者生活质量评分明显低于正常参照人群;不同程度黄疸患者在精神健康维度得分差异有统计学意义（P〈0．05）;不同性别患者在情感职能维度得分差异有统计学意义（P〈0．05）;〈60岁和〉160岁患者在生理机能、生理职能、躯体疼痛和情感职能维度得分差异有统计学意义（P〈0．05）。结论梗阻性黄疸患者生活质量较正常人下降,不同病情、年龄、性别的梗阻性黄疸患者的生活质量不同,应针对患者的病情、年龄、性别等特点实施个性化护理。     

营养护理对维持性血液透析患者生活质量影响的研究

目的探讨营养护理对维持性血液透析（MHD）患者营养状况和生活质量的影响。方法以2009年5月～2010年5月在我院血液透析中心行MHD的患者为研究对象,随机分成实验组和对照组。实验组在常规护理的基础上给予强化营养护理,对照组进行常规护理。比较半年后两组患者的营养状况及生活质量评分（SF-36）。结果营养护理后半年,实验组营养不良炎症评分（MIS）较基线和对照组显著降低,差异有显著意义（P〈0．05）,白蛋白、肌酐、血红蛋白等营养指标显著升高,差异有显著意义（P〈0．05）;实验组一般健康状况、生理机能、生理职能、躯体疼痛、精力、社会功能、情感职能、躯体健康总评、心理健康总评和总分较基线和对照组显著升高,差异有显著意义（P〈0．05）。结论强化营养护理可以改善MHD患者的营养状况和生活质量。     

青少年特发性脊柱侧弯患者术后生活质量和健康需求的调查

目的了解青少年特发陛脊柱侧弯（AIS）术后患者的生活质量及健康需求。方法采用健康状况问卷（SF-36）及自设的矫形术后健康需求问卷对104例AIS术后患者进行问卷调查。结果MS术后患者的生活质量各维度的得分均低于正常人群,其中生理机能得分为（72．07±12．95）分,正常人群得分为（90．62±15．40）分,组间比较差异具有统计学意义（t=-14．607,P〈0．05）。相关分析发现,术后时间与生理机能、生理职能、躯体疼痛、一般健康状况、精力、情感职能的得分呈正相关（r分别为0．734,0．302,0．277,0．363,0．318,0．417;P〈0．05）。患者术后健康需求主要集中在手术后参加体育运动的时机和活动类型,手术后是否有后遗症,以及脊柱侧弯是否影响高考体检高考填报志愿和结婚生子等方面。结论本组MS术后患者的生活质量低于正常人群,患者的健康需求主要集中在术后运动、手术效果、日常生活学习影响等方面。     

Quality of life in patients with postural tachycardia syndrome

OBJECTIVES: To quantify quality of life and identify demographic and clinical correlates of functioning in a well-characterized sample of patients with postural tachycardia syndrome (POTS). PATIENTS AND METHODS: Prospective patients were those seen at the Mayo Clinic Autonomic Disorders Laboratory from September 2000 to June 2001. Neurologists made diagnoses of POTS according to established criteria. Patients completed a questionnaire packet that included measures of quality of life (36-Item Short-Form Health Survey [SF-36]) and symptom severity (Autonomic Symptom Profile). Additional clinical information was abstracted from medical records. RESULTS: Ninety-four patients (89% female; mean age, 34.2 years) were enrolled in the study. Patients with POTS reported impairment across multiple domains on the SF-36. Physical functioning, role functioning, bodily pain, general health, vitality, and social functioning were all significantly impaired compared with a healthy population (P<.01 for all) and similar to that reported by patients with other chronic, disabling conditions. Hierarchical regression analyses revealed that symptom severity (beta = -.36, P<.001) and disability status (beta = -36, P<.001) were independent predictors of SF-36 physical component scores, with the full model accounting for 54% of the variance (P<.001). None of the variables examined accounted for a significant amount of the variance in SF-36 mental component scores. CONCLUSIONS: Patients with POTS experience clear limitations across multiple domains of quality of life, including physical, social, and role functioning. Treatment should address the multiple and varied impairments experienced by these patients and may require a multidisciplinary approach. Future research must further delineate factors, both disease related and psychosocial, that predict functioning and adjustment in this population.     

Comparison of Short Form-36 and Migraine Disability Assessment questionnaire in patients with migraine

BACKGROUND: The Short Form-36 (SF-36) and Migraine Disability Assessment (MIDAS) questionnaires are two of the most commonly used tools to measure outcomes in people suffering from headaches. Nevertheless, little is known about their interrelationship in patients with headache. OBJECTIVES: The aim of this study was to investigate the interrelationship between SF-36 and MIDAS questionnaires in patients with migraine. METHODS: We enrolled 231 patients with migraine (male/female: 43/188, mean age 35.3+/-8.1) who visited our headache clinic. They completed the SF-36, MIDAS, and a headache intake form. RESULTS: The correlation coefficients between the MIDAS score and 8 domains of the SF-36 ranged from -0.30 for the mental health domain to -0.53 for the social functioning domain (P<0.01). Canonical correlation analysis showed that the overall overlap between the 2 instruments was moderately strong (canonical correlation coefficients r=0.707 and 0.572). The overall measured redundancies for MIDAS and SF-36 scales in this study were 35.4% and 11.5%, respectively. The stepwise linear regression model showed that the social functioning domain alone explained 27.9% of variance in the MIDAS scores. Bodily pain, physical functioning, and general health domains added an additional 11.4% of the explained variance in the regression model. CONCLUSION: Despite the fact that these two measures were considerably correlated, the MIDAS and SF-36 were found to measure different aspects of the impact of headache for the sample investigated. The MIDAS questionnaire does not cover the emotional domain; therefore, an accompanying psychological questionnaire might help assess the outcome for headache studies.     

Individual quality of life is not correlated with health-related quality of life or physical function in patients with amyotrophic lateral sclerosis

We compared the change over time of individual quality of life (QOL) versus health-related QOL (HRQOL) and functional status in palliative care patients with amyotrophic lateral sclerosis (ALS). Forty-two patients with ALS performed the following assessments: the ALS functional rating scale (ALSFRS), the Sickness Impact Profile (SIP), the Short Form 36 (SF-36), and the Schedule for the Evaluation of Individual QOL-Direct Weighting (SEIQOL-DW). The SF-36 and the SEIQOL-DW were assigned at random. Patients were examined at least three times at 2-month intervals. There was a significant decrease from visit 1 to 3 (4-month period) in the function-based values of the SIP, SF-36, and ALSFRS. Despite this progressive decline of physical function and HRQOL, individual QOL as assessed by the SEIQOL-DW remained stable throughout the observation period. Correspondingly, there was a clear correlation between the ALSFRS, the SIP, and the SF-36, but no correlation between these scales and the SEIQOL-DW. The QOL domains most often named in the SEIQOL-DW were family, friends/social life, health, and profession. Thus, individual QOL appears to be largely independent from physical function in severely ill patients with ALS. Because of the characteristics of the scale, assessment of individual QOL may have an interventional value in palliative care.     

Construct validity and internal consistency of the chronic fatigue syndrome activities and participation questionnaire (CFS-APQ)

Identifying patients' activity limitations is crucial for teaching Chronic Fatigue Syndrome (CFS) patients to effectively manage their activity level. Therefore, a questionnaire to assess activity limitations/participation restrictions in CFS patients was recently constructed. In this study, the internal consistency, the discriminant validity, and the convergent validity of this measure, named the CFS-Activities and Participation Questionnaire (CFS-APQ), were investigated. Convergent and discriminant validity are considered two fundamental aspects of construct validity. An envelope containing the CFS-APQ and the Medical Outcomes Short Form 36 Health Status Survey (SF-36) was sent to 149 CFS patients. Eighty-eight out of 149 CFS patients (59.1%) filled in and returned the questionnaires. Cronbach's Alpha reliability coefficients were > 0.87. The CFS-APQ total scores correlated statistically significant with six out eight SF-36 subscales (bodily functioning, physical role functioning, bodily pain, general health perception, vitality and social functioning), with Spearman Rank correlation coefficients ranging from ? 0.34 to ? 0.78. The highest correlation coefficients were obtained between the CFS-APQ total scores and the subscales ‘physical functioning’ and ‘social functioning’, no significant correlations were observed with the SF-36 subscales emotional role functioning and mental health. In conclusion, the items of the Dutch version of the CFS-APQ have been found to have good internal consistency, and these results substantiate both the convergent and the discriminant validity of the scores obtained with this questionnaire.     

Relation of Age With Symptom Severity and Quality of Life in Patients With Fibromyalgia

ObjectiveTo examine the relation of age with symptom severity and quality of life (QOL) in patients with fibromyalgia, and to compare physical and mental health of our female patients with those of the US female general population.Patients and MethodsWe studied 978 patients with fibromyalgia from May 1, 2001 through April 30, 2004, and divided them into age groups of young (≤39 years), middle-aged (40-59 years), and older (≥60 years). They completed the Fibromyalgia Impact Questionnaire and the Short Form-36 Health Status Questionnaire (SF-36). Standardized SF-36 physical and mental health summary scores were compared with those of the US female general population of similar age. One-way analysis of variance and post hoc paired t test analyses were performed to detect differences across age groups.ResultsPairwise comparison found young and middle-aged patients having worse fibromyalgia symptoms in all subscales except the anxiety subscale compared with older patients (P≤.01). Similarly, these young and middle-aged patients had worse QOL in the SF-36 mental component summary, as well as SF-36 general health perceptions, vitality, social functioning, and mental health index, compared with older patients (all P<.001). When the QOL of our female patients was compared with that of the US female general population of similar age with standardized SF-36 scores, all age groups had lower QOL in physical, as well as mental, health, with more reduction in physical health, particularly in young patients.ConclusionOur study shows that symptom severity and QOL differ across age groups in patients with fibromyalgia, with young and middle-aged patients having poorer QOL and worse fibromyalgia symptoms than do older patients. QOL in physical health was reduced more than in mental health, particularly in young patients, compared with the general population.     

Health-related social disengagement in elderly diabetic patients: association with subsequent disability and survival

OBJECTIVE: We examined the relationship between health-related social disengagements, as opposed to disengagements related to financial and other non-health-related factors, and subsequent risk of disability and death among initially nondisabled elderly diabetic patients enrolled in Medicare Managed Care plans. RESEARCH DESIGN AND METHODS: We used data from the Medicare Health Outcomes Survey (HOS) Cohort 1 Baseline (1998) and Cohort 1 Follow-Up (2000). Through mail and telephone surveys, trained interviewers collected information on sociodemographic variables, physical and mental health functioning (using Medical Outcomes Study Short Form-36 [SF-36]), activities of daily living (ADL), and medical conditions. This study reported on diabetic subjects aged >or=65 years with no ADL disability at baseline (n = 8949). Health-related social disengagement (degree to which physical health or emotional problems interfere with social activities) was derived from the social functioning subscale of SF-36 (range 0-100; higher scores depicting better social functioning). RESULTS: For each 10-point increase in social functioning score at baseline, older diabetic subjects in our study experienced an 18% less chance of any ADL disability (odds ratio [OR] 0.82, 95% CI 0.75-0.89; P < 0.001) and a 12% less chance of death (0.88, 0.78-1.00; P = 0.043) over a 2-year period, adjusting for demographic factors, comorbidities, depression, and general health (assessed by the SF-36). CONCLUSIONS: Among initially nondisabled older diabetic subjects, health-related interferences with social activities at baseline may be early warning signs of subsequent ADL disability and premature death, independent of other measures of health status.     

The MOS 36-item short-form health survey (SF-36). I. Conceptual framework and item selection.

A 36-item short-form (SF-36) was constructed to survey health status in the Medical Outcomes Study. The SF-36 was designed for use in clinical practice and research, health policy evaluations, and general population surveys. The SF-36 includes one multi-item scale that assesses eight health concepts: 1) limitations in physical activities because of health problems; 2) limitations in social activities because of physical or emotional problems; 3) limitations in usual role activities because of physical health problems; 4) bodily pain; 5) general mental health (psychological distress and well-being); 6) limitations in usual role activities because of emotional problems; 7) vitality (energy and fatigue); and 8) general health perceptions. The survey was constructed for self-administration by persons 14 years of age and older, and for administration by a trained interviewer in person or by telephone. The history of the development of the SF-36, the origin of specific items, and the logic underlying their selection are summarized. The content and features of the SF-36 are compared with the 20-item Medical Outcomes Study short-form.     

护理干预对永久性结肠造口患者ESCA、SF-36评分的影响

目的探讨护理干预对永久性结肠造口患者自我护理能力量表(ESCA)、健康调查简表(SF-36)各维度评分的影响。方法将90例永久性结肠造口患者随机分为对照组与观察组各45例,对照组仅接受结肠造口常规护理干预,观察组则在此基础上再联合延伸护理干预,对比2组患者护理干预前后的ESCA、SF-36各维度评分。结果护理干预前,2组患者ESCA量表自护技能、自护责任感、自我概念、自护知识4个维度评分差异无统计学意义(P0.05);护理干预后,2组患者ESCA量表4个维度评分较干预前升高(P0.05),且观察组评分高于对照组(P0.05)。护理干预前,2组患者SF-36量表生理功能、社会功能、生理职能、情感职能、躯体疼痛、精神健康、总体健康、活力8个维度评分差异均无统计学意义(P0.05);护理干预后,2组患者SF-36量表8个维度评分均较干预前升高(P0.05),且观察组评分高于对照组(P0.05)。结论延伸护理干预可以改善永久性结肠造口患者的自护能力及生存质量。