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Pitfalls in the echo-Doppler assessment of diastolic dysfunction 总被引:2,自引:0,他引:2
The Doppler echocardiographic assessment of diastolic function is an essential part of the evaluation of heart failure, pericardial diseases, restrictive and infiltrative cardiomyopathies, and many other conditions. However, the echocardiographic evaluation of diastolic function has several limitations. The sonographer and physician must understand the technical factors, the effects of physiological and pathophysiological conditions, and the dynamics of pseudonormalization, all of which affect the evaluation. This article will review the most recent data essential for the proper performance and interpretation of a transthoracic or transesophageal Doppler echocardiographic examination of diastolic function. 相似文献
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Bas M. Van Dalen Osama I. I. Soliman Wim B. Vletter Folkert J. Ten Cate Marcel L. Geleijnse 《Echocardiography (Mount Kisco, N.Y.)》2010,27(3):269-274
Background: Conceptually, an ideal therapeutic agent should target the underlying mechanisms that cause left ventricular (LV) diastolic dysfunction. The objective of our study was to gain further insight into the mechanics of diastology by comparison of LV untwisting measured by speckle tracking echocardiography (STE) in young healthy adults with normal and “pseudorestrictive” LV filling, and dilated cardiomyopathy (DCM) patients with “true restrictive” LV filling. Methods: The study comprised 20 healthy volunteers with a Doppler LV‐inflow pattern compatible with restrictive LV filling but a diastolic early phase filling velocity/early diastolic velocity of the mitral annulus (E/Em) ratio <8 (“pseudorestrictive”), 20 for age and gender‐matched healthy volunteers with normal LV filling and an E/Em ratio <8, and 10 DCM patients with “true restrictive” LV filling and an E/Em ratio >15. LV untwisting parameters were determined by STE. Results: Compared to healthy subjects, DCM patients had decreased peak diastolic untwisting velocity (−62 ± 33 degrees/s vs −113 ± 25 degrees/s, P < 0.01) and untwisting rate (−15 ± 9 degrees/s vs −51 ± 24 degrees/s, P < 0.01). Compared to healthy subjects with normal LV filling, healthy subjects with “pseudorestrictive” LV filling had increased peak diastolic untwisting velocity (−123 ± 25 degrees/s vs −104 ± 30 degrees/s, P < 0.05) and untwisting rate (−59 ± 23 degrees/s vs −44 ± 22 degrees/s, P < 0.05). Conclusion: Faster LV untwisting plays a pivotal role in the rapid early diastolic filling occasionally seen in young healthy individuals. In contrast, in DCM patients untwisting is severely delayed and this impairment to utilize suction may reduce LV filling. (Echocardiography 2010;27:269‐274) 相似文献
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Impaired Left and Right Ventricular Systolic and Diastolic Function in Response to Exercise in Patients with Diastolic Dysfunction 下载免费PDF全文
Meena Narayanan M.D. Alyssa Bamba R.D.C.S. P.A. Shuang Liu M.D. Tasneem Z. Naqvi M.D. F.R.C.P. M.M.M. 《Echocardiography (Mount Kisco, N.Y.)》2016,33(8):1209-1218
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Prevalence and determinants of left ventricular diastolic dysfunction in obese subjects and the role of left ventricular global longitudinal strain and mass normalized to height 下载免费PDF全文
Frank Lloyd Dini MD Iacopo Fabiani MD Mario Miccoli PhD Gian Giacomo Galeotti MD Nicola Riccardo Pugliese MD Andreina D'Agostino MD Alessandra Scartabelli MD Lorenzo Conte MD Guido Salvetti MD Ferruccio Santini MD Roberto Pedrinelli MD 《Echocardiography (Mount Kisco, N.Y.)》2018,35(8):1124-1131
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Alveolar cell carcinoma, a neoplasm associated with pre-existing inflammatory lung disease, has not been reported previously in patients with sickle cell disease. We present such a patient and suggest that chronic pulmonary scarring in this setting predisposed to development of his malignancy. As survival increases in individuals with sickle cell disease, alveolar cell carcinoma must be considered in these differential diagnosis of otherwise unexplained chronic pulmonary infiltrates. 相似文献
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