应用收缩时间间期估计冠心病患者左心室功能的初步报告

(一)本文初步报告了应用国产心电心音图机与心电图机组装成的三导联记录仪对50例冠心病患者进行收缩时间间期测定以估计其左室功能,并以50例正常人为对照。 (二)从几项心脏收缩时间间期的指标分析的结果,表明冠心病组PEPI延长,LV-ETI缩短,PEP/LVET比值增大,在正常人隐型冠心、心绞痛及陈旧性心肌梗塞等组中, PEPI依次逐一延长,PEP/LVET比值依次逐增加,LVETI除心肌梗塞组外也逐一缩短。 (三)对STI测定的几项指标,在冠心病组中的改变机理,以及PEP/LVET比值数值分布作了初步探讨。     

海拔2300米地区电炉炼钢工心脏收缩间期测量分析

本文对位于海拔2300米地区128名电炉炼钢工心脏收缩间期(STI)资料按5年为一工龄组,共计四组进行整理、统计和分析。全部炼钢工应用心阻抗图,按规定操作方法描记和测量Q-S_2、LVET、PEP。并用Weissler回归方程校正后分别用QS_2I、LVETI、PEPI表示、计算了PEP/LVET。资料经统计学处理。结果表明QS_2I、LVETI随工龄增长而延长(P<0.05),PEP/LVET≥0.41检出率为21.9％,均属轻度范围,随工龄而提高(P<0.05)。本文合计值PEPI133.4±12.67(PEP107.2±14.41);PEP/LVET0.36±0.05比平原和高原地区资料中心正常男性组延长或增大(P<0.05-0.01)。我们认为海拔2300米地区电炉炼钢工左室功能是减低的,但就其程度来看,尚属于轻度范围,对多数人来说可能是适应性改变。     

用收缩时间间期评价甲状腺机能亢进及减退患者的左心室功能

本文对129例甲状腺机能亢进、正常或低下的患者作了 STI 测定。甲亢者表现 PEPI 缩短,PEP/LVET 变小,经适当治疗后可恢复正常。甲低者则有PEPI 延长,PEP/LVET 增大。一些心功能参数与血清 TT_3或 TT_4之间有线性相关。本文表明,甲亢或甲减时可引起左室功能改变,STI 测定对评价心脏对甲状腺激素水平变化的反应是一种有价值的方法。     

体育训练对中年妇女心功能的影响

目的 研究体育训练对中年妇女心功能的影响。方法 用无创性心功能测定方法中的心脏收缩间期(STI)测定法，将55例中年妇女分为运动组25例和非运动组30例，并与青年组30例作为对照组。结果 运动组与非运动组的Q—S2I、LVETI、PEPI、ICT、Q—S1、PEP／LVET间的数值均无显著性差异。但运动组的PEPI、ICT、PEP／LVET、ICT／LVET数值均大于非运动组。结论 年龄增长并非是造成心功能低下的唯一因素，而与适宜的运动量和参加运动时间的早晚有关。运动强度适中，早期参加锻炼有利于保持心功能的良好状态。     

甲状腺机能减退病人的心功能研究

用电机械图和胸阻抗图测定了24例甲状腺机能减退病人与86例正常人的心功能,对比结果表明,甲减病人的左心室收缩功能和泵血功能均降低,舒张功能改变不明显。甲减组心功能降低的程度,以PEP/LVET比值的均值来看较显性糖尿病组、冠心病组为重,与陈旧性心肌梗塞相当。甲减病人STI变化特点主要是PEP延长。STI不仅是评价甲减病人心功能降低程度的指标,且可做为治疗中的监测指标。     

大学生心脏收缩时间间期的性别差异及与心率的相关分析

用微机自动检测的方法测定了93名大学生(男50,女43)的心脏收缩时间间期(STI),并进行了STI与心率的相关回归分析。结果表明STI的多数指标女性较男性稍高,其中MST、ICT性别差异非常显著,EMT差异显著;而PEP/LVET、ICT/LVET、Qu/LVET、EML、PWTT等指标性别差异不显著。男组和女组的EMT、LVET、PEP、MST、ICT与心率有非常显著的负相关;而PEP/LVET、ICT/LVET、Qu/LVET及EML、PWTT与心率不相关。     

老年人心脏收缩时间间期的初步观察

STI测定表明壮、汉两民族间,男女间无显著差异。按平均心率计算STI,老年组的LVET与EMT均比中年组明显延长;按不同心率分组,在心率为60～69次/分时,老年组的EMT、LVET、EMTI、LVETI等比中年组明显延长。STI各项指标与心率的相关性分析表明,EMT、LVET与心率呈负相关,EMTI、LVETI与心率呈正相关。195例的EMT、LVET、EMTI、LVETI均与年龄呈正相关。     

67例先天性心脏病患儿心脏收缩时间间期测定研究

对67例先天性心脏病患儿进行心脏收缩时间间期(STI)测定研究,以了解左室功能。结果:心内分流的法乐氏四联症、室缺及房缺均表现为PEPI延长、LVETI缩短和PEP/LVETI增大,反映左室功能降低。心外分流的动脉导管未闭ICTI明显缩短,反映后负荷减小,PEP/LVETI稍增大,提示左室功能降低不明显,这些特征有助于动脉导管未闭与心内分流先天性心脏病的鉴别诊断。     

室间隔缺损左心室功能与心脏大小关系的探讨

为探讨室间隔缺损(简称室缺)左室功能与心脏大小的关系,作者对30例(男16,女14,年龄6～12岁)室缺患儿进行收缩时间间期(STI)与心脏体积指数(VI)的对照和相关研究。其结果:STI除QS_2外,其余指标测值差异均非常显著(包括LVETI、PEPI、QS.I、PEP/LVETI等);且这些指标与肺循环血流量/体循环血流量比值(Qp/Qs)分流率,左室平均压、肺动脉平均压,缺损面积均呈高度正相关;PEP/     

159例正常人左室收缩时间间期的测定

应用同步记录心电图、心音图和颈动脉搏动图测定左室收缩时间间期(STI),并用回归分析法,发现心率对QS_2、LVET和PEP呈显著负相关;QS_2和LVET在男女性别方面也有显著差异;PEP/LVET则不受心率和性别影响。本文根据195例正常成年人测定结果,求出STI正常值,为临床提供诊断依据。     

法乐氏四联症根治术前后左室功能评定

对24例法乐氏四联症患儿采用心机械图法进行根治术前后STI测定,以评定左室功能.术前表现为LVETI缩短.PEPI延长和PEP/LVETI增大,提示左室功能降低:STI改变与主动脉径/肺动脉径比值有一定关系.根治术后2~3周STI趋于正常,3~4月恢复正常,反映畸形矫治后3~4月左室功能恢复正常.本文对根治术前后左室功能变化的机理进行了探讨.本结果可为了解此症患儿术后左室功能恢复至正常的时间,评定手术疗效和控制恢复期活动量等提供有价值的资料.     

老年高血压病静息状态心缩时相分析

本文对40例老年高血压病人及相关对照进行静息状态下心缩时间间期测定。对年龄、性别、病程、心率、收缩压、舒张压、平均动脉压、总电机械收缩时间(QS_2I),射血前期(PEPI)、左室射血时间(LVETI)及(PEP/LVET)之比,11项指标进行了统计学分析。认为心缩时间间期可在心电图、胸部X线、M型超声心动图发现左心室肥厚前证实高血压病人左心功能已有损害。     

Dynamic observation on systolic time intervals in children with ventricular septal defect,atrial septal defect and tetralogy of Fallot before and after Radical Surgery

Summary Dynamic observations on systolic time intervals (STIs) have been undertaken in 24 children with ventricular septal defect (VSD), in 16 with atrial septal defect (ASD) and in 12 with tetralogy of Fallot (TF) before and after radical surgery by simultaneous recording of electrocardiogram, phonocardiogram and carotid pulse tracing. In comparison with the STIs in normal children, the left ventricular ejection time index (LVETI) was significantly shortened, the pre-ejection period index (PEPI) significantly prolonged, and the ratio index of PEP to LVET (PEPI/LVETI) and that of isovolumic contraction time (ICT) to LVET (ICTI/LVETI) were significantly increased in the three groups of congenital heart disease before surgery, indicating definite impairment of the left ventricular performance. The dynamic changes after surgery were: In VSD, the abnormal degree of STIs was even greater at the early postoperative period for about 2–3 weeks, and since then it became improved gradually and nearly normal at the 7th-10th months. In ASD, STIs promptly became entirely normal at the 2nd-3rd weeks after surgery. In TF, STIs became approximately normal at the 2nd-3rd weeks after surgery, and were entirely normal at the 3rd-4th months. The changes of STIs after surgery were chiefly related to the improvement of hemodynamics. The left ventricular performance became normal much more slowly in VSD than in ASD and TF, and the reason was probably that left ventricular hypertrophy was present with impairment of myocardial contractility in the former. The measurements of STIs can sensitively reflect the dynamic changes of the left ventricular performance in children with VSD, ASD and TF before and after radical surgery, and can be used to monitor the state of the left ventricular performance after surgery to provide useful information for the evaluation of the effects of surgery and for supervision of the physical activity of the children during convalescense.     

慢性肾功能不全时测定左心室收缩时间间期的意义

本文报道了36例慢性肾功能不全患者的左心室收缩时间间期测定结果,并探讨其临床意义。作者认为,该项检查在慢性肾功能不全患者中有实际应用的价值;有关PEP/LVET比值和多种病理因素的相关分析表明,尿毒症晚期心肌病变确非单一因素引起。     

Effects of shengmaiyin and danshen-chuanxiong decoction on preventing cardiopulmonary changes in adults caused by a high-altitude environment

Compared with the cardiopulmonary function of the healthy adults on the plateau at an altitude of 4475 m and of 2500 m, the HR was faster, LVET was shorter, PEP/LVET rate was larger (P less than 0.05 or P less than 0.01) in the former. Besides the FEV1% and FEF25%, the FVC, FEV1.0, MMF, PEFR, FEF75% and FEF50% were all elevated (P less than 0.05 or P less than 0.01). After the villagers at the altitude of 2500 m area entered the area at the altitude of 4475 m, their LVETI became shorter, PEPI became longer, and PEP/LVET rate was increased (P less than 0.05 or P less than 0.01). Besides FEV1% and PEFR, other values of pulmonary function were increased obviously (P less than 0.05 or P less than 0.01). The Shengmaiyin could efficiently protect the villagers from the plateau reaction described above, while the Danshen-Chuanxiong decoction was not satisfactory.     

糖尿病人中左心功能的变化

41例糖尿病人和55例正常人测定了收缩时间间期和舒张时间间期。糖尿病人中[PEP]I,ICT,P/L值有意义的增加,而[Q-S_2]I,[LVET]I,A/E-O%,IRT,SFW/RFW与正常人无明显差异。P/L值异常发生率最高,达24.4%。故收缩时间间期,尤其P/L值可作为了解糖尿病心脏功能改变的较好临床指标。     

STI测定早搏后强化对估价冠心病心肌储备功能的初步探讨

通过测定33例早搏患者早搏前后心动PEP/LVET的变化来反映早搏后强化作用,其中24例冠心病测定结果表明心功能损害较重者,强化作用较明显,以此可以估价心肌储备功能,讨论了早搏后强化作用下PEP、LVET和PEP/LVET的变化及其发生机理。