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Our study reports peritoneal diffuse malignant mesothelioma (DMM) in a 43 years old male patient, with no exposure to asbestos in his medical history; the partner of the patient was also not exposed to asbestos. The exposure to X-rays was also excluded. Different pathogenic mechanisms for the pathogenesis of a peritoneal diffuse malignant mesothelioma in this patient can be hypothesized, for example, SV40 infection and genetic susceptibility; a minimal domestic exposure to asbestos can be not excluded. Therefore, further studies in a larger number of subjects are necessary to determine whether one or all of these hypothetic pathogenic mechanisms are more significant for the development of malignant mesothelioma.  相似文献   

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We report a case of bilateral hydronephrosis caused by pseudolymphoma of bilateral renal pelves. A 52-year-old woman with Sjogren's syndrome and bronchial asthma was found to have bilateral hydronephrosis. Abdominal plain computerized tomography showed an irregular thickening of the bilateral renal pelves with moderate hydronephrosis. The gallium scintigraphy revealed intense tracer uptake in bilateral renal pelves. Open biopsy of the right renal pelvis was performed under the diagnosis of malignant lymphoma. The pathologic diagnosis was pseudolymphoma of the renal pelvis. Steroid therapy dramatically improved pseudolymphoma and hydronephrosis within a month. There were no signs of recurrence.  相似文献   

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Leiomyoma of the bladder causing bilateral hydronephrosis: a case report   总被引:2,自引:0,他引:2  
We report a case of bladder leiomyoma with marked bilateral hydronephrosis caused by chronic urinary retention. Surgical finding was that the mass was smooth, fist-sized and had a thin stalk connected to the bladder wall. The tumor was completely removed. Histopathological diagnosis was leiomyoma of the bladder and the post-operative course was uneventful.  相似文献   

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A 28-year-old man visited our hospital complaining of the ulcerous lower extremity. An angiography showed the stenosis of the dorsal digital artery. The clinical diagnosis was Buerger's disease. The administration of prostaglandin I2 (PG I2) and antithrombotic drug were done. The ulcerous lower extremity improved. But a computerized tomographic scan of the abdomen showed the bilateral hydronephrosis incidentally. A retrograde pyelography (RP) revealed the bilateral ureteral strictures. We suspected the etiology was the retroperitoneal fibrosis associated with Buerger's disease.  相似文献   

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腹膜间皮细胞瘤(附8例报告)   总被引:2,自引:0,他引:2  
目的 探讨腹膜间皮细胞瘤的诊治方法。方法 回顾性分析8例腹膜间皮细胞瘤患者的临床资料。结果 男5例,女3例。平均年龄42.6岁。病程平均3.5个月。临床主要表现为腹疼、腹胀,腹部包块及腹水。8例术前均误诊。均行手术治疗(姑息性切除2例,单纯活检6例)。术后2例自动出院,另6例术后平均生存3.7个月(2-10个月)。结论 间皮细胞瘤可分为良性和恶性,但从其生物学行为看,组织形态良性者亦可有恶性表现。该病早期无特殊症状,易于误诊;绝大部分确诊需通过剖腹探查。治疗多主张综合治疗,手术尽可能根治性切除肿瘤,术后配合腹腔内化疗和腹部放疗。该病预后差。  相似文献   

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恶性腹膜间皮瘤十例的诊治分析   总被引:5,自引:0,他引:5  
目的总结恶性腹膜间皮瘤的诊治经验 ,提高对本病的认识。方法回顾性分析10例恶性腹膜间皮瘤的临床资料。结果 恶性腹膜间皮瘤以腹部肿块及腹痛为主要临床表现 ,大体病理局限型 7例 ,弥漫型 3例。临床误诊 7例。 9例患者行 16次手术治疗 ,接受 1次手术者 4例 ,2次手术者 3例 ,3次手术者 2例 ,首次手术 7例能完整切除肿瘤。术后复发 4例 ,3例再次手术。 1年内死亡 5例 ,2年内死亡 6例 ,最长存活已 9年。结论恶性腹膜间皮瘤较为罕见 ,临床易误诊 ,本病预后较差 ,对于局限型恶性腹膜间皮瘤应力争手术切除  相似文献   

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Benign multicystic peritoneal mesothelioma (BMPM) is a rare disease with good short-term prognosis and rare malignant transformation. However, its biological significance remains unexplained. A neoplastic origin is considered by many authors to require a surgical excision, based on the high recurrence and progressive growth rate of the tumors. However, alternative or integrative treatment options have also been proposed. A 45-year-old woman presented to our unit with a history of occasional discomfort and pain in the left hip. On physical examination, we noticed a tough-elastic, fixed mass located in the iliac fossa. Computed tomography scan detected a mass with multiseptated cystic-like areas. Due to the similarity of these findings to a primitive sarcomatous tumor of the retroperitoneum, an arteriographic study was also performed. The patient underwent en bloc resection of the mass, including a segment of the sigmoid colon. The final pathologic diagnosis was cystic mesothelioma. Further studies are needed to better understand the etiology and pathogenesis of this rare disease, and to define a more tailored treatment plan.  相似文献   

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A true hermaphrodite with a 46 XX/47 XXY karyotype, gynaecomastia, hypospadia and scrotal gonads was investigated. Gonadectomy performed at 14 years of age revealed bilateral ovotestes. The ovarian portion contained follicles of all developmental stages. The testicular portion was immature consisting of seminiferous cords with Sertoli cells at various steps of differentiation and few germ cells within massive aggregates of collagenous connective tissue. Leydig cells as well as germ cells remained in an embryonic stage of development. Sections of a differentiated Wolffian duct (ductuli efferentes, epididymis, vas deferens) as well as of a Müllerian duct (hypoplastic fallopian tube) were found adjacent to both gonads. Postoperative treatment consisted of androgen substitution therapy leading to progression of puberty.  相似文献   

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Peritoneal mesothelioma. A report of 4 cases   总被引:2,自引:0,他引:2  
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In this study, we have reported an unusual case of giant hydronephrosis of the right kidney diagnosed as a result of pain, and upon palpation the detection of an abdominal mass. An ultrasound examination also indicated the possible presence of a large abdominal liquid mass. The hydatic serology was negative. A complementary CT scan and retroperitoneal approach confirmed the diagnosis of a right giant hydronephrosis with a liquid content of 8 liters, caused by stricture at the pyeloureteral junction with destruction of the kidney. The liquid was drained off. Based on the findings in this case, the pathogenesis, diagnosis and investigation of giant hydronephrosis have been discussed. In the event of giant hydronephrosis with total destruction of the kidney following an anomaly at the pyeloureteral junction, nephrectomy has to be performed. In the presence of a retroperitoneal liquid mass and in the absence of other pathological signs, the diagnosis of a possible giant hydronephrosis should be taken into consideration.  相似文献   

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