自然组织谐波成像与基波成像在正常肾脏声像图中的对比观察

目的：通过自然组织谐波成像（NRHI）与常规基波成像（FI）的对比观察。研究NTHI改善正常肾脏声像图质量,提高诊断率。方法：对253例（标准受检者180例,肥胖受检者73例）正常肾脏进行观察。分析两种检查的图像质量。结果：FI成像标准受检者图像显示优良率85.0%,肥胖受检者图像显示优良率76.7%,NTHI成像标准受检者图像显示优良率96.7%,肥胖受检者图像显示优良率87.7%。结论：无论是标准受检者还是肥胖受检者NTHI的图像质量均较FI的图像质量明显改善。大大提高了诊断的准确性。     

组织谐波成像在肥胖者肝胆超声诊断中的应用价值

目的：探讨组织谐波显像（THI）在肥胖者肝胆超声诊断中的应用价值。方法：采用基波显像（FI）和两种频率THI对50例肥胖者肝胆显像效果进行对比观察。结果：1．肝脏显像，FI，THI1，THI2状态近场显示不满意比率分别为46％，6％和10％，中，远场显示均不满意比率分别为4％，46％和42％，远场显示不满意比率分别为10％，32％和30％，2．胆囊显像，FI状态囊内混响伪像明显者占56％，THI1，THI2状态所有病例均得到改善，结论：THI对肥胖者肝脏近场图像质量及胆囊内混响伪像改善明显。对肝脏中，远场显像效果不如FI。     

组织谐波成像在胆囊病变超声诊断中的应用

目的通过常规基波成像（FI）和组织谐波显像（THI）技术对比,探讨超声自然组织谐波成像在胆囊病变中的应用价值。方法采用基波显像和组织谐波成像对63例胆囊病变患者进行对比观察。结果63例患者FI与THI图像对比分析,后者图像整体质量均得到明显改善。结论组织谐波成像能明显改善二维图像质量,有助于提高超声对胆囊病变的诊断准确率。     

组织谐波成像在腹部脏器的临床应用

目的 探讨组织谐波成像技术在腹部脏器的临床应用价值。方法 分别采用常规基波成像(FI)，及组织谐波成像(THI)对138例腹部脏器正常组及疾病组二维声像图及诊断检出率进行比较。结果 THI明显改善了FI状态下二维图像质量：正常腹部脏器结构及层次显示清晰，疾病组声像图特征明显，提高了检出率及鉴别诊断水平；同时，THI明显减少伪像，增加细微组织结构分辨能力，在胆囊疾病诊断中尤其有意义。结论 随着技术的不断改善，THI能为超声提供更有诊断价值的信息。     

谐波成像技术与胃充盈造影在胃癌分期诊断中的应用研究

目的 研究组织谐波成像技术(THI)与胃充盈造影在胃癌显像中对图像质量改善的影响以及在胃癌分期诊断中的临床应用价值.方法 对120例胃癌患者分别采用基波和组织谐波成像,对因各种原因基波成像(FI)不满意患者改用THI技术,观察THI对图像质量的影响,分析THI在肿瘤病灶边界范围确定、病灶浸润深度判定中的准确性,并与手术病理结果对照.结果 24例FI成像质量满意的图像THI与FI显示了良好的一致性(P>0.05),96例FI成像图像质量不满意者在THI状态下69例得到明显改善,平均改善率为 71.9%,二者差异显著(P<0.05).在胃癌分期分析中,对病灶范围小于2和5 cm以下测值的符合率较高,分别为 85.7%和82.5%,误差范围小;>5 cm以上的测值误差范围较大,符合率仅为61.8%;对浸润深度判定与手术病理结果对照,早、中、晚各期符合率分别为 66.7%、75.0%和93.3%.本组资料中超声对肝脏转移的检出率为100%,而对单纯淋巴结转移的检出率仅为60.2%.结论 THI技术能显著改善图像质量;对小病灶范围测值与手术结果有良好的一致性;对胃癌术前分期判断准确性较高;为临床术前预测肿瘤可切除性、选择合理的治疗方案提供较为可靠的量化指标.     

组织谐波成像技术在心脏显像和测值方面的临床研究

目的探讨组织谐波成像技术(THI)对图像质量及结构测量值的影响.方法对120例患者(包括多种疾病)分别采用基波(FI)、组织谐波(1.8～3.6、2.1～4.2 MHz)成像,对图像质量进行评分并根据FI评分进行分组(Ⅰ组:评分为1分的质量佳的图像;Ⅱ组:评分为2分和3分的质量差图像),而且对心脏结构进行测量.结果 (1)Ⅱ组中,THI与FI相比,图像质量明显改善;(2)两组中, THI1、THI2与FI相比,间隔及左室后壁增厚,Ⅰ组中,间隔 :(9.22±3.19) mm和(9.22±3.03) mm vs( 8.29±2.65) mm P＜0.05;左室后壁:(9.08±3.30) mm和(9.15±3.32) mm vs (8.49±3.05) mm P＜0.05.Ⅱ组中,间隔 :(11.64±3.64) mm和(11.75±3.89) mm vs (11.04±3.70) mm P＜0.05;左室后壁:(10.29±2.07) mm和(10.40±1.89) mm vs (9.50±1.86) mm P＜0.05;左室舒张末内径减小[Ⅰ组:(51.68±12.37) mm和(51.73±12.30) mm vs (52.63±12.83) mm P＜0.05;Ⅱ组:(49.94±7.38) mm和(49.88±7.64) mm vs (50.81±7.43) mm P＜0.05 ];(3)房间隔缺损患者, THI1、THI2与FI相比,缺损大小明显减小[收缩末:(20.60±11.93) mm和(21.35±12.59) mm vs (23.04±12.91) mm P＜0.05; 舒张末:(25.50±15.77) mm和(25.59±16.35) mm vs (26.74±16.35) mm P＜0.05];(4)二尖瓣狭窄患者中, THI1、THI2与FI相比,瓣口面积明显减小[(77.22±24.42)mm2和(79.80±25.24)mm2 vs (82.23±26.00)mm2P＜0.05].结论在显像差时,应用THI可以改善图像质量.在测量方面,应用FI和THI的测量值之间存在差异,THI状态下的测量标准有待于进一步研究.     

组织谐波成像在胰腺占位病变中的应用

目的探讨组织谐波成像(THI)技术在胰腺占位病变中的诊断价值.方法应用常规二维超声即基波成像(FI)和THI技术,对经病理证实的58例胰腺占位病变的检查结果,进行对比分析.结果物理性质判断符合率,FI为81.0%,THI为94.8%;肿块边界、内部回声、胰管回声的优良显示率,F1分别为77.6%、81.0%及86.7%,而THI为93.1%、94.8%及96.6%.经统计学处理,两者有显著性差异(P＜0.05).结论THI技术可明显改善常规超声图像质量,提高胰腺占位性病变的诊断符合率,是常规二维超声不可缺少的补充.     

组织谐波成像诊断胰腺占位性病变的临床应用

目的：通过常规基波成像(FI)与组织谐波成像(THI)的对比观察，探讨组织谐波成像在胰腺占位性病变诊断中的价值。方法：对比分折62例胰腺占位病变的基波成像和组织谐波成像的结果。结果：在观察胰腺病灶的边界、内部回声及胰管回声方面，在确定占位性病变的物理性质方面，组织谐波成像优于基波成像。结论：本研究表明，组织谐波成像可提高病变的清晰度及对比度，提高胰腺占位性病变的图像质量，从而提高诊断准确率。     

自然组织谐波成像在左室室壁瘤附壁血栓中的临床应用

目的：通过与基波成像(FI)的对比观察，探讨自然组织谐波成像(NTHI)在左室室壁瘤附壁血栓中的应用价值。方法：对比分析37例附壁血栓的FI和NTHI。结果：NTHI对心内膜的边界及血栓回声层次等状况的显示明显优于FI，对新生的血栓尤为明显。结论：NTHI能明显改善图像质量，尤其是对显像困难患者的声像图改善更为突出，具有很好的应用价值。     

自然组织谐波成像在儿科中的应用价值

目的　研究自然组织谐波成像 (NTHI)改善二维图像质量在儿科中的应用价值。方法　采用常规超声即基波成像 (FI)和自然组织谐波成像对 46例患儿经胸二维成像。结果　FI成像模糊的 31例患儿共 65 1个节段中有 447个节段左室心内膜显示能力 (EBD)改善 ,总改善率 68.66% ;183个节段EBD加强 ,加强率 2 8%。FI成像清晰的 15例患儿共 315个节段中 ,用NTHI显示效果好于FI的占 12 % ( 38 315 ) ;FI好于NTHI的占 10 % ( 31 315 ) ,NTHI和FI相比无显著性差异 (P >0 .0 5 )。结论　NTHI可提高患儿二维图像的分辨力和对比度 ,明显增强心内膜边界识别能力 ,改善图像质量 ,提高诊断准确率     

组织谐波显像在胰腺囊性病变诊断中的价值

目的　探讨组织谐波显像在胰腺囊性病变诊断中的临床价值。方法　经手术病理证实的 3 0例胰腺囊性病变患者行二维超声及组织谐波显像检查 ,对组织谐波显像 (THI)与基波显像 (FI)对比分析。结果　组织谐波显像对囊壁边界及内部回声结构的显示均优于基波显像。结论　组织谐波显像能显著提高图像质量 ,提高胰腺疾病的显示率和诊断的准确性。     

High-frame-rate tissue harmonic imaging enhances anatomic M-mode sections of the left ventricle in short-axis view.

BACKGROUND: High-frame-rate echocardiography (HFRE) and tissue harmonic imaging (THI) may improve image quality, thereby enabling anatomic M-mode sections of left ventricular (LV) wall segments to be visualized in various planes in the short-axis view. OBJECTIVES: The goals of this study were to compare image quality between HFRE and conventional-frame-rate echocardiography (CFRE) and between fundamental imaging (FI) and THI, and to obtain anatomic M-mode values of basal short-axis LV segments from healthy subjects for use in the evaluation of abnormal segments in patients with myocardial infarction (MI). METHODS AND RESULTS: The study included 28 healthy subjects and 15 patients with MI who underwent 2-dimensional echocardiography with an ultrasonographic system equipped with THI and anatomic M-mode. Left ventricular image cineloops at the basal short-axis view that were obtained with 3 combinations of imaging techniques (FI + CFRE, FI + HFRE, and THI + HFRE) were digitized and displayed side-by-side in random order for comparison by blinded readers. M-mode sections were done in 3 planes: anteroseptal-posterior, inferoseptal-lateral, and anterior-inferior basal segments. The THI + HFRE combination showed the best image quality with significant reduction in noise artifacts, resulting in a good signal-to-noise ratio and good tractability of all LV segments by anatomic M-mode. In healthy subjects, significant intersegmental differences existed in the diastolic and systolic thicknesses and in the percent systolic thickening of LV segments. In patients with MI, LV systolic thickening was significantly decreased in abnormal segments. No significant differences were noted in ejection fraction and fractional shortening among the 3 anatomic M-mode planes. CONCLUSION: High-frame-rate tissue harmonic imaging improved image quality, thereby allowing reproducible anatomic M-mode measurements in various planes in the short-axis view and providing a convenient objective evaluation of global and regional LV function.     

组织谐波显像诊断胰腺癌的临床应用

目的通过常规基波显像(FI)与组织谐波显像(THI)的对比观察,探讨组织谐波显像诊断胰腺癌的临床应用价值。方法对45例胰腺癌患者(肿块直径小于4cm,无远处转移)进行FI和THI检查,对2种方法所得图像质量进行对比,分析2种检查方法的诊断价值。结果在观察胰腺病灶的大小、边界、内部回声特点、胰管回声及肿块与周围血管的关系等方面,组织谐波显像明显优于基波显像。结论本研究表明,THI可提高胰腺肿块的图像质量,提高病变显示的清晰度及信息量,从而提高诊断准确率。     

Harmonic imaging in fetal echocardiography.

Noncontrast harmonic imaging (HI) has been shown to improve image quality in adults with poor acoustic windows. The utility of fetal echocardiography may be limited by suboptimal acoustic windows, and the use of HI in fetal echocardiography has not previously been defined. The purpose of this study was to compare the quality of fundamental imaging (FI) and HI in fetal echocardiography. Sixty-two fetal echocardiograms, including 44 (71%) with limited acoustic windows, were performed with the use of FI and HI. Image quality and visualization of the ventricles, valves, and the aortic and ductal arches were evaluated and compared between FI and HI. Mean HI scores were higher than mean FI scores for all the structures evaluated. Compared with FI, HI improved the image quality and visualization of cardiac structures in this group of fetuses with predominantly suboptimal acoustic windows. Harmonic imaging is a useful adjunct to FI in echocardiography, and the benefits of HI extend to cardiac imaging in the fetus.     

Harmonic imaging improves estimation of left ventricular mass

OBJECTIVES: To assess the effect of tissue harmonic imaging (THI) on assessment of left ventricular mass index (LVMI) measurements by M-mode trans-thoracic echocardiography, when compared with magnetic resonance imaging (MRI). METHODS: 20 hypertensive male subjects were studied. LVMI was measured in all subjects by both gradient-echo MRI (Lscelsint Prestige 1.9 T) and by transthoracic echocardiography (ATL HDI 5000). M-mode echocardiography recordings were taken for each patient, two with fundamental imaging (FI) and two using THI in a randomised order and the images unlabelled. Recordings were analysed off-line, by a blinded observer. LVMI by MRI was calculated using Simpson's rule on serial short axis slices of 8 mm thickness. Data are expressed as mean +/- SD. RESULTS: There was a difference in LVMI measurements between FI and THI (LVMI) (79 +/- 20 vs. 93 +/- 25 g2; p < 0.001). A lower mean difference was obtained by THI, compared to FI, when compared with MRI (2 +/- 15 vs. -32 +/- 22 g2; p < 0.001) suggesting that FI underestimates LVMI. Inter-observer variability was similar between THI and FI (4.5 +/- 15 vs. 6.4 +/- 15 g2; p = 0.46). CONCLUSION: In hypertensive males, M-mode echo derived from FI underestimated LVMI. These results imply that widely accepted reference ranges for LVMI using FI are not applicable when THI is used.     

组织谐波显像诊断肝脏病变的临床应用

目的：探讨组织谐波显像对肝脏病变的诊断价值。方法：对比分析56个肝脏病灶的基波显像和组织谐波显像结果。结果：组织谐波显像对病灶的边界和内部回声等状况的显示均明显优于基波显像,对囊性病变尤其明显。结论：组织谐波显像能明显改善图像质量,提高诊断准确性。     

组织谐波显像技术在肝胆系统疾病临床诊断中的应用

目的:探讨组织谐波显像技术(THI)在肝胆系统疾病临床诊断中的应用。方法:选择2003年—2007年常规超声检查图像不理想的78例患者,对其常规基波显像(FI)检查及THI检查结果进行比较分析。结果:肝病组及胆系疾病组在二维超声FI基础上,加入THI后,能很明显地提高灰阶对比度,脏器的内部结构及边缘回声显示有明显的改善,脏器内实性肿块的轮廓清晰度有明显改善。结论:THI可明显提高FI的图像质量,提高二维检出率,具有较高的临床诊断价值。