LIFT与切开挂线术治疗复杂性肛瘘的疗效比较

目的探讨括约肌间瘘管结扎术(ligation of intersphinc-teric fistula tract,LIFT)与切开挂线术(incision-threaddrawing procedure)治疗复杂性肛瘘的临床疗效。方法对39例经LIFT手术治疗复杂性肛瘘(LIFT组)和44例经切开挂线术治疗复杂性肛瘘(切开挂线组)的患者临床资料进行回顾性分析,观察两组手术时间、术中出血量、临床疗效、术后并发症、复发率等。结果 LIFT组治愈率87.2%,切开挂线组治愈率93.2%,两组比较差异无显著统计学意义(P0.05),LIFT组术中出血、术后创面大小、术后换药疼痛持续时间、创面愈合时间、住院时间、Wexner肛门失禁评分均优于切开挂线组(P0.05)。结论 LIFT手术治疗复杂性肛瘘具有手术创伤小、恢复快、痛苦少,复发率低等优点,可以在临床应用。     

经括约肌间瘘管结扎术与切开挂线术治疗经括约肌肛瘘的临床效果比较

目的比较经括约肌间瘘管结扎术与切开挂线术治疗经括约肌肛瘘术后疼痛、肛门功能以及创面愈合时间的疗效。方法经括约肌肛瘘病人124例,将124例病人分成两组,试验组60例,行经括约肌间瘘管结扎术;对照组64例,行切开挂线术。比较两组的肛门失禁评分、肛门功能、术后疼痛、创面愈合时间和临床疗效。结果对照组肛门失禁总分为(8.68±1.65)分,试验组为(7.03±1.46)分;对照组肛门功能总分(6.71±0.93)分,试验组为(8.04±1.11)分;对照组术后疼痛评分为(6.22±1.24)分,试验组为(3.52±1.06)分,两组以上指标比较,差异均有统计学意义(P0.05).对照组创面愈合时间为(5.31±1.32)天,试验组为(5.78±1.43)天;对照组临床总有效率为95.31%,试验组为88.33%,两组比较,差异无统计学意义(P0.05)。结论经括约肌间瘘管结扎术能够缓解经括约肌肛瘘病人术后疼痛,促进其肛门功能的提高,且临床疗效与切开挂线术比较无明显差异。     

切开挂线对口引流术治疗高位复杂性肛瘘的临床观察

目的探讨切开挂线对口引流术治疗高位复杂性肛瘘的临床疗效。方法选取我院收治的高位复杂性肛瘘患者88例作为研究对象,随机分为两组,观察组和对照组各44例。观察组患者使用切开挂线对口引流手术治疗,对照组患者采用传统的切开挂线术治疗,对照两组患者的临床治疗效果,并发症发生率以及术后的复发率等情况。结果所有高位复杂性肛瘘的患者经手术,均全部治愈,有效率100%,且无感染、大出血等情况出现。但观察组患者手术后的创面恢复时间、平均住院时间等均显著优于对照组患者,P0.05。观察组患者术后的肛门括约肌功能显著优于对照组患者。对患者进行一年左右的随访,观察组患者无一例复发,无一例出现肛门狭窄、畸形或者肛门失禁等并发症和后遗症,对照组患者复发3例,经治疗痊愈。结论高位复杂性肛瘘病变部位高而深,主、支管多,内外口不易辨认,解剖学结构较为复杂。切开挂线对口引流手术治疗高位复杂性肛瘘的临床疗效好,术后并发症发生率和复发率低,一次成功,肛门括约肌功能受损程度轻,创面恢复快,值得临床推广应用。     

切开挂线对口引流术治疗复杂性肛瘘临床疗效分析

1996～ 1 998年 ,我院对 78例复杂性肛瘘病人采用主管道低位切开 ,高位挂线 ,支管道对口引流术 (简称 :切开挂线对口引流术 )治疗 ,取得满意疗效。现对该治疗方法疗效总结报告如下。1　临床资料　　本组 78例 ,男 62例 ,女 1 6例 ,年龄 1 8～ 65岁 ,平均 41岁。病程 6个月至 2 2年 ,平均 9年。按 1 975年全国肛肠学术会议制定的肛瘘统一标准分类法进行诊断 ,低位复杂性肛瘘 2 2例 ,高位复杂性肛瘘 5 6例。外口 2个 8例 ,3个 42例 ,4～ 7个 2 8例。2　治疗方法　　患者取侧卧位 ,按常规消毒 ,铺无菌洞巾。腰俞麻醉或局麻后 ,先进行指诊 ,肛门…     

一次性切开挂线法治疗小儿肛瘘36例临床观察

我们采用一次性切开挂线术治疗小儿肛瘘36例,效果满意,现报告如下。临床资料：本组男28例,女8例;年龄最小58d,3岁以下婴幼儿24例,14岁以下小儿12例。低位肛瘘26例（单纯性肛瘘18例,复杂性肛瘘8例）,高位肛瘘10例（单纯性肛瘘8例,复杂性肛瘘2例）。治疗方法：患者取截石位或侧卧位,常规消毒铺巾。氯胺削静脉麻醉。将左手小指或食指润滑后伸入肛门内,右手持球头探针从外口或切开排脓口向直肠方向缓缓探人,直抵肛内,手指感觉探针于手指问最薄弱处引出。     

改良切开挂线术治疗马蹄型肛瘘的临床观察

目的:探讨改良切开挂线术治疗马蹄形肛瘘的临床应用价值.方法:采用改良切开挂线术治疗马蹄形肛瘘患者50例.对照组为同期切开挂线术治疗患者42例.观察两组手术时间、术后创面出血情况、术后疼痛、创面愈合时间、肛门瘢痕大小、肛门畸形、肛门功能状况以及术后复发情况.结果:治疗组与对照组比较,手术时间、术中及术后渗血时间、术后疼痛持续时间、创面愈合时间皆缩短;肛门瘢痕小;肛门畸形发生率低;肛门部分失禁发生率低;术后复发率两者差异无统计学意义.结论:改良切开挂线术治疗马蹄形肛瘘较切开挂线术效果好,值得临床推广应用.     

低位切开高位挂线术治疗复杂性肛瘘46例

我科采用低位切开高位挂线的手术方法治疗复杂性肛瘘46例,取得满意疗效,现报告如下。 临床资料：本组男38例,女8例;低位复杂性肛瘘34例,高位复杂性肛瘘12例。外口最少2个,最多6个。     

视频辅助肛瘘治疗术对比切开挂线术治疗复杂性肛瘘有效性与安全性的meta分析

目的 系统评价视频辅助肛瘘治疗术治疗复杂性肛瘘的疗效和安全性。方法 检索中国知网、万方、维普、中国生物医学文献数据库、Web of Science、PubMed、Cochrane Library及Embase数据库,时间范围从建库截止到2022年5月31日;由两位研究者独立筛选文献,并根据研究目的和质量评价标准对符合纳入标准的文献进行质量评价;使用RevMan 5.4.1软件进行meta分析。结果 研究纳入了11篇文献,共977例患者。meta分析结果显示：视频辅助组在提高治愈率[RR=1.14,95%CI为（1.04,1.24）,P<0.05],加速创面愈合[MD=–10.40,95%CI为（–13.64,–7.17）,P<0.05],保护术后肛门功能[MD=–1.32,95%CI为（–1.85,–0.79）,P<0.05],缓解术后24 h疼痛[MD=–1.23,95%CI为（–1.60,–0.86）,P<0.05],缩短手术时间[MD=–9.46,95%CI为（–17.16,–1.75）,P<0.05]和住院时间[MD=–3.87,95%CI为（–5...     

肛瘘的挂线治疗

肛瘘是常见的外科难治性疾病,治疗的主要目的是引流脓液,根治瘘管,保护括约肌的完整性和肛门功能。大多数低位肛瘘可以通过切开或切除就可以达到根治的目的。同时肛门功能也能得到保护。因为低位瘘管仅累及括约肌的下1/3。但高位复杂性肛瘘的处理仍比较棘手,当瘘管经过肛管括约     

经括约肌间瘘管结扎术治疗高位单纯性肛瘘的临床疗效

目的 评估经括约肌间瘘管结扎术(LIFT)治疗高位单纯性肛瘘的临床疗效.方法 回顾性分析2011年1月至2012年6月北京普仁医院与北京朝阳医院收治的77例高位单纯性肛瘘患者的临床资料,患者分别采用LIFT手术法(LIFT组,37例)和切开挂线法(切开挂线组,40例)进行治疗,对两组患者的手术时间、创口愈合时间、术后疼痛时间及严重程度、复发率及对肛门功能影响等进行对照分析.正态分布的计量资料采用t检验,非正态分布的计量资料及等级资料采用秩和检验,计数资料采用x2检验.结果 LIFT组和切开挂线组患者手术时间分别为(21.4±2.0) min及(20.6±1.9) min,两组比较,差异无统计学意义(t=1.911,P＞0.05).术后LIFT组仅17例感轻度疼痛,无中度以上疼痛;切开挂线组轻度疼痛7例、中度疼痛14例、重度疼痛19例;LIFT组疼痛持续时间为(3.0±1.3)d,切开挂线组为(14.1 ±1.5)d;LIFT组在术后疼痛程度及持续时间均明显低于切开挂线组,差异有统计学意义(u=-7.189,t=34.534,P＜0.05).LIFT组和切开挂线组创口愈合时间分别为(26.0±1.9)d和(40.7 ±2.8)d,肛门瘢痕面积分别为(1.24±0.20) cm2和(2.64±0.25) cm2,术后中位肛门功能评分分别为1分和4分,两组比较,差异均有统计学意义(t=26.574,26.868,Z=-7.513,P＜0.05).两组患者治疗有效率均为100％,LIFT组和切开挂线组患者痊愈率分别为51.4％ (19/37)和42.5％(17/40),复发率分别为5.4％ (2/37)和2.5％ (1/40),两组痊愈率、复发率比较,差异均无统计学意义(x2=0.605,0.433,P＞0.05).结论 高位单纯性肛瘘行LIFT治愈率高,术后疼痛轻且持续时间短,创口愈合快,肛门功能保护好,复发率低.     

Ligation of the intersphincteric fistula tract in low transsphincteric fistulae: a new technique to avoid fistulotomy

Aim To date fistulotomy is still the treatment of choice for patients with a transsphincteric fistula passing through the lower third of the external anal sphincter, because it is a simple, effective and safe procedure with a minimal risk of incontinence. However, data suggest that the risk of impaired continence following division of the lower third of the external anal sphincter is not insignificant, especially in female patients with an anterior fistula and patients with diminished anal sphincter function. It has been shown that ligation of the intersphincteric fistula tract (LIFT) is a promising sphincter‐preserving technique. Therefore, we questioned whether LIFT could replace fistulotomy in patients with a low transsphincteric fistula. Method A consecutive series of 22 patients with a low transsphincteric fistula of cryptoglandular origin underwent LIFT. Continence scores were determined using the Rockwood Fecal Incontinence Severity Index. Results Median follow‐up was 19.5 months. Primary healing was observed in 18 (82%) patients. In the four patients without primary healing, the transsphincteric fistula was converted into an intersphincteric fistula. These patients underwent subsequent fistulotomy with preservation of the external anal sphincter. The overall healing rate was 100%. Six months after surgery, the median incontinence score was not changed significantly. Conclusion Low transsphincteric fistulae can be treated successfully by LIFT, without affecting faecal continence. Division of the lower part of the external anal sphincter is no longer necessary in the treatment of low transsphincteric fistulae, which is essential for patients with compromised anal sphincters.     

改良经括约肌间瘘管结扎术治疗括约肌间型及经括约肌型肛瘘的临床效果研究

目的：观察改良经括约肌瘘管结扎术（MLIFT）治疗括约肌间型肛瘘（ISAF）及经括约肌型肛瘘（TSAF）的疗效。方法：选取2016年1月1日—2020年12月31日上海市宝山区中西医结合医院肛肠科收治的190例TSAF和ISAF患者,随机分为治疗组（行MLIFT术）、对照组（行肛瘘切开挂线术）,术后常规清创、换药治疗;比较两组术后第1、3、7、14、21、30天的创面疼痛(VAS)、创面出血、肛门坠胀感、尿潴留及肛门控便能力(FISI)评分,比较两组治愈率及复发率情况,比较两组患者术前及术后1年的肛管静息压、肛管收缩压及肛管排便压的差异。结果：治疗组、对照组治愈率分别为87.37%、94.75%,差异无统计学意义(P>0.05);治疗组、对照组复发率分别为7.37%、2.11%,差异无统计学意义(P>0.05);术后第1、3、7天,治疗组VAS评分、创面出血和术后第14天创面出血评分均高于对照组(P <0.01);术后第1、7天,治疗组患者肛门坠胀评分和术后第1天尿潴留评分明显低于对照组(P <0.01);术后1年,治疗组患者肛管收缩压及肛管排便压明显高于对照组...     

经括约肌间瘘管结扎术治疗复杂性肛瘘

目的：评价经括约肌间瘘管结扎术治疗复杂性肛瘘的临床疗效。方法回顾性分析2009年9月至2012年2月间南京中医药大学附属医院肛肠科采用经括约肌间瘘管结扎术治疗的24例复杂性肛瘘患者的临床资料,评价手术疗效及患者术后肛门括约肌自主控制功能。结果一期手术治愈率为66．7％（16／24）。术后单纯括约肌间切口感染2例,经局部应用亲水性纤维含银敷料换药后愈合;4例括约肌间切口感染且内口与肛管内相通,经直接切开后愈合;完全失效2例,其中1例因术后症状持续而行挂线治疗,另1例术后7月复发。临床总治愈率为91．7％（22／24）。术后随访6～44（中位数16）月,克利夫兰肛门失禁评分结果显示,患者均无肛门括约肌自主控制功能下降。结论经括约肌间瘘管结扎术是一种治疗复杂性肛瘘安全有效的保留括约肌手术。     

Comparison between recent sphincter-sparing procedures for complex anal fistulas-ligation of intersphincteric tract vs transanal opening of intersphincteric space

Complex anal fistulas are difficult to treat. The main reasons for this are a higher recurrence rate and the risk of disrupting the continence mechanism because of sphincter involvement. Due to this, several sphincter-sparing procedures have been developed in the last two decades. Though moderately successful in simple fistulas (50%-75% healing rate), the healing rates in complex fistulas for most of these procedures has been dismal. Only two procedures, ligation of intersphincteric fistula tract and transanal opening of intersphincteric space have been shown to have good success rates in complex fistulas (60%-95%). Both of these procedures preserve continence while achieving high success rates. In this opinion review, I shall outline the history, compare the pros and cons, indications and contraindications and future application of both these procedures for the management of complex anal fistulas.     

肛瘘切开挂线联合置管冲洗术对肛门功能的影响

目的探讨肛瘘切开挂线联合置管冲洗术与切开挂线术对高位复杂性肛瘘（CHAF）的肛门功能影响及治疗效果。方法54例CHAF患者随机分为观察组与对照组,对照组行切开挂线术,观察组行切开挂线联合置管冲洗术。结果观察组患者术后创面愈合时间、住院时间及费用分别为19．3±4．5d、12．8±6．7d及2．2±1．3千元,均明显低于对照组（P〈0．05）。肛瘘切开挂线联合置管冲洗术组患者手术后3、6、12个月肛门功能良好率依次为66．7％、74．1％、92．6％,明显高于同期对照组的48．1％、59．3％、77．8％,差异均具有统计学意义（r=7．386、5．050、9．074,P〈0．05）。结论切开挂线联合置管冲洗术对CHAF治愈率高,保护了患者的肛门功能。     

Managing fistula‐in‐ano with ligation of the intersphincteric fistula tract procedure: the Western Hospital experience

Aim To review the preliminary results of the ligation of the intersphincteric fistula tract (LIFT) technique in treating complex anal fistulas at our hospital. Method Between March and November 2010, patients with cryptoglandular anal fistulas were recruited prospectively from the colorectal clinic and treated using the LIFT procedure. A database was set up to collect information on demographics, past surgical treatments, fistula characteristics, MRI scan results, operative data and follow‐up findings. The primary end‐point measured was cure of the disease. The secondary end‐point was the degree of postoperative continence. Preoperative and postoperative incontinence rates were recorded using Wexner’s Incontinence Scale. Results Twenty‐five patients (eight women and 17 men; median age, 40 years) underwent the LIFT procedure. Ten patients had recurrent fistulas and previous fistula surgery. The median operating time was 39 min. No intraoperative complications were documented. The median follow‐up duration was 22 (3–43) weeks. Primary healing was observed in 17 (68.0%) patients and the median healing time was 6 weeks; one wound remained incompletely healed. Seven patients (28.0%) had disease recurrence presenting between 7 and 20 weeks postoperatively. No patients reported any incontinence postoperatively. Conclusion The LIFT procedure has favourable healing rates with little or no risk of incontinence. This operation is safe and easy to learn. The early results from this pilot study show promise and affirm some of the findings of other researchers. These results will suggest opportunities to conduct further controlled studies comparing the LIFT procedure with standard therapies.