医务人员药品不良反应认知度和呈报态度的调查分析

目的：了解嘉峪关市各级医院医务人员对药品不良反应（ADR）的认知水平和呈报态度。方法：分层抽取嘉峪关市三级医院2所、二级医院2所,整群抽取上述医院于调查日在岗的医务人员,进行现场调查,利用手工筛选和Excel建立数据库,SPSS11．5统计软件分析。结果：不同级别医院的医务人员对ADR概念、严重ADR的范畴、引发ADR最多药品的类别等相关知识认知度差异具有显著性（P〈0．05）;而对正式上市的药品是否会引起ADR（认识度较高）、ADR的报告程序认识（认知度差）基本一致（P〉0．05）;不同职业者对药品不良反应知识的认知度差异具有显著性（P〈0．05）,其中药学人员的认知度最高,管理人员认知度最低;不同级别医院的医务工作者对待ADR的态度差异具有显著性（P〈0．05）,态度总体端正但也存在误区。结论：医务人员对ADR的认知水平普遍较差且具显著差异性,应加强宣传教育,提高药品不良反应的认知水平。     

医务人员对药品不良反应认知度和报告态度的调查分析

目的:为促进药品不良反应(ADR)监测工作提供参考。方法:分层抽取萍乡地区三级医院5所、二级医院15所以及一级医院14所,对上述医院在岗的医务人员实施现场问卷调查,建立数据库,利用SPSS 13.0统计软件分析。结果:萍乡地区各级医院医务人员对ADR英文缩写、ADR概念、上市后药品及中药是否存在ADR等知识认知度较好,而对医院ADR监测负责部门、ADR是否为医疗差错、《中华人民共和国药品管理法》是否有ADR法律条文等认知度较差;不同岗位对ADR知识的认知度存在差异,药学人员对ADR的认知度明显高于其他三类人员;医务人员对ADR呈报态度总体基本端正,但也存在误区;医疗卫生机构ADR监测工作还不够深入,工作重视程度不够。结论:应加强ADR知识宣传培训,端正ADR报告态度,增强医务人员报告意识,强化医疗卫生机构重视程度,提高ADR监测水平。     

我院医务人员药品不良反应监测认知度调查分析

目的：了解我院医务人员药品不良反应（ADR）监测相关知识掌握情况,为进一步开展ADR报告和监测工作提供参考。方法：将我院在岗人员分类,分别填写“医务人员ADR监测认知度调查表”,以调查我院医务人员ADR报告与监测认知度情况。结果：我院医务人员对ADR概念认识不足,上报范围不清,上报意识淡薄,对上报程序及ADR管理机构不明,ADR法律意识不强。结论：有必要对医务人员进行ADR监测相关知识的培训,以提高其对ADR监测的认知度,使ADR监测工作成为医务人员的自觉行为。     

对嘉峪关市医务人员药品不良反应认知度的调查与研究

目的了解嘉峪关市各级医院医务人员对药品不良反应(ADR)认知度,为开展ADR监测工作提供参考依据。方法采用调查问卷的形式,对嘉峪关市不同级别医院的医务人员进行抽样调查。结果医务人员对ADR概念、严重ADR的范畴、引发ADR药品类别等相关知识认知度具有显著性差异(P<0.05);不同职业者对药品不良反应知识的认知度差异具有显著性(P<0.05),其中药学人员的认知度最高,管理人员认知度最低。结论应加强有关ADR知识的宣传与培训,提高医务人员对ADR的认知度,提升其在ADR监测工作中的自觉性。     

湖北省医务人员药品不良反应监测认知与行为的调查分析

目的 通过对湖北省医疗机构医务人员药品不良反应（ADR）报告与监测以及安全合理用药知识认知、行为、态度的调查,为深入开展药品安全监管提供新思路。方法 于2019年6—12月分别抽取武汉、恩施、荆州三个地区9家医疗机构共计1673名医务人员进行问卷调查,采用SPSS 22.0和SAS 9.3软件进行统计学分析。结果 医务人员对ADR监测与合理用药整体认知度较高,合格率达到78.24%,但是医务人员对新的ADR的含义（占比44.41%）、严重的ADR的含义（占比45.48%）和关于ADR警告或者行政处罚（占比11.30%）认知度偏低。对于ADR监测法规的认知,不同岗位（P <0.05）、不同年龄（P <0.05）、不同工龄（P <0.05）、不同文化程度（P <0.05）的医务人员有显著性差异;对安全合理用药的认知,不同岗位（P <0.05）、不同年龄（P <0.05）、不同工龄（P <0.05）、不同文化程度（P <0.05）的医务人员也有显著性差异。单因素分析显示,医务人员的岗位、性别、年龄、工龄、文化程度、职称与ADR法规及合理用药整体...     

对我院医务人员药品不良反应认知度的调研

目的:了解医务人员药品不良反应的认知度,为进一步开展ADR报告和监测工作而制订干预措施。方法:对玉溪市人民医院临床、护理、药学在岗人员进行问卷调查,对问卷各项内容进行统计、分析。结果:医务人员对ADR基本概念、相关知识认知度基本正确,对ADR呈报态度总体端正,对ADR监测上报工作总体上形式较好,但还需进一步努力深化开展。结论:有必要加强ADR知识宣传培训,增强医务人员上报意识,并制定干预措施,提高ADR监测水平。     

对医务人员和患者药品不良反应认知水平的调查分析及干预措施

目的:了解医务人员和患者对药品不良反应(ADR)的认知水平,为进一步开展ADR报告和监测工作而制订更加有效的干预措施。方法:对我院医务人员和患者进行现场问卷调查,对问卷各项内容进行统计、分析。结果:医务人员对ADR的定义答对率为62·8%,认为应报告所见ADR占42·9%,但仅有12·3%报告过ADR;认为ADR与医疗纠纷或医疗质量有关占34·1%。患者对ADR知识的认知度是非常欠缺的。结论:医务人员和患者对ADR知识的认知度低直接影响ADR上报率,从而影响药监部门对药品上市后的客观评价。各相关部门有必要加强对医务人员进行ADR知识培训、ADR上报监管,对广大民众进行ADR知识宣教,以提高ADR的上报率。     

湖北省药品不良反应报告和监测工作现状调查与展望

目的 通过了解医疗机构、药品生产企业、药品经营企业的药品不良反应（ADR）的上报情况和工作开展现状及对医药工作者关于ADR知识的认知度调查来找到ADR报告率低的原因,进一步推进ADR报告和监测工作.方法 采取现场查看和随机分层抽样法,对30所涉药单位的ADR报告和监测工作进行调研,对收集、上报的ADR事件报告表进行统计学分析,同时抽取15%的医药人员作为样本对其进行问卷调查,并实施行政干预性的教育和培训.结果 被查单位仅有7个单位向不良反应监测中心上报ADR事件表.在调查的1 090名医药工作者中,59.4%的人员回答曾经遇到ADR,但仅有 42.3%的人员报告过ADR;ADR测试合格率仅占26.68%.通过行政干预培训,医药人员ADR认知度得到显著提高（X^2＝80.728,P＜0.05）.药品生产、经营、使用单位之间认知得分差异有显著性（X^2＝62.277,P＜0.05）,不同层次的单位的医药人员对ADR认知得分差异有显著性（X^2＝167.771,P＜0.05）.此外,不同职业认知得分差异有显著性（X^2＝326.315,P＜0.05）.结论 应加强各涉药单位医药人员关于ADR知识的法规宣传和岗位培训,提高医药工作者对ADR知识的整体认知水平和ADR的报告率;各药品生产、经营、使用单位要高度重视ADR监测工作,建立ADR监测专职机构和专业人员,加大经费投入才能顺利贯彻实施《药品不良反应报告和监测管理办法》.     

我院医务人员药品不良反应认知度调查

目的:了解我院医务人员对药品不良反应(ADR)的认知和重视程度,为开展ADR报告与监测工作制定有效措施。方法:对我院医务人员进行药品不良反应问卷调查,对问卷调查内容进行统计分析。结果:各类医务人员对ADR定义理解完全正确的占63.2%,认为有必要报告ADR的占61.0%,在实际工作中报告过ADR的仅占28.2%。结论:我院医务人员对ADR定义、报告和监测相关制度的认知还不够,应加强ADR培训和上报监管,以提高医疗质量,减少药害事件的发生,促进临床合理用药。     

太原市医务人员药品不良反应认知情况调查研究

目的调查太原市医务人员对药品不良反应（ADR）的认知程度,为进一步促进和完善ADR报告和监测提供参考。方法采用调查问卷的形式,对太原市不同级别医院和诊所的医务人员进行抽样调查。结果太原市医务人员对ADR基本知识如ADR的概念、是否只有新药才发生ADR等有所了解,但存在ADR报告意识淡薄,对报告程序不了解,ADR的法律意识不强等问题。结论应加强有关ADR知识的宣传与培训,提高太原市医务人员对ADR的认知度,提升其在ADR监测工作中的自觉性。同时,应完善ADR监测体系,保障公众用药安全。     

安徽省合肥地区医务人员对药品不良反应认知度和态度的研究

目的了解合肥地区各级医院医务人员对药品不良反应(ADR)认知和态度。方法分层抽取合肥地区三级医院1所、二级医院5所、一级医院7所,整群抽取上述医院于调查日在岗的医务人员,进行现场调查,EPI info 6.04建立数据库,SPSS11.5统计软件分析。结果合肥地区各级医务人员对ADR概念、ADR呈报程序、ADR临床表现特点等知识认知度基本一致(P>0.05);对ADR性质、ADR监测主管部门等认知度差异具有显著性(P<0.05),等级高的医院医务人员认知度通常好于等级低医院,但也有个别问题反之;医务人员对ADR呈报态度总体端正,但也存在误区。结论加强ADR知识宣传培训,端正态度,增强医务人员上报意识,提高ADR监测水平。     

上海市不同专业医务人员药品不良反应报告质量分析

目的研究不同专业医务人员药品不良反应自愿报告情况及医务人员对药品不良反应及其报告制度的认知情况。方法收集2006年1月至2007年12月上海市药品不良反应报告数据库中医务人员的报告数据,导入ACCESS软件,用EXCEL统计分析报告情况及质量。结果本组资料中,来自医师的报告占总报告数的65．87％,高于药师（26．13％）和护士（8．00％）。根据世界卫生组织（WHO）和我国质量分级标准,医务人员ADR报告的级别99％以上达到3级,但报告的基本信息存在缺失,如病历号缺失率高于10％、联系方式高于5％。2006年,医师、药师、护士上报的新的和严重的药品不良反应分别为3．54％、4．20％、5．85％,2007年分别为5．55％、6．33％和12．28％。关联性评价中,护士的评价与市中心的评价一致比例最高。结论医务人员对药品不良反应关注的角度和报告技术要点的掌握并不一致,要提高对药品不良反应的监测效率,必须调动和发挥医务人员的积极性,持续不断地进行教育和培训。     

我院护士药品不良反应认知度的调查

目的了解我院护士对药品不良反应相关知识的认知情况,为提高我院药品不良反应上报率、上报质量及做好不良反应监测工作提供依据。方法利用自制调查问卷的方式,对我院护士进行问卷调查,对问卷各项内容进行数据处理,分析不同层次护士对药品不良反应的概念、相关知识的掌握情况。结果我院护士对药品不良反应相关知识认知度基本正确,能意识到上报药品不良反应的重要性。但还需要再努力开展此项工作。结论进一步加强药品不良反应相关知识的培训。分层次组织护士学习,以提高我院药品不良反应监测水平。     

Reporting of adverse drug reactions by hospital doctors and the response to intervention

Aims In Ireland there are relatively fewer adverse drug reaction (ADR/yellow card) reports from doctors in hospital than in general practice. The aim of this study was to review the attitudes to reporting of ADRs of hospital doctors and to determine the effect of making yellow cards freely available.
Methods A postal survey of actively practising doctors with follow-up of non-responders was undertaken. We addressed the single most frequently claimed deterrent to reporting, unavailability of yellow cards, by making cards prominently available and placing one in patient's chart upon admission. In addition, doctors were regularly reminded that ADRs should be reported.
Results Of 118 hospital based doctors, only 45% had ever reported an ADR. Fewer than 5% of pre-registration house officers had reported an ADR and the likelihood of reporting increased with seniority and was greater among physicians than surgeons. We found no evidence that doctors had published case reports in place of submitting ADR reports. Over 3 months, the greater availability of yellow cards and reminders about reporting ADRs led to an approximate five-fold increase in reports but reporting declined rapidly thereafter when verbal reminders were withdrawn, despite continued ready availability of cards suggesting that making cards available alone does not significantly increase reporting.
Conclusions This study indicates there may be more fundamental constraints to reporting than attitudinal surveys would suggest and we need to explore additional avenues to ensure a 'reporting culture'.     

Developing an adverse drug reaction reporting system at a teaching hospital

Adverse drug reactions (ADRs) are a frequent cause for hospitalization and occur often in hospitalized patients. The objective of this study was to establish an ADR reporting and monitoring system at a teaching hospital. The pharmacovigilance unit of Masih Daneshvari hospital was established by a clinical pharmacist and a clinical pharmacologist. Healthcare professionals were encouraged to report any suspected ADRs encountered in in-patients. The incidence, pattern, seriousness, severity and preventability of the reported ADRs were analysed. During the period of 12 months, for 6840 patients, 112 spontaneous reports were received. The most frequently reported reactions were due to anti-infective agents (58.2%). Ceftriaxone accounted for the highest number of the reported ADRs among anti-infective agents. The skin and appendages system was the most frequently affected system (32.5% of all reactions). Seventeen per cent of the ADRs were reported as serious reactions. Although the incidence of ADRs reported by physicians and nurses was found to be low, this programme was useful as a preliminary programme in initiating a culture of ADR reporting among healthcare professionals. Improved communication between the physicians and nurses with the pharmacovigilance centre in the hospital is suggested.     

药品不良反应及安全用药知识在某三甲医院三类医务人员中认知度研究

目的：研究了解医师、护师、药师三类医务人员对药品不良反应（ADR）以及安全用药相关知识的认知情况,为ADR及临床安全用药监测的深入开展提供参考。方法：利用网上药学问卷调查平台对皖南地区某大型三级甲等医院45个临床科室的医务人员（医师、护师、药师）的ADR以及安全用药相关知识进行网上调查,数据由平台自动导出Excel表格,使用SPSS19．0软件进行统计分析。结果：通过调查平台,获取有效调查问卷575份,医务人员对ADR和安全用药知识的平均知晓率为83．0％,对ADR上报流程平均知晓率为83．4％。三类医务人员（医生、护师、药师）对于“什么是ADR”、“用药错误的含义”等基本概念的知晓程度较高,回答无明显差异（P〉0．05）。对于“药品不良反应／不良反应事件（ADR／ADE）”、“用药错误”的判断,回答存在显著差异（P〈0．001）,医师、护师的知晓程度低于药师。对于“用药后出现ADR的应对措施”、“ADR必须填写的项目”等问题,三类医务人员（医生、护师、药师）问题差异无统计学意义（P〉0．05）,但对于“ADR上报期限”等的回答有显著差异（P〈0．001）,药师的知晓率高于医师、护师。结论：综合分析该院三类医务人员对ADR和安全用药基本知识掌握总体较好,但对于ADR与ADE、用药错误等概念之间差别存在混淆。应以多种形式对医务人员的ADR和安全用药相关知识进行培训、教育,提高医务人员对ADR／ADE、用药错误等的判断能力,加强ADR监测水平和上报意识,提升合理用药水平,保障患者用药安全。     

Knowledge and awareness of adverse drug reactions and pharmacovigilance practices among healthcare professionals in Al-Madinah Al-Munawwarah,Kingdom of Saudi Arabia

Adverse Drug Reactions (ADRs) are scantly reported with poor contribution by healthcare professionals worldwide and in particular in developing countries. The aim of this study was to assess the knowledge and awareness of adverse drug reactions (ADRs) reporting and pharmacovigilance system among healthcare professionals in Al-Madinah Al-Munawwarah hospitals, Kingdom of Saudi Arabia. A questionnaire was designed addressing; awareness of ADRs, knowledge of pharmacovigilance system, availability of ADRs reporting system, patient counseling about ADRs and documentation of ADRs. The questionnaire was distributed to randomly selected healthcare professionals (n = 585) such as physicians, pharmacists, nurses and pharmacists’ technicians of hospitals. Completed questionnaires were collected and data were analyzed. Data were expressed in number as well as percentage. Of the 585 questionnaires circulated, a total of 384 healthcare professionals responded. Healthcare professional categories involved in the study were 148 physicians, 37 pharmacists, 158 nurses and 41 pharmacist technicians. The percent of the respondents who accepted to enroll in the study was 65.64%. Most of the respondents were unable to correctly define the pharmacovigilance term, but they were aware of ADRs. The awareness among healthcare professionals of the national pharmacovigilance system was 39.6%. Pharmacists had a good knowledge of pharmacovigilance and ADRs terminology and showed a more positive attitude to report ADRs. A greater number of the healthcare professionals were aware of ADRs reporting, but practically it is not implemented in hospitals. Most hospitals had follow-up documentation systems, but did not include ADRs reporting. There was no distinct pharmacovigilance system in place. Our study has demonstrated a lack of knowledge and awareness of pharmacovigilance and ADRs reporting among healthcare professionals in hospitals. The poor knowledge of ADRs reporting emphasized the urgent need to implement the appropriate strategies to improve the awareness of pharmacovigilance practices and ADRs reporting in Al-Madinah Al-Munawwarah hospitals.