~(99)Tc~mO_4~-甲状腺显像对亚急性甲状腺炎的诊断价值

目的:探讨甲状腺核素显像对亚急性甲状腺炎的诊断价值。方法:选取53例亚急性甲状腺炎患者使用单光子发射计算机断层成像术(SPECT)进行99TcmO4-甲状腺静态显像,同时选择10例无甲状腺疾病的健康者作为正常对照组。结果:亚急性甲状腺炎患者中36例双叶均隐约显影或不显影,放射性分布与周围软组织本底相似,15例甲状腺仅单叶隐约显影,2例呈单侧冷结节。结论:亚急性甲状腺炎核素甲状腺静态显像有特征性改变,甲状腺核素显像有重要诊断价值。     

放射性核素显像对亚急性甲状腺炎诊断的临床意义

目的探讨放射性核素显像对亚急性甲状腺炎诊断的临床价值。方法对亚急性甲状腺炎患者进行甲状腺99mTc核素静态扫描,并对图像进行分析。结果 89例亚急性甲状腺炎患者中有80例患者双侧甲状腺均不显影或隐约显影,8例患者单侧甲状腺不显影,1例表现为峡部＂凉结节＂。结论亚急性甲状腺炎患者甲状腺核素扫描以双侧甲状腺不显影为主要表现,对疾病的诊断以及疗效判断具有重要价值。     

亚急性甲状腺炎在核素影像的表现

目的:探讨核素显像对亚急性甲状腺炎的诊治价值。方法:对321例亚急性甲状腺炎患者进行~(99m) TcO_4~-甲状腺核素显像,通过影像处理计算颌下腺放射性计数/甲状腺放射性计数的比值。以TIU、TT_4、TT_3、FT_4、FT_3、STSH、TG-Ab、TM-Ab、ESR等项目作为对照。结果:94例甲状腺未显影(++),占29.28%;227例甲状腺双侧或单侧甲状腺轻度显影,影像模糊不清,放射性分布稀疏不均匀(+),占70.72%。结论:亚急性甲状腺炎核素显像结果证实,甲状腺影像的清晰程度与TIU结果的高低呈平行关系,且与亚急性甲状腺炎的病情轻重有关。颌下腺放射性计数/甲状腺放射性计数的比值作为一项半定量指标有助于亚急性甲状腺炎的检出率。甲状腺核素显像不但可用于亚急性甲状腺炎的诊断,而且可作为判断其疗效的一项重要指标。     

多排螺旋CT和SPECT对亚急性甲状腺炎的诊断价值

目的:探讨多排螺旋CT和SPECT核素扫描对亚急性甲状腺炎的诊断价值。方法:经病理证实的100例亚急性甲状腺炎患者,对其多排螺旋CT和SPECT核素扫描影像资料进行回顾性分析,总结归纳其影像特点。结果:100例患者的多排螺旋CT平扫图像均可见甲状腺内斑片状边界模糊的低密度影,SPECT核素扫描见甲状腺显像浅淡且局部有放射性稀疏和缺损表现。SPECT所见稀疏和缺损区与CT图像显示的斑片状低密度影部位相一致,但范围较大。结论:SPECT核素扫描对亚急性甲状腺炎的诊断有重要的临床价值,CT显示甲状腺解剖结构较SPECT清晰,CT具有较高的密度分辨率,可以帮助排除其他疾病,对亚急性甲状腺炎的诊断和鉴别诊断有一定的价值。     

21例亚急性甲状腺炎临床核医学分析

通过对21例亚急性甲状腺炎测定血清T3、T4、TSH(放射免疫分析法)及甲状腺24h吸碘率及甲状腺核素显像分析,发现血清T3、T4、TSH(放射免疫分析)、甲状腺24h吸碘率及甲状腺核素显像联合应用可以较准确的诊断亚急性甲状腺炎.为临床准确诊断,提供了理论依据.     

118例亚急性甲状腺炎核素显像分析

为提高亚急性甲状腺炎的诊断准确性,回顾分析了118例亚急性甲状腺炎核素显像资料。结果:34例甲状腺未显影(++),84例甲状腺双侧或单侧轻度显影,影像模糊不清,放射性分布不均匀(+),无一例甲状腺显像正常者(-),结果表明:甲状腺影像清晰程度与甲状腺吸~(131)碘率高低,亚急性甲状腺炎病情轻重呈平行关系,不但用于亚急性甲状腺炎的诊断,还可作为判断亚急性甲状腺炎疗效的一项重要手段。     

动静态显像对亚急性甲状腺炎诊断的应用

目的 探讨放射性核素甲状腺动静态显像对亚急性甲状腺炎的诊断价值。方法 对临床确诊的１５０例亚急性甲状腺炎患者有γ－照相进行＾９９ｍＴｃ甲状腺动态和静态显像,同时选择５０例健康体查者做正常对照组,另选１０８例甲亢及其它甲状腺疾病一同分析。结果 亚急性甲状腺炎患者中有４３例甲状腺血流灌注明显增多,５０例轻度增多,显像时相提前,占总数的６２％。４５例甲状腺血流减少,显影不清楚,占３０％。静态显像甲状腺腺     

5种疼痛性甲状腺疾病的临床表现特点分析

分析８４例亚急性甲状腺炎、５６例甲状腺结节并出血、４例桥本甲状腺炎、２例甲状腺癌及２例甲状腺瘤的临床表现特点和Ｔ３、Ｔ４、ｒＴ３、ＨＴＧ测定、Ｂ超、吸碘率（ＲＡＩＵ）、核素显像、针吸活检的诊断意义。     

16例亚急性甲状腺炎核医学诊治与探讨

目的探讨核素显像及核医学体外分析技术对亚急性甲状腺炎的诊断价值。方法对16例亚急性甲状腺炎患者进行甲状腺核素显像,影像结果同时由2名以上核医学医师阅片,检测血清FT3,FT4,TSH,测2h甲状腺摄^131I率。间隔2-4周再进行上述检查。结果亚急性甲状腺炎患者FT3,FT4与正常对照组无显著性差异（P〉0.06）;TSH低于正常对照组（P〈0.06）;2h摄^131I率与正常对照组无显著性差异（P〈0.05）;SPECT甲状腺显像见甲状腺局部＂冷结节＂。间隔2-4周后,实验组2 FT3,FT4高于正常对照组,具有显著性差异（P〈0.05）;TSH低于正常对照组（P〈0.05）;2h摄^131I率低于正常对照组,具有显著性差异（P〈0.05）;SPECT甲状腺显像见单侧或两侧甲状腺失去正常形态,放射性摄取降低且分布不均匀。结论亚急性甲状腺炎患者血清TSH降低,甲状腺显像见局部＂冷结节＂。典型的亚急性甲状腺炎因为间隔2-4周后,患者才出现典型的所谓＂分离现象＂才出现,所以核医学检查十分重要。     

核素显像诊断亚急性甲状腺炎的临床价值

亚急性甲状腺炎(简称：亚甲炎)为临床常见甲状腺疾病，通过对该病的核素显像及血清甲状腺激素检测等方法的比较，探讨核素显像对亚甲炎的诊断价值。     

甲状腺结节核素显像的临床价值

目的:评价甲状腺显像鉴别诊断甲状腺结节良、恶性的临床价值。方法:180例甲状腺结节患者行甲状9mTcO4-显像,并将其与病理结果进行对比研究。结果:甲状腺结节显像呈冷结节者158例(87.8%),温结节者7例(3.9%),热结节者3例(1.7%),甲状腺不显影或显影极淡者12例(其病理诊断为“亚急性甲状腺炎”6.7%)。冷结节癌发生率18.4%(29/158例),1例热结节手术病理诊断乳头状癌0级~1级。良、恶性甲状腺结节患者在甲状腺功能及大小上差异有显著性(χ2=5.70,11.49;P<0.05)。结论:甲状腺核素显像仅从影像特性去区分良、恶性还很困难,可结合其他检查作出初步诊断。     

CHRONIC LYMPHOCYTIC THYROIDITIS IN ENDEMIC GOITER

ChroLnic lymphocytic thyroiditis and lympho- cyte infiltration were studied in 2,053 cases of endemic goiter. Only 7 cases of chronic lympho- cytic thyroiditis and 3 0f focal thyroiditis showed diffused enlargement of thyroid. Among 2,053 cases, 150 had thyroiditis (7.3%), of whom 137 (7.1%) were accompanied by nodular goiters. If focal thyroiditis was excludetl, the incidence rate of chronic lymphocytic thyroiditis would be 2.39T% The increased incidence of Hashimoto's disease was considered to he due to the decreased incidence of endemic goiter and the neglect of chronic lymphocytic thyroiditis accompanied by nodular goiters. Thyroiditis occurs in the sur- rounding tissues of the nodule, and it is why the changes in thyroiditis were overlooked iii excised nodules.     

Detection of thyroid malignancy in a hot nodule by fluorine-18-fluorodeoxyglucose positron emission tomography

Carcinoma of the thyroid arising in an autonomously functioning or "hot" nodule is uncommon. The majority of thyroid carcinomas present as a "cold" nodule on radionuclide scintigraphy. We report a poorly-differentiated thyroid carcinoma developing in a long-standing "hot" nodule in a 51-year-old Chinese woman. Fluorine-18-fluorodeoxyglucose positron emission tomography (FDG PET) showed focal FDG uptake in the thyroid nodule, as well as in the cervical and pulmonary hilar lymph nodes. This case illustrates that the incidence of thyroid carcinoma in a "hot" nodule is not negligible. The role of FDG PET in the differentiation of benign from malignant thyroid nodules is still unclear. In contrast, FDG PET has been shown to have a role in the follow-up of thyroid cancer patients after thyroidectomy and subsequent radioactive iodine-131 (I-131) ablation. It may be useful in the identification and localisation of recurrent cancer foci in patients with elevated thyroglobulin levels but a negative I-131 whole body scan.     

甲状腺~(99)Tc~mO_4~-显像冷结节的临床诊断价值

目的　探讨甲状腺99TcmO-4 显像冷结节对不同性质甲状腺疾病的诊断价值。方法　采用静脉注射99TcmO-4 185MBq ,2 0min后甲状腺前位静态显像 ,采集总计数 1× 10 6。显像显示甲状腺结节局部放射性分布缺损或低于正常甲状腺组织则定性为冷结节。结果　 34 2例甲状腺99TcmO-4 显像发现冷结节 85例 ,发生率为2 4.9% ,85例冷结节中 ,37例 (4 3.5 % )为甲状腺瘤 ,15例为甲状腺癌 (17.6 % ) ,2 0例 (2 3.5 % )为结节性甲状腺肿 ,8例 (9.4% )为甲状腺炎 ,4例 (4 .7% )为单纯性甲状腺囊肿 ,1例 (1.3% )为甲状腺外肿物。结论　冷结节在甲状腺99Tcm O-4 显像时较为常见 ,且不同性质甲状腺疾病的冷结节及其周围组织有一定的特征性表现 ,因此99TcmO-4显像冷结节对甲状腺腺瘤、甲状腺癌、甲状腺囊肿、甲状腺炎等常见疾病具有较高的临床价值。     

放射性甲状腺癌合并慢性放射性甲状腺炎的相关问题探讨

目的探讨放射性甲状腺癌合并慢性放射性甲状腺炎的病理特点、诊断及两者的相关性。方法回顾分析汉中市中心医院肿瘤外科2011年6月~2013年7月收治的3例放射性甲状腺癌合并慢性放射性甲状腺炎患者的临床资料,对照国家制定的放射性甲状腺癌与慢性放射性甲状腺炎的诊断标准,进行分析探讨。结果 3例患者术后病理类型为甲状腺乳头状癌合并慢性淋巴细胞性甲状腺炎;根据最新诊断标准,2例诊断为放射性甲状腺癌合并慢性放射性甲状腺炎,1例仅诊断为甲状腺乳头状癌合并慢性放射性甲状腺炎,不能诊断为放射性甲状腺癌。结论放射性甲状腺癌的绝大多数病理类型为甲状腺乳头状癌;慢性淋巴细胞性甲状腺炎是慢性放射性甲状腺炎是一种病理类型;从事放射介入工作时间3年8个月,甚至更短时间,就能发生放射性甲状腺癌;慢性放射性甲状腺炎可以转变为放射性甲状腺癌。     

甲状腺结节283例放射性核素扫描的临床分析

本文分析了283例甲状腺结节扫描结果，并与病理诊断对照。其中热结节18例（占6．36％）；温结节35例（12．37％）；冷结节230例（81．27％）。经病理证实：良性肿瘤250例（占88．34％）；恶性肿瘤16例（5．65％）；其它甲状腺疾病17例（6．01％）。恶性肿瘤病例全部发生在扫描结果为冷结节的病例中。     

Malignancy in solitary solid cold thyroid nodule

Solitary thyroid nodule is a common endocrine problem. The main concern of solitary thyroid nodule lies in excluding the malignancy & to operate on as few patients as possible. Other than history & clinical examination, hormone assessment, USG of thyroid gland, radionuclide scan & FNAC were used to differentiate malignant nodules from benign ones. In this study 127 cases with solitary thyroid nodule of all age group & both sexes were included from Endocrine & Thyroid clinic of BSMMU. They were clinically & biochemically euthyroid & had cold nodule on radionuclide scan. USG & FNAC were done & subsequently they underwent surgical procedure. On the basis of postoperative histopathological report the specimens were divided into benign & malignant groups. All the nodules were cold among which 104 were solid & 23 were mixed in consistency. Of the 104 solid cold nodules histopathology revealed 36(34.6%) malignant & 68(65.4%) benign cases. From the 23 mixed cold solitary nodule 5(21.7%) appeared malignant & 18(78.3%) were benign. So malignancy was higher in solid cold group than the mixed cold one but this was not statistically significant (p=0.673). FNAC was done & it revealed that 83(65.5%) cases were benign, 10(7.8%) cases were suspicious & 34(26.7%) were malignant. Finally histopathology showed 41(32.3%) cases were positive & 86(67.7%) cases were negative for malignancy.     

Managing the solitary thyroid nodule

Solitary thyroid nodules are commonly seen in surgical outpatient clinics. A detailed history and a careful physical examination are essential. In the management of the solitary thyroid nodule, fine needle aspiration cytology has become the cornerstone investigation. Ultrasound cannot differentiate between benign and malignant nodules, however is useful in the follow-up period to identify any further nodular growth. As thyroid malignancy occurs in both hot and cold nodules, radionuclide scans are not useful in the management of solitary thyroid nodules. We have attempted to outline the process of managing the solitary thyroid nodule and discuss the options available.     

超声引导下甲状腺细针穿刺在甲状腺疾病诊治中的临床应用评价

目的:提高超声引导下甲状腺细针穿刺(US-FNAB)对于甲状腺疾病的诊断水平?方法:回顾性分析南京医科大学第一附属医院内分泌科2011年5月~2012年1月1 016份US-FNAB细胞病理报告,同时对比分析其中44例接受外科手术患者的组织病理报告?结果:1 016例报告中怀疑或确定为恶性肿瘤72例(7.09%),132例诊断为甲状腺囊性变,占12.99%?明确诊断慢性淋巴细胞性甲状腺炎165例(16.24%)?亚急性甲状腺炎56例(5.51%)?对44例接受手术患者的资料进一步分析得出,US-FNAB对于恶性或怀疑为恶性疾病诊断的敏感性为65.22%,特异性为76.19%,阳性预测值为75.00%,阴性预测值为66.67%,假阳性率为25.00%,假阴性率为33.33%?总体阳性细胞率85.24%?结论:US-FNAB对于甲状腺良恶性结节的鉴别,对于甲状腺囊性变?慢性淋巴细胞性甲状腺炎?亚急性甲状腺炎的细胞病理诊断有非常重要的价值?     

甲状腺“冷”结节~(99)Tc~m-MIBI显像对甲状腺癌诊断的初步探讨

目的　探讨99Tcm MIBI显像在甲状腺癌诊断中的价值。方法　对 51例99TcmO- 4甲状腺显像为“冷”结节的患者行99Tcm MIBI显像。患者均行外科手术治疗 ,并作病理检查。结果　 1 6例病理检查证实为甲状腺癌患者中 ,1 2例99Tcm MIBI显像阳性 ;35例良性病变患者中 ,5例99Tcm MIBI显像阳性。99Tcm MIBI显像对甲状腺癌诊断的灵敏度、特异性和准确性分别为 75 .0 %、85 .7%和 82 .4%。结论　甲状腺“冷”结节行99Tcm MIBI显像对于甲状腺癌的诊断具有重要的临床参考价值