舌淀粉样变性1例

男性,63岁,因舌体发硬不适2个月入院。检查见舌面鲜红,呈镜面舌样改变,表面有细浅沟纹,舌缘有齿痕,舌体质硬,活动受限,伸舌时舌尖不能抵唇部。双侧颊部近口角处可触及对称性硬结,约2．0cm×1．5cm×1．0cm,界限不清,无压痛。     

舌淀粉样变性误诊一例

舌淀粉样变性误诊一例张怀美校哲蒯宝林患者女性，５０岁，维吾尔族，农民。因颏下及双侧颌下肿大３月，于１９９５年８月１５日入院。患者于３个月前患“扁桃体炎”，愈后５ｄ发现颏下肿胀，诊治无效。双侧颌下逐渐肿大，增至鸡蛋大小，伴全身疲乏，头晕，言语不清，影响...     

舌淀粉样变性1例

1　病例介绍患者 ,男 ,64岁。因“发现舌部结节 4月”来第四军医大学口腔医院牙周黏膜病科就诊。患者曾因乏力 ,全身骨痛 2年先后 4次在第四军医大学西京医院住院并行常规化疗。确诊为 :①多发性骨髓瘤ⅢB(IgA型 ) ;②慢性肾功能不全 (失代偿期 )。体检见患者轻度贫血貌 ,左右肩胛骨处均可触及一包块 ,左侧为 6.0cm× 6.5cm大小 ,右侧为 3 .0cm× 2 .5cm大小。局部无红肿 ,无压痛 ,活动自如。双侧颈部、锁骨上、腋窝及腹股沟可触及多个肿大淋巴结 ,有压痛 ,与周围组织粘连。舌背部广泛分布圆形或椭圆形大小不等的结节状突起 ,触之稍硬有弹…     

舌、颏下、颌下淀粉样变性1例

颌面部淀粉样变性极罕见 ,我院于 2 0 0 1年 3月 1日收治 1例舌、颏下、颌下淀粉样变性现报道如下 :患者张某某 ,5 9岁 ,因舌、颏下、颌下无痛性肿大 2年 ,吞咽困难 7个月入院。两年前无意中发现舌、颏下及双侧颌下区肿大 ,发音不清 ,进行性加重 ;7个月前出现吞咽困难 ,睡眠时偶有憋气。于当地医院经CT、B超检查示 :舌、口底肌层广泛增厚。颏下区活检 :肌细胞部分萎缩 ,肌间脂肪细胞增生 ,血管玻璃样变性。检查 :双侧颌下及颏下区弥漫性肿大 ,范围约 15cm× 6cm× 3cm大小 ,表面无红肿 ,皮温正常 ,无压缩性及凹陷性水肿 ,体位实验阴性。舌…     

多发性骨髓瘤伴口腔淀粉样变性1例报告及文献复习

多发性骨髓瘤是浆细胞病中最常见的一种类型,但同时伴发口腔多部位淀粉样变性的病例罕见,其临床表现复杂多样,易误诊、漏诊,从而延误治疗,危及生命.本文报告多发性骨髓瘤合并舌、牙龈、颊、髁突等多处淀粉样变性1例,并进行相关文献复习.     

颈部多发性淋巴结淀粉样变性1例

1例双侧颈部肿物渐增大8年的患者,因出现憋气感就诊。经穿刺和切取活检,诊断为颈部淋巴结淀粉样变性,行肿物切除后康复出院。局限于颈部的多发性淋巴结淀粉样变性是十分罕见的。本文通过此病例,复习相关文献,以供临床参考。     

舌寻常疣1例

患者,男,53岁,工人,因生殖器尖锐湿疣收入我院皮肤科,行激光治疗,因舌部包块转入我科。口腔检查见:舌背前中份左侧可触及1cm×1cm×0.5cm和0.5cm×0.5cm×0.5cm包     

原发性舌部的淀粉样物质沉积症：附4例报告

本文报告４例原发性舌部的ＡＭＳ，并对其进行了１年－２．５年的追踪观察，无论在临床上还是在实验室检查方面未发现明显的全身症状，同时对该病的发病机理，诊断，临床表现及治疗进行了讨论。     

口腔活组织检查在诊断淀粉样变性中的应用

目的:探讨口腔组织(如牙龈、舌、下唇和唇腺)活检,对诊断淀粉样变性的临床意义。方法:对2010-05-2012-04期间,38例疑诊为淀粉样变性的病例行口腔组织活检。其中牙龈活检30例(含同时行唇腺活检2例),舌活检7例,下唇活检1例。所有活检标本送病理科,行HE染色和刚果红特染。结果:经口腔组织活检确定淀粉样变性阳性标本13例。在阳性病例中,活检部位牙龈6例、舌5例、下唇组织1例、唇腺1例。阳性的淀粉样变性病理诊断可提供淀粉样变性确诊依据。在25例阴性病例中,仍有2例通过腹壁脂肪活检、1例经前臂脂肪活检和1例经肾活检电镜观察后,其淀粉样变性诊断得以确定。结论:口腔组织活检具有易于取材、创伤小、恢复快的优点,可作为淀粉样变性的一个重要诊断依据。     

综合治疗大范围口腔黏膜恶性黑色素瘤（附1例报告）

口腔黏膜发生恶性黑色素瘤临床少见,预后极差。本文报告综合治疗1例腭部大范围恶性黑色素瘤,并对口腔黏膜恶性黑色素瘤的病因、各种治疗方法的疗效及影响预后的因素进行了讨论。原发灶冷冻、手术以及免疫治疗等综合治疗应是目前提倡的治疗方法之一。     

口腔黏膜恶性黑色素瘤1例病例报告及文献复习

目的探讨口腔黏膜恶性黑色素瘤的临床诊断及鉴别诊断要点。方法主诉拔牙后持续牙龈出血患者1例,其临床表现为口腔黏膜大面积黑色病损,经全面临床检查结合常规病理及免疫组织化学检查明确诊断。结果临床表现、病理检查和免疫组织化学检查证实为口腔黏膜恶性黑色素瘤。结论对发生于口腔黏膜的黑色损害特别是进展迅速且有破溃出血者应高度警惕口腔黏膜恶性黑色素瘤的可能,并结合临床表现、病理表现及免疫组织化学进行早期诊断和鉴别诊断。     

Amyloidosis with oral involvement. Case report

A patient with chronic renal failure was investigated after complaining of oral discomfort which was found to be due to macroglossia and generalized involvement of the oral soft tissues by amyloidosis. A search for multiple myeloma proved to be positive. She also had a previous history of Carpal-tunnel syndrome. Despite an initial good response to treatment with phenylalanine nitrogen mustard (melphalan hydrochloride), she finally succumbed to end-stage renal failure.     

An Unusual Occurrence of Epidermoid Cyst in the Buccal Mucosa: A Case Report with Review of Literature

Intraoral dermoid and epidermoid cysts are rare and account for less than 0.01% of all the cysts in the oral cavity. A large majority of the same arise in the floor of the mouth and infrequently in other sites. These cysts often remain asymptomatic for years until they reach a size that interferes with mastication, speech and rarely, breathing. However, they also can become acutely symptomatic if they are secondarily infected. We would like to report a case of a rare epidermoid cyst in the buccal mucosa with its differential diagnosis and a review of literature.     

Oral Verrucous Hyperplasia: A Case Report

Oral verrucous hyperplasia is a whitish or pinkinsh elevated pre malignant lesion which occurs rarely. Its is also considered to be an early form of verrucous carcinoma. We have reported a case of verrucous hyperplasia which was diagnosed and treated with buccal fat pad as graft.     

应用Z成形术矫正舌系带过短38例报告

应用Z成形术治疗舌系带过短38例取得满意疗效其中男22例,女16例,手术年龄6个月～6岁。术后无感染、伤口裂开、舌黏连等并发症,伤口愈合快,舌体运动正常,术后1周检查舌前伸由术前的13．5mm增加到术后24．6mm,上举由术前的4．8mm增加到术后20．6mm。     

Benign Fibrous Histiocytoma: A Rare Case Report and Literature Review

Fibrous histiocytoma is a benign soft tissue tumour that may present as a fibrous mass anywhere in the human body. The involvement of the oral cavity is extremely rare and very few cases have been reported in literature till date. We here report a case of benign fibrous histiocytoma localized in the oral cavity. The clinical and histological features of the lesion are discussed precisely in the light of a literature review of this pathology in oral cavity.     

上下颌牙龈同时发生恶性黑色素瘤1例报告及文献复习

口腔黏膜发生恶性黑色素瘤临床少见，本文报告1例上下颌牙龈同时发生恶性黑色素瘤并进行了相关文献复习。对口腔黏膜恶性黑色素瘤的病因、各种冶疗方法的疗效及影响预后的因素进行了讨论。认为包括原发灶令冻手术以及免疫治疗等的综合治疗应是目前提倡的治疗方法。     

Tongue Spindle Cell Rhabdomyosarcoma: A Rare Case Report and Literature Review

Rhabdomyosarcoma (RMS) is a malignant soft tissue neoplasm with its origin in the skeletal muscle and is extremely rare in adults. By the World Health Organization (WHO), a new variant of RMS has been classified, i.e. the spindle cell (Sc) and sclerosing (S) RMS. While the Sc-RMS shows intersecting fascicles of nonpleomorphic spindle cells, the S-RMS is characterized by a marked hyalinization in a pseudovascular growth pattern associated with round-to-spindled tumour cells. According to the analysed data, the Sc/S-RMS variant has a worse outcome than other variants. The new classification of the Sc/S-RMS variant is valuable to the clinical practice. There are not many oral Sc/S-RMS cases reported. The aim of this paper is to demonstrate that an early diagnosis, an adequate treatment and a multidisciplinary approach have a positive effect on the prognosis of the patient. In this study, we analyse a new case of Sc-RMS variant in a young adult with an early diagnosis and a favourable outcome as a result of an appropriated multidisciplinary treatment: early surgery, radiotherapy and chemotherapy treatment.     

A rare case of localised oral amyloid of the labial mucosa

Amyloidosis is often a systemic process, and localised oral amyloidosis is rare. We present the case of a young woman with amyloid deposition in the labial mucosa of her lower lip. Systemic involvement was excluded by comprehensive assessment at the UK Amyloidosis Centre. Of 40 previously reported cases of localised oral amyloidosis we found only one that was limited to the labial mucosa.